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1. Full Text Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
by Xu, Wei and Yang, Hui and Liu, Ying and Yang, Ying and Wang, Ping and Kim, Se-Hee and Ito, Shinsuke and Yang, Chen and Wang, Pu and Xiao, Meng-Tao and Liu, Li-xia and Jiang, Wen-qing and Liu, Jing and Zhang, Jin-ye and Wang, Bin and Frye, Stephen and Zhang, Yi and Xu, Yan-hui and Lei, Qun-ying and Guan, Kun-Liang and Zhao, Shi-min and Xiong, Yue
Cancer cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 17 - 30
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism | Index Medicus
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2. Full Text Cathepsin S Controls Angiogenesis and Tumor Growth via Matrix-derived Angiogenic Factors
by Bing Wang and Jiusong Sun and Shiro Kitamoto and Min Yang and Anders Grubb and Harold A. Chapman and Raghu Kalluri and Guo-Ping Shi
The Journal of biological chemistry, ISSN 0021-9258, 03/2006, Volume 281, Issue 9, pp. 6020 - 6029
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neoplasms - metabolism | Autoantigens - metabolism | Cell Proliferation | Pancreatic Neoplasms - metabolism | Humans | Neovascularization, Pathologic | Extracellular Matrix - metabolism | Recombinant Fusion Proteins - metabolism | Extracellular Matrix - chemistry | Angiogenesis Inducing Agents - metabolism | Cystatin C | Collagen Type IV - metabolism | Peptide Fragments - metabolism | Endostatins - metabolism | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Mice, Transgenic | Protease Inhibitors - metabolism | Survival Rate | Cystatins - metabolism | Cell Adhesion Molecules - metabolism | Mice, Knockout | Angiogenesis Inhibitors - metabolism | Animals | Cathepsins - genetics | Cystatins - genetics | Cathepsins - metabolism | Recombinant Fusion Proteins - genetics | Mice | Neoplasms - pathology | Index Medicus | Medicinal Chemistry | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology | Läkemedelskemi
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3. Full Text IL-32 promotes angiogenesis
by Nold-Petry, C.A and Rudloff, I and Baumer, Y and Ruvo, M and Marasco, D and Botti, P and Farkas, L and Cho, S.X and Zepp, J.A and Azam, T and Dinkel, H and Palmer, B.E and Boisvert, W.A and Cool, C.D and Taraseviciene-Stewart, L and Heinhuis, B and Joosten, L.A and Dinarello, C.A and Voelkel, N.F and Nold, M.F
The Journal of immunology (1950), ISSN 0022-1767, 2014, Volume 192, Issue 2, pp. 589 - 602
Life Sciences & Biomedicine | Immunology | Science & Technology | Human Umbilical Vein Endothelial Cells | Humans | Transforming Growth Factor beta1 - metabolism | Activins - metabolism | Vascular Endothelial Growth Factor A - metabolism | Glioblastoma - embryology | Interferon-gamma - metabolism | Integrin alphaVbeta3 - metabolism | Interleukins - metabolism | Neovascularization, Pathologic - pathology | Matrix Metalloproteinase 9 - metabolism | Receptors, Vascular Endothelial Growth Factor - metabolism | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Interleukin-8 - metabolism | Nitrogen Oxides - metabolism | Endostatins - metabolism | Cells, Cultured | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary - metabolism | Animals | Glioblastoma - pathology | Mice | Neovascularization, Pathologic - metabolism | Apoptosis - physiology | Hypertension, Pulmonary - pathology | Index Medicus | Abridged Index Medicus
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4. Full Text Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia
by Utpal Sen and Pushpakumar B. Sathnur and Sourav Kundu and Srikanth Givvimani and Denise M. Coley and Paras K. Mishra and Natia Qipshidze and Neetu Tyagi and Naira Metreveli and Suresh C. Tyagi
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 07/2012, Volume 303, Issue 1, pp. 41 - 51
Hydrogen sulfide | Cystathionine γ-lyase | Cystathionine β-synthase | 3-mercaptopyruvate sulfurtransferase | Mitophagy | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Hydrogen Sulfide - metabolism | Genetic Therapy | Vascular Endothelial Growth Factor A - biosynthesis | Reactive Oxygen Species - metabolism | Hyperhomocysteinemia - therapy | Hyperhomocysteinemia - metabolism | Cystathionine gamma-Lyase - metabolism | Homocysteine - metabolism | Hypertension, Renovascular - genetics | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Forkhead Transcription Factors - metabolism | Renal Artery - metabolism | Cystathionine gamma-Lyase - genetics | Cystathionine beta-Synthase - genetics | Proto-Oncogene Proteins c-akt - metabolism | Organ Culture Techniques | Endostatins - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Sulfurtransferases - genetics | Hypertension, Renovascular - therapy | Cystathionine beta-Synthase - metabolism | Matrix Metalloproteinase 13 - metabolism | Animals | Hyperhomocysteinemia - genetics | Mice | Forkhead Box Protein O3 | Platelet Endothelial Cell Adhesion Molecule-1 - biosynthesis | Vascular System Injuries | Sulfurtransferases - metabolism | Index Medicus | homocysteine | cystathionine γ-lyase | mitophagy | hydrogen sulfide | cystathionine β-synthase
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5. Full Text Angiogenesis in chronic liver disease and its complications
by Coulon, Stephanie and Heindryckx, Femke and Geerts, Anja and Van Steenkiste, Christophe and Colle, Isabelle and Van Vlierberghe, Hans
Liver international, ISSN 1478-3223, 02/2011, Volume 31, Issue 2, pp. 146 - 162
