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Analytical Chemistry, ISSN 0003-2700, 11/2003, Volume 75, Issue 21, pp. 6023 - 6028
Improved in-solution tryptic digestion of proteins in terms of speed and peptide coverage was achieved with the aid of a novel acid-labile anionic surfactant... 
MIXTURES | CHEMISTRY, ANALYTICAL | PEPTIDES | POLYACRYLAMIDE-GEL ELECTROPHORESIS | LIQUID-CHROMATOGRAPHY | SEPARATION | IDENTIFICATION | Myoglobin - metabolism | Chymotrypsin - metabolism | Ubiquitin - metabolism | Myoglobin - chemistry | Chromatography, High Pressure Liquid | Arginine - analogs & derivatives | Urea - chemistry | Neurotensin - metabolism | Ovalbumin - metabolism | Neurotensin - chemistry | Spectrometry, Mass, Electrospray Ionization | Membrane Proteins - metabolism | Molecular Structure | Ovalbumin - chemistry | Endopeptidases - metabolism | Angiotensin II - metabolism | Muramidase - chemistry | Solubility | Ubiquitin - chemistry | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods | Muramidase - metabolism | Trypsin - metabolism | Dioxolanes - chemistry | Arginine - chemistry | Angiotensin II - chemistry | Proteins - metabolism | Membrane Proteins - chemistry | Alkanesulfonates - chemistry | Sodium Dodecyl Sulfate - chemistry | Bacteriorhodopsins - metabolism | Hydrophobic and Hydrophilic Interactions | Surface-Active Agents - chemistry | Proteins - chemistry | Bacteriorhodopsins - chemistry | Arginine - metabolism | Hydrogen-Ion Concentration | Enzymes | Usage | Composition | Chemistry, Analytic | Solution (Chemistry) | Liquid chromatography | Research | Chemical compounds | Proteins | Trypsin | Surface active agents | Acids | Proteolysis | Analysis | Mass spectrometry | Scientific imaging | Index Medicus
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 12/2014, Volume 25, Issue 12, pp. 2144 - 2156
Journal Article
Science, ISSN 0036-8075, 5/2010, Volume 328, Issue 5981, pp. 1025 - 1029
SAGA is a transcriptional coactivator complex that is conserved across eukaryotes and performs multiple functions during transcriptional activation and... 
Proteins | Yeasts | Active sites | Ubiquitins | REPORTS | Histones | Atoms | Amino acids | Nucleosomes | Aldehydes | Zinc | COMPLEX | DOMAIN | UBP8 | CHROMATIN | NUCLEAR-PORE | UBIQUITIN | MULTIDISCIPLINARY SCIENCES | SUS1 | DEUBIQUITYLATION | MESSENGER-RNA EXPORT | ASSOCIATION | Transcription Factors - chemistry | Histone Acetyltransferases - chemistry | Nucleosomes - chemistry | Zinc - metabolism | Ubiquitin - metabolism | Crystallography, X-Ray | Ubiquitins - chemistry | Aldehydes - metabolism | Trans-Activators - chemistry | Zinc - chemistry | Endopeptidases - chemistry | Ubiquitination | Histone Acetyltransferases - metabolism | Ubiquitinated Proteins - metabolism | Ubiquitins - metabolism | Protein Structure, Tertiary | Endopeptidases - metabolism | Zinc Fingers | RNA-Binding Proteins - chemistry | Ubiquitin - chemistry | Models, Molecular | Nucleosomes - metabolism | Nuclear Proteins - metabolism | Nuclear Proteins - chemistry | Transcription Factors - metabolism | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein Conformation | Trans-Activators - metabolism | Histones - metabolism | RNA-Binding Proteins - metabolism | Aldehydes - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Ubiquitin | Physiological aspects | Transcription factors | Research | Eukaryotes | Biochemistry | Cellular biology | Proteases | Crystal structure | Index Medicus | Modules | Mathematical models | Assembly | Elongation
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2015, Volume 58, Issue 23, pp. 9108 - 9123
Here, we describe the most promising small synthetic organic compounds that act as potent Sortase A inhibitors and cater the potential to be developed as... 
