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Immunology, ISSN 0019-2805, 07/2017, Volume 151, Issue 3, pp. 261 - 269
Summary Endothelial dysfunction leading to vascular leak is the hallmark of severe dengue. Vascular leak typically becomes clinically evident 3–6 days after... 
platelet activating factor | NS1 antigen | lipid mediators | dengue | vascular leak | DISEASE SEVERITY | IMMUNOLOGY | TUMOR-NECROSIS-FACTOR | T-CELL RESPONSES | HEMORRHAGIC-FEVER | NITRIC-OXIDE | SHOCK-SYNDROME | PLATELET-ACTIVATING-FACTOR | NF-KAPPA-B | ENDOTHELIAL GROWTH-FACTOR | PLASMA LEAKAGE | Angiopoietins - metabolism | Capillary Permeability | Cytokines - metabolism | Signal Transduction | Humans | Mast Cells - virology | Endothelium, Vascular - physiopathology | Dengue - physiopathology | Dengue - virology | Leukotrienes - metabolism | Platelet Activating Factor - metabolism | Animals | Blood Platelets - metabolism | Endothelium, Vascular - metabolism | Endothelium, Vascular - virology | Dengue Virus - pathogenicity | Inflammation Mediators - metabolism | Mast Cells - metabolism | Dengue - metabolism | Viral Nonstructural Proteins - metabolism | Dengue Virus - metabolism | Blood Platelets - virology | Health aspects | Hemorrhagic fever | Dengue viruses | Drugs | Angiopoietin | Platelet-activating factor | Viremia | Pathogenesis | Interleukin | Viral diseases | Medical services | Viruses | Infections | Activation | Immunology | Pathways | Interleukin 1 | Vascular endothelial growth factor | Vector-borne diseases | Cytokines | Dengue | Discordance | Inflammation | Time measurement | Patients | Fever | Endothelium | Monocytes | Leukotrienes | Tumor necrosis factor | Platelets | Viral infections | Tumors | Review
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2013, Volume 9, Issue 7, p. e1003470
Hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) are diseases caused by hantavirus infections and are characterized by... 
INTRINSIC PATHWAY | HEREDITARY ANGIOEDEMA | SYRIAN-HAMSTER MODEL | VESSEL FORMATION | MICROBIOLOGY | PULMONARY SYNDROME | ANDES VIRUS | VIROLOGY | HEMORRHAGIC-FEVER | NITRIC-OXIDE | VE-CADHERIN | GROWTH-FACTOR | PARASITOLOGY | Endothelium, Vascular - cytology | Muscle, Smooth, Vascular - virology | Human Umbilical Vein Endothelial Cells - metabolism | Muscle, Smooth, Vascular - metabolism | Coculture Techniques | Humans | Capillary Permeability - drug effects | Capillaries - drug effects | Endothelium, Vascular - drug effects | Human Umbilical Vein Endothelial Cells - virology | Protease Inhibitors - pharmacology | Proteolysis - drug effects | Mesenchymal Stromal Cells - cytology | Pulmonary Artery - metabolism | Human Umbilical Vein Endothelial Cells - cytology | Surface Properties | Hantavirus Infections - metabolism | Prekallikrein - antagonists & inhibitors | Capillaries - metabolism | Hantavirus - physiology | Muscle, Smooth, Vascular - drug effects | Capillaries - virology | Mesenchymal Stromal Cells - drug effects | Bradykinin - metabolism | Human Umbilical Vein Endothelial Cells - drug effects | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Hantavirus Infections - virology | Bradykinin - antagonists & inhibitors | Kininogen, High-Molecular-Weight - metabolism | Pulmonary Artery - drug effects | Enzyme Activation - drug effects | Kallikrein-Kinin System - drug effects | Muscle, Smooth, Vascular - cytology | Pulmonary Artery - cytology | Prekallikrein - metabolism | Virus Replication | Endothelium, Vascular - metabolism | Endothelium, Vascular - virology | Factor XII - antagonists & inhibitors | Factor XII - metabolism | Pulmonary Artery - virology | Mesenchymal Stromal Cells - virology | Physiological aspects | Kallikrein | Host-parasite relationships | Hantaviruses | Research | Health aspects | Plasma | Disease | Cytokines | Pathogenesis | Blood vessels | Smooth muscle | Infections | Muscular system | Permeability | Experiments | Fever | Molecular weight | Endothelium | Proteins | Hypotheses | Lymphocytes | Rodents | Phenols | Vascular endothelial growth factor | Viral infections
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e102598
Characterizing the mechanisms by which West Nile virus (WNV) causes blood-brain barrier (BBB) disruption, leukocyte infiltration into the brain and... 
