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1. Full Text Differing toxicity of ambient particulate matter (PM) in global cities
by Li, Jing and Li, Xinyue and Chen, Haoxuan and Wang, Jing and Wang, Minfei and Zhang, Xiangyu and Cao, Junji and Shen, Fangxia and Wu, Yan and Xu, Siyu and Fan, Hanqing and Da, Guillaume and Huang, Ru-jin and Chan, Chak K and De Jesus, Alma Lorelei and Morawska, Lidia and Yao, Maosheng
Atmospheric Environment, ISSN 1352-2310, 09/2019, Volume 212, pp. 305 - 315
Air quality is often assessed using particulate matter (PM) mass concentration without considering its toxicity, thus possibly leading to improper control... 
Air quality | Oxidative potential | PM toxicity | Biologicals | UNITED-STATES | MORTALITY | DIESEL EXHAUST PARTICLES | OXIDATIVE STRESS | ENVIRONMENTAL SCIENCES | AIR-POLLUTION | PM2.5 EXPOSURE | ENDOTOXIN CONCENTRATIONS | GENERATION | SOURCE APPORTIONMENT | METEOROLOGY & ATMOSPHERIC SCIENCES | TEMPORAL DISTRIBUTION | Air pollution | Air quality management | Environmental health
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2. Full Text In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential - the RAPTES project
by Steenhof, Maaike and Gosens, Ilse and Strak, Maciej and Godri, Krystal J and Hoek, Gerard and Cassee, Flemming R and Mudway, Ian S and Kelly, Frank J and Harrison, Roy M and Lebret, Erik and Brunekreef, Bert and Janssen, Nicole A.H and Pieters, Raymond H.H
Particle and Fibre Toxicology, ISSN 1743-8977, 09/2011, Volume 8, Issue 1, pp. 26 - 26
Background: Ambient particulate matter (PM) exposure is associated with respiratory and cardiovascular morbidity and mortality. To what extent such effects are... 
AIRWAY EPITHELIAL-CELLS | UNITED-STATES | ENRICHMENT SYSTEM VACES | UTAH VALLEY | CYTOTOXIC RESPONSES | CHEMICAL-COMPOSITION | ENDOTOXIN CONCENTRATIONS | ULTRAFINE PARTICLES | TOXICOLOGY | COARSE AMBIENT PARTICLES | FINE PM2.5 | Particulate Matter - toxicity | Air Pollutants - analysis | Cell Line | Data Interpretation, Statistical | Enzyme-Linked Immunosorbent Assay | Oxidation-Reduction | Environmental Monitoring - methods | Particle Size | Netherlands | Animals | Particulate Matter - analysis | Particulate Matter - chemistry | Macrophages, Alveolar - drug effects | Mice | Cell Culture Techniques | Macrophages, Alveolar - metabolism | Air Pollutants - toxicity | Endotoxins - analysis | Macrophages, Alveolar - immunology | Air Pollutants - chemistry | Cytokines - immunology | Mortality | Physiological aspects | United Kingdom | Research | Macrophages | Particles | Steel-works | Outdoor air quality | Oxidative stress | Health sciences | Polycyclic aromatic hydrocarbons | Airborne particulates | Risk assessment | Metals | Environmental health | Air pollution | Epidemiology | Manuscripts
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3. Full Text Role of oxidative stress in Deoxynivalenol induced toxicity
by Mishra, Sakshi and Dwivedi, Premendra D and Pandey, Haushila P and Das, Mukul
Food and Chemical Toxicology, ISSN 0278-6915, 10/2014, Volume 72, pp. 20 - 29
Deoxynivalenol (DON) is a toxin that causes a variety of toxic effects with symptoms such as diarrhoea and low weight gain. To date, no review has addressed... 
Antioxidants | Lipid peroxidation | Oxidative stress | Reactive oxygen species | Deoxynivalenol | DNA damage | FOOD SCIENCE & TECHNOLOGY | DNA-DAMAGE | TRICHOTHECENE VOMITOXIN DEOXYNIVALENOL | IN-VITRO | ENDOTOXIN POTENTIATION | FUSARIUM MYCOTOXINS | NATURAL OCCURRENCE | TOXICOLOGY | T-2 TOXIN | ESOPHAGEAL CANCER | ACTIVATED PROTEIN-KINASES | CELL-LINE | DNA Damage - drug effects | Trichothecenes - toxicity | Animals | Reactive Oxygen Species - metabolism | Fusarium - chemistry | Apoptosis - drug effects | Reactive Nitrogen Species - metabolism | Humans | Lipid Metabolism - drug effects | Models, Animal | Oxidative Stress - drug effects | Nitric oxide | Analysis | Superoxide | Mitogens | Food | Index Medicus
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4. Full Text Persistence of detectable insecticidal proteins from Bacillus thuringiensis (Cry) and toxicity after adsorption on contrasting soils
by Hung, T.P and Truong, L.V and Binh, N.D and Frutos, R and Quiquampoix, H and Staunton, S
Environmental Pollution, ISSN 0269-7491, 01/2016, Volume 208, Issue Pt B, pp. 318 - 325
Insecticidal Cry, or Bt, proteins are produced by the soil-endemic bacterium, and some genetically modified crops. Their environmental fate depends on... 
