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Hypertension, ISSN 0194-911X, 09/2004, Volume 44, Issue 3, pp. 271 - 276
Journal Article
Journal Article
Circulation research, ISSN 0009-7330, 2005, Volume 96, Issue 1, pp. 119 - 126
Remodeling of small arteries is essential in the long-term regulation of blood pressure and blood flow to specific organs or tissues. A large part of the... 
Vascular remodeling | Tissue transglutaminase | Vasoconstriction | Blood flow | INDUCED ACTIVATION | APOPTOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | RESISTANCE ARTERIES | CROSS-LINKING | SPASM | tissue transglutaminase | vascular remodeling | FLOW | STRUCTURAL-CHANGES | ADAPTATION | PERIPHERAL VASCULAR DISEASE | vasoconstriction | HYPERTENSION | HEMATOLOGY | blood flow | Norepinephrine - pharmacology | GTP-Binding Proteins - pharmacology | Mesenteric Arteries - physiology | Cross-Linking Reagents - pharmacology | Endothelin-1 - pharmacology | Transglutaminases - pharmacology | Transglutaminases - genetics | Nitroprusside - pharmacology | Hemorheology | Cadaverine - pharmacology | GTP-Binding Proteins - genetics | Vasoconstriction - physiology | Enzyme Induction - drug effects | Cystamine - pharmacology | Female | Nitric Oxide Donors - pharmacology | Myocytes, Smooth Muscle - cytology | Organ Culture Techniques | Muscle, Skeletal - blood supply | Tretinoin - pharmacology | Vasoconstrictor Agents - pharmacology | Extracellular Matrix Proteins - chemistry | GTP-Binding Proteins - physiology | Guinea Pigs | Vasodilator Agents - pharmacology | Gels | Cell Size - drug effects | Transglutaminases - biosynthesis | Rats | Nitric Oxide - physiology | Papaverine - pharmacology | Arteries - drug effects | Vasoconstriction - drug effects | Extracellular Matrix Proteins - drug effects | Extracellular Matrix - ultrastructure | Animals | Arteries - enzymology | Coronary Vessels - cytology | Vasomotor System - physiology | Collagen | Biotin - pharmacology | Transglutaminases - physiology | GTP-Binding Proteins - biosynthesis | Amines - pharmacology | Mesenteric Arteries - enzymology | Sus scrofa | Biotin - analogs & derivatives | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2010, Volume 30, Issue 4, pp. 749 - 757
OBJECTIVE—Animal and clinical studies have suggested that polyphenols in fruits, red wine, and tea may delay the development of atherosclerosis through their... 
Endothelial dysfunction | Soluble P-selectin | Oxidative stress | Polyphenol | Inflammation | Endothelin-1 | polyphenol | endothelial dysfunction | soluble P-selectin | inflammation | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | BLACK TEA CONSUMPTION | SMOOTH-MUSCLE-CELLS | HEME OXYGENASE-1 | RED WINE | endothelin-1 | HEMATOLOGY | E-DEFICIENT MICE | NF-KAPPA-B | oxidative stress | CORONARY-ARTERY-DISEASE | Inflammation - pathology | Heme Oxygenase-1 - metabolism | Apolipoproteins E - deficiency | Cholesterol - blood | Endothelium, Vascular - drug effects | Male | Aorta - metabolism | F2-Isoprostanes - metabolism | Lignans - pharmacology | Aortic Diseases - metabolism | Inflammation - metabolism | Leukotriene B4 - metabolism | Aortic Diseases - prevention & control | Dioxoles - pharmacology | Polyphenols | Anti-Inflammatory Agents - administration & dosage | Disease Models, Animal | Phenols - pharmacology | Biomarkers - metabolism | Atherosclerosis - pathology | Anti-Inflammatory Agents - pharmacology | Atherosclerosis - physiopathology | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Diet | Endothelium, Vascular - metabolism | Inflammation - prevention & control | Mice | Oxidative Stress - drug effects | Biflavonoids - pharmacology | Chlorogenic Acid - pharmacology | Nitrates - urine | Superoxides - metabolism | Flavonoids - administration & dosage | Flavonoids - pharmacology | Membrane Proteins - metabolism | Aorta - physiopathology | Nitric Oxide Synthase Type III - metabolism | Catechin - pharmacology | Fatty Acids - metabolism | Nitrites - urine | Aorta - drug effects | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Aortic Diseases - physiopathology | Animals | Quercetin - pharmacology | Apolipoproteins E - genetics | Endothelin-1 - urine | P-Selectin - blood | Phenols - administration & dosage | Nitric Oxide - metabolism | Atherosclerosis - prevention & control | Inflammation - physiopathology | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 06/2011, Volume 660, Issue 2-3, pp. 394 - 401
Journal Article
FASEB Journal, ISSN 0892-6638, 12/2010, Volume 24, Issue 12, pp. 4865 - 4876
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2011, Volume 300, Issue 4, pp. H1194 - H1200
Tsai IJ, Croft KD, Puddey IB, Beilin LJ, Barden A. 20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II... 
