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The American journal of surgical pathology, ISSN 0147-5185, 2017, Volume 41, Issue 3, pp. 326 - 333
Mismatch repair (MMR)-deficient endometrial carcinomas (ECs) bearing Lynch syndrome (LS)-associated germline mutations or sporadic MLH1 promoter... 
PD-L1 | mismatch repair | endometrial carcinoma | MLH1 hypermethylation | immunotherapy | Lynch syndrome | SURGERY | MICROSATELLITE INSTABILITY | INFILTRATING LYMPHOCYTES | IMMUNOSCORE | PATHOLOGY | LUNG-CANCER | PROGNOSTIC-FACTOR | IMMUNE-SYSTEM | MICROENVIRONMENT | COLORECTAL-CANCER | BLOCKADE | Immunohistochemistry | Neoplastic Syndromes, Hereditary - pathology | Prognosis | Follow-Up Studies | Endometrial Neoplasms - mortality | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | Brain Neoplasms - pathology | Endometrial Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Neoplastic Syndromes, Hereditary - metabolism | Brain Neoplasms - metabolism | Neoplastic Syndromes, Hereditary - mortality | Colorectal Neoplasms, Hereditary Nonpolyposis - mortality | DNA Methylation | Endometrial Neoplasms - genetics | DNA Mismatch Repair | Biomarkers, Tumor - metabolism | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Colorectal Neoplasms - metabolism | Colorectal Neoplasms - mortality | Promoter Regions, Genetic | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Brain Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | B7-H1 Antigen - metabolism | MutL Protein Homolog 1 - genetics | Endometrial Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - pathology
Journal Article
World journal of surgery, ISSN 0364-2313, 07/2009, Volume 33, Issue 7, pp. 1502 - 1508
textabstractIntroduction: Complete resection is the most important prognostic factor in surgery for pelvic tumors. In locally advanced and recurrent pelvic... 
Medicine & Public Health | Cardiac Surgery | Surgery | Abdominal Surgery | Vascular Surgery | Thoracic Surgery | General Surgery | SURGERY | CONTINENT URINARY-DIVERSION | MORBIDITY | RESECTION | COLORECTAL-CANCER | INTRAOPERATIVE RADIOTHERAPY | EXPERIENCE | GYNECOLOGICAL MALIGNANCIES | OUTCOMES | ADVANCED RECTAL-CANCER | Endometrial Neoplasms - radiotherapy | Multivariate Analysis | Neoplasm Recurrence, Local - radiotherapy | Prognosis | Endometrial Neoplasms - mortality | Pelvic Exenteration - adverse effects | Humans | Middle Aged | Pelvic Neoplasms - mortality | Male | Uterine Cervical Neoplasms - pathology | Postoperative Complications - mortality | Neoplasm Recurrence, Local - mortality | Hospital Mortality - trends | Neoplasm Recurrence, Local - pathology | Pelvic Neoplasms - radiotherapy | Neoplasm Invasiveness - pathology | Adult | Female | Rectal Neoplasms - pathology | Retrospective Studies | Radiotherapy, Adjuvant | Pelvic Exenteration - methods | Uterine Cervical Neoplasms - mortality | Pelvic Neoplasms - pathology | Pelvic Neoplasms - surgery | Uterine Cervical Neoplasms - radiotherapy | Risk Assessment | Rectal Neoplasms - surgery | Brachytherapy - methods | Kaplan-Meier Estimate | Proportional Hazards Models | Uterine Cervical Neoplasms - surgery | Probability | Rectal Neoplasms - mortality | Rectal Neoplasms - radiotherapy | Disease-Free Survival | Endometrial Neoplasms - surgery | Survival Analysis | Quality of Life | Endometrial Neoplasms - pathology | Aged | Neoplasm Staging | Cohort Studies | Chemotherapy | Sarcoma | Health aspects | Cervical cancer | Cancer
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 09/2015, Volume 39, Issue 9, pp. 1197 - 1205
Ovarian small cell carcinoma of the hypercalcemic type (SCCOHT)/ovarian rhabdoid tumor is a rare and highly malignant tumor that typically occurs in young... 
