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Journal Article
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2002, Volume 316, Issue 3, pp. 769 - 787
Vascular endothelial growth factor (VEGF) is a potent endothelial cell-specific mediator of angiogenesis and vasculogenesis. VEGF is involved pathologically in... 
protein structure | NMR | angiogenesis | vascular endothelial growth factor | peptide antagonist | Angiogenesis | Peptide antagonist | Protein structure | Vascular endothelial growth factor | MOLECULAR-DYNAMICS | TRIPLE-RESONANCE EXPERIMENTS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN-STRUCTURE DETERMINATION | RECEPTOR-BINDING DOMAIN | BIOACTIVE CONFORMATION | ANGSTROM RESOLUTION | DE-NOVO DESIGN | IMPROVED SENSITIVITY | INTERPROTON DISTANCE RESTRAINTS | Disulfides - metabolism | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor A | Endothelial Growth Factors - metabolism | Vascular Endothelial Growth Factors | Humans | Molecular Sequence Data | Receptors, Growth Factor - antagonists & inhibitors | Crystallography, X-Ray | Endothelial Growth Factors - chemistry | Proto-Oncogene Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-1 | Lymphokines - genetics | Peptides - chemical synthesis | Peptides - metabolism | Alanine - genetics | Solutions | Lymphokines - antagonists & inhibitors | Protein Structure, Quaternary | Lymphokines - metabolism | Nuclear Magnetic Resonance, Biomolecular | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Binding Sites | Dimerization | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Proto-Oncogene Proteins - antagonists & inhibitors | Bacteriophages - chemistry | Peptides - chemistry | Protein Structure, Secondary | Models, Molecular | Alanine - metabolism | Mutation - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Receptors, Growth Factor - chemistry | Peptides - pharmacology | Endothelial Growth Factors - antagonists & inhibitors | Lymphokines - chemistry | Endothelial Growth Factors - genetics | Hydrophobic and Hydrophilic Interactions | Receptor Protein-Tyrosine Kinases - chemistry | Receptors, Growth Factor - metabolism | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 38, pp. 10028 - 10042
Abstract The regeneration capacity of the osteoporotic bones is generally lower than that of the normal bones. Current methods of bone defect treatment for... 
Advanced Basic Science | Dentistry | Osteoclastogenesis | Bioceramics | Angiogenesis | Osteogenesis | ERK/p38 signaling pathways | Strontium-substituted calcium silicate | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | PROMOTES OSTEOGENIC DIFFERENTIATION | HYDROXYAPATITE | APATITE | OVARIECTOMIZED RATS | MESENCHYMAL STEM-CELLS | KINASE PATHWAYS | RANELATE | IN-VIVO | MARROW STROMAL CELLS | Bone Regeneration - physiology | Endothelial Growth Factors - metabolism | Humans | Rats, Inbred F344 | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Silicates - chemistry | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Female | Flavonoids - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Real-Time Polymerase Chain Reaction | Calcium Compounds - chemistry | Bone Regeneration - drug effects | Cell Line | Rats | p38 Mitogen-Activated Protein Kinases - genetics | Imidazoles - pharmacology | Strontium - chemistry | Blotting, Western | Animals | Ceramics - chemistry | Endothelial Growth Factors - genetics | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Pyridines - pharmacology | Strontium | Osteoporosis | Biological products | Analysis | Stem cells | Ceramics | Vascular endothelial growth factor | Ceramic materials | Phosphotransferases | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, pp. e33418 - e33418
Switching to a glycolytic metabolism is a rapid adaptation of tumor cells to hypoxia. Although this metabolic conversion may primarily represent a rescue... 
OXYGEN | AUTOCRINE LOOP | METABOLISM | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | AEROBIC GLYCOLYSIS | GENE-EXPRESSION | GROWTH-FACTOR | HIF-1-ALPHA | CANCER | HYPOXIA-INDUCIBLE FACTOR-1 | Immunohistochemistry | RNA, Small Interfering - genetics | Enzyme-Linked Immunosorbent Assay | Endothelial Cells - metabolism | Humans | Lactic Acid - metabolism | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Neoplasms - blood supply | Hypoxia-Inducible Factor 1 - metabolism | Blotting, Western | Cell Movement - physiology | Symporters - metabolism | Fibroblast Growth Factors - metabolism | Monocarboxylic Acid Transporters - metabolism | Animals | Analysis of Variance | RNA Interference | Luciferases | Polymerase Chain Reaction | Nuclear Magnetic Resonance, Biomolecular | Mice | Neovascularization, Pathologic - metabolism | Lactic Acid - pharmacology | Endothelial Cells - physiology | Physiological aspects | Fibroblast growth factors | Vascular endothelial growth factor | Tumors | Endothelium | Fibroblast growth factor | Hypoxia-inducible factor 1 | Nuclear magnetic resonance--NMR | Leukocyte migration | Activation | Angiogenesis | Rodents | Oxidation | Inhibition | Vascular endothelial growth factor receptor 2 | Hypoxia-inducible factors | Fibroblast growth factor 2 | Tumor cells | Metabolism | Endothelial cells | Microscopy | Nitric oxide | Glycolysis | Hypoxia | Lactic acid | Transporter | Cell migration | Cancer | Index Medicus | Nuclear magnetic resonance | NMR
Journal Article
Journal Article