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Neuropharmacology, ISSN 0028-3908, 01/2000, Volume 39, Issue 3, pp. 364 - 371
While acute activation of G sub(i/o)-coupled receptors leads to inhibition of adenylyl cyclase, chronic activation of such receptors produces an increase in... 
endomorphin
Journal Article
by Chu, XP and Xu, NS and Li, P and Wang, JQ
Neuroscience, ISSN 0306-4522, 07/1999, Volume 93, Issue 2, pp. vp - vp
The classic opioid peptide, enkephalin, and the novel member of the opioid family, nociceptin/orphanin FQ, inhibit the spontaneous electrical activity of... 
endomorphin
Journal Article
Experimental Brain Research, ISSN 0014-4819, 07/2001, Volume 139, Issue 1, pp. 70 - 75
Opiate-modulating tetrapeptides such as tyrosine-melanocyte-stimulating hormone-release inhibiting factor-1 (Tyr-MIF-1; Tyr-Pro-Leu-Gly-NH2) and Tyr-W-MIF-1... 
endomorphins
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 07/2015, Volume 288, pp. 20 - 25
Important inhibitory mechanisms for the control of water and sodium intake are present in the lateral parabrachial nucleus (LPBN). Opioid receptors are... 
Parabrachial nucleus | Sodium appetite | Endomorphin | μ Opioid receptor
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2013, Volume 110, Issue 26, pp. 10830 - 10835
mu-Opioid receptors are among the most studied G protein-coupled receptors because of the therapeutic value of agonists, such as morphine, that are used to... 
ENDOGENOUS OPIOIDS | ANTAGONIST | DAMGO | EFFICACY | MUSCARINIC RECEPTORS | MULTIDISCIPLINARY SCIENCES | analgesia | MEMBRANES | endomorphin | AGONISTS | PAIN | LIGANDS | endorphins | enkephalins | BINDING
Journal Article
ChemBioChem, ISSN 1439-4227, 08/2019, Volume 20, Issue 16, pp. 2054 - 2058
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 05/2007, Volume 73, Issue 9, pp. 1384 - 1393
The effects of endomorphin 1 (EM1) and 2 (EM2) in colonic motility remain unknown. We investigated the effects and mechanisms of these endomorphins (EMs) on... 
Colonic motility | Opioid receptors antagonists | Endomorphin 2 | Endomorphin 1 | Neural blocking agents
Journal Article
Neuroscience, ISSN 0306-4522, 09/1999, Volume 94, Issue 1, pp. 203 - 207
There appear to be different relationships between mu -opioid receptor densities and the acute and neuroadaptive mu -opioid agonist-induced responses of the... 
endomorphins
Journal Article
European Journal of Oral Sciences, ISSN 0909-8836, 10/2019, Volume 127, Issue 5, pp. 408 - 416
Endomorphin‐2 demonstrates potent antinociceptive effects in various pain models. The objectives of the present study were to explore the role of endomorphin‐2... 
opioid receptor | orofacial pain | trigeminal ganglion | orthodontic tooth movement | Periodontics | Force measurement | Pain perception | Opioid receptors | Endomorphin | Teeth | Tissues | Orthodontics | Ganglia | Pain | Naloxone | Modulation | Trigeminal ganglion
Journal Article
The Journal of Neuroscience, ISSN 0270-6474, 11/2017, Volume 37, Issue 46, p. i
Esch comments on two studies, one examines the estrus-cycle-dependent role of mGluR1 in opioid analgesia, while the other one compares fMRI, local field... 
Analgesia | Pain perception | Estrus | Endomorphin | Correlation analysis | Dynorphin | Opioids | Functional magnetic resonance imaging | Activation | Estrus cycle | Lesions | Glutamic acid receptors (metabotropic)
Journal Article
Journal of Molecular Graphics and Modelling, ISSN 1093-3263, 2010, Volume 28, Issue 6, pp. 495 - 505
Structural determinants of binding to the μ-opioid receptor, an important target in analgesia, attract great scientific attention. Many natural and synthetic... 
