X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (5638) 5638
Book Review (1090) 1090
Publication (492) 492
Newsletter (167) 167
Book Chapter (35) 35
Conference Proceeding (16) 16
Newspaper Article (11) 11
Book / eBook (10) 10
Dissertation (8) 8
Magazine Article (3) 3
Transcript (2) 2
Data Set (1) 1
Paper (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (4739) 4739
animals (3252) 3252
endothelin (2822) 2822
male (2570) 2570
humans (2249) 2249
rats (1914) 1914
endothelin receptor antagonists (1508) 1508
pharmacology & pharmacy (1258) 1258
female (1222) 1222
hypertension (947) 947
rats, sprague-dawley (823) 823
endothelin-1 (808) 808
physiology (685) 685
cardiac & cardiovascular systems (683) 683
blood pressure - drug effects (667) 667
pulmonary hypertension (634) 634
bosentan (612) 612
expression (594) 594
nitric oxide (588) 588
endothelin-1 - metabolism (571) 571
middle aged (563) 563
dose-response relationship, drug (551) 551
hypertension, pulmonary - drug therapy (542) 542
cells (519) 519
nitric-oxide (512) 512
rats, wistar (511) 511
abridged index medicus (508) 508
peripheral vascular disease (486) 486
adult (480) 480
endothelin a receptor antagonists (480) 480
disease models, animal (479) 479
research (479) 479
mice (460) 460
endothelin-1 - pharmacology (456) 456
receptor, endothelin a (432) 432
endothelin receptor antagonist (431) 431
peptides, cyclic - pharmacology (417) 417
sulfonamides - pharmacology (389) 389
endothelins - pharmacology (385) 385
physiological aspects (373) 373
vasoconstriction - drug effects (373) 373
rat (371) 371
rodents (369) 369
treatment outcome (369) 369
endothelium (365) 365
respiratory system (364) 364
time factors (364) 364
blood pressure (346) 346
aged (338) 338
analysis (338) 338
blood-pressure (336) 336
endothelin-1 - physiology (330) 330
vasoconstriction (330) 330
receptors, endothelin - metabolism (327) 327
care and treatment (324) 324
antihypertensive agents - therapeutic use (319) 319
hemodynamics - drug effects (316) 316
hypertension, pulmonary - physiopathology (315) 315
neurosciences (315) 315
receptor, endothelin a - metabolism (312) 312
receptor (309) 309
sulfonamides - therapeutic use (309) 309
pulmonary arterial hypertension (305) 305
receptors (300) 300
endothelins - physiology (299) 299
endothelin-1 - blood (295) 295
antagonist (293) 293
drug therapy (293) 293
receptor antagonist (292) 292
in vitro techniques (291) 291
medicine & public health (290) 290
endothelins - metabolism (282) 282
nitric-oxide synthase (281) 281
medicine, research & experimental (280) 280
oligopeptides - pharmacology (276) 276
receptors, endothelin - physiology (275) 275
urology & nephrology (273) 273
therapy (268) 268
health aspects (267) 267
hemodynamics (259) 259
antihypertensive agents - pharmacology (258) 258
inhibition (253) 253
disease (252) 252
receptor, endothelin b (250) 250
surgery (247) 247
endothelin 1 (238) 238
sulfonamides - administration & dosage (238) 238
hypertension - physiopathology (237) 237
ischemia (237) 237
biochemistry & molecular biology (233) 233
cells, cultured (231) 231
oxidative stress (229) 229
heart failure (226) 226
double-blind (225) 225
enzyme inhibitors - pharmacology (224) 224
administration, oral (220) 220
angiotensin-ii (215) 215
inflammation (215) 215
in-vivo (211) 211
antihypertensive agents - administration & dosage (209) 209
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (5760) 5760
German (25) 25
French (24) 24
Japanese (13) 13
Russian (10) 10
Spanish (6) 6
Chinese (5) 5
Korean (3) 3
Polish (3) 3
Hungarian (2) 2
Danish (1) 1
Latvian (1) 1
Norwegian (1) 1
Persian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Circulation, ISSN 0009-7322, 12/2014, Volume 130, Issue 23, pp. 2021 - 2030
Journal Article
European Heart Journal, ISSN 0195-668X, 04/2017, Volume 38, Issue 15, pp. 1147 - 1155
Journal Article
The Oncologist, ISSN 1083-7159, 10/2015, Volume 20, Issue 10, pp. 1121 - 1122
Journal Article
Circulation, ISSN 0009-7322, 09/2010, Volume 122, Issue 10, pp. 958 - 966
Background-Endothelin (ET-1) is one of the most potent vasoconstrictors and plays a seminal role in the pathogenesis of atherosclerosis. The present study was... 
