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Oncotarget, ISSN 1949-2553, 07/2016, Volume 7, Issue 27, pp. 41857 - 41869
Treatment of metastatic renal cell carcinoma (mRCC) with agents that block signaling through vascular endothelial growth factor receptor 2 (VEGFR2) induces... 
anti-angiogenic therapy | renal cell carcinoma | ALK-1 | dalantercept | VEGF | ADVANCED CANCER | HEREDITARY HEMORRHAGIC TELANGIECTASIA | ANGIOGENESIS | ENDOGLIN | CELL BIOLOGY | RECEPTOR-LIKE KINASE-1 | GENE-EXPRESSION DATA | ANTIANGIOGENIC THERAPY | ENDOTHELIAL-CELLS | MOUSE MODEL | GROWTH | Activin Receptors, Type II - metabolism | Kidney Neoplasms - genetics | Humans | Activin Receptors, Type II - antagonists & inhibitors | Carcinoma, Renal Cell - genetics | Imidazoles - administration & dosage | Indazoles - administration & dosage | Immunoglobulin Fc Fragments - administration & dosage | Indoles - administration & dosage | Receptors, Vascular Endothelial Growth Factor - metabolism | Pyrroles - administration & dosage | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Activin Receptors, Type II - administration & dosage | Female | Neovascularization, Pathologic - prevention & control | Tumor Burden - genetics | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Vascular Endothelial Growth Factor - genetics | Carcinoma, Renal Cell - drug therapy | Carcinoma, Renal Cell - blood supply | Recombinant Fusion Proteins - administration & dosage | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Animals | Tumor Burden - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Activin Receptors, Type II - genetics | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Neovascularization, Pathologic - metabolism | Kidney Neoplasms - drug therapy | Kidney Neoplasms - blood supply | Index Medicus
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 11/2018, Volume 19, Issue 11, pp. 1006 - 1014
Objectives: The study was designed to investigate the tumor vessel-associated CD105 expression in monocytes from tumor tissue and peripheral blood (PB) in... 
sunitinib | CD105 | immunohistochemistry | hepatocellular carcinoma | real-time quantitative PCR | CHEMOEMBOLIZATION | CANCER CELLS | ONCOLOGY | GROWTH | ENDOGLIN CD105 | BETA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 4, pp. 1451 - 1455
Preeclampsia is a relatively common pregnancy-related disorder. Both maternal and fetal lives will be endangered if it proceeds unabated. Recently, the... 
Hypertension | Pregnancy | Animal models | Reproduction | Placenta | Fetal growth retardation | Preeclampsia | Blastocyst | Blood pressure | Female animals | Hemolytic anemia, elevated liver enzymes, and low platelet count | Trophoblast | 3-hydroxy-3-methyl-glutaryl-CoA | LOVASTATIN | ANGIOGENESIS | LENTIVIRUS | MULTIDISCIPLINARY SCIENCES | SOLUBLE ENDOGLIN | hemolytic anemia, elevated liver enzymes, and low platelet count | PREGNANCY | GENE-TRANSFER | FETAL | trophoblast | SIMVASTATIN | HYPERTENSION | EXPOSURE | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Pre-Eclampsia - genetics | Humans | Pregnancy Proteins - genetics | Male | Pregnancy Proteins - metabolism | Pre-Eclampsia - prevention & control | HEK293 Cells | Female | Lentivirus - genetics | Pre-Eclampsia - metabolism | Disease Models, Animal | Vascular Endothelial Growth Factor Receptor-1 - genetics | Animals, Newborn | Pravastatin - pharmacology | Cell Line | Transduction, Genetic | Injections, Intraperitoneal | Mice, Transgenic | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Placenta - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Pravastatin - administration & dosage | Placenta Growth Factor | Mice | Development and progression | Models | Dosage and administration | Drug therapy | Pravastatin | Vascular endothelial growth factor | Health aspects | Enzymes | Animal reproduction | Cell growth | Rodents | Kinases | Gene expression | Index Medicus | Biological Sciences
Journal Article
Journal Article
Leukemia Research, ISSN 0145-2126, 2015, Volume 39, Issue 12, pp. 1467 - 1472
Journal Article
Cancer Research, ISSN 0008-5472, 01/2001, Volume 61, Issue 2, pp. 526 - 531
Endostatin, a fragment of the COOH-terminal domain of mouse collagen XVIII is a recently demonstrated endogenous inhibitor of tumor angiogenesis and... 