SRTA GENE | IN-VITRO | CHEMISTRY, MEDICINAL | CELL-WALL | STREPTOCOCCUS-PNEUMONIAE | ACTIVE-SITE | STAPHYLOCOCCUS-AUREUS SORTASE | SURFACE-PROTEINS | IMIDAZOLIUM ION-PAIR | A INHIBITORS | PROTEIN ANCHORING TRANSPEPTIDASE | Aminoacyltransferases - antagonists & inhibitors | Cysteine Endopeptidases - chemistry | Small Molecule Libraries - pharmacology | Staphylococcus aureus - enzymology | Nitriles - pharmacology | Benzoates - chemistry | Humans | Bacterial Proteins - chemistry | Carbolines - chemistry | Cysteine Endopeptidases - metabolism | Rhodanine - analogs & derivatives | Rhodanine - pharmacology | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Staphylococcal Infections - microbiology | Bacterial Adhesion - drug effects | Adamantane - analogs & derivatives | Aminoacyltransferases - chemistry | Bacterial Proteins - antagonists & inhibitors | Adamantane - pharmacology | Staphylococcal Infections - drug therapy | Thiones - chemistry | Enzyme Inhibitors - pharmacology | Models, Molecular | Staphylococcus aureus - pathogenicity | Small Molecule Libraries - chemistry | Animals | Nitriles - chemistry | Benzoates - pharmacology | Aminoacyltransferases - metabolism | Bacterial Proteins - metabolism | Protein Conformation | Thiazoles - chemistry | Anti-Bacterial Agents - pharmacology | Thiazoles - pharmacology | Thiones - pharmacology | Staphylococcus aureus - drug effects | Carbolines - pharmacology | Index Medicus
Journal Article
Journal Article
ACS Nano, ISSN 1936-0851, 08/2015, Volume 9, Issue 8, pp. 8554 - 8561
Context driven biosensor assembly with modular targeting and detection moieties is gaining significant attentions. Although protein-based nanoparticles have... 
easy purification | biosensor | modularity | bionanoparticles | post-translational modification | signal amplification | DNA APTAMERS | PROTEIN | MATERIALS SCIENCE, MULTIDISCIPLINARY | ZINC-FINGER | CHEMISTRY, PHYSICAL | CELL-SURFACE | NANOSCIENCE & NANOTECHNOLOGY | SENSORS | CHEMISTRY, MULTIDISCIPLINARY | PRINCIPLES | DISPLAY | PURIFICATION | CONJUGATE | SCAFFOLDS | Cysteine Endopeptidases - chemistry | Geobacillus stearothermophilus - chemistry | Nanoparticles - chemistry | Humans | Bacterial Proteins - chemistry | Geobacillus stearothermophilus - genetics | Neoplasm Proteins - metabolism | Luciferases - chemistry | Thrombin - analysis | Neoplasm Proteins - genetics | Pyruvate Dehydrogenase Complex - metabolism | Aminoacyltransferases - chemistry | Fluorescent Dyes - chemistry | Gene Expression | Geobacillus stearothermophilus - enzymology | Mucin-1 - metabolism | Cell Separation | Aptamers, Nucleotide - chemistry | Staphylococcus aureus - chemistry | Staphylococcal Protein A - chemistry | Pyruvate Dehydrogenase Complex - chemistry | Biosensing Techniques | Bacterial Proteins - metabolism | Antibodies, Neoplasm - chemistry | Protein Processing, Post-Translational | HeLa Cells | Mucin-1 - genetics | Index Medicus | Amplification | Nanoparticles | Platforms | Modular | Biosensors | Modularity | Assembly | Decoration
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2018, Volume 57, Issue 39, pp. 12702 - 12706
Analogous to reversible post‐translational protein modifications, the ability to attach and subsequently remove modifications on proteins would be valuable for... 
