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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 10/2015, Volume 112, Issue 40, pp. 12516 - 12521
Human pluripotent stem cell-based in vitro models that reflect human physiology have the potential to reduce the number of drug failures in clinical trials and offer a cost-effective approach... 
Organoid | Toxicology | Differentiation | Tissue engineering | Machine learning | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Embryonic Stem Cells - metabolism | Microglia - metabolism | Embryonic Stem Cells - cytology | Humans | Brain - growth & development | Support Vector Machine | Neural Stem Cells - cytology | Xenobiotics - pharmacology | Brain - metabolism | Neurogenesis - genetics | Mesenchymal Stromal Cells - cytology | Xenobiotics - classification | Gene Expression Regulation, Developmental | Cell Differentiation | Neurogenesis - drug effects | Culture Media, Serum-Free - pharmacology | Gene Ontology | Polyethylene Glycols - pharmacology | Microglia - cytology | Mesenchymal Stromal Cells - drug effects | Brain - cytology | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Microglia - drug effects | Endothelial Cells - metabolism | Cells, Cultured | Neural Stem Cells - drug effects | Mesenchymal Stromal Cells - metabolism | Cell Communication - genetics | Macrophages - cytology | Pluripotent Stem Cells - metabolism | Macrophages - metabolism | Embryonic Stem Cells - drug effects | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Cell Communication - drug effects | Macrophages - drug effects | Hydrogels - pharmacology | Neural Stem Cells - metabolism | Endothelial Cells - drug effects | Index Medicus | toxicology | Biological Sciences | tissue engineering | differentiation | machine learning | organoid
Journal Article
PloS one, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, pp. e46436 - e46436
Mesenchymal cells arise from the neural crest (NC) or mesoderm. However, it is difficult to distinguish NC-derived cells from mesoderm-derived cells... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | Chondrocytes - cytology | Adipocytes - cytology | Wnt1 Protein - metabolism | Adipocytes - drug effects | Mesoderm - cytology | Osteoclasts - cytology | Cell Lineage - drug effects | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Tooth - cytology | Bone Marrow Cells - drug effects | Integrases - metabolism | Colony-Forming Units Assay | Osteoblasts - cytology | B-Lymphocytes - metabolism | Chondrocytes - metabolism | Lymphopoiesis - drug effects | Mesenchymal Stromal Cells - drug effects | B-Lymphocytes - cytology | Neural Crest - cytology | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Osteoblasts - drug effects | Thymus Gland - cytology | Mesenchymal Stromal Cells - metabolism | Mice, Transgenic | Osteoclasts - metabolism | Antibodies - pharmacology | B-Lymphocytes - drug effects | Animals | Cell Differentiation - drug effects | Receptors, Platelet-Derived Growth Factor - metabolism | Adipocytes - metabolism | Bacterial Proteins - metabolism | Mice | Osteoblasts - metabolism | Bone Marrow Cells - metabolism | Osteoclasts - drug effects | Luminescent Proteins - metabolism | Cysteine | Genetic engineering | Platelet-derived growth factor | B cells | Analysis | Stem cells | Mesenchyme | Interleukin | Mesoderm | Stem cell transplantation | Adipocytes | Tissues | Thymus | Stem cell factor | Interleukin 7 | Signal transduction | Biomedical materials | Allografts | Lymphocytes | Coding | Rodents | Bone marrow | Biocompatibility | Growth factors | University graduates | Medical research | Origins | Developmental biology | Colonies | Fetuses | Teeth | Transgenic mice | Gene expression | Neural crest | Endothelial cells | Hemopoiesis | Medicine | Studies | Osteoclastogenesis | Lymphocytes B | Osteoclasts | Dental pulp | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 2/2014, Volume 111, Issue 5, pp. 1915 - 1920
IL-15 is a cytokine critical for development, maintenance, and response of T cells, natural killer (NK... 
T lymphocytes | Spleen | Lymphocytes | Natural killer T cells | Stromal cells | Antibodies | Bone marrow | Inflammation | Lymph nodes | Research universities | Aging | Homeostasis | Differentiation | Thymus | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Inflammation - pathology | Mesoderm - drug effects | Mesoderm - cytology | Aging - immunology | Mucous Membrane - cytology | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Stromal Cells - drug effects | Bone Marrow Cells - drug effects | Lymph Nodes - drug effects | Mucous Membrane - drug effects | Thymus Gland - metabolism | Lymphoid Tissue - drug effects | Spleen - growth & development | Bone Marrow Cells - cytology | Endothelial Cells - metabolism | Stromal Cells - metabolism | Thymus Gland - cytology | Lymph Nodes - metabolism | Lymphoid Tissue - metabolism | Spleen - cytology | Thymus Gland - drug effects | Lymph Nodes - cytology | Gene Knock-In Techniques | Mucous Membrane - metabolism | Lymphoid Tissue - cytology | Animals | Spleen - metabolism | T-Lymphocytes - cytology | Endothelial Cells - cytology | Interleukin-15 - metabolism | Lipopolysaccharides - pharmacology | Mice | Bone Marrow Cells - metabolism | Stromal Cells - cytology | Endothelial Cells - drug effects | Physiological aspects | Interleukin-15 | Research | Health aspects | Immunological research | Index Medicus | Biological Sciences | homeostasis | thymus | differentiation | aging
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 01/2019, Volume 565, Issue 7740, pp. 505 - 510
.... Diabetes also impairs the functions of endothelial cells5 and disturbs the communication between endothelial cells and pericytes6... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Blood Vessels - growth & development | Basement Membrane - drug effects | Pericytes - drug effects | Blood Vessels - pathology | Humans | Pericytes - cytology | Hyperglycemia - complications | Venules - drug effects | Organoids - transplantation | Arteries - cytology | Basement Membrane - pathology | Intercellular Signaling Peptides and Proteins - metabolism | Diabetic Angiopathies - pathology | Inflammation Mediators - pharmacology | Diabetic Angiopathies - enzymology | Arterioles - cytology | Receptor, Notch3 - metabolism | Organoids - pathology | Pluripotent Stem Cells - cytology | Signal Transduction | Basement Membrane - cytology | Organoids - cytology | Arteries - drug effects | Venules - cytology | Arterioles - drug effects | Blood Vessels - cytology | Amyloid Precursor Protein Secretases - metabolism | Animals | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Blood Vessels - drug effects | Organoids - drug effects | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | In Vitro Techniques | Endothelial Cells - drug effects | Type 2 diabetes | Blood vessels | Research | Diabetes | Heart | Diabetic retinopathy | Epidemics | Regulators | Nuclear magnetic resonance--NMR | Transplants & implants | Arterioles | Stem cell transplantation | Blood | Arteries | Angiogenesis | Hyperglycemia | Vascular diseases | Organoids | Amputation | Heart diseases | Thickening | Stroke | Cytokines | Diabetes mellitus | Inflammation | Gene expression | Patients | Endothelial cells | Endothelium | Collagen | Blindness | Stem cells | Renal failure | Pericytes | Microvasculature | Pluripotency | Structure-function relationships | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 05/2018, Volume 9, Issue 1, pp. 1828 - 14
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 10/2018, Volume 9, Issue 1, pp. 4383 - 21
Journal Article