Persistence | Soil | Adsorption | Toxicity | Bacillus thuringiensis | HUMIC ACIDS | TOXIN | TRANSGENIC PLANTS | CORN TISSUE | ENVIRONMENTAL SCIENCES | SUBSP KURSTAKI | CRYSTAL PROTEINS | WATER-CONTENT | DEGRADATION | MONTMORILLONITE | BT CROPS | Endotoxins - metabolism | Environmental Monitoring | Soil Microbiology | Larva - metabolism | Manduca | Bacterial Proteins - analysis | Insecta - metabolism | Animals | Bacterial Proteins - toxicity | Soil - chemistry | Pesticide Residues - analysis | Pesticide Residues - toxicity | Insecticides - toxicity | Hemolysin Proteins - metabolism | Crops, Agricultural - metabolism | Insecticides - analysis | Proteins | Soils | Genetically modified crops | Soil disinfection | Index Medicus | Geochemistry | Earth Sciences | Sciences of the Universe
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5. Full Text Microglia toxicity in preterm brain injury
by Baburamani, Ana A and Supramaniam, Veena G and Hagberg, Henrik and Mallard, Carina and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
Reproductive Toxicology, ISSN 0890-6238, 09/2014, Volume 48, Issue 100, pp. 106 - 112
Microglia are the resident phagocytic cells of the central nervous system. During brain development they are also imperative for apoptosis of excessive... 
Perinatal brain injury | Neuroinflammation | CELLS IN-VITRO | NITRIC-OXIDE SYNTHASE | FETAL SHEEP | PERIVENTRICULAR LEUKOMALACIA | WHITE-MATTER INJURY | GLUTAMATE-RECEPTOR | ORGANOTYPIC SLICE CULTURES | TUMOR-NECROSIS-FACTOR | REPRODUCTIVE BIOLOGY | TOXICOLOGY | ACTIVATED MICROGLIA | BACTERIAL-ENDOTOXIN SENSITIZES | Brain Diseases - metabolism | Prenatal Injuries - pathology | Animals | Brain Diseases - pathology | Microglia - physiology | Prenatal Injuries - physiopathology | Humans | Infant, Premature | Brain Diseases - physiopathology | Infant, Newborn | Prenatal Injuries - metabolism | Brain | Injuries | Index Medicus | Neurosciences | Farmakologi och toxikologi | Pharmacology and Toxicology | Neurovetenskaper
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6. Full Text Specific binding between Bacillus thuringiensis Cry9Aa and Vip3Aa toxins synergizes their toxicity against Asiatic rice borer (Chilo suppressalis)
by Wang, Zeyu and Fang, Longfa and Zhou, Zishan and Pacheco, Sabino and Gómez, Isabel and Song, Fuping and Soberón, Mario and Zhang, Jie and Bravo, Alejandra
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 29, pp. 11447 - 11458
The bacterium Bacillus thuringiensis produces several insecticidal proteins, such as the crystal proteins (Cry) and the vegetative insecticidal proteins (Vip).... 
pesticide | SPODOPTERA-FRUGIPERDA MIDGUT | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUSCEPTIBILITY | RECEPTOR | VEGETATIVE INSECTICIDAL PROTEIN | epitope mapping | synergistic activity | CRY11AA TOXIN | toxin | DIFFERS | Bacillus | insect | synergism | SITES | protein-protein interaction | BORDER MEMBRANE-VESICLES | CRYSTAL PROTEIN | LEPIDOPTERA | Endotoxins - metabolism | Amino Acid Sequence | Insecticides - chemistry | Bacillus thuringiensis - chemistry | Lepidoptera - microbiology | Lepidoptera - physiology | Bacterial Proteins - chemistry | Models, Molecular | Hemolysin Proteins - chemistry | Protein Interaction Maps | Host-Pathogen Interactions | Animals | Bacterial Proteins - toxicity | Insecticides - metabolism | Endotoxins - chemistry | Hemolysin Proteins - toxicity | Protein Binding | Bacterial Proteins - metabolism | Bacillus thuringiensis - physiology | Binding Sites | Insecticides - toxicity | Oryza - parasitology | Endotoxins - toxicity | Hemolysin Proteins - metabolism | Index Medicus | Microbiology
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7. Full Text Amino acids Y229 and F603 are involved in Bacillus thuringiensis Cry1Ac δ-endotoxin stability and toxicity
by Dammak, Mariam and Ali, Mamdouh Ben and Jaoua, Samir and Tounsi, Slim
FEMS Microbiology Letters, ISSN 0378-1097, 04/2012, Volume 329, Issue 1, pp. 54 - 60
Abstract Bacillus thuringiensis Cry1Ac toxin shares structurally five conserved blocs with the other δ-endotoxins. To study the role of some amino acids... 