Rhabdoid tumor | Ovary | INI1/SMARCB1 | SMARCA4/BRG1 | Small cell carcinoma hypercalcemic type | SURGERY | SMARCB1 | FUSION | NEOPLASMS | BRG1 | PATHOLOGY | small cell carcinoma hypercalcemic type | SMARCA4 | INI1 | ovary | SARCOMAS | rhabdoid tumor | MUTATIONS | Immunohistochemistry | Predictive Value of Tests | Carcinoma, Small Cell - genetics | Nuclear Proteins - analysis | Humans | Middle Aged | Ovarian Neoplasms - pathology | Sarcoma, Ewing - pathology | Granulosa Cell Tumor - pathology | Rhabdoid Tumor - pathology | Bone Neoplasms - pathology | Ovarian Neoplasms - genetics | Young Adult | Carcinoma, Small Cell - chemistry | Sarcoma, Endometrial Stromal - pathology | Soft Tissue Neoplasms - chemistry | Melanoma - genetics | Bone Neoplasms - chemistry | Adult | Female | Bone Neoplasms - genetics | Melanoma - chemistry | Soft Tissue Neoplasms - genetics | Hypercalcemia - genetics | Diagnosis, Differential | Ovarian Neoplasms - chemistry | Sarcoma, Ewing - chemistry | Hypercalcemia - pathology | Endometrial Neoplasms - chemistry | Biomarkers, Tumor - analysis | Rhabdoid Tumor - chemistry | Hypercalcemia - metabolism | Melanoma - pathology | Sarcoma, Endometrial Stromal - chemistry | Rhabdoid Tumor - genetics | Biopsy | Adolescent | Soft Tissue Neoplasms - pathology | DNA Helicases - analysis | Endometrial Neoplasms - pathology | Granulosa Cell Tumor - chemistry | Biomarkers, Tumor - genetics | Transcription Factors - analysis | Carcinoma, Small Cell - pathology | Neoplasm Staging | Sarcoma, Ewing - genetics
Journal Article
by Hendry, Shona and Salgado, Roberto and Gevaert, Thomas and Russell, Prudence A and John, Tom and Thapa, Bibhusal and Christie, Michael and van de Vijver, Koen and Estrada, M V and Gonzalez-Ericsson, Paula I and Sanders, Melinda and Solomon, Benjamin and Solinas, Cinzia and Van den Eynden, Gert G G M and Allory, Yves and Preusser, Matthias and Hainfellner, Johannes and Pruneri, Giancarlo and Vingiani, Andrea and Demaria, Sandra and Symmans, Fraser and Nuciforo, Paolo and Comerma, Laura and Thompson, E A and Lakhani, Sunil and Kim, Seong-Rim and Schnitt, Stuart and Colpaert, Cecile and Sotiriou, Christos and Scherer, Stefan J and Ignatiadis, Michail and Badve, Sunil and Pierce, Robert H and Viale, Giuseppe and Sirtaine, Nicolas and Penault-Llorca, Frederique and Sugie, Tomohagu and Fineberg, Susan and Paik, Soonmyung and Srinivasan, Ashok and Richardson, Andrea and Wang, Yihong and Chmielik, Ewa and Brock, Jane and Johnson, Douglas B and Balko, Justin and Wienert, Stephan and Bossuyt, Veerle and Michiels, Stefan and Ternes, Nils and Burchardi, Nicole and Luen, Stephen J and Savas, Peter and Klauschen, Frederick and Watson, Peter H and Nelson, Brad H and Criscitiello, Carmen and O'Toole, Sandra and Larsimont, Denis and de Wind, Roland and Curigliano, Giuseppe and André, Fabrice and Lacroix-Triki, Magali and van de Vijver, Mark and Rojo, Federico and Floris, Giuseppe and Bedri, Shahinaz and Sparano, Joseph and Rimm, David and Nielsen, Torsten and Kos, Zuzana and Hewitt, Stephen and Singh, Baljit and Farshid, Gelareh and Loibl, Sibylle and Allison, Kimberly H and Tung, Nadine and Adams, Sylvia and Willard-Gallo, Karen and Horlings, Hugo M and Gandhi, Leena and Moreira, Andre and Hirsch, Fred and Dieci, Maria V and Urbanowicz, Maria and Brcic, Iva and Korski, Konstanty and Gaire, Fabien and Koeppen, Hartmut and Lo, Amy and Giltnane, Jennifer and Rebelatto, Marlon C and Steele, Keith E and Zha, Jiping and Emancipator, Kenneth and Juco, Jonathan W and Denkert, Carsten and Reis-Filho, Jorge and Loi, Sherene and Fox, Stephen B
Advances in anatomic pathology, ISSN 1072-4109, 11/2017, Volume 24, Issue 6, pp. 311 - 335
Journal Article
Cancer chemotherapy and pharmacology, ISSN 1432-0843, 2019, Volume 84, Issue 3, pp. 487 - 499
Enzymes of the cytochrome P450 (CYP) subfamily 3A and 2C play a major role in the metabolism of taxane anticancer agents. While their function in hepatic... 
