Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2459) 2459
Newsletter (30) 30
Dissertation (27) 27
Book Chapter (21) 21
Publication (21) 21
Conference Proceeding (16) 16
Magazine Article (12) 12
Government Document (7) 7
Newspaper Article (4) 4
Reference (2) 2
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (1564) 1564
life sciences & biomedicine (1482) 1482
endostatin (1417) 1417
humans (1378) 1378
animals (1038) 1038
mice (726) 726
female (694) 694
male (648) 648
angiogenesis (620) 620
oncology (529) 529
biological and medical sciences (451) 451
endostatins (444) 444
medical sciences (397) 397
middle aged (352) 352
endostatins - genetics (337) 337
tumors (329) 329
vascular endothelial growth factor (327) 327
endostatins - metabolism (296) 296
aged (292) 292
adult (290) 290
endostatins - pharmacology (285) 285
cancer (251) 251
cell line, tumor (247) 247
biochemistry & molecular biology (241) 241
angiogenesis inhibitors - pharmacology (222) 222
endostatins - blood (219) 219
medicine, research & experimental (217) 217
research & experimental medicine (217) 217
angiogenesis inhibitors - therapeutic use (214) 214
research (203) 203
endostatins - therapeutic use (201) 201
gene therapy (196) 196
angiogenesis inhibitors (191) 191
mice, nude (180) 180
mice, inbred balb c (179) 179
cell biology (174) 174
endostatins - administration & dosage (171) 171
chemotherapy (167) 167
mice, inbred c57bl (167) 167
analysis (166) 166
care and treatment (161) 161
antineoplastic agents (160) 160
neovascularization, pathologic - drug therapy (158) 158
immunohistochemistry (156) 156
cells, cultured (155) 155
biotechnology & applied microbiology (150) 150
enzyme-linked immunosorbent assay (149) 149
antineoplastic agents - therapeutic use (147) 147
health aspects (146) 146
apoptosis (144) 144
neovascularization (141) 141
vascular endothelial growth factor a - metabolism (141) 141
rats (140) 140
pharmacology. drug treatments (139) 139
proteins (139) 139
angiostatin (135) 135
vegf (130) 130
peptide fragments - genetics (128) 128
collagen (127) 127
disease models, animal (126) 126
pharmacology & pharmacy (126) 126
genetic therapy (124) 124
recombinant human endostatin (124) 124
collagen type xviii (123) 123
gene expression (123) 123
collagen - genetics (122) 122
peptide fragments - therapeutic use (121) 121
lung cancer (120) 120
peptide fragments - pharmacology (118) 118
cardiovascular system (117) 117
neoplasm transplantation (117) 117
prognosis (115) 115
recombinant proteins - pharmacology (115) 115
antineoplastic agents - pharmacology (113) 113
neovascularization, pathologic (112) 112
physiological aspects (112) 112
cell proliferation (111) 111
collagen - therapeutic use (111) 111
blotting, western (110) 110
cell proliferation - drug effects (110) 110
tumor cells, cultured (110) 110
cell line (109) 109
genetic therapy - methods (109) 109
genetic vectors (109) 109
transfection (107) 107
metastasis (106) 106
collagen - pharmacology (103) 103
genetics & heredity (103) 103
xenograft model antitumor assays (103) 103
endothelial cells (101) 101
fundamental and applied biological sciences. psychology (99) 99
neovascularization, pathologic - pathology (99) 99
medicine (98) 98
medicine & public health (98) 98
abridged index medicus (97) 97
endostatins - biosynthesis (97) 97
vascular endothelial growth factors (97) 97
cell movement - drug effects (96) 96
angiogenesis inhibitors - genetics (95) 95
endothelium, vascular - cytology (95) 95
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2376) 2376
Chinese (256) 256
Japanese (33) 33
French (19) 19
Russian (12) 12
Portuguese (11) 11
Persian (7) 7
Polish (6) 6
Korean (5) 5
German (4) 4
Dutch (2) 2
Italian (2) 2
Turkish (2) 2
Finnish (1) 1
Slovak (1) 1
Spanish (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Effect of VEGF-C siRNA and endostatin on ring formation and proliferation of esophageal squamous cell carcinoma lymphatic endothelial cells