chronic liver diseases | non‐alcoholic steatohepatitis | portal hypertension | angiogenesis | hepatocellular carcinoma | Angiogenesis | Chronic liver diseases | Hepatocellular carcinoma | Non-alcoholic steatohepatitis | Portal hypertension | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Microvessels - physiopathology | Hypertension, Portal - physiopathology | Cadherins - metabolism | Hypertension, Portal - complications | Humans | Fatty Liver - complications | Liver Neoplasms - complications | Vascular Endothelial Growth Factor A - metabolism | Hypoxia-Inducible Factor 1 - metabolism | Integrins - metabolism | Neovascularization, Pathologic - etiology | Fibroblast Growth Factors - metabolism | Carcinoma, Hepatocellular - drug therapy | Receptors, Vascular Endothelial Growth Factor - metabolism | Carcinoma, Hepatocellular - complications | Liver Neoplasms - physiopathology | Non-alcoholic Fatty Liver Disease | Angiogenesis Inhibitors - therapeutic use | Neovascularization, Pathologic - physiopathology | Angiostatins - metabolism | Angiopoietins - metabolism | Carcinoma, Hepatocellular - physiopathology | Endostatins - metabolism | Liver Cirrhosis - complications | Fatty Liver - physiopathology | Liver Neoplasms - drug therapy | Disease Progression | Platelet-Derived Growth Factor - metabolism | Models, Biological | Signal Transduction - physiology | Liver Cirrhosis - physiopathology | Chronic Disease | Thrombospondins - metabolism | Hypertension | Complications and side effects | Liver cancer | Development and progression | Mortality | Index Medicus
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6. Full Text Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli
by Chatterjee, Madhumita and Huang, Zhangsen and Zhang, Wei and Jiang, Lei and Hultenby, Kjell and Zhu, Linjing and Hu, Hu and Nilsson, Gunnar P and Li, Nailin
Blood, ISSN 0006-4971, 04/2011, Volume 117, Issue 14, pp. 3907 - 3911
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Medical sciences | Membrane Glycoproteins - metabolism | Endostatins - metabolism | Humans | Middle Aged | Receptor, PAR-1 - agonists | Platelet Activation - physiology | Male | Vascular Endothelial Growth Factor A - metabolism | Blood Platelets - secretion | Angiogenesis Inhibitors - metabolism | Carrier Proteins - metabolism | Chemokine CXCL12 - metabolism | Peptides - metabolism | Blood Platelets - metabolism | Angiogenesis Inducing Agents - metabolism | Platelet Membrane Glycoproteins - metabolism | Fluorescent Antibody Technique | Adult | Female | Platelet Activation - drug effects | Blood Platelets - drug effects | In Vitro Techniques | Oligopeptides - pharmacology | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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7. Full Text Expression of angiogenesis-related factors in human corneas after cultivated oral mucosal epithelial transplantation
by Chen, Hung-Chi Jesse and Yeh, Lung-Kun and Tsai, Yueh-Ju and Lai, Chyong-Huey and Chen, Chi-Chun and Lai, Jui-Yang and Sun, Chi-Chin and Chang, Grace and Hwang, Tsann-Long and Chen, Jan-Kan and Ma, David Hui-Kang
Investigative ophthalmology & visual science, ISSN 0146-0404, 08/2012, Volume 53, Issue 9, pp. 5615 - 5623
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Cornea - surgery | Postoperative Complications - etiology | Burns, Chemical - metabolism | Humans | Middle Aged | Postoperative Complications - metabolism | Male | Mouth Mucosa - transplantation | Transplantation, Autologous | Nerve Growth Factors - metabolism | Vascular Endothelial Growth Factor A - metabolism | Eye Burns - pathology | Cornea - blood supply | Interleukin 1 Receptor Antagonist Protein - metabolism | Fibroblast Growth Factor 2 - metabolism | Adult | Retrospective Studies | Corneal Neovascularization - etiology | Postoperative Complications - pathology | Serpins - metabolism | Endostatins - metabolism | Tissue Culture Techniques | Eye Burns - surgery | Treatment Outcome | Burns, Chemical - surgery | Epithelium - transplantation | Cornea - metabolism | Corneal Neovascularization - metabolism | Eye Proteins - metabolism | Adolescent | Burns, Chemical - pathology | Eye Burns - metabolism | Signal Transduction - physiology | Corneal Neovascularization - pathology | Clinical Trials, Phase I as Topic | Index Medicus
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8. Full Text Endostatin Is a Trans-Synaptic Signal for Homeostatic Synaptic Plasticity
by Wang, Tingting and Hauswirth, Anna G and Tong, Amy and Dickman, Dion K and Davis, Graeme W
Neuron (Cambridge, Mass.), ISSN 0896-6273, 08/2014, Volume 83, Issue 3, pp. 616 - 629
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Calcium Channels - metabolism | Calcium - metabolism | Endostatins - metabolism | Humans | Chondroitin Sulfate Proteoglycans - metabolism | Neurotransmitter Agents - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - metabolism | Collagen - metabolism | Animals | Neuronal Plasticity - physiology | Synapses - metabolism | Homeostasis - physiology | Signal Transduction - physiology | Calcium channels | Angiogenesis inhibitors | Collagen | Analysis | Index Medicus | Epilepsy | Endostatin | Schizophrenia | Calcium channel | Neuromuscular junction | CaV2.1 | Autism | Neuron | Synaptic transmission | Retrograde signaling | Extracellular matrix | Homeostatic plasticity | Synaptic homeostasis | Multiplexin
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9. Full Text Generation and degradation of human endostatin proteins by various proteinases
by Ferreras, Mercedes and Felbor, Ute and