GENE | ONCOLOGY | ANGIOGENESIS INHIBITORS | ANGIOSTATIN | MICE | TUMOR-GROWTH | EXPRESSION | BINDING | CANCER | ENDOGLIN CD105 | Immunohistochemistry | Genetic Therapy | Neoplasm Transplantation | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor A | Vascular Endothelial Growth Factors | Receptors, Cell Surface | RNA, Messenger - metabolism | Receptors, Growth Factor - genetics | Endoglin | In Situ Hybridization | Lymphokines - genetics | Injections, Intralesional | Mammary Neoplasms, Experimental - pathology | Plasmids - genetics | Female | Mammary Neoplasms, Experimental - blood supply | Neovascularization, Pathologic - prevention & control | Collagen - genetics | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Peptide Fragments - genetics | Collagen Type XVIII | RNA, Messenger - genetics | Platelet Endothelial Cell Adhesion Molecule-1 - analysis | Treatment Outcome | Mammary Neoplasms, Experimental - therapy | Animals | Image Processing, Computer-Assisted | Receptor Protein-Tyrosine Kinases - genetics | Mice, Nude | Endothelial Growth Factors - genetics | Neovascularization, Pathologic - genetics | Endostatins | Mice | Mice, Inbred BALB C | Vascular Cell Adhesion Molecule-1 - analysis | Proto-Oncogene Proteins c-bcl-2 - genetics | Fluorescent Dyes | Plasmids - administration & dosage | Antigens, CD | Index Medicus
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 2/2015, Volume 75, Issue 2, pp. 343 - 352
Inhibition of tumor angiogenesis is an effective mechanism to limit tumor growth; dual inhibition may result in additional benefit. Bevacizumab is a monoclonal... 
Intetumumab | Angiogenesis | Phase I | Medicine & Public Health | Oncology | Cancer Research | Pharmacology/Toxicology | Bevacizumab | MIGRATION | METASTASIS | ENDOGLIN | MONOCLONAL-ANTIBODY | ALPHA(V)BETA INTEGRIN | BREAST-CANCER | COLORECTAL-CANCER PATIENTS | ONCOLOGY | ENDOTHELIAL-CELLS | SOLUBLE E-SELECTIN | PHARMACOLOGY & PHARMACY | Neoplasms - metabolism | Paxillin - metabolism | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Antineoplastic Agents - administration & dosage | Neoplasms - drug therapy | Neovascularization, Pathologic - pathology | Dose-Response Relationship, Drug | Angiogenesis Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neovascularization, Pathologic - drug therapy | Angiogenesis Inhibitors - therapeutic use | Biomarkers, Tumor - metabolism | Adult | Female | Aged | Angiogenesis Inhibitors - adverse effects | Antimitotic agents | Medical research | Care and treatment | Endothelial growth factors | Analysis | Monoclonal antibodies | Medicine, Experimental | Antineoplastic agents | Integrins | Tumors | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 16, pp. 4633 - 4641
Endoglin (CD105) is an endothelial cell membrane receptor highly expressed on proliferating tumor vasculature, including that of hepatocellular carcinoma... 
Niacinamide - analogs & derivatives | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Young Adult | Carcinoma, Hepatocellular - drug therapy | Phenylurea Compounds - adverse effects | Niacinamide - pharmacokinetics | Adult | Female | Phenylurea Compounds - pharmacokinetics | Headache - chemically induced | Liver Neoplasms - drug therapy | Niacinamide - adverse effects | Antibodies, Monoclonal - pharmacokinetics | Epistaxis - chemically induced | Treatment Outcome | Niacinamide - administration & dosage | Disease-Free Survival | Animals | Liver Neoplasms, Experimental - drug therapy | Phenylurea Compounds - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Cell Line, Tumor | Aged | Mice, Inbred BALB C | Myocardial infarction | Drugs | Toxicity | Immunoglobulin G | Stenosis | Cytotoxicity | Hepatocellular carcinoma | Dosage | Hemorrhage | B7 antigen | Recruitment | Confidence intervals | Infusion | Angiogenesis | Liver cancer | Endoglin | Quality | Bioindicators | Vascular endothelial growth factor | CD105 antigen | Pharmacology | Patients | Survival | Endothelial cells | Endothelium | Cirrhosis | Magnetic resonance imaging | Experimental design | Medical prognosis | Monoclonal antibodies | Biomarkers | Hypoxia | Infarction | Plasma levels | Pharmacokinetics | Apoptosis | Cancer | Index Medicus
Journal Article
Anticancer Research, ISSN 0250-7005, 08/2016, Volume 36, Issue 8, pp. 3953 - 3959
Journal Article
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 34, pp. 5802 - 5811
Abstract Vascular endothelial growth factor (VEGF) has been known as a potential vasculogenic and angiogenic factor and its receptor (VEGFR2) is a major... 
Allergy and Immunology | VEGFR2 | Self-immunization | Bacteriophage T4 | Cancer therapy | MEDICINE, RESEARCH & EXPERIMENTAL | DENDRITIC CELLS | CTL RESPONSES | EXTRACELLULAR DOMAIN | IMMUNOLOGY | FACTOR RECEPTOR | THERAPY | COLORECTAL-CANCER | IN-VIVO | ANTITUMOR IMMUNITY | CARCINOMA | ENDOTHELIAL GROWTH-FACTOR | Recombinant Fusion Proteins - immunology | Immunotherapy - methods | Cell Proliferation | Carcinoma, Lewis Lung - therapy | Bacteriophage T4 - immunology | Cancer Vaccines - pharmacology | Vaccines, Synthetic - pharmacology | Carcinoma, Lewis Lung - immunology | Adoptive Transfer | Vaccines, Synthetic - immunology | Vascular Endothelial Growth Factor Receptor-2 - immunology | Carcinoma, Lewis Lung - blood supply | Endoglin | Angiogenesis Inhibitors - administration & dosage | Neovascularization, Pathologic - prevention & control | Neovascularization, Pathologic - immunology | Vascular Endothelial Growth Factor Receptor-2 - administration & dosage | Neovascularization, Pathologic - therapy | Recombinant Fusion Proteins - administration & dosage | Lung Neoplasms - blood supply | Enzyme-Linked Immunosorbent Assay | Endothelial Cells - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - blood | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Bacteriophage T4 - genetics | Enzyme-Linked Immunospot Assay | Lung Neoplasms - therapy | Intracellular Signaling Peptides and Proteins - blood | Cancer Vaccines - immunology | Lung Neoplasms - immunology | Animals | Mice | Vaccines, Synthetic - administration & dosage | Autoimmunity | Animal experimentation | Immunoglobulins | Care and treatment | Autoantibodies | Lung cancer | T cells | Endothelium | Cancer vaccines | Analysis | Immunotherapy | Vascular endothelial growth factor | Enzyme-linked immunosorbent assay | Tumors | Cancer | Biological products | Atoms & subatomic particles | Genomes | Kinases | Experiments | Cancer therapies | Proteins | Studies | Nanoparticles | Angiogenesis | E coli | Plasmids | Lymphocytes | Rodents | Ligands | Deoxyribonucleic acid--DNA | Immune system | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2018, Volume 13, Issue 2, pp. e0188845 - e0188845
Journal Article