by Zheng, Yuping and Sun, Miaomiao and Chen, Jinyan and He, Lulu and Zhao, Na and Chen, Kuisheng
OncoTargets and therapy, ISSN 1178-6930, 10/2016, Volume 9, pp. 6727 - 6732
Ring formation | Esophageal cancer-associated lymphatic endothelial cells | VEGF-C | Proliferation | Esophageal squamous carcinoma cells | Oncology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Genetic aspects | Research | Vascular endothelial growth factor | Analysis | Esophageal cancer | Endothelium | Care and treatment | Squamous cell carcinoma | Development and progression | Gene expression | Health aspects | Diabetic retinopathy | Lymphatic system | Laboratories | Brain cancer | Metastasis | Kinases | Design | Angiogenesis | Plasmids | Fibroblasts | Diabetes | Prostate | the alive cells quantity in blank control group were the largest | Endostatin group was for the esophageal cancer cells conditional medium of optimum concentration endostatin processed | SG1 plus endostatin group and SG2 plus endostatin group. There was no statistical significance between the comparison of SG1 group and SG2 group | SG1 group | SG1 plus endostatin group and SG2 plus endostatin group (P >0.05). The comparison between rest groups had statistical significance (P | negative plus endostatin group | the three dimensional culture results of negative control group was the highest | of which were the negative plus endostatin group | SG2 group was for the conditional medium of SG2 plasmid transfected esophageal cancer cells | then followed by blank control group | endostatin group | Negative control group was for the conditional medium of empty plasmid transfected esophageal cancer cells | Objective To investigate the effects of VEGF-C inRNA eukaryotic expression vector and expression of endostatin on esophageal squamous carcinoma-related ring formation in vitro and proliferation of lymphatic endothelial cells. Methods KYSE150 cells were subjected to analysis of cell transfection and endostatin operation. The conditional medium was prepared as well. Blank control group was for the conditional medium of esophageal cancer cells without transfection | negative plus endostatin group did not have statistical significance (P>0.05) | SG1 group and negative plus endostatin group | SG1 plus endostatin group and SG2 plus endostatin group. The esophageal cancer related microlymphatic endothelial cells were three-dimensional cultured and was calculated for the various cells formed tube-like structures. CCK-8 assay was employed to detect the cell proliferation condition. Result Generally comparison | SG2 plus endostatin group. The comparsion between SG1 plus endostatin group and SG2 endostatin group did not have statistical significance (P>0.05) | SG2 group and endostation group | SG2 group and negative plus endostatin group | There were also additional three groups | SG2 group | SG1 group was for the conditional medium of SG1 plasmid transfected with esophageal cancer cells | SG1 group and endostation group | the comparison between rest groups had statistical significance (P | then followed by negative control group | the comparsion between every two of SG1 group | SG1 plus endostatin group
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Conjugation of gold nanoparticles and recombinant human endostatin modulates vascular normalization via interruption of anterior gradient 2–mediated angiogenesis
by Pan, Fan and Yang, Wende and Li, Wei and Yang, Xiao-Yan and Liu, Shuhao and Li, Xin and Zhao, Xiaoxu and Ding, Hui and Qin, Li and Pan, Yunlong
Tumor biology, ISSN 1010-4283, 7/2017, Volume 39, Issue 7, pp. 1 - 9
