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Scientific Reports, ISSN 2045-2322, 05/2014, Volume 4, Issue 1, pp. 4828 - 4828
Periodontitis has been implicated as a risk factor for metabolic disorders such as type 2 diabetes, atherosclerotic vascular diseases, and non-alcoholic fatty... 
C-REACTIVE PROTEIN | RHEUMATOID-ARTHRITIS | POLYMERASE-CHAIN-REACTION | PORPHYROMONAS-GINGIVALIS | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | CORONARY-HEART-DISEASE | DIET-INDUCED OBESITY | PERIODONTAL-DISEASE | ADIPOSE-TISSUE | Glucose Intolerance - metabolism | Inflammation - pathology | Ileum - pathology | Metabolic Diseases - pathology | Diabetes Mellitus, Type 2 - microbiology | Periodontitis - microbiology | Glucose Intolerance - microbiology | Ileum - metabolism | Male | Glucose Intolerance - pathology | Diabetes Mellitus, Type 2 - metabolism | Endotoxemia - pathology | Periodontitis - metabolism | Dental Plaque - microbiology | Gingiva - metabolism | Inflammation - metabolism | Microbiota | Gingiva - pathology | Insulin Resistance - physiology | Tight Junction Proteins - metabolism | Disease Models, Animal | Endotoxemia - microbiology | Porphyromonas gingivalis | Inflammation - microbiology | Cytokines - metabolism | Mice, Inbred C57BL | Periodontitis - pathology | Insulin - metabolism | Animals | Metabolic Diseases - metabolism | Mice | Diabetes Mellitus, Type 2 - pathology | Endotoxemia - metabolism | Gingiva - microbiology | Ileum - microbiology | Metabolic Diseases - microbiology | Liver diseases | Diabetes mellitus | Oral administration | Dental plaque | Inflammation | Gene expression | Insulin | Ileum | Glucose tolerance | Intolerance | Fatty liver | Vascular diseases | Periodontitis | Arteriosclerosis | Rodents | Gingiva | Endotoxemia | Metabolic disorders | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, pp. 11295 - 11295
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, pp. 34666 - 34666
The endotoxin lipopolysaccharide (LPS) promotes sepsis, but bacterial peptides also promote inflammation leading to sepsis. We found, intraperitoneal... 
CONTROLLED-TRIAL | TUMOR-NECROSIS-FACTOR | BACTERIAL LIPOPROTEINS | D-GALACTOSAMINE | YERSINIA-PESTIS | MULTIDISCIPLINARY SCIENCES | DOUBLE-BLIND | SEPTIC SHOCK | PLATELET-ACTIVATING-FACTOR | TNF-ALPHA | SEVERE SEPSIS | Liver - pathology | Endotoxemia - genetics | Humans | Tumor Necrosis Factor-alpha - genetics | Macrophages, Peritoneal - pathology | Platelet Activating Factor - immunology | Endotoxemia - chemically induced | Interleukin-1beta - genetics | Liver - immunology | Bacterial Outer Membrane Proteins - toxicity | Liver - drug effects | Cyclooxygenase 2 - genetics | Endotoxemia - immunology | Tumor Necrosis Factor-alpha - immunology | Cyclooxygenase 2 - immunology | Macrophages, Peritoneal - drug effects | Neutrophils - pathology | Lung - pathology | Peroxidase - immunology | Lipopolysaccharides - toxicity | Mice, Inbred C57BL | Neutrophils - drug effects | Gene Expression Regulation | Neutrophils - immunology | Interleukin-1beta - immunology | Macrophages, Peritoneal - immunology | Platelet Activating Factor - genetics | Cell Adhesion - drug effects | Lipoproteins - toxicity | Mice, Knockout | Animals | Lung - drug effects | Survival Analysis | Peroxidase - genetics | RAW 264.7 Cells | Escherichia coli Proteins - toxicity | Mice | Primary Cell Culture | Endotoxemia - mortality | Lung - immunology | Albinism | Platelet-activating factor | Liver | mRNA | Leukocytes | Gene expression | Macrophages | IL-1β | Polymyxin B | Lipopolysaccharides | Membrane proteins | Prostaglandin endoperoxide synthase | E coli | Tumor necrosis factor | TLR2 protein | Collagen | Rodents | Toll-like receptors | Sepsis | Leukocytes (polymorphonuclear) | Cyclooxygenase-2 | Endotoxemia | Peritoneum | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e115148 - e115148
Aim: We sought develop and characterize a diet-induced model of metabolic syndrome and its related diseases. Methods: The experimental animals (Spague-Dawley... 
