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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2017, Volume 37, Issue 8, pp. 1462 - 1469
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2576
Journal Article
Hypertension, ISSN 0194-911X, 07/2019, Volume 74, Issue 1, pp. 73 - 82
Cardiotonic steroids (CTSs) are NKA α-1 (Na/K-ATPase α-1) ligands that are increased in volume expanded states and associated with cardiac and renal diseases.... 
FIBROSIS | MARINOBUFAGENIN | epithelial cells | cardiac glycosides | IDENTIFICATION | mice | macrophages | NA/K-ATPASE INHIBITION | LIGANDS | COLLAGEN-SYNTHESIS | INFLAMMATION | CARDIAC-HYPERTROPHY | PERIPHERAL VASCULAR DISEASE | animals | CHRONIC KIDNEY-DISEASE | ENDOGENOUS DIGITALIS
Journal Article
Biochemistry (Moscow), ISSN 0006-2979, 2/2018, Volume 83, Issue 2, pp. 140 - 151
Binding to Na+,K+-ATPase, cardiotonic steroids (CTS) activate intracellular signaling cascades that affect gene expression and regulation of proliferation and... 
Biochemistry, general | Biomedicine, general | ouabain | toxicity | cardiotonic steroids | Microbiology | JNK | digoxin | primary cultures of neurons | Bioorganic Chemistry | Life Sciences | ERK1/2 | p38 | Na + ,K + -ATPase | bufalin | MAP kinases | ATPase | CELLS | APOPTOSIS | Na+,K+-ATPase | ENDOGENOUS OUABAIN | PRIMARY CULTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | NA/K-ATPASE | IN-VITRO | NA+/K+-ATPASE | Digoxin - metabolism | Rats, Wistar | Ouabain - toxicity | JNK Mitogen-Activated Protein Kinases - metabolism | Neurons - cytology | Cerebrum - cytology | Ouabain - metabolism | Bufanolides - metabolism | Neurons - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Neurons - drug effects | Cell Survival - drug effects | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Ouabain - chemistry | Cells, Cultured | Rats | Digoxin - chemistry | Microsomes - enzymology | Enzyme Activation - drug effects | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Bufanolides - toxicity | Digoxin - toxicity | Bufanolides - chemistry | Mitogen-Activated Protein Kinase 1 - metabolism | Cardiotonic agents | Neurons | Patient outcomes | Cellular control mechanisms | Genotype | Genetic aspects | Cellular signal transduction | Steroids (Drugs) | Health aspects | Cardiac glycosides | Cell proliferation | Cell culture | Digoxin | Toxicity | Ouabain | Intracellular signalling | Activation | Biochemistry | Kinases | Proteins | Cascades | Inhibition | Incubation | Cortex | Extracellular signal-regulated kinase | MAP kinase | JNK protein | Na+/K+-exchanging ATPase | Gene expression | Intracellular | Protein interaction | Steroid hormones | Steroids | Apoptosis | Biological Sciences | K+-ATPase | Cell Biology | Naturvetenskap | Biologiska vetenskaper | Na+ | Natural Sciences | Cellbiologi
Journal Article
Pathophysiology, ISSN 0928-4680, 2007, Volume 14, Issue 3, pp. 159 - 166
Cardiotonic steroids (CS) such as ouabain, digoxin and bufalin, are steroidal drugs prepared from the seeds and dried leaves of the genus Digitalis, and the... 
Endogenous cardiotonic steroids | Endocytosis | Digoxin | Ouabain | Cardenolides | Na, K-ATPase | Cardiac contractility | Bufalin
Journal Article
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, ISSN 0960-0760, 07/2019, Volume 191
Cardiotonic steroids such as ouabain are potent inhibitors of the sodium pump and have been widely used for centuries in the treatment of congestive heart... 
ENDOGENOUS OUABAIN | Lipid droplet | Perilipin | BOVINE ADRENOCORTICAL-CELLS | K+-ATPASE | NA,K-ATPASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Ouabain | Sodium pump | BRAIN OUABAIN | SERTOLI | Leydig cells | ENDOCRINOLOGY & METABOLISM | NA+/K+-ATPASE | Steroidogenesis | ACTIVATED PROTEIN-KINASES | EXPRESSION | LIPID DROPLETS
Journal Article