Arachidonic acid metabolism | Nitric oxide | ω-hydroxylase | Cytochrome P-450 | nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | CYTOCHROME-P450 METABOLITES | omega-hydroxylase | P-450 METABOLITES | RECEPTOR | cytochrome P-450 | arachidonic acid metabolism | ARACHIDONIC-ACID | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | CHROMATOGRAPHY-MASS-SPECTROMETRY | BLOOD-PRESSURE | SELECTIVE INHIBITOR | PROTECTIVE ROLE | PERIPHERAL VASCULAR DISEASE | HYPERTENSION | Tetrazoles - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Endothelin-1 - pharmacology | Humans | Middle Aged | Angiotensin Receptor Antagonists - pharmacology | Male | Peptides, Cyclic - pharmacology | Young Adult | Hydroxyeicosatetraenoic Acids - biosynthesis | Biphenyl Compounds - pharmacology | Piperidines - pharmacology | Adult | Blood Platelets - drug effects | Neutrophils - metabolism | Ionophores - pharmacology | Calcium Channels - drug effects | Angiotensin II - pharmacology | Neutrophils - drug effects | Cells, Cultured | Imidazoles - pharmacology | Cytochrome P-450 Enzyme System | Blood Platelets - metabolism | Aged | Amidines - pharmacology | Pyridines - pharmacology | Oligopeptides - pharmacology | Physiological aspects | Endothelin | Research | Angiotensin | Neutrophils | Studies | Kidneys | Calcium | Blood platelets | Protein synthesis | Rodents | Amino acids | T cell receptors | ACE inhibitors | Cells | Index Medicus
Journal Article
AJP - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 02/2006, Volume 290, Issue 2, pp. L284 - L290
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland Submitted 1 December 2004 ;... 
Y-27632 | HA-1077 | CA2+ SENSITIZATION | PROTEIN-KINASE-C | PHYSIOLOGY | RHO-KINASE | PORCINE CORONARY-ARTERY | TYROSINE KINASES | K+ CURRENTS | VASCULAR SMOOTH-MUSCLE | SIGNAL-TRANSDUCTION | RESPIRATORY SYSTEM | HYPERTENSIVE-RATS | MYOSIN LIGHT CHAIN | Rats, Wistar | Isometric Contraction - drug effects | Endothelin-1 - pharmacology | Maleimides - pharmacology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Male | Myosin-Light-Chain Kinase - antagonists & inhibitors | Potassium Chloride - pharmacology | rho-Associated Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Amides - pharmacology | src-Family Kinases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Rats | Protein Kinase C - antagonists & inhibitors | Pulmonary Artery - physiopathology | Pulmonary Artery - drug effects | Pyrimidines - pharmacology | Vasoconstriction - drug effects | Azepines - pharmacology | Animals | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Genistein - pharmacology | Hypoxia - physiopathology | Pyridines - pharmacology | Staurosporine - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 01/2013, Volume 61, Issue 1, pp. 51 - 62
Cerebral vasospasm after subarachnoid hemorrhage (SAH) is characterized by prolonged severe constriction of the basilar artery, which often leads to ischemic... 
basilar artery | potassium channel | retigabine | celecoxib | cerebral vasospasm | membrane depolarization | RABBIT BASILAR ARTERY | PULMONARY | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | CONSTRICTOR RESPONSES | ANEURYSMAL SUBARACHNOID HEMORRHAGE | DEPENDENT K+ CHANNELS | MILD HYPOTHERMIA | MECHANISMS | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | Myography | Muscle, Smooth, Vascular - metabolism | Endothelin-1 - pharmacology | Basilar Artery - metabolism | Male | Serotonin - pharmacology | Muscle, Smooth, Vascular - physiopathology | KCNQ Potassium Channels - antagonists & inhibitors | Vasospasm, Intracranial - prevention & control | Basilar Artery - physiopathology | Time Factors | Membrane Transport Modulators - pharmacology | Vasospasm, Intracranial - metabolism | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Potassium Channel Blockers - pharmacology | Subarachnoid Hemorrhage - drug therapy | Carbamates - pharmacology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Pyrazoles - pharmacology | Vasoconstrictor Agents - pharmacology | Vasospasm, Intracranial - etiology | Basilar Artery - drug effects | KCNQ Potassium Channels - agonists | Rats | Subarachnoid Hemorrhage - complications | Celecoxib | Arginine Vasopressin - pharmacology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Vasoconstriction - drug effects | Anthracenes - pharmacology | Subarachnoid Hemorrhage - metabolism | Patch-Clamp Techniques | Subarachnoid Hemorrhage - physiopathology | Animals | Signal Transduction - drug effects | Vasospasm, Intracranial - physiopathology | KCNQ Potassium Channels - metabolism | Phenylenediamines - pharmacology | Index Medicus
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 01/2017, Volume 69, Issue 1, pp. 66 - 72
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 05/2009, Volume 296, Issue 5, pp. 1388 - 1397
Endothelin (ET)-1 is a likely candidate for a key role in diabetic vascular complications. However, no abnormalities in the vascular responsiveness to ET-1... 