MIGRATION | MATRIX METALLOPROTEINASES | TRANSMIGRATION | ENCEPHALITIS | MULTIDISCIPLINARY SCIENCES | CENTRAL-NERVOUS-SYSTEM | NECROSIS-FACTOR-ALPHA | INFECTION | ICAM-1 | EXPRESSION | T-CELLS | Leukocytes - pathology | Humans | Brain - virology | Monocytes - metabolism | Brain - metabolism | Lymphocytes - virology | Monocytes - pathology | Blood-Brain Barrier - virology | Transendothelial and Transepithelial Migration - physiology | Endothelial Cells - virology | West Nile Fever - pathology | Lymphocytes - metabolism | West Nile Fever - virology | West Nile virus - physiology | Endothelial Cells - metabolism | Cells, Cultured | West Nile Fever - metabolism | E-Selectin - metabolism | Permeability | Blood-Brain Barrier - metabolism | Monocytes - virology | Intercellular Adhesion Molecule-1 - metabolism | Lymphocytes - pathology | Cell Adhesion - physiology | Endothelium, Vascular - metabolism | Endothelium, Vascular - virology | Leukocytes - virology | Endothelium, Vascular - pathology | Endothelial Cells - pathology | In Vitro Techniques | Vascular Cell Adhesion Molecule-1 - metabolism | Leukocytes - metabolism | Brain | Encephalitis | Analysis | West Nile fever | Models | Spyware | Endothelium | Animal models | Vascular cell adhesion molecule 1 | Leukocyte migration | Neuropathology | Pathogenesis | Central nervous system | Blocking antibodies | Membrane permeability | Antibodies | Viruses | Infections | Leukocytes | VLA-4 antigen | Cell adhesion & migration | Cell adhesion molecules | Blood-brain barrier | Mac1 protein | Lymphocytes | Cell adhesion | Intercellular adhesion molecule 1 | Invasiveness | Blocking | Pharmacology | Inflammation | Adhesion | Endothelial cells | Medicine | White blood cells | E-selectin | Monocytes | Brain research | Infectious diseases | West Nile virus | Infiltration | Microvasculature | Cams | Disruption | Cell migration | Chemokines
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2013, Volume 9, Issue 1, p. e1003133
Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.... 
ANTIBODIES | CATTLE | JAAGSIEKTE SHEEP | MICROBIOLOGY | INTERFERON ANTAGONIST | ORTHOBUNYAVIRUS | NONSTRUCTURAL PROTEIN NSS | CLONED CDNA | RESCUE | VIROLOGY | VALLEY FEVER VIRUS | AKABANE VIRUS | PARASITOLOGY | Neurons - pathology | Sequence Deletion | Bunyaviridae Infections - pathology | Virulence | Cerebral Cortex - pathology | Molecular Sequence Data | Bunyaviridae Infections - mortality | Host-Pathogen Interactions - immunology | Cerebellar Diseases - immunology | Cerebellar Diseases - pathology | Cattle | Spinal Cord - pathology | Base Sequence | Viral Tropism | Cerebellar Diseases - virology | Disease Models, Animal | Endothelium, Vascular - immunology | Amino Acid Sequence | Cell Line | Neurons - virology | Orthobunyavirus - genetics | Orthobunyavirus - pathogenicity | Neurons - immunology | Cerebral Cortex - virology | Survival Rate | Bunyaviridae Infections - immunology | Disease Progression | Spinal Cord - immunology | Immunity, Innate - immunology | Animals | Virus Replication | Cerebral Cortex - immunology | Bunyaviridae Infections - virology | Endothelium, Vascular - virology | Endothelium, Vascular - pathology | Sheep | Mice | Orthobunyavirus - isolation & purification | Virus Cultivation | Spinal Cord - virology | Vacuoles | RNA viruses | Tropisms | Physiological aspects | Host-parasite relationships | Research | Health aspects | Immune system | Cell culture | Brain | Pathogenesis | Viruses | Infections | Veterinary medicine | Experiments
Journal Article
PLoS Pathogens, ISSN 1553-7366, 11/2017, Volume 13, Issue 11, p. e1006673
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2014, Volume 10, Issue 9, p. e1004400
Altered cell metabolism inherently connected h pathological conditions including cancer and viral infections. Kaposi' coma-associated herpesvirus (KSHV) is the... 
DNA-SEQUENCES | MITOCHONDRIAL BIOGENESIS | PRIMARY EFFUSION LYMPHOMA | TARGET RECOGNITION | MICROBIOLOGY | FACTOR-I | HYPOXIA | CANCER | VIROLOGY | GENE-EXPRESSION | ENCODED MIRNAS | LYMPHATIC ENDOTHELIAL-CELLS | PARASITOLOGY | Cell Proliferation | Sarcoma, Kaposi - metabolism | Virus Latency | Humans | Bone Neoplasms - pathology | Osteosarcoma - virology | Bone Neoplasms - metabolism | Tumor Cells, Cultured | Endothelial Cells - virology | Real-Time Polymerase Chain Reaction | Herpesvirus 8, Human - physiology | Osteosarcoma - metabolism | Aerobiosis | Endothelial Cells - metabolism | Lactic Acid - metabolism | RNA, Messenger - genetics | Bone Neoplasms - virology | Oxygen Consumption | Mitochondria - metabolism | Sarcoma, Kaposi - virology | Mitochondria - pathology | Reverse Transcriptase Polymerase Chain Reaction | Virion - metabolism | Blotting, Western | Sarcoma, Kaposi - pathology | Energy Metabolism | Endothelium, Vascular - metabolism | Gene Expression Regulation, Viral | Endothelium, Vascular - virology | Mitochondria - virology | Glucose - metabolism | Endothelium, Vascular - pathology | MicroRNAs - genetics | Endothelial Cells - pathology | Osteosarcoma - pathology | Cell metabolism | Genetic research | Genetic aspects | MicroRNA | Research | Kaposi's sarcoma | Medical research | Genes | Viruses | Biosynthesis | Mitochondrial DNA | Metabolism | Experiments | Mitochondria | Algorithms | MicroRNAs | Protein expression | Kaposis sarcoma | Viral infections | Cancer
Journal Article