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PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47662 - e47662
Two endothelin receptor antagonists (ERAs), bosentan and ambrisentan, are currently approved for the treatment of pulmonary arterial hypertension (PAH), a... 
PATHWAYS | GENE | MULTIDISCIPLINARY SCIENCES | SHEAR-STRESS | IN-VIVO | CALCIUM | DEGRADATION | PROLIFERATION | MECHANISMS | HYPERTENSION | EXPRESSION | Cricetinae | Endothelin-1 - metabolism | Humans | Receptors, Endothelin - metabolism | Familial Primary Pulmonary Hypertension | Calcium - analysis | Hypertension, Pulmonary - metabolism | Pulmonary Artery - drug effects | Pyridazines - pharmacology | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Pulmonary Artery - cytology | Inositol Phosphates - analysis | Phenylpropionates - pharmacology | Clinical Trials, Phase III as Topic | Pulmonary Artery - metabolism | Animals | Hypertension, Pulmonary - drug therapy | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Endothelin Receptor Antagonists | CHO Cells | Endothelin | Physiological aspects | Smooth muscle | Genetic aspects | Research | Drug therapy | Pulmonary hypertension | Membrane proteins | Cell proliferation | Phosphates | Calcium | Assaying | Contraction | Cell growth | Rodents | Hypertension | Incubation | Pulmonary arteries | Muscles | Radioactive half-life | Pharmacology | Endothelin 1 | Gene expression | Muscle contraction | Morbidity | Calcium phosphates | In vivo methods and tests | Kinetics | Receptor mechanisms | Aberration | Prolongation | Pharmaceuticals | Veins & arteries | Index Medicus
Journal Article
Nature Reviews Nephrology, ISSN 1759-5061, 2019, Volume 15, Issue 8, pp. 461 - 462
The SONAR trial reports that treatment with the selective endothelin A receptor antagonist atrasentan reduced the risk of renal events in patients with... 
UROLOGY & NEPHROLOGY | Endothelin | Kidney diseases | Research | Hypertension | Clinical trials | Inflammation | Retention | Design | Pain | Sodium | Nitric oxide | Blood pressure | Diabetes | Sickle cell disease | Prostate cancer | Drug dosages
Journal Article
Journal Article
Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9699, pp. 1423 - 1431
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2005, Volume 171, Issue 11, pp. 1292 - 1297
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2015, Volume 352, Issue 2, pp. 281 - 290
Journal Article
Journal Article
Chest, ISSN 0012-3692, 2013, Volume 144, Issue 3, pp. 952 - 958
Journal Article
Chest, ISSN 0012-3692, 2012, Volume 141, Issue 1, pp. 20 - 26
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2006, Volume 47, Issue 10, pp. 2049 - 2056
Journal Article
Journal Article
Experimental Eye Research, ISSN 0014-4835, 11/2018, Volume 176, pp. 1 - 9
Hypertension is an independent risk factor for diabetic retinopathy, yet anti-hypertensive medications such as blockade of angiotensin II do not completely... 
Hypertension | Diabetic retinopathy | Endothelin | VEGF | Diabetes | Vascular leakage | Retinal pigment epithelium | CELLS | ACTIVATION | ANGIOGENESIS | PREVALENCE | MODEL | DISEASE | OPHTHALMOLOGY | GROWTH-FACTOR | EXPRESSION | PROGRESSION | RETINAL-PIGMENT EPITHELIUM | Retinal Pigment Epithelium - metabolism | Retina - metabolism | Intravitreal Injections | Streptozocin | Rats, Inbred WKY | Ocular Hypertension - metabolism | Blood-Retinal Barrier - drug effects | Oligopeptides - therapeutic use | Ocular Hypertension - prevention & control | Endothelin A Receptor Antagonists - metabolism | Diabetes Mellitus, Experimental - prevention & control | Endothelin-2 - genetics | Blood Pressure - drug effects | Endothelin-2 - metabolism | Real-Time Polymerase Chain Reaction | Endothelin A Receptor Antagonists - therapeutic use | Fluorescent Antibody Technique, Indirect | Rats, Inbred SHR | Endothelin B Receptor Antagonists - therapeutic use | Choroid - metabolism | Enzyme-Linked Immunosorbent Assay | Endothelin-1 - genetics | Endothelin-1 - metabolism | Rats | Endothelin B Receptor Antagonists - metabolism | Antihypertensive Agents - therapeutic use | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - prevention & control | Animals | Piperidines - therapeutic use | Peptides, Cyclic - therapeutic use | Endothelial growth factors | RNA | Angiotensin | Endothelium | Index Medicus
Journal Article