Intratumoral | Ritonavir | Paclitaxel | Docetaxel | CYP | Review | Journal Article | Medicine & Public Health | Oncology | Cancer Research | Pharmacology/Toxicology | PREGNANE-X RECEPTOR | IMMUNOHISTOCHEMICAL LOCALIZATION | DOCETAXEL RESISTANCE | CYP3A4 EXPRESSION | TARGETED THERAPIES | MESSENGER-RNA | ONCOLOGY | P450-MEDIATED METABOLISM | BIOLOGICAL-ACTIVITY | PHARMACOLOGY & PHARMACY | HIV-1 PROTEASE INHIBITOR | METABOLIZING-ENZYMES | Lung Neoplasms - drug therapy | Taxoids - pharmacology | Humans | Ovarian Neoplasms - pathology | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Male | Breast Neoplasms - enzymology | Female | Antineoplastic Agents - pharmacology | Cytochrome P-450 CYP2C8 - metabolism | Ovarian Neoplasms - drug therapy | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Endometrial Neoplasms - enzymology | Lung Neoplasms - enzymology | Neoplasms - enzymology | Breast Neoplasms - drug therapy | Ovarian Neoplasms - enzymology | Neoplasms - drug therapy | Breast Neoplasms - pathology | Cytochrome P-450 CYP3A - metabolism | Prostatic Neoplasms - enzymology | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Neoplasms - pathology | Antimitotic agents | Protease inhibitors | Proteases | Pharmacy | Cytochrome P-450 | Physiological aspects | Drugstores | Antineoplastic agents | Ovarian cancer | Cytochrome | Enzymes | Cytochrome P450 | Proteinase inhibitors | Taxane | Metabolism | Anticancer properties | Antitumor agents | Lungs | Drug metabolism | Breast | Solid tumors | Taxanes | Prostate | Endometrium | Tumors | Cytochromes P450
Journal Article
Genes and Development, ISSN 0890-9369, 06/2006, Volume 20, Issue 12, pp. 1569 - 1574
The tumor suppressor PTEN is frequently inactivated in human cancers. A major downstream effector of PTEN is Akt, which is hyperactivated via PTEN... 
Intestinal polyps | PIN | Endometrium carcinoma | Thyroid and adrenal tumors | Cancer therapy | AKT/PKB | GENETICALLY-ENGINEERED MICE | PTEN | DEVELOPMENTAL BIOLOGY | PHOSPHOINOSITIDE 3-KINASE | CANCER | CELL BIOLOGY | cancer therapy | PATHWAY | thyroid and adrenal tumors | NEOPLASIA | RELEVANCE | intestinal polyps | MUTATION | GENETICS & HEREDITY | endometrium carcinoma | Prostatic Intraepithelial Neoplasia - pathology | Thyroid Neoplasms - enzymology | Proto-Oncogene Proteins c-akt - deficiency | Male | Intestinal Polyps - enzymology | Proto-Oncogene Proteins c-akt - genetics | Adrenal Gland Neoplasms - enzymology | Prostatic Neoplasms - genetics | Endometrial Neoplasms - genetics | Neoplasms - genetics | Female | Pseudolymphoma - genetics | Pseudolymphoma - enzymology | Adrenal Gland Neoplasms - pathology | PTEN Phosphohydrolase - genetics | Prostatic Neoplasms - pathology | Endometrial Neoplasms - enzymology | Neoplasms - enzymology | PTEN Phosphohydrolase - metabolism | Pseudolymphoma - pathology | Thyroid Neoplasms - genetics | Animals | Prostatic Intraepithelial Neoplasia - enzymology | Intestinal Polyps - pathology | Prostatic Neoplasms - enzymology | Endometrial Neoplasms - pathology | Heterozygote | Mice | Prostatic Intraepithelial Neoplasia - genetics | Neoplasms - pathology | Adrenal Gland Neoplasms - genetics | Thyroid Neoplasms - pathology | Research Communication
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 1460-2105, 2016, Volume 108, Issue 6, p. djv427
Journal Article
Modern Pathology, ISSN 0893-3952, 01/2006, Volume 19, Issue 1, pp. 97 - 105
...  Modern Pathology (2006) 19, 97105 & 2006 USCAP, Inc All rights reserved 0893-3952/06 $30.00www.modernpathology.orgImmunohistochemistry for estrogen... 