specific mutation | δ‐endotoxin | activity | conserved blocs | Bacillus thuringiensis | structure | Conserved blocs | Activity | δ-endotoxin | Structure | Specific mutation | SUBSTITUTION | DOMAIN-III | INSECTICIDAL CRYSTAL PROTEINS | TOXIN | MEMBRANE | RESOLUTION | MICROBIOLOGY | d-endotoxin | SUBSP KURSTAKI | GENE | CONSERVED REGION | EXPRESSION | Bacillus thuringiensis - chemistry | Hemolysin Proteins - genetics | Bacterial Proteins - chemistry | Amino Acids - genetics | Hemolysin Proteins - chemistry | Bacterial Proteins - toxicity | Bacillus thuringiensis - pathogenicity | Bacillus thuringiensis - genetics | Larva - drug effects | Endotoxins - chemistry | Hemolysin Proteins - toxicity | Mutant Proteins - toxicity | Lepidoptera - drug effects | Protein Stability | Mutagenesis, Site-Directed | Endotoxins - genetics | Bacterial Proteins - genetics | Mutant Proteins - genetics | Models, Molecular | Animals | Mutant Proteins - chemistry | Survival Analysis | Protein Conformation | Endotoxins - toxicity | Amino Acid Substitution | Proteins | Larvae | Toxicity | Crystallization | Endotoxins | Cry1Ac toxin | Amino acids | Toxins | Hydrophobicity | Mutation | Three dimensional models | Mutants | Index Medicus
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8. Full Text In vitro methods for assessing nanoparticle toxicity
by Savage, Dustin T and Hilt, J. Zach and Dziubla, Thomas D
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1894, pp. 1 - 29
As a consequence of their increase in annual production and widespread distribution in the environment, nanoparticles potentially pose a significant public... 
Mechanisms of toxicity | Reactive oxygen species | Nanoparticle-cell interaction | Nanoparticle characterization | Nanoparticle toxicity | Biocompatibility | Nanomaterials | In vitro assays
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9. Full Text A novel Vip3Aa16-Cry1Ac chimera toxin: Enhancement of toxicity against Ephestia kuehniella, structural study and molecular docking
by Sellami, Sameh and Jemli, Sonia and Abdelmalek, Nouha and Cherif, Marwa and Abdelkefi-Mesrati, Lobna and Tounsi, Slim and Jamoussi, Kais
International Journal of Biological Macromolecules, ISSN 0141-8130, 10/2018, Volume 117, pp. 752 - 761
Vip3A protein has been widely used for crop protection and for delay resistance to existing insecticidal Cry toxins. During current study, a fusion between and... 
Model prediction | Chimera toxin | Protein-protein docking | Vip3Aa16 | Bacillus thuringiensis | Cry1Ac | Biopesticides | DOMAIN-III | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HELIOTHIS-VIRESCENS | VEGETATIVE INSECTICIDAL PROTEIN | RAY CRYSTAL-STRUCTURE | SPODOPTERA-LITTORALIS | BACILLUS-THURINGIENSIS TOXIN | MIDGUT | DELTA-ENDOTOXIN | SUGAR TONGS | CHEMISTRY, APPLIED | BINDING | Amino Acid Sequence | Endotoxins - genetics | Endotoxins - chemistry | Hemolysin Proteins - genetics | Bacterial Proteins - genetics | Recombinant Fusion Proteins - genetics | Protein Conformation | Recombinant Fusion Proteins - toxicity | Molecular Docking Simulation | Recombinant Fusion Proteins - chemistry | Endotoxins - toxicity | Microbial biotechnology | Analysis | Biotechnological microorganisms | Index Medicus
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10. Full Text Co-Chaperone-Mediated Suppression of LPS-Induced Cardiac Toxicity Through NFκB Signaling
by Ohno, Marumi and Moore, Rick and Myers, Page and Negishi, Masahiko
SHOCK, ISSN 1073-2322, 08/2018, Volume 50, Issue 2, pp. 248 - 254
ABSTRACTCo-chaperone cytoplasmic constitutive active/androstane receptor retention protein (CCRP), a member of heat shock protein (HSP) 40, was first... 