Angiogenesis | Vascular normalization | Recombinant human endostatin | Anterior gradient 2 | Gold nanoparticles | Life Sciences & Biomedicine | Oncology | Science & Technology | Gold - administration & dosage | Colorectal Neoplasms - genetics | Humans | Endostatins - chemistry | Neovascularization, Pathologic - pathology | Angiogenesis Inhibitors - administration & dosage | Neoplasm Metastasis | Heterografts | Colorectal Neoplasms - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Gold - chemistry | Human Umbilical Vein Endothelial Cells - drug effects | Neoplasm Proteins - biosynthesis | Metal Nanoparticles - chemistry | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Recombinant Proteins - administration & dosage | Endostatins - genetics | Proteins - genetics | Cell Movement - drug effects | Animals | Metal Nanoparticles - administration & dosage | Neovascularization, Pathologic - drug therapy | Endostatins - administration & dosage | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Mice | Colorectal Neoplasms - pathology | Angiogenesis Inhibitors - chemistry | Phosphorylation | Authorship | Colorectal carcinoma | Colorectal cancer | Endostatin | Metastasis | Cancer therapies | Metastases | Nanoparticles | Xenografts | Vascular endothelial growth factor receptor 2 | Vascular endothelial growth factor | Gold | Extracellular signal-regulated kinase | FDA approval | Cadherin | Endothelial cells | Gelatinase A | Studies | Chemotherapy | Morphology | Hypoxia | Laboratory animals | Umbilical vein | Cell migration | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Down-Regulation of Vascular Endothelial Growth Factor and Up-Regulation of Pigment Epithelium Derived Factor Make Low Molecular Weight Heparin-Endostatin and Polyethylene Glycol-Endostatin Potential Candidates for Anti-angiogenesis Drug
by Tan, Haining and Mu, Guoying and Zhu, Wei and Liu, Jinfeng and Wang, Fengshan and School of Pharmaceutical Sciences and eCollege of Life Sciences and aInstitute of Biochemical and Biotechnological Drugs and Shandong University and cSchool of Life Science and dJinan Central Hospital Affiliated to Shandong University and Clinical Medical College of Shandong University and Qufu Normal University and bNational Glycoengineering Research Center
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2011, Volume 34, Issue 4, pp. 545 - 550
low molecular weight heparin-endostatin | zebrafish | endostatin | polyethylene glycol-endostatin | choroidal neovascularization | Zebrafish | Polyethylene glycol-endostatin | Choroidal neovascularization | Low molecular weight heparin-endostatin | Endostatin | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Heparin, Low-Molecular-Weight - pharmacology | Endostatins - pharmacology | Serpins - metabolism | Endothelial Cells - metabolism | Mice, Inbred C57BL | Angiogenesis Inhibitors - pharmacology | Male | Nerve Growth Factors - metabolism | Vascular Endothelial Growth Factor A - metabolism | Heparin, Low-Molecular-Weight - therapeutic use | Polyethylene Glycols - therapeutic use | Animals | Choroidal Neovascularization - metabolism | Choroidal Neovascularization - drug therapy | Eye Proteins - metabolism | Angiogenesis Inhibitors - therapeutic use | Models, Animal | Cell Proliferation - drug effects | Mice | Endostatins - therapeutic use | Endothelial Cells - drug effects | Polyethylene Glycols - pharmacology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney
by Lin, Chi Hua Sarah and Chen, Jun and Zhang, Zhongtao and Johnson, Gail V.W and Cooper, Arthur J.L and Feola, Julianne and Bank, Alexander and Shein, Jonathan and Ruotsalainen, Heli J and Pihlajaniemi, Taina A and Goligorsky, Michael S
Kidney international, ISSN 0085-2538, 06/2016, Volume 89, Issue 6, pp. 1281 - 1292
aging kidney | collagen XVIII | fibrosis | tissue transglutaminase | endostatin | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Up-Regulation | GTP-Binding Proteins - pharmacology | Endostatins - pharmacology | Endothelial Cells | Kidney - pathology | Transglutaminases - pharmacology | Cellular Senescence - drug effects | Transglutaminases - genetics | Male | GTP-Binding Proteins - genetics | Folic Acid - toxicity | Kidney - metabolism | Extracellular Matrix Proteins | Kidney Diseases - chemically induced | Collagen Type XVIII - genetics | Collagen Type XVIII - metabolism | Kidney - drug effects | Endostatins - metabolism | Kidney Diseases - pathology | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Endostatins - genetics | Animals | Collagen Type XVIII - pharmacology | Transglutaminases - metabolism | Fibrosis | Mice | Aging - metabolism | GTP-Binding Proteins - metabolism | Index Medicus | collagen 18