Sonogashira coupling | reversible protein modification | thiol–yne | palladium-mediated cleavage | propargyl cysteine | PALLADIUM | CELLS | CLICK CHEMISTRY | ESCHERICHIA-COLI | 3C PROTEASE | thiol-yne | DEPROTECTION | CHEMISTRY, MULTIDISCIPLINARY | GENETIC-CODE | BIOCONJUGATION | TRANSFER-RNA SYNTHETASE | AMINO-ACIDS | Cysteine Endopeptidases - chemistry | Humans | Archaeal Proteins - chemistry | Green Fluorescent Proteins - genetics | Viral Proteins - metabolism | Biotin - chemistry | Cysteine Endopeptidases - metabolism | Thioredoxins - genetics | Archaeal Proteins - genetics | Thioredoxins - metabolism | Cysteine - metabolism | Catalysis | Thioredoxins - chemistry | Green Fluorescent Proteins - chemistry | Archaeal Proteins - metabolism | Green Fluorescent Proteins - metabolism | Catalytic Domain | Mutagenesis, Site-Directed | Pargyline - chemistry | Click Chemistry | Enterovirus - enzymology | Viral Proteins - chemistry | Cysteine - chemistry | Methanosarcina - metabolism | Palladium - chemistry | Cysteine | Crosslinked polymers | Thiols | Proteases | Glutathione transferase | Palladium | Cystine | Enzyme activity | Crosslinking | Biotin | Proteins | Organic chemistry | Genetic code | Enzymatic activity | Breaking | Coding | Propargyl groups | Control surfaces | Cleavage | Masking | Dimers | Chemical synthesis | Protein structure | Glutathione | Alkynes | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2009, Volume 4, Issue 9, pp. e7052 - e7052
Neurodegenerative disorders share common features comprising aggregation of misfolded proteins, failure of the ubiquitin-proteasome system, and increased... 
BIOLOGY | Protein Structure, Tertiary | Protein Structure, Secondary | Microscopy, Electron, Transmission - methods | Solvents - chemistry | Humans | Molecular Conformation | Chelating Agents - chemistry | Ubiquitin - chemistry | Ubiquitin - metabolism | Spectroscopy, Fourier Transform Infrared | Copper - chemistry | Alzheimer Disease - metabolism | Copper - metabolism | Microscopy, Atomic Force | Protein Binding | Cell Membrane - metabolism | Proteasome Endopeptidase Complex - metabolism | Electrochemistry - methods | Oligomers | Ubiquitin | Development and progression | Nervous system diseases | Analysis | Electric properties | Brain | Atomic force microscopy | Parkinson's disease | Aluminum | Disorders | Conglomerates | Sclerosis | Risk factors | Proteins | Ring structures | Particle physics | Dichroism | Chelation | Copper | Alzheimer's disease | Movement disorders | Cadmium | Dielectric constant | Trifluoroethanol | Neurodegenerative diseases | Infrared spectra | Electron microscopy | Fatty acids | Substrates | Circular dichroism | Studies | Aggregates | Proteasomes | Dismantling | Parkinsons disease | Chain branching | Lipids | Agglomeration | Infrared analysis | Protein folding | Spectrum analysis | Amyloid | Incubation | Gel electrophoresis | Health risks | Particulates | Amyotrophic lateral sclerosis | Clustering | Phosphocholine | Zinc | Coalescing | Transmission electron microscopy | N-Terminus | Nickel | Dimers | Liposomes | Alzheimers disease | Coalescence | Index Medicus
Journal Article
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 12/2015, Volume 116, pp. 42 - 49
Availability of highly purified proteins in quantity is crucial for detailed biochemical and structural investigations. Fusion tags are versatile tools to... 
