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PloS one, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47662 - e47662
Two endothelin receptor antagonists (ERAs), bosentan and ambrisentan, are currently approved for the treatment of pulmonary arterial hypertension (PAH... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cricetinae | Endothelin-1 - metabolism | Humans | Receptors, Endothelin - metabolism | Familial Primary Pulmonary Hypertension | Calcium - analysis | Hypertension, Pulmonary - metabolism | Pulmonary Artery - drug effects | Pyridazines - pharmacology | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Pulmonary Artery - cytology | Inositol Phosphates - analysis | Phenylpropionates - pharmacology | Clinical Trials, Phase III as Topic | Pulmonary Artery - metabolism | Animals | Hypertension, Pulmonary - drug therapy | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Endothelin Receptor Antagonists | CHO Cells | Endothelin | Physiological aspects | Smooth muscle | Genetic aspects | Research | Drug therapy | Pulmonary hypertension | Membrane proteins | Cell proliferation | Phosphates | Calcium | Assaying | Contraction | Cell growth | Rodents | Dissociation | Hypertension | Incubation | Pulmonary arteries | Washout | Muscles | Pharmacology | Endothelin 1 | Gene expression | Muscle contraction | Morbidity | Calcium phosphates | In vivo methods and tests | Kinetics | Receptor mechanisms | Aberration | Prolongation | Pharmaceuticals | Veins & arteries | Index Medicus
Journal Article
Pharmacological reviews, ISSN 1521-0081, 04/2016, Volume 68, Issue 2, pp. 357 - 418
.... Highly selective peptide ETA and ETB antagonists and ETB agonists together with radiolabeled analogs have accurately delineated endothelin pharmacology in humans and animal models, although... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Receptors, Endothelin - chemistry | Endothelin Receptor Antagonists - pharmacology | Animals | Receptors, Endothelin - agonists | Humans | Receptors, Endothelin - metabolism | Endothelins - metabolism | Endothelin Receptor Antagonists - classification | Index Medicus | Review
Journal Article