FRUCTOSE | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | NONALCOHOLIC STEATOHEPATITIS | MICE | DYSFUNCTION | LIVER-DISEASE | INDUCED OBESITY | BLOOD-PRESSURE | ADIPOSE-TISSUE | Sucrose - administration & dosage | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Intestine, Small - pathology | Humans | Adipose Tissue - pathology | Diet, High-Fat - adverse effects | Endotoxemia - chemically induced | Pancreas - drug effects | Pancreas - pathology | Rats | Sucrose - adverse effects | Endotoxemia - pathology | Metabolic Syndrome - chemically induced | Animals | Liver - drug effects | Non-alcoholic Fatty Liver Disease - chemically induced | Intestine, Small - drug effects | Diabetes Mellitus, Type 2 - chemically induced | Diabetes Mellitus, Type 2 - pathology | Metabolic Syndrome - pathology | Adipose Tissue - drug effects | Disease Models, Animal | Adipose tissues | Diet | Liver | Insulin resistance | Glucose | Liver cirrhosis | Sugars | Dextrose | Adipose tissue | Sucrose | Pathogenesis | Dyslipidemia | Science | Adipocytes | Metabolic syndrome | Macrophages | Small intestine | High fat diet | Lipopolysaccharides | Interleukin 6 | Hyperglycemia | Fatty liver | Rodents | Animal tissues | Blood pressure | Degeneration | Pancreas | Endotoxemia | Chronic illnesses | Carbohydrates | Obesity | Medical research | Liver diseases | Diabetes mellitus | Inflammation | Permeability | Insulin | Diseases | Glucose tolerance | Nutrition research | Cirrhosis | Intolerance | Hepatocytes | Fibrosis | Infiltration | Islets of Langerhans | Diabetes | Metabolic disorders | Hypertrophy | Apoptosis | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 9, pp. 3507 - 3512
Journal Article
Neuroscience, ISSN 0306-4522, 2009, Volume 160, Issue 3, pp. 606 - 615
Abstract Injury to the cerebellum and brainstem is becoming increasingly recognized in prematurely born infants. The role of infection/inflammation in... 
Neurology | infection | brainstem | LPS | PREMATURE-INFANT | IN-UTERO | RISK-FACTORS | PERIVENTRICULAR LEUKOMALACIA | NECROSIS-FACTOR-ALPHA | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | OVINE FETUS | OLIGODENDROCYTE PROGENITORS | LIPOPOLYSACCHARIDE | EXPOSURE | Microglia - metabolism | Oligodendroglia - metabolism | Cerebellar Diseases - etiology | Escherichia coli | Endotoxemia - pathology | Cerebellar Cortex - embryology | Cerebellum - embryology | DNA-Binding Proteins - metabolism | Cerebellar Diseases - pathology | Brain Stem - pathology | Nerve Fibers, Myelinated - pathology | Cell Death | Microglia - pathology | Female | Cerebellar Diseases - embryology | Lipopolysaccharides - toxicity | Cerebellum - pathology | Nerve Tissue Proteins - metabolism | Oligodendroglia - pathology | Pregnancy | Animals | Cerebellar Cortex - pathology | Endotoxemia - complications | Fetal Diseases - pathology | Endotoxins - administration & dosage | Sheep | Neurosciences | Nucleoproteins | Water quality | Hydroxylases | Universities and colleges | Health aspects | Intermediate filament proteins | Mitogens | Protein binding | Index Medicus | Cerebellum | toxicity | pathology | Endotoxins | MEDICIN OCH HÄLSOVETENSKAP | Lipopolysaccharides | administration & dosage | Cerebellar Cortex | embryology | Endotoxemia | MEDICAL AND HEALTH SCIENCES | Cerebellar Diseases | DNA-Binding Proteins | complications | Myelinated | Fetal Diseases | Nerve Tissue Proteins | etiology | Microglia | Oligodendroglia | metabolism | Brain Stem | Nerve Fibers
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 08/2018, Volume 67, Issue 8, pp. 1512 - 1523
Altering the gut microbiome may be beneficial to the host and recently arose as a promising strategy to manage obesity. Here, we investigated the relative... 
