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The Oncologist, ISSN 1083-7159, 06/2015, Volume 20, Issue 6, pp. 660 - 673
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 09/2010, Volume 29, Issue 36, pp. 4989 - 5005
Hepatocellular carcinoma (HCC) is a highly prevalent, treatment-resistant malignancy with a multifaceted molecular pathogenesis. Current evidence indicates... 
Signaling | Hepatocellular carcinoma | Multikinase inhibitor | Vascular endothelial growth factor | Sorafenib | Epidermal growth factor receptor | FACTOR-RECEPTOR | signaling | sorafenib | MESSENGER-RNA EXPRESSION | epidermal growth factor receptor | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MET PROTOONCOGENE | CELL BIOLOGY | CELL LUNG-CANCER | PHASE-II TRIAL | ONCOLOGY | vascular endothelial growth factor | GENETICS & HEREDITY | TYROSINE KINASE INHIBITOR | PROGNOSTIC-SIGNIFICANCE | ACTIVATED PROTEIN-KINASES | multikinase inhibitor | TUMOR-GROWTH | hepatocellular carcinoma | ENDOTHELIAL GROWTH-FACTOR | Receptor, Epidermal Growth Factor - genetics | Receptors, Vascular Endothelial Growth Factor - physiology | MAP Kinase Signaling System - physiology | Humans | Liver Neoplasms - therapy | Liver Neoplasms - etiology | Somatomedins - physiology | Hepatocyte Growth Factor - physiology | Carcinoma, Hepatocellular - genetics | Hepatocyte Growth Factor - genetics | Liver Neoplasms - pathology | Carcinoma, Hepatocellular - etiology | Receptors, Vascular Endothelial Growth Factor - genetics | Receptor, Epidermal Growth Factor - physiology | Liver Neoplasms - genetics | Signal Transduction - genetics | Proto-Oncogene Proteins c-met - genetics | Liver Neoplasms - ethnology | Proto-Oncogene Proteins c-met - physiology | Animals | Models, Biological | Somatomedins - genetics | Carcinoma, Hepatocellular - pathology | Signal Transduction - physiology | Carcinoma, Hepatocellular - therapy | Care and treatment | Gene mutations | Cellular signal transduction | Genetic aspects | Research | Hepatoma | Health aspects | Signal transduction | Genetics | Liver diseases | Mutation | Cancer
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2002, Volume 316, Issue 3, pp. 769 - 787
Vascular endothelial growth factor (VEGF) is a potent endothelial cell-specific mediator of angiogenesis and vasculogenesis. VEGF is involved pathologically in... 
protein structure | NMR | angiogenesis | vascular endothelial growth factor | peptide antagonist | Angiogenesis | Peptide antagonist | Protein structure | Vascular endothelial growth factor | MOLECULAR-DYNAMICS | TRIPLE-RESONANCE EXPERIMENTS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN-STRUCTURE DETERMINATION | RECEPTOR-BINDING DOMAIN | BIOACTIVE CONFORMATION | ANGSTROM RESOLUTION | DE-NOVO DESIGN | IMPROVED SENSITIVITY | INTERPROTON DISTANCE RESTRAINTS | Disulfides - metabolism | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor A | Endothelial Growth Factors - metabolism | Vascular Endothelial Growth Factors | Humans | Molecular Sequence Data | Receptors, Growth Factor - antagonists & inhibitors | Crystallography, X-Ray | Endothelial Growth Factors - chemistry | Proto-Oncogene Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-1 | Lymphokines - genetics | Peptides - chemical synthesis | Peptides - metabolism | Alanine - genetics | Solutions | Lymphokines - antagonists & inhibitors | Protein Structure, Quaternary | Lymphokines - metabolism | Nuclear Magnetic Resonance, Biomolecular | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Binding Sites | Dimerization | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Proto-Oncogene Proteins - antagonists & inhibitors | Bacteriophages - chemistry | Peptides - chemistry | Protein Structure, Secondary | Models, Molecular | Alanine - metabolism | Mutation - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Receptors, Growth Factor - chemistry | Peptides - pharmacology | Endothelial Growth Factors - antagonists & inhibitors | Lymphokines - chemistry | Endothelial Growth Factors - genetics | Hydrophobic and Hydrophilic Interactions | Receptor Protein-Tyrosine Kinases - chemistry | Receptors, Growth Factor - metabolism
Journal Article
Genes and Development, ISSN 0890-9369, 05/2008, Volume 22, Issue 10, pp. 1276 - 1312
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as prototypes for growth factor and receptor tyrosine kinase function for more... 
Development | PDGF receptor | Platelet-derived growth factor | Fibrosis | Cancer | development | platelet-derived growth factor | DEVELOPMENTAL BIOLOGY | FACTOR-B-CHAIN | FACTOR-RECEPTOR-BETA | CELL BIOLOGY | SIMIAN SARCOMA-VIRUS | GENETICS & HEREDITY | PDGF-ALPHA-RECEPTOR | FACTOR-A-CHAIN | TYROSINE KINASE INHIBITOR | cancer | fibrosis | SMOOTH-MUSCLE-CELLS | IDIOPATHIC HYPEREOSINOPHILIC SYNDROME | HEPARAN-SULFATE PROTEOGLYCANS | GASTROINTESTINAL STROMAL TUMORS | Receptors, Vascular Endothelial Growth Factor - physiology | Genetic Predisposition to Disease | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Embryo, Mammalian | Humans | Embryonic Development - genetics | Receptors, Platelet-Derived Growth Factor - genetics | Receptors, Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - genetics | Platelet-Derived Growth Factor - genetics | Organogenesis | Disease - etiology | Tissue Distribution | Platelet-Derived Growth Factor - metabolism | Animals | Models, Biological | Signal Transduction - physiology | Polymorphism, Single Nucleotide | Receptors, Vascular Endothelial Growth Factor - genetics | Bone and Bones - embryology | Nervous System - embryology | Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - physiology | Cardiovascular System - embryology | Tyrosine | Hematopoiesis | Pharmacology | Research | Chemical properties | Phosphotransferases | Health aspects | Review
Journal Article