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American journal of physiology: Gastrointestinal and liver physiology, ISSN 1522-1547, 07/2009, Volume 297, Issue 1, pp. G27 - G33
Endothelin-1 (ET-1), a potent vasoactive peptide, plays an important role in the pathogenesis of liver disease and portal hypertension. Two major endothelin... 
In vivo microscopy | Cirrhosis | Endothelial cell | Endothelin B receptor | Mixed endothelin receptor antagonist | Fibrosis | Stellate cell | Portal pressure | Endothelin A receptor | Gastroenterology & Hepatology | Physiology | Life Sciences & Biomedicine | Science & Technology | Liver - pathology | Hypertension, Portal - physiopathology | Pyrrolidines - administration & dosage | Male | Endothelins - metabolism | Liver Cirrhosis, Experimental - physiopathology | Hypertension, Portal - chemically induced | Hypertension, Portal - prevention & control | Pyrrolidines - pharmacology | Portal Pressure - drug effects | Liver Cirrhosis, Experimental - prevention & control | Liver - drug effects | Time Factors | Liver Circulation - drug effects | Endothelin A Receptor Antagonists | Liver - metabolism | Mice, Inbred C57BL | Endothelin B Receptor Antagonists | Sulfonamides - pharmacology | Vasoconstriction - drug effects | Liver - blood supply | Animals | Hypertension, Portal - metabolism | Liver Cirrhosis, Experimental - chemically induced | Receptor, Endothelin A - metabolism | Mice | Receptor, Endothelin B - metabolism | Infusions, Intravenous | Vasodilation - drug effects | Liver Cirrhosis, Experimental - metabolism | Sulfonamides - administration & dosage | Hypertension | Liver diseases | Rodents | Liver | Hepatology | Index Medicus | endothelin B receptor | endothelial cell | in vivo microscopy | portal pressure | fibrosis | stellate cell | Liver and Biliary Tract | endothelin A receptor | cirrhosis | mixed endothelin receptor antagonist
Journal Article
American journal of physiology. Lung cellular and molecular physiology, ISSN 1040-0605, 12/2011, Volume 301, Issue 6, pp. L881 - L891
Journal Article
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 08/2009, Volume 297, Issue 2, pp. 337 - 351
Increasing efferent renal sympathetic nerve activity (ERSNA) increases afferent renal nerve activity (ARNA), which in turn decreases ERSNA via activation of... 
Substance P | Renal pelvis | Sensory nerves | Endothelin B receptors | Norepinephrine | Endothelin A receptors | PGE | Life Sciences & Biomedicine | Physiology | Science & Technology | Kidney - physiology | Norepinephrine - pharmacology | Antihypertensive Agents - pharmacology | Reflex - physiology | Gene Expression - drug effects | Efferent Pathways - physiology | Kidney Pelvis - metabolism | Reflex - drug effects | Male | Peptides, Cyclic - pharmacology | Efferent Pathways - drug effects | Piperidines - pharmacology | Gene Expression - physiology | Endothelin A Receptor Antagonists | Afferent Pathways - drug effects | Blood Pressure - drug effects | Endothelin-1 - physiology | Myocytes, Smooth Muscle - metabolism | Physical Stimulation | Rats | Sodium, Dietary - urine | Sodium, Dietary - pharmacology | Endothelin B Receptor Antagonists | Receptor, Endothelin A - genetics | Rats, Sprague-Dawley | Dinoprostone - metabolism | Receptor, Endothelin B - genetics | Animals | Models, Biological | Afferent Pathways - physiology | Kidney Pelvis - innervation | Kidney - innervation | Neuroglia - metabolism | Receptor, Endothelin A - metabolism | Substance P - metabolism | Receptor, Endothelin B - metabolism | Oligopeptides - pharmacology | Ganglia, Spinal - metabolism | Kidney Pelvis - drug effects | Nervous system | Biochemistry | Kidneys | Sodium | Dietary minerals | Rodents | Index Medicus | norepinephrine | PGE2 | endothelin B receptors | endothelin A receptors | renal pelvis | substance P | sensory nerves
Journal Article
Diabetes, obesity & metabolism, ISSN 1462-8902, 08/2018, Volume 20, Issue 8, pp. 2019 - 2022
This study aimed to identify the optimal dose of the endothelin-1 receptor antagonist atrasentan with maximal albuminuria reduction and minimal signs of sodium... 