Non-alcoholic Fatty Liver Disease - pathology | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Liver - pathology | Endotoxemia - prevention & control | Cadherins - metabolism | Diet, High-Fat - adverse effects | Glucose Intolerance - microbiology | Male | Muscle, Skeletal - metabolism | Glucose Intolerance - pathology | Phylogeny | Dysbiosis - microbiology | Obesity - microbiology | Glucose Intolerance - prevention & control | Cadherins - genetics | Fecal Microbiota Transplantation - adverse effects | Glucose Intolerance - physiopathology | Fatty Acids, Omega-3 - metabolism | Intestines - pathology | Liver - metabolism | Non-alcoholic Fatty Liver Disease - microbiology | Gastrointestinal Microbiome | Insulin Resistance | Mice, Transgenic | Obesity - physiopathology | Endotoxemia - etiology | Intestinal Mucosa - microbiology | Non-alcoholic Fatty Liver Disease - physiopathology | Permeability | Dysbiosis - physiopathology | Dysbiosis - therapy | Obesity - pathology | Animals | Intestines - microbiology | Obesity - prevention & control | Non-alcoholic Fatty Liver Disease - prevention & control | Dietary Sucrose - adverse effects | Diet, Carbohydrate Loading - adverse effects | Intestines - physiopathology | Intestinal Mucosa - pathology | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Endocrinology and metabolism
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2012, Volume 122, Issue 6, pp. 1973 - 1990
EC activation and dysfunction have been linked to a variety of vascular inflammatory disease states. The function of microRNAs (miRNAs) in vascular EC... 
CELL-ADHESION MOLECULE-1 | TRANSCRIPTION FACTORS | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR-NECROSIS-FACTOR | DEPENDENT INDUCTION | LEUKOCYTE RECRUITMENT | HUMAN-ENDOTHELIAL-CELLS | ACUTE MYELOID-LEUKEMIA | PROGNOSTIC-SIGNIFICANCE | EXPRESSION PROFILES | SIGNAL-TRANSDUCTION PATHWAY | alpha Karyopherins - metabolism | Endotoxemia - therapy | Leukocytes - pathology | Vasculitis - metabolism | Acute Lung Injury - therapy | Endotoxemia - genetics | Humans | NF-kappa B - immunology | Critical Illness | Acute Lung Injury - genetics | MicroRNAs - metabolism | NF-kappa B - metabolism | Endotoxemia - pathology | Vasculitis - immunology | Leukocytes - immunology | Vasculitis - genetics | alpha Karyopherins - immunology | E-Selectin - genetics | Endotoxemia - immunology | Vascular Cell Adhesion Molecule-1 - genetics | Acute Lung Injury - metabolism | Vascular Cell Adhesion Molecule-1 - immunology | Vasculitis - therapy | Lipopolysaccharides - toxicity | Endothelial Cells - metabolism | E-Selectin - metabolism | E-Selectin - immunology | MicroRNAs - immunology | Acute Lung Injury - pathology | Endothelial Cells - immunology | Animals | NF-kappa B - genetics | alpha Karyopherins - genetics | Acute Lung Injury - immunology | Mice | MicroRNAs - genetics | Endothelial Cells - pathology | Endotoxemia - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Leukocytes - metabolism | Index Medicus | Abridged Index Medicus
Journal Article