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European Journal of Cancer, ISSN 0959-8049, 2013, Volume 50, Issue 5, pp. 987 - 996
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 2176 - 15
Microbial nucleic acid recognition serves as the major stimulus to an antiviral response, implying a requirement to limit the misrepresentation of self nucleic... 
AICARDI-GOUTIERES-SYNDROME | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVE ENZYME | MAMMALIAN DNA | MULTIDISCIPLINARY SCIENCES | ALPHA | INFLAMMATORY DISEASE | DEOXYRIBONUCLEASE-II | MUTATIONS | EXONUCLEASE TREX1 | NUCLEIC-ACIDS | Endodeoxyribonucleases - immunology | Phosphorylation | Deoxyribonucleases - deficiency | Humans | RNA, Messenger - analysis | Male | Gene Expression Profiling | Erythroblasts - immunology | Signal Transduction - immunology | Deoxyribonucleases - immunology | STAT1 Transcription Factor - metabolism | Female | Endodeoxyribonucleases - deficiency | Child | STAT3 Transcription Factor - metabolism | Interferon-alpha - metabolism | Antiviral Agents - pharmacology | Hereditary Autoinflammatory Diseases - blood | Hereditary Autoinflammatory Diseases - enzymology | Hereditary Autoinflammatory Diseases - immunology | Interferon-alpha - immunology | Up-Regulation - drug effects | Deoxyribonucleases - genetics | Hematopoiesis - immunology | Endodeoxyribonucleases - genetics | Sequence Analysis, RNA | Interferon-alpha - blood | Adolescent | Mutation | Hereditary Autoinflammatory Diseases - genetics | Glomerulonephritis | Neonates | Deformation | Liver | Antibodies | α-Interferon | Microorganisms | Lymphocytes | Hematopoiesis | Peripheral blood | Anti-DNA antibodies | Stat1 protein | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Deoxyribonuclease | Hematology | Anemia | Stat3 protein | Nucleic acids | Ribonucleic acid--RNA | Hemopoiesis | Signaling | Monocytes | Erythroblasts | Fibrosis | Interferon | Endonuclease | Life Sciences | Immunology
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 11/2014, Volume 38, Issue 11, pp. 1501 - 1509
Lynch syndrome (LS) is an autosomal dominant inherited disorder caused by germline mutations in DNA mismatch repair (MMR) genes. Mutation carriers are at... 
Microsatellite instability | Endometrial adenocarcinoma | Lynch syndrome | Mismatch-repair deficiency | SURGERY | mismatch-repair deficiency | microsatellite instability | NONPOLYPOSIS COLORECTAL-CANCER | REPAIR PROTEIN IMMUNOHISTOCHEMISTRY | RISK | GENE MUTATION | endometrial adenocarcinoma | PATHOLOGY | CLINICAL-CRITERIA | ACADEMIC-MEDICAL-CENTER | TUMOR MORPHOLOGY | GERMLINE MUTATIONS | GYNECOLOGIC CANCERS | Immunohistochemistry | MutL Protein Homolog 1 | Predictive Value of Tests | Microsatellite Instability | Biomarkers, Tumor - deficiency | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | DNA Mismatch Repair - genetics | Mass Screening - methods | DNA-Binding Proteins - deficiency | Neoplasm Grading | Endometrial Neoplasms - genetics | DNA Mutational Analysis | MutS Homolog 2 Protein - deficiency | Nuclear Proteins - deficiency | Aged, 80 and over | Adult | Female | Mismatch Repair Endonuclease PMS2 | DNA Repair Enzymes - deficiency | Adenosine Triphosphatases - deficiency | Endometrial Neoplasms - chemistry | Risk Assessment | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Risk Factors | California | Biopsy | Adaptor Proteins, Signal Transducing - deficiency | Endometrial Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - chemistry
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 6, pp. 1308 - 1316.e1
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 06/2017, Volume 23, Issue 11, pp. e32 - e37
Replication proofreading is crucial to avoid mutation accumulation in dividing cells. In humans, proofreading and replication repair is maintained by the... 
HEREDITARY | ONCOLOGY | MICROSATELLITE INSTABILITY | GERMLINE MUTATIONS | EARLY-ONSET | FOLLOW-UP | LYNCH SYNDROME | EUROPEAN CONSORTIUM CARE | CANCER | POLE | CHILDREN | Microsatellite Instability | Neoplastic Syndromes, Hereditary - pathology | Colorectal Neoplasms - genetics | Humans | Brain Neoplasms - pathology | Germ-Line Mutation - genetics | MutL Protein Homolog 1 - deficiency | Colorectal Neoplasms - diagnosis | DNA-Binding Proteins - deficiency | Neoplastic Syndromes, Hereditary - epidemiology | MutS Homolog 2 Protein - deficiency | Neoplastic Syndromes, Hereditary - genetics | Child | Mismatch Repair Endonuclease PMS2 - deficiency | Colorectal Neoplasms - epidemiology | Early Detection of Cancer | Brain Neoplasms - diagnosis | Brain Neoplasms - genetics | Neoplastic Syndromes, Hereditary - diagnosis | MutS Homolog 2 Protein - genetics | DNA-Binding Proteins - genetics | MutL Protein Homolog 1 - genetics | Colorectal Neoplasms - pathology | Mismatch Repair Endonuclease PMS2 - genetics | Brain Neoplasms - epidemiology | Yeast | MLH1 protein | Therapeutic applications | Genes | Organs | MSH2 protein | Disorders | Health risks | MSH6 protein | Exonuclease | Surveillance | Proofreading | Mismatch repair | Replication | Diagnostic systems | Mutation | Children | Genetic recombination | Repair | DNA-directed DNA polymerase | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2018, Volume 128, Issue 4, pp. 1671 - 1687
Synthetic lethality is an efficient mechanism-based approach to selectively target DNA repair defects. Excision repair cross-complementation group 1 (ERCC1)... 
NICOTINIC-ACID | MEDICINE, RESEARCH & EXPERIMENTAL | ENDONUCLEASE | METABOLISM | ERCC1 | HYPERACTIVATION | COCKAYNE-SYNDROME | PARP-1 | NAMPT INHIBITOR | DAMAGE | NUCLEOTIDE EXCISION-REPAIR
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 11/2015, Volume 52, Issue 11, pp. 770 - 778
Journal Article
Journal Article