cytokine | CCRP | heart rate | fraction shortening | endotoxin | SURGERY | ACTIVATION | RECEPTOR | SEPSIS | HEART | OVEREXPRESSION | INHIBITION | LIPOPOLYSACCHARIDE | INDUCED MYOCARDIAL DYSFUNCTION | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | EXPRESSION | CRITICAL CARE MEDICINE
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11. Full Text Toxins in Transgenic Crop Byproducts May Affect Headwater Stream Ecosystems
by E. J. Rosi-Marshall and J. L. Tank and T. V. Royer and M. R. Whiles and M. Evans-White and C. Chambers and N. A. Griffiths and J. Pokelsek and M. L. Stephen
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2007, Volume 104, Issue 41, pp. 16204 - 16208
Corn (Zea mays L.) that has been genetically engineered to produce the Cry1Ab protein (Bt corn) is resistant to lepidopteran pests. Bt corn is widely planted... 
Caddisflies | Crops | Mortality | Corn | Pollen | Headwaters | Aquatic insects | Plant litter | Transgenic plants | Streams | Genetically modified crops | LEPIDOSTOMATIDAE | BT CORN | genetically modified crops | DEPOSITION | FIELD | MULTIDISCIPLINARY SCIENCES | BACILLUS-THURINGIENSIS-ISRAELENSIS | IMPACT | CORN POLLEN | MONARCH LARVAE | caddisflies | DYNAMICS | NONTARGET MACROINVERTEBRATES | Zea mays - genetics | Plants, Genetically Modified - genetics | Endotoxins - genetics | Hemolysin Proteins - genetics | Insecta | Bacterial Proteins - genetics | Bacterial Toxins - toxicity | Zea mays - parasitology | Lepidoptera - pathogenicity | Zea mays - toxicity | Animals | Bacterial Proteins - toxicity | Water Pollutants, Chemical - toxicity | Ecosystem | Hemolysin Proteins - toxicity | Bacterial Toxins - genetics | Fresh Water - analysis | Plants, Genetically Modified - toxicity | Plant Diseases - parasitology | Endotoxins - toxicity | Plant toxins | Stream ecology | Environmental aspects | Influence | Research | Health aspects | Caddis-flies | Biological Sciences
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12. Full Text Bacillus thuringiensis Cry1Ia10 and Vip3Aa protein interactions and their toxicity in Spodoptera spp. (Lepidoptera)
by Bergamasco, V.B and Mendes, D.R.P and Fernandes, O.A and Desidério, J.A and Lemos, M.V.F
Journal of Invertebrate Pathology, ISSN 0022-2011, 02/2013, Volume 112, Issue 2, pp. 152 - 158
► Expression and purification of Cry1Ia10 and Vip3Aa in BL21(DE3). ► Detection of a putative 65 kDa membrane receptor by ligand blotting. competition analysis... 
Spodoptera frugiperda | Spodoptera cosmioides | In vitro competition assays | Receptor binding | Spodoptera albula | Spodoptera eridania | COTTON BOLL-WEEVIL | ALKALINE-PHOSPHATASE | ESCHERICHIA-COLI | VEGETATIVE INSECTICIDAL PROTEIN | HELICOVERPA-ARMIGERA | HELIOTHIS-VIRESCENS LARVAE | ZOOLOGY | DELTA-ENDOTOXINS | FALL ARMYWORM | BRUSH-BORDER MEMBRANE | BINDING-SITES | Endotoxins - metabolism | Pest Control, Biological | Intestinal Mucosa - metabolism | Cloning, Organism | Receptors, Cell Surface - metabolism | Intestinal Mucosa - drug effects | Life Cycle Stages | Host-Pathogen Interactions | Animals | Bacterial Proteins - toxicity | Insecticides - metabolism | Larva | Spodoptera - metabolism | Hemolysin Proteins - toxicity | Bacterial Proteins - metabolism | Spodoptera - drug effects | Insect Proteins - metabolism | Insecticides - toxicity | Endotoxins - toxicity | Hemolysin Proteins - metabolism | Index Medicus
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13. Full Text Resveratrol Alleviates Endotoxin-Induced Myocardial Toxicity via the Nrf2 Transcription Factor
by Hao, Enkui and Lang, Fangfang and Chen, Yong and Zhang, Huilin and Cong, Xiao and Shen, Xiaoqian and Su, Guohai
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e69452
Background/Aims: Septic cardiomyopathy is a severe condition that remains a challenge for clinical management. This study investigated whether the natural... 
CARDIAC-SPECIFIC OVEREXPRESSION | SIGNALING PATHWAY | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | REPERFUSION INJURY | HEART-FAILURE | MICROVASCULAR ENDOTHELIAL-CELLS | NECROSIS-FACTOR-ALPHA | TNF-ALPHA |