Mucinous carcinoma | Estrogen receptor | Mucinous tumor | Ovary | Progesterone receptor | Metastases | mucinous carcinoma | estrogen receptor | MINIMAL DEVIATION ADENOCARCINOMA | GASTROINTESTINAL-TRACT | INTESTINAL-TYPE | mucinous tumor | PATHOLOGY | progesterone receptor | BORDERLINE TUMORS | EPITHELIAL NEOPLASMS | metastases | ovary | CELL ADENOCARCINOMA | ENDOMETRIAL ADENOCARCINOMAS | ENDOCERVICAL ADENOCARCINOMAS | DIAGNOSTIC-CRITERIA | CLINICOPATHOLOGICAL ANALYSIS | Immunohistochemistry | Pancreatic Neoplasms - metabolism | Ovary - chemistry | Humans | Ovarian Neoplasms - pathology | Stomach Neoplasms - metabolism | Stomach Neoplasms - pathology | Uterine Cervical Neoplasms - pathology | Receptors, Estrogen - analysis | Receptors, Progesterone - analysis | Ovarian Neoplasms - secondary | Uterine Cervical Neoplasms - metabolism | Gallbladder Neoplasms - metabolism | Female | Ovarian Neoplasms - metabolism | Colorectal Neoplasms - metabolism | Diagnosis, Differential | Ovary - pathology | Pancreatic Neoplasms - pathology | Adenocarcinoma, Mucinous - secondary | Appendiceal Neoplasms - metabolism | Adenocarcinoma, Mucinous - metabolism | Appendiceal Neoplasms - pathology | Gallbladder Neoplasms - pathology | Colorectal Neoplasms - pathology | Neoplasms, Unknown Primary - metabolism | Neoplasms, Unknown Primary - pathology
Journal Article
Journal Article
Cancer, ISSN 0008-543X, 2017, Volume 123, Issue 16, pp. 3080 - 3087
BACKGROUND Mirvetuximab soravtansine (IMGN853) is an antibody‐drug conjugate that selectively targets folate receptor α (FRα). In this phase 1 dose‐escalation... 
clinical trial | targeted therapy | folate receptor | phase 1 | antibody‐drug conjugate | antibody-drug conjugate | THERAPEUTICS | FARLETUZUMAB | PLATINUM-RESISTANT OVARIAN | MONOCLONAL-ANTIBODY | COMBINATION | EPITHELIAL OVARIAN-CANCER | CHEMOTHERAPY | DELIVERY | THERAPY | ONCOLOGY | PROTEINS | Lung Neoplasms - drug therapy | Humans | Middle Aged | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Fatigue - chemically induced | Diarrhea - chemically induced | Dose-Response Relationship, Drug | Vision Disorders - chemically induced | Aged, 80 and over | Immunoconjugates - therapeutic use | Adult | Female | Hypophosphatemia - chemically induced | Carcinoma, Renal Cell - drug therapy | Ovarian Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - pathology | Neoplasms, Glandular and Epithelial - pathology | Antibodies, Monoclonal, Humanized - therapeutic use | Carcinoma, Renal Cell - pathology | Maytansine - analogs & derivatives | Keratitis - chemically induced | Maytansine - therapeutic use | Disease Progression | Neoplasms - drug therapy | Maximum Tolerated Dose | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Kidney Neoplasms - pathology | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Kidney Neoplasms - drug therapy | Neoplasms - pathology | Cancer patients | Care and treatment | Pharmacokinetics | Health aspects | Analysis | Ovarian cancer | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article