Nitric oxide | Mitogen-activated protein kinase/extracellular signal regulated kinase | KINASE-ACTIVITY | nitric oxide | mitogen-activated protein kinase/extracellular signal regulated kinase | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | OLETF RATS | ENDOTHELIUM-DEPENDENT RELAXATION | RECEPTOR EXPRESSION | ANGIOTENSIN-II | BASILAR ARTERY | VASCULAR SMOOTH-MUSCLE | GK RAT | INSULIN-RESISTANCE | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | Mesenteric Arteries - physiopathology | Endothelins - pharmacology | Nitriles - pharmacology | Rats, Wistar | Diabetic Angiopathies - etiology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Nitric Oxide Synthase - antagonists & inhibitors | Male | Mesenteric Arteries - drug effects | Peptide Fragments - pharmacology | Peptides, Cyclic - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Nitroprusside - pharmacology | Vasodilation | Dose-Response Relationship, Drug | Diabetic Angiopathies - physiopathology | Piperidines - pharmacology | Diabetic Angiopathies - enzymology | Flavonoids - pharmacology | Nitric Oxide Donors - pharmacology | MAP Kinase Kinase Kinases - antagonists & inhibitors | Diabetes Mellitus, Type 2 - complications | Disease Models, Animal | Butadienes - pharmacology | Angiotensin II - metabolism | Endothelin-1 - metabolism | Diabetes Mellitus, Type 2 - enzymology | Enzyme Inhibitors - pharmacology | Rats | MAP Kinase Kinase Kinases - metabolism | Vasoconstriction - drug effects | Disease Progression | Nitroarginine - pharmacology | Animals | Diabetes Mellitus, Type 2 - physiopathology | Arginine Vasopressin - metabolism | Signal Transduction - drug effects | Receptor, Endothelin A - metabolism | Nitric Oxide Synthase - metabolism | Receptor, Endothelin B - metabolism | Nitric Oxide - metabolism | Oligopeptides - pharmacology | Mesenteric Arteries - enzymology | Proteins | Diabetes | Gene expression | Coronary vessels | Rodents | Cells | Index Medicus
Journal Article
Cardiovascular Research, ISSN 0008-6363, 09/2007, Volume 75, Issue 4, pp. 702 - 709
Objective: We have recently reported that adventitial fibroblasts are able to express endothelin-1 (ET-1) in response to angiotensin II (Ang II) stimulation.... 
Superoxide anion | Adventitial fibroblast | ET-1 | NADPH oxidase | Ang II | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | RESISTANCE ARTERIES | PORCINE CORONARY-ARTERIES | KAPPA-B | adventitial fibroblast | NAD(P)H OXIDASE | COLLAGEN-SYNTHESIS | GENE-EXPRESSION | MYOFIBROBLASTS | SMOOTH-MUSCLE-CELLS | superoxide anion | REGULATED KINASE PATHWAY | Fibroblasts - enzymology | Superoxide Dismutase - genetics | Gene Expression - drug effects | NADPH Oxidases - metabolism | RNA, Messenger - analysis | Superoxide Dismutase - antagonists & inhibitors | Male | Peptides, Cyclic - pharmacology | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt - pharmacology | Spin Labels | Endothelin-1 - analysis | Piperidines - pharmacology | Cyclic N-Oxides - pharmacology | Acetophenones - pharmacology | Endothelin A Receptor Antagonists | Adenoviridae - genetics | NADPH Oxidases - genetics | Aorta | Transduction, Genetic - methods | Dopamine Agonists - pharmacology | Angiotensin II - pharmacology | Collagen Type I - metabolism | Protein Precursors - genetics | Superoxide Dismutase - analysis | Angiotensin II - metabolism | Endothelin-1 - genetics | Endothelin-1 - metabolism | Mice, Inbred C57BL | Biomarkers - analysis | Cells, Cultured | Imidazolines - pharmacology | Endothelin B Receptor Antagonists | Antioxidants - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | NADPH Oxidase 2 | Genetic Vectors - genetics | Membrane Glycoproteins - genetics | Mice, Knockout | Connective Tissue - enzymology | Animals | Image Processing, Computer-Assisted | Collagen Type I - analysis | Mice | Oligopeptides - pharmacology | Muscle, Smooth, Vascular - enzymology | Catecholamines - pharmacology | Angiotensin | Index Medicus
Journal Article
Journal Article
Journal Article