pharmacokinetics | endothelin receptor antagonist | dose‐finding | pharmacodynamics | diabetic nephropathy | dose-finding | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biomarkers - urine | Humans | Body Weight - drug effects | Diabetic Nephropathies - drug therapy | Diabetic Nephropathies - blood | Sodium - metabolism | Dose-Response Relationship, Drug | Drug Therapy, Combination - adverse effects | Diabetic Nephropathies - physiopathology | Renal Insufficiency - physiopathology | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Endothelin A Receptor Antagonists - adverse effects | Renal Insufficiency - complications | Renal Insufficiency - drug therapy | Diabetes Mellitus, Type 2 - complications | Drug Resistance | Endothelin A Receptor Antagonists - therapeutic use | Diabetic Nephropathies - urine | Severity of Illness Index | Double-Blind Method | Endothelin A Receptor Antagonists - administration & dosage | Endothelin A Receptor Antagonists - pharmacokinetics | Biological Variation, Population | Renal Elimination - drug effects | Renal Insufficiency - metabolism | Albuminuria - prevention & control | Atrasentan - therapeutic use | Metabolic Clearance Rate - drug effects | Atrasentan - administration & dosage | Angiotensin Receptor Antagonists - therapeutic use | Atrasentan - adverse effects | Atrasentan - pharmacokinetics | Type 2 diabetes | Antimitotic agents | Medical research | Evaluation | Endothelin | Analysis | Diabetic nephropathies | Albumin | Medicine, Experimental | Antineoplastic agents | Creatinine | Kidneys | Sodium | Diabetes mellitus (non-insulin dependent) | Diabetes mellitus | Index Medicus | Brief Reports | Brief Report
Journal Article
Journal of Applied Physiology, ISSN 1522-1601, 05/2006, Volume 100, Issue 5, pp. 1719 - 1726
Journal Article
Circulation (New York, N.Y.), ISSN 0009-7322, 09/2003, Volume 108, Issue 13, pp. 1646 - 1654
Journal Article
Journal Article
Life sciences (1973), ISSN 0024-3205, 12/2019, Volume 239, pp. 117062 - 117062
Endothelin has been implicated in various processes in the brain, including the modulation of sympathetic responses. The present study examined the... 
Myocardial infarction | Ventricular tachyarrhythmias | Brain endothelin receptors | Vagal response | ETB-receptor | ETA-receptor | Sympathetic response | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Endothelins - pharmacology | Rats, Wistar | Sympathetic Nervous System - drug effects | Endothelin-1 - pharmacology | Male | Receptors, Endothelin - physiology | Endothelins - metabolism | Brain - physiology | Brain - metabolism | Heart Rate - drug effects | Myocardium - metabolism | Tachycardia, Ventricular - metabolism | Heart Rate - physiology | Myocardial Infarction - physiopathology | Autonomic Nervous System - metabolism | Action Potentials - drug effects | Arrhythmias, Cardiac - metabolism | Receptors, Endothelin - metabolism | Rats | Endothelin Receptor Antagonists - metabolism | Myocardial Infarction - metabolism | Endothelin Receptor Antagonists - pharmacology | Tachycardia, Ventricular - physiopathology | Animals | Receptor, Endothelin A - metabolism | Arrhythmias, Cardiac - complications | Receptor, Endothelin B - metabolism | Brain | Heart attacks | Endothelin | Arrhythmia | Regional analysis | Telemetry | Incidence | Heart rate | Receptors | Transmitters | Endothelin receptors | Electrocardiography | Inhomogeneity | Intracerebroventricular administration | Vagus nerve | Ventricle | Index Medicus
Journal Article