coronary disease | endothelin | endothelium | blood flow | CONTROLLED-TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | EXPERIMENTAL HYPERCHOLESTEROLEMIA | ENDOGENOUS ENDOTHELIN | FLOW VELOCITY | REFRACTORY PROSTATE-CANCER | MESSENGER-RNA | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | ESSENTIAL-HYPERTENSION | EX-VIVO | HEMATOLOGY | HUMAN ARTERIES | Endothelin-1 - antagonists & inhibitors | Follow-Up Studies | Humans | Middle Aged | Pyrrolidines - administration & dosage | Pyrrolidines - adverse effects | Endothelium, Vascular - drug effects | Male | Microcirculation - drug effects | Enzyme Inhibitors - administration & dosage | Heart Rate - drug effects | Adult | Female | Blood Pressure - drug effects | Uric Acid - blood | Lipoprotein(a) - blood | Kidney - drug effects | Coronary Artery Disease - metabolism | Coronary Artery Disease - drug therapy | Blood Glucose - drug effects | omega-N-Methylarginine - administration & dosage | Endothelium, Vascular - metabolism | Triglycerides - blood | Receptor, Endothelin A - metabolism | Coronary Circulation - drug effects | Nitric Oxide - metabolism | Antagonists (Biochemistry) | Endothelin | Patient outcomes | Atherosclerosis | Dosage and administration | Drug therapy | Health aspects | Index Medicus | Abridged Index Medicus | endothelium independent coronary flow reserve | endothelin-1 (ET-1) | coronary artery diameter | Atrasentan | endothelium dependent coronary blood flow
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 11/2014, Volume 64, Issue 5, pp. 473 - 480
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 05/2017, Volume 323, pp. 53 - 65
Sacubitril/valsartan (LCZ696) is the first angiotensin receptor neprilysin inhibitor approved to reduce cardiovascular mortality and hospitalization in... 
SILK-Aβ | Angiotensin receptor neprilysin inhibitor | Sacubitril/valsartan | LCZ696 | Amyloid beta | Alzheimer's disease | LOCALIZATION | A-BETA-42 | ALZHEIMERS-DISEASE | HEART-FAILURE | ENDOPEPTIDASE-24.11 | ENKEPHALINASE | IDENTIFICATION | SILK-A beta | PHARMACOLOGY & PHARMACY | CHOROID-PLEXUS | TOXICOLOGY | BRAIN | Immunohistochemistry | Up-Regulation | Angiotensin Receptor Antagonists - pharmacokinetics | Protease Inhibitors - pharmacokinetics | Humans | Brain - enzymology | Macaca fascicularis | Aminobutyrates - toxicity | Aminobutyrates - pharmacokinetics | Tetrazoles - administration & dosage | Biotransformation | Protease Inhibitors - toxicity | Amyloid beta-Peptides - metabolism | Angiotensin Receptor Antagonists - toxicity | Isotope Labeling | Protease Inhibitors - administration & dosage | Female | Aminobutyrates - administration & dosage | Recombinant Proteins - metabolism | Risk Assessment | Administration, Oral | Neprilysin - metabolism | Brain - drug effects | Animals | Protein Isoforms | Neprilysin - antagonists & inhibitors | Tetrazoles - toxicity | Tetrazoles - pharmacokinetics | Angiotensin Receptor Antagonists - administration & dosage | Index Medicus | CLEARANCE | CEREBROSPINAL FLUID | STABLE ISOTOPES | 60 APPLIED LIFE SCIENCES | ANGIOTENSIN | CONCENTRATION RATIO | ABUNDANCE | HEART | PARAFFIN | FLUORESCENCE | ENZYMES | ENDOTHELINS | MONKEYS | RECEPTORS | FORMALDEHYDE
Journal Article
Journal Article
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 11/2014, Volume 78, Issue 5, pp. 1035 - 1042
AimTo study the mutual pharmacokinetic interactions between macitentan, an endothelin receptor antagonist, and sildenafil in healthy male subjects. MethodsIn... 
pharmacokinetics | endothelin receptor antagonist | healthy subjects | macitentan | sildenafil | drug−drug interaction | Healthy subjects | Macitentan | Sildenafil | Drug-drug interaction | Endothelin receptor antagonist | Pharmacokinetics | CLINICAL-PHARMACOLOGY | MECHANISM | PULMONARY ARTERIAL-HYPERTENSION | SAFETY | COMBINATION THERAPY | INDUCTION | INHIBITION | CITRATE | PHARMACOLOGY & PHARMACY | drug-drug interaction | BOSENTAN | CYCLOSPORINE | Piperazines - administration & dosage | Endothelin Receptor Antagonists - pharmacokinetics | Endothelin Receptor Antagonists - administration & dosage | Area Under Curve | Pyrimidines - blood | Humans | Middle Aged | Substrate Specificity | Male | Metabolic Clearance Rate | Purines - administration & dosage | Healthy Volunteers | Phosphodiesterase 5 Inhibitors - pharmacokinetics | Sildenafil Citrate | Young Adult | Sulfonamides - blood | Drug Interactions | Purines - blood | Adult | Piperazines - pharmacokinetics | Phosphodiesterase 5 Inhibitors - pharmacology | Piperazines - blood | Phosphodiesterase 5 Inhibitors - blood | Drug Administration Schedule | Administration, Oral | Purines - pharmacology | Pyrimidines - administration & dosage | Purines - pharmacokinetics | Phosphodiesterase 5 Inhibitors - administration & dosage | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Piperazines - pharmacology | Sulfonamides - pharmacokinetics | Cross-Over Studies | Endothelin Receptor Antagonists - pharmacology | Cytochrome P-450 CYP3A - metabolism | Adolescent | Endothelin Receptor Antagonists - blood | Pyrimidines - pharmacokinetics | Sulfonamides - administration & dosage | Metabolites | Drug interactions | Analysis | Investigations | Index Medicus
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 08/2017, Volume 9, Issue 8, pp. 1011 - 1029
Journal Article
Journal Article
by Heerspink, Hiddo J L and Parving, Hans-Henrik and Andress, Dennis L and Bakris, George and Correa-Rotter, Ricardo and Hou, Fan-Fan and Hou, Fanfan and Kitzman, Dalane W and Kohan, Donald and Makino, Shinya and Makino, Hirofumi and McMurray, John J V and Melnick, Joel Z and Miller, Michael G and Miller, Alan and Miller, Steven and Pergola, Pablo E and Pergola, Pablo and Perkovic, Vlado and Tobe, Sheldon and Yi, Joo Hark and Yi, Tingting and Wigderson, Melissa and de Zeeuw, Dick and Elbert, Alicia and Vallejos, Augusto and Alvarisqueta, Andres and Maffei, Laura and Juncos, Luis and de Arteaga, Javier and Greloni, Gustavo and Farias, Eduardo and Zucchini, Alfredo and Vogel, Daniel and Cusumano, Ana and Santos, Juan and Fraenkel, Margaret and Gallagher, Martin and Davis, Tim and Acharya, Shamasunder and Cooke, Duncan and Suranyi, Michael and Roger, Simon and Toussaint, Nigel and Pollock, Carol and Chan, Doris and Stranks, Stephen and MacIsaac, Richard and Endre, Zoltan and Schmidt, Alice and Schmidt, Rebecca and Prager, Rudolf and Mayer, Gert and Warling, Xavier and Jadoul, Michel and Hougardy, Jean and Vercammen, Chris and Van Vlem, Bruno and Gillard, Pieter and Costa e Forti, Adriana and Borges, Joao Lindolfo and Santos Canani, Luis and Eliaschewitz, Freddy and Leite, Silmara and Fraige Filho, Fadlo and Paschoalin, Raphael and Moura Neto, Jose Andrade and Deboni, Luciane and de Lourdes Noronha, Irene and Cercato, Cintia and Prompt, Carlos Alberto and Zanella, Maria and Rassi, Nelson and D'Avila, Domingos and Milagres, Rosangela and Felicio, Joao and Pecoits Filho, Roberto and Riella, Miguel Carlos and Salles, Joao and Keitel, Elizete and Draibe, Sergio and Amodeo, Celso and Youmbissi, Joseph and Roy, Louise and Cournoyer, Serge and Jolly, Shivinder and Pichette, Vincent and Nesrallah, Gihad and Bajaj, Harpreet Singh and Khandwala, Hasnain and Aronson, Ronnie and Goluch, Richard and Tam, Paul and Rabbat, Christian and Bailey, Gordon and Chow, Stephen and Castillo, Alvaro and Danin Vargas, Alfredo and Gonzalez, Fernando and Munoz, Rodrigo and ... and SONAR Comm Investigators and SONAR Committees and Investigators
The Lancet, ISSN 0140-6736, 05/2019, Volume 393, Issue 10184, pp. 1937 - 1947
Short-term treatment for people with type 2 diabetes using a low dose of the selective endothelin A receptor antagonist atrasentan reduces albuminuria without... 
MEDICINE, GENERAL & INTERNAL | INHIBITION | ENDOTHELIN | ALBUMINURIA | NEPHROPATHY | Humans | Middle Aged | Male | Diabetic Nephropathies - blood | Serum Albumin, Human - urine | Young Adult | Aged, 80 and over | Adult | Female | Diabetic Nephropathies - prevention & control | Endothelin A Receptor Antagonists - therapeutic use | Diabetic Nephropathies - urine | Glomerular Filtration Rate | Double-Blind Method | Endothelin A Receptor Antagonists - administration & dosage | Administration, Oral | Treatment Outcome | Creatinine - urine | Renal Insufficiency, Chronic - blood | Renal Insufficiency, Chronic - prevention & control | Atrasentan - therapeutic use | Creatinine - blood | Aged | Atrasentan - administration & dosage | Diabetes Mellitus, Type 2 - drug therapy | Renal Insufficiency, Chronic - urine | Short term | Enrichment | End-stage renal disease | Renal function | Endothelin | Heart attacks | Peptides | Clinical trials | Cardiovascular disease | Transplantation | Retention | Randomization | Renin | Motivation | Hemoglobin | Blood pressure | Safety | Diabetes mellitus (non-insulin dependent) | Heart diseases | Drug dosages | Heart failure | Urine | Creatinine | Enzymes | Kidneys | Epidermal growth factor receptors | Anemia | Diabetes mellitus | Health risks | Patients | Disease control | Glomerular filtration rate | Sodium | Angiotensin | Renal failure | Dialysis | Kidney diseases | Diabetes | Surface area | Potassium | Kidney transplantation | Long-term effects | Index Medicus | Abridged Index Medicus
Journal Article