Molecular dynamics | Structure | μ-Opioid | Endomorphin | Peptide | Conformation
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 26, pp. 10830 - 10835
Journal Article
by Kou, ZZ and Wan, FP and Bai, Y and Li, CY and Hu, JC and Zhang, GT and Zhang, T and Chen, T and Wang, YY and Li, H and Li, YQ
FRONTIERS IN MOLECULAR NEUROSCIENCE, ISSN 1662-5099, 09/2016, Volume 9
Painful diabetic neuropathy (PDN) is one of the most common complications in the early stage of diabetes mellitus (DM). Endomorphin-2 (EM2) selectively... 
mu-opioid receptor | endomorphin 2 | spinal cord | rat | NEUROSCIENCES | painful diabetic neuropathy
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 18000 - 13
Acid-sensing ion channels (ASICs) belong to the DEG/ENaC gene family. While ASIC1a, ASIC1b and ASIC3 are activated by extracellular protons, ASIC4 and the... 
ACID | PEPTIDES | CLONING | MULTIDISCIPLINARY SCIENCES | FMRFAMIDE | SENSING ION CHANNELS | GATED NA+ CHANNEL | CURRENTS | IDENTIFICATION | ION-CHANNEL-1 | SUBUNIT | Protons | Sodium channels | Peptides | Endomorphin | Neuropeptides | Dynorphin A | Acidity | Neuromodulation | Orphan receptors | Endomorphin-1 | Dynorphin | Ligands | Ion channels
Journal Article
Frontiers in Molecular Neuroscience, ISSN 1662-5099, 09/2016, Volume 9, Issue 2016, p. 80
Painful diabetic neuropathy (PDN) is one of the most common complications in the early stage of diabetes mellitus (DM). Endomorphin-2 (EM2) selectively... 
Endomorphin 2 | Spinal cord | µ-opioid receptor | Rat | Painful diabetic neuropathy
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2009, Volume 19, Issue 18, pp. 5387 - 5391
The binding mode of a series of endomorphin analogs in μ opioid receptor is predicted. The molecular docking of a series of endomorphin analog with the μ... 
Endomorphin analogs | Molecular dynamics simulation | Molecular docking | μ Opioid receptor
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 10/2016, Volume 16, Issue 2, pp. 141 - 155
Morphine and the other alkaloids found in the opium poppy plant still represent the preferred therapeutic tools to treat severe pain in first aid protocols, as... 
Endomorphins | Opioid | Enzymatic stability | Peptidomimetic | Blood brain barrier | Lipophilicity | CHEMISTRY, MEDICINAL | PHARMACOLOGICAL CHARACTERIZATION | DRUG DISCOVERY | BLOOD-BRAIN-BARRIER | CYCLIC ENDOMORPHIN-2 | PROTEIN COUPLED RECEPTORS | BIOLOGICAL-ACTIVITY | CENTRAL-NERVOUS-SYSTEM | ENKEPHALIN ANALOGS | SOLVENT STABLE PROTEASES | BETA-PROLINE
Journal Article
BEHAVIOURAL BRAIN RESEARCH, ISSN 0166-4328, 07/2015, Volume 288, pp. 20 - 25
Important inhibitory mechanisms for the control of water and sodium intake are present in the lateral parabrachial nucleus (LPBN). Opioid receptors are... 
Endomorphin | DRINKING | NALOXONE | SALT APPETITE | ANGIOTENSIN | NEUROSCIENCES | Parabrachial nucleus | PROJECTION | NACL INTAKE | Sodium appetite | SEROTONERGIC MECHANISMS | NEURONS | BEHAVIORAL SCIENCES | mu Opioid receptor | LATERAL PARABRACHIAL NUCLEUS | WATER-INTAKE
Journal Article
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