Scytovirin | SUMO system | Solubility enhancement tag | TonB | Protein ligation | Fusion proteins | Ulp1 protease | SPLICING ELEMENT | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | AFFINITY TAGS | BIOCHEMICAL RESEARCH METHODS | LIGATION | IN-VITRO | MULTIDOMAIN PROTEIN | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RECOMBINANT PROTEINS | C-TERMINAL DOMAIN | INTEIN | Cyanobacteria - genetics | Cysteine Endopeptidases - chemistry | Recombinant Fusion Proteins - isolation & purification | Small Ubiquitin-Related Modifier Proteins - isolation & purification | Saccharomyces cerevisiae - genetics | Cyanobacteria - chemistry | Bacterial Proteins - chemistry | Helicobacter pylori - genetics | Lectins - isolation & purification | Small Ubiquitin-Related Modifier Proteins - genetics | Proteolysis | Base Sequence | Cloning, Molecular - methods | Carrier Proteins - chemistry | Saccharomyces cerevisiae Proteins - isolation & purification | Lectins - chemistry | Pseudomonas - genetics | Membrane Proteins - isolation & purification | Genetic Vectors - chemistry | Helicobacter pylori - chemistry | Membrane Proteins - genetics | Bacterial Proteins - genetics | Solubility | Recombinant Fusion Proteins - chemistry | Saccharomyces cerevisiae Proteins - genetics | Escherichia coli - chemistry | Genetic Vectors - genetics | Saccharomyces cerevisiae - chemistry | Carrier Proteins - genetics | Membrane Proteins - chemistry | Cysteine Endopeptidases - isolation & purification | Escherichia coli - genetics | Small Ubiquitin-Related Modifier Proteins - chemistry | Carrier Proteins - isolation & purification | Cysteine Endopeptidases - genetics | Recombinant Fusion Proteins - genetics | Lectins - genetics | Bacterial Proteins - isolation & purification | Pseudomonas - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Proteins | Antiviral agents | Sumo | Proteases | Glutathione transferase | Escherichia coli | Nuclear magnetic resonance spectroscopy | Sugars | Protein binding | Index Medicus
Journal Article
Macromolecular Bioscience, ISSN 1616-5187, 07/2018, Volume 18, Issue 7, pp. e1800095 - n/a
Herein, the synthesis of enzyme–polymer conjugates is reported. Four different activated polymers (mPEG‐aldehyde, mPEG‐NHS, maltodextrin‐aldehyde,... 
enzymes | differential scanning calorimetry (DSC) | surfactants | stabilization | modification | HALF-LIFE | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DELIVERY | STRATEGIES | PRESERVATION | NANOPARTICLES | IMMOBILIZED ENZYMES | PEGYLATION | ALPHA-AMYLASE | Detergents - chemistry | Lipase - isolation & purification | Enzymes, Immobilized - isolation & purification | Polyethylene Glycols - chemistry | Bacillus subtilis - chemistry | Alkylation | Succinimides - chemistry | Thermodynamics | Saccharomycetales - chemistry | Amination | alpha-Amylases - isolation & purification | Polysaccharides - chemistry | Carboxymethylcellulose Sodium - chemistry | Bacillus licheniformis - chemistry | Enzymes, Immobilized - chemistry | Enzyme Stability | Serine Endopeptidases - chemistry | Bacillus subtilis - enzymology | Enzyme Assays | Saccharomycetales - enzymology | Lipase - chemistry | alpha-Amylases - chemistry | Kinetics | Bacillus licheniformis - enzymology | Serine Endopeptidases - isolation & purification | Aldehydes - chemistry | Enzymes | Detergents, Synthetic | Dextrins | Polymer industry | Aldehydes | Cellulose | Carboxymethyl cellulose | Conjugates | Fractionation | Enzyme activity | Shelf life | Lipase | Detergents | Thermal stability | MPEG encoders | Organic chemistry | Chemical modification | Enzymatic activity | Maltodextrin | Video compression | Polymers | Carboxymethylcellulose | Chemical synthesis | Index Medicus
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 08/2014, Volume 62, Issue 32, pp. 8204 - 8213
Journal Article