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Real‐world outcomes of various regimens of recombinant human endostatin combined with chemotherapy in non‐driver gene mutation advanced non‐small cell lung cancer
by Wang, Zhongtai and Zhang, Hui and Zhou, Chunhua and Long, Xiaoyan and Guan, Rui and Yang, Nong and Zhang, Yongchang
Cancer medicine (Malden, MA), ISSN 2045-7634, 04/2019, Volume 8, Issue 4, pp. 1434 - 1441
real‐world study | different administration | chemotherapy | recombinant human‐endostatin | non‐small cell lung cancer | non-small cell lung cancer | real-world study | recombinant human-endostatin | Life Sciences & Biomedicine | Oncology | Science & Technology | Recombinant Proteins - therapeutic use | Lung Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Platinum - therapeutic use | Drug Administration Schedule | Humans | Male | Treatment Outcome | Platinum - administration & dosage | Recombinant Proteins - administration & dosage | Propensity Score | Endostatins - administration & dosage | Survival Analysis | Female | Carcinoma, Non-Small-Cell Lung - drug therapy | Endostatins - therapeutic use | Medical research | Chemotherapy | Gene mutations | Analysis | Genes | Genetic research | Medicine, Experimental | Lung cancer, Small cell | Genetic aspects | Lung cancer, Non-small cell | Cancer | Cell survival | Lung cancer | Endostatin | Non-small cell lung carcinoma | Metastasis | FDA approval | Patients | Cancer therapies | Disease control | Studies | Pathology | Vomiting | Platinum | Consent | Point mutation | Mutation | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension
by Damico, Rachel and Kolb, Todd M and Valera, Lidenys and Wang, Lan and Housten, Traci and Tedford, Ryan J and Kass, David A and Rafaels, Nicholas and Gao, Li and Barnes, Kathleen C and Benza, Raymond L and Rand, James L and Hamid, Rizwan and Loyd, James E and Robbins, Ivan M and Hemnes, Anna R and Chung, Wendy K and Austin, Eric D and Drummond, M. Bradley and Mathai, Stephen C and Hassoun, Paul M
American journal of respiratory and critical care medicine, ISSN 1073-449X, 01/2015, Volume 191, Issue 2, pp. 208 - 218
Collagen 18a1 | Genetics | Pulmonary arterial hypertension | Survival | Endostatin | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Severity of Illness Index | Hypertension, Pulmonary - mortality | Predictive Value of Tests | Hypertension, Pulmonary - classification | Prognosis | Follow-Up Studies | Humans | Middle Aged | Kaplan-Meier Estimate | Proportional Hazards Models | Hypertension, Pulmonary - genetics | Male | Collagen Type XVIII - blood | Biomarkers - blood | Hypertension, Pulmonary - blood | Endostatins - genetics | Exercise Test | Collagen Type XVIII - genetics | Endostatins - blood | Female | ROC Curve | Ventricular Dysfunction, Right - physiopathology | Polymorphism, Single Nucleotide | Index Medicus | Abridged Index Medicus | collagen 18a1 | genetics | endostatin | Original | pulmonary arterial hypertension | survival
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The effect of intracellular protein delivery on the anti-tumor activity of recombinant human endostatin
by Lim, Junghee and Duong, Tam and Lee, Guewha and Seong, Baik Lin and El-Rifai, Wael and Ruley, H. Earl and Jo, Daewoong
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 26, pp. 6261 - 6271
Advanced Basic Science | Dentistry | Macromolecule transduction domain | Intracellular delivery | Protein therapy | Endostatin | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Human Umbilical Vein Endothelial Cells | NIH 3T3 Cells | Humans | Recombinant Fusion Proteins - therapeutic use | Molecular Sequence Data | Antineoplastic Agents - therapeutic use | Endostatins - chemistry | Antineoplastic Agents - metabolism | Angiogenesis Inhibitors - therapeutic use | Antineoplastic Agents - pharmacokinetics | Endostatins - therapeutic use | Protein Structure, Tertiary | Amino Acid Sequence | Angiogenesis Inhibitors - genetics | Neoplasms - blood supply | Angiogenesis Inhibitors - pharmacokinetics | Recombinant Fusion Proteins - chemistry | Antineoplastic Agents - chemistry | Neoplasms - drug therapy | Endostatins - genetics | Animals | Recombinant Fusion Proteins - pharmacokinetics | Recombinant Fusion Proteins - genetics | Mice | Mice, Inbred BALB C | Neoplasms - pathology | Endostatins - pharmacokinetics | Angiogenesis Inhibitors - chemistry | Medical colleges | Angiogenesis inhibitors | Vascular endothelial growth factor | Collagen | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Phase II Study of Recombinant Human Endostatin in Patients With Advanced Neuroendocrine Tumors
by Matthew H. Kulke and Emily K. Bergsland and David P. Ryan and Peter C. Enzinger and Thomas J. Lynch and Andrew X. Zhu and Jeffrey A. Meyerhardt and John V. Heymach and William E. Fogler and Carolyn Sidor and Ann Michelini and Kate Kinsella and Alan P. Venook and Charles S. Fuchs
Journal of clinical oncology, ISSN 0732-183X, 08/2006, Volume 24, Issue 22, pp. 3555 - 3561
Biological and medical sciences | Medical sciences | Tumors | Recombinant Proteins - therapeutic use | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Angiogenesis Inhibitors - blood | Angiogenesis Inhibitors - administration & dosage | Self Administration | Antineoplastic Agents - adverse effects | Injections, Subcutaneous | Aged, 80 and over | Angiogenesis Inhibitors - therapeutic use | Adult | Female | Endostatins - adverse effects | Angiogenesis Inhibitors - adverse effects | Endostatins - therapeutic use | Carcinoma, Neuroendocrine - blood | Carcinoma, Neuroendocrine - drug therapy | Treatment Outcome | Disease-Free Survival | Carcinoma, Neuroendocrine - pathology | Endostatins - administration & dosage | Survival Analysis | Antineoplastic Agents - blood | Endostatins - blood | Aged | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Characterization, bioactivity and pharmacokinetic study of a novel carbohydrate-peptide polymer: Glycol-split heparin-endostatin2 (GSHP-ES2)
by Sun, Feng and Wang, Zhendong and Yang, Zhifang and Li, Yan and Cui, Huifei and Liu, Chunhui and Gao, Dezong and Wang, Fengshan and Tan, Haining
Carbohydrate polymers, ISSN 0144-8617, 03/2019, Volume 207, pp. 79 - 90
Stability | Anti-angiogenesis | ES2 | Zebra fish | Glycol-split heparin | Physical Sciences | Chemistry | Chemistry, Organic | Polymer Science | Chemistry, Applied | Science & Technology | Endostatins - toxicity | Endostatins - pharmacology | Humans | Half-Life | Female | Glycopeptides - pharmacokinetics | Angiogenesis Inhibitors - chemical synthesis | Cell Line | Oligopeptides - chemical synthesis | Glycopeptides - toxicity | Endostatins - chemical synthesis | Drug Stability | Oligopeptides - pharmacokinetics | Angiogenesis Inhibitors - pharmacology | Zebrafish | Angiogenesis Inhibitors - pharmacokinetics | Oligopeptides - toxicity | Cell Movement - drug effects | Glycopeptides - chemical synthesis | Animals | Angiogenesis Inhibitors - toxicity | Chickens | Mice, Inbred BALB C | Glycopeptides - pharmacology | Oligopeptides - pharmacology | Endostatins - pharmacokinetics | Heparin - chemistry | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Fibroblasts in fibrosis: Novel roles and mediators
by Kendall, Ryan T and Feghali-Bostwick, Carol A
Frontiers in pharmacology, ISSN 1663-9812, 2014, Volume 5, pp. 123 - 123
fibroblast | endostatin | myofibroblast | scleroderma | fibrosis | idiopathic pulmonary fibrosis | extracellular matrix | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Idiopathic Pulmonary Fibrosis | Extracellular Matrix | Fibrosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights