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Biochemical Journal, ISSN 0264-6021, 11/2011, Volume 439, Issue 3, pp. 349 - 374
Journal Article
Current Biology, ISSN 0960-9822, 05/2018, Volume 28, Issue 10, pp. 1522 - 1535.e5
The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is the expansion of a hexanucleotide repeat in a... 
alfa-1,lysosome | endolysosome | FTD | C9orf72,C. elegans | ALS | phagosome | SMCR8 | yolk | C9orf72,C. elegans | Homeostasis | Genetic screening
Journal Article
Brain Research, ISSN 0006-8993, 2016, Volume 1649, Issue Pt B, pp. 151 - 157
Abstract Charged multivesicular body protein 2B (CHMP2B) – a component of the endosomal complex required for transport-III (ESCRT-III) – is responsible for the... 
Neurology | Endolysosome | ESCRT-III | Frontotemporal dementia | Autophagy | CHMP2BIntron5 | FTD-ALS | CHMP2B | frontotemporal dementia | endolysosome
Journal Article
Neurobiology of aging, ISSN 0197-4580, 10/2013, Volume 34, Issue 10, pp. 2370 - 2378
The increased life expectancy of people living with HIV-1/AIDS is accompanied by increased prevalence of HIV-1 associated neurocognitive disorder (HAND). As... 
HIV-1 Tat | endolysosome | BACE-1 | amyloid beta
Journal Article
Traffic (Copenhagen, Denmark), ISSN 1398-9219, 6/2018, Volume 19, Issue 6, pp. 463 - 480
The Conserved Oligomeric Golgi (COG) complex controls membrane trafficking and ensures Golgi homeostasis by orchestrating retrograde vesicle trafficking within... 
GALE | endolysosome | Lamp2 | COG complex | CDG | glycosylation | Golgi | COG-CDG | MGAT1 | Cathepsin D
Journal Article
Journal of Alzheimer's disease : JAD, ISSN 1387-2877, 2019, Volume 67, Issue 1, pp. 393 - 410
Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). In furthering the understanding of mechanisms by which... 
BACE1 | TRPML1 | LDL | cholesterol | ML-SA1 | neurons | amyloid beta | endolysosome pH
Journal Article
Traffic, ISSN 1398-9219, 01/2020, Volume 21, Issue 1, pp. 60 - 75
Lysosomes are key cellular catabolic centers that also perform fundamental metabolic, signaling and quality control functions. Lysosomes are not static and... 
BORC | PIKfyve | autophagy | autolysosome | PtdIns(3,5)P2 | endolysosome | lysosomal acidification | PtdIns(4,5)P2 | lysosomal reformation | PtdInsP | fusion | V‐ATPase | lysosomal storage disorders | fission | LAMTOR | AMPK | late endosome | lysosome | Homeostasis | Lysosomes | Quality control | Review | Reviews
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 05/2017, Volume 216, Issue 5, pp. 1337 - 1355
Contacts between endosomes and the endoplasmic reticulum (ER) promote endosomal tubule fission, but the mechanisms involved and consequences of tubule fission... 
PROTEIN | STRUCTURAL BASIS | SITES | TRAFFICKING | RETROMER COMPLEX | ACCUMULATION | MUTATIONS | PATHOLOGY | ENDOLYSOSOMES | INHERITANCE | CELL BIOLOGY | Paralysis, Spastic | Physiological aspects | Tubulins | Health aspects | Endoplasmic reticulum | Protein-protein interactions
Journal Article
Journal Article