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PLoS ONE, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, pp. e9367 - e9367
Background: Mitochondrial dysfunction and degradation takes a central role in current paradigms of neurodegeneration in Parkinson's disease (PD). Loss of DJ-1... 
PINK1 | FUSION | ENERGETIC DEPRESSION | BIOLOGY | MAMMALIAN AUTOPHAGY | DYSFUNCTION | NEURODEGENERATIVE DISEASES | DROSOPHILA | EARLY-ONSET PARKINSONISM | CELL-DEATH | PUNCTA-FORMATION | Oncogene Proteins - genetics | Phosphorylation | Reactive Oxygen Species - metabolism | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy | Fibroblasts - ultrastructure | Lysosomes - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Fibroblasts - metabolism | Parkinson Disease - pathology | Oncogene Proteins - metabolism | Oxidative Phosphorylation | Mitochondria - metabolism | Parkinson Disease - genetics | Microscopy, Electron | Blotting, Western | Mice, Knockout | Peroxiredoxins | Lysosomes - ultrastructure | Protein Deglycase DJ-1 | Animals | Fibroblasts - cytology | Mice | Mutation | Mitogen-Activated Protein Kinase 1 - metabolism | Genes | Genetic aspects | Oxidative stress | Cell culture | Reactive oxygen species | Animal models | Parkinson's disease | Laboratories | Downstream effects | Parkinsons disease | Homeostasis | Lysosomes | Kinases | Accumulation | Degradation | Proteins | Mitochondria | Neurodegeneration | Penicillin | Fibroblasts | Aging | Physiology | Membrane potential | Movement disorders | Neurodegenerative diseases | Extracellular signal-regulated kinase | Organelles | PARK7 protein | Neurology | Brain research | Hypoxia | Electron transport | Respiration | Alzheimers disease | Phagocytosis | Apoptosis | Integrity | Index Medicus
Journal Article
Journal Article
Progress in Human Geography, ISSN 0309-1325, 12/2015, Volume 39, Issue 6, pp. 702 - 728
This paper considers the limits and potential of ‘urban metabolism’ to conceptualize city processes. Three ‘ecologies’ of urban metabolism have emerged. Each... 
political ecology | metaphor | industrial ecology | urban ecology | boundary object | interdisciplinary research | urban metabolism | SUSTAINABILITY | CITIES | FLOW | INTERDISCIPLINARY | CITY | LAND-USE | SCIENCE | ECOSYSTEM | GEOGRAPHY | ENERGETIC METABOLISM | WATER
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 06/2016, Volume 310, Issue 11, pp. H1520 - H1532
Circadian clocks are critical modulators of metabolism. However, mechanistic links between cell autonomous clocks and metabolic processes remain largely... 
Heart | Biotin | Chronobiology | Nutrition | Metabolism | Liver | OXIDATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | RAG GTPASES | liver | biotin | FATTY-ACID-METABOLISM | heart | nutrition | GLUCOSE-HOMEOSTASIS | OBESITY | chronobiology | GENE-EXPRESSION | REV-ERB-ALPHA | PERIPHERAL VASCULAR DISEASE | metabolism | MICE | CONTRACTILE FUNCTION | Heart Diseases - metabolism | Male | CLOCK Proteins - genetics | Circadian Clocks - genetics | Carbon-Carbon Ligases - metabolism | ARNTL Transcription Factors - deficiency | Time Factors | Biotin - metabolism | Biotin - administration & dosage | Disease Models, Animal | Chronobiology Disorders - genetics | ARNTL Transcription Factors - genetics | Genetic Predisposition to Disease | Biotinylation | Heart Diseases - physiopathology | Liver - metabolism | Mice, Inbred C57BL | Chronobiology Disorders - physiopathology | Methylmalonyl-CoA Decarboxylase - metabolism | Pyruvate Carboxylase - metabolism | Symporters - metabolism | Mice, Knockout | Phenotype | Animals | Energy Metabolism | Myocytes, Cardiac - metabolism | Carbon-Carbon Lyases - metabolism | Protein Processing, Post-Translational | Mutation | Acetyl-CoA Carboxylase - metabolism | Heart Diseases - genetics | Chronobiology Disorders - metabolism | Post-translational modification | Circadian rhythms | Physiological aspects | Physiological research | Research | Protein synthesis | Rodents | Protein expression | Cardiomyocytes | Circadian rhythm | Gene expression | Index Medicus | Energetics and Metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2017, Volume 114, Issue 49, pp. 13048 - 13053
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 07/2016, Volume 311, Issue 1, pp. H64 - H75
Myocardial fatty acid beta-oxidation is critical for the maintenance of energy homeostasis and contractile function in the heart, but its regulation is still... 
Heart | β-oxidation | MicroRNA | Thioredoxin-interacting protein | Nuclear factor Y | CARDIOMYOCYTE CIRCADIAN CLOCK | PRESSURE-OVERLOAD | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | LIPID-METABOLISM | CONTRACTILE DYSFUNCTION | DIURNAL-VARIATIONS | THIOREDOXIN-INTERACTING-PROTEIN | thioredoxin-interacting protein | ACTIVATED RECEPTOR-ALPHA | heart | beta-oxidation | CARDIAC-HYPERTROPHY | microRNA | nuclear factor Y | PERIPHERAL VASCULAR DISEASE | RAT-HEART | TRANSCRIPTIONAL REGULATION | Mitochondrial Trifunctional Protein, beta Subunit - genetics | AMP-Activated Protein Kinases - metabolism | Carnitine O-Palmitoyltransferase - genetics | Humans | CCAAT-Binding Factor - genetics | Mitochondrial Trifunctional Protein, beta Subunit - metabolism | Male | MicroRNAs - metabolism | Myocytes, Cardiac - enzymology | CCAAT-Binding Factor - metabolism | Thioredoxins - genetics | Transfection | RNA Interference | Carnitine O-Palmitoyltransferase - metabolism | Thioredoxins - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Fatty Acids - metabolism | Cell Line | Carnitine Acyltransferases - metabolism | Oxidation-Reduction | Signal Transduction | Isolated Heart Preparation | Mice, Inbred C57BL | Rats | Genotype | Mice, Knockout | Gene Expression Regulation, Enzymologic | Carrier Proteins - genetics | Phenotype | Animals | Carrier Proteins - metabolism | Energy Metabolism | Myocytes, Cardiac - metabolism | MicroRNAs - genetics | AMP-Activated Protein Kinases - genetics | Carnitine Acyltransferases - genetics | Physiological aspects | Oxidation-reduction reaction | Observations | Thioredoxin | Fatty acids | Carnitine | Protein