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Chest, ISSN 0012-3692, 2012, Volume 141, Issue 1, pp. 20 - 26
Journal Article
Lancet neurology, ISSN 1474-4422, 2011, Volume 10, Issue 7, pp. 618 - 625
Journal Article
American journal of respiratory and critical care medicine, ISSN 1535-4970, 2005, Volume 171, Issue 11, pp. 1292 - 1297
Journal Article
Journal of pharmacy and pharmacology, ISSN 0022-3573, 04/2013, Volume 65, Issue 4, pp. 465 - 473
...) signalling related to the transactivation of cell surface protein kinase receptors and the therapeutic implications. Key findings... 
GPCR | protein serine/threonine kinases | protein tyrosine kinases | transactivation | protein serine | PROTEOGLYCAN SYNTHESIS | EGF-RECEPTOR | PHOSPHORYLATION | ANGIOTENSIN-II | VASCULAR SMOOTH-MUSCLE | threonine kinases | SIGNAL-TRANSDUCTION | BLOCKERS | GROWTH-FACTOR RECEPTOR | PHARMACOLOGY & PHARMACY | SMAD | TGF-BETA ACTIVATION | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Receptors, Endothelin - agonists | Cardiovascular Diseases - drug therapy | Humans | Thrombin - antagonists & inhibitors | Receptor-Interacting Protein Serine-Threonine Kinases - chemistry | Endothelins - metabolism | Molecular Targeted Therapy | Receptors, Cell Surface - antagonists & inhibitors | Receptors, Thrombin - antagonists & inhibitors | Receptors, Thrombin - agonists | Drug Design | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Receptor Protein-Tyrosine Kinases - agonists | Endothelin Receptor Antagonists | Endothelins - antagonists & inhibitors | Cardiovascular Diseases - metabolism | Receptors, Cell Surface - agonists | Receptors, Endothelin - metabolism | Receptors, Cell Surface - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Cardiovascular Agents - pharmacology | Cardiovascular Agents - therapeutic use | Animals | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Receptors, Thrombin - metabolism | Protein Kinase Inhibitors - pharmacology | Thrombin - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Tyrosine | Medical colleges | Glycosaminoglycans | Drugstores | Thrombin | Transforming growth factors | Analysis | Atherosclerosis | Physiological aspects | Phenols | G proteins | Health aspects | Phosphotransferases
Journal Article
Journal Article
Journal Article
Journal Article
Expert Opinion on Drug Metabolism & Toxicology, ISSN 1744-7607, 2015, Volume 11, Issue 3, pp. 437 - 449
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 7, p. e102009
.... This study examined the effects of ETB antagonists on brain edema formation and disruption of the blood-brain barrier in a mouse cold injury model... 
STROKE | ACTIVATION | MULTIDISCIPLINARY SCIENCES | CEREBRAL-ARTERY OCCLUSION | MATRIX-METALLOPROTEINASE-9 | ISCHEMIA | GROWTH-FACTOR | BARRIER BREAKDOWN | ASTROCYTES | EXPRESSION | AGONIST | Glial Fibrillary Acidic Protein - genetics | Receptors, Endothelin - genetics | Male | Brain Injuries - physiopathology | Endothelins - metabolism | Glial Fibrillary Acidic Protein - metabolism | Biphenyl Compounds - therapeutic use | Oligopeptides - therapeutic use | Brain Edema - prevention & control | Cerebrum - metabolism | Real-Time Polymerase Chain Reaction | Cerebrum - drug effects | Dipeptides - therapeutic use | Brain Edema - etiology | RNA, Messenger - genetics | Receptors, Endothelin - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blood-Brain Barrier - drug effects | Blotting, Western | Cold Temperature - adverse effects | Azepines - therapeutic use | Brain Injuries - prevention & control | Endothelins - genetics | Receptors, Endothelin - chemistry | Animals | Brain Edema - physiopathology | Piperidines - therapeutic use | Cerebrum - injuries | Indoles - therapeutic use | Mice | Brain Injuries - etiology | Endothelin Receptor Antagonists - therapeutic use | Traumatic brain injury | Laboratories | Pathogenesis | mRNA | Head injuries | Blood-brain barrier | Ischemia | Moisture content | Extravasation | Rodents | Cerebrum | Water content | Attenuation | Vascular endothelial growth factor | Injuries | Edema | Stroke | Cold | Astrocytes | Glial fibrillary acidic protein | Cortex | Albumin | Pharmacology | Endothelin 1 | Permeability | Gene expression | Trauma | Pharmacy | Brain damage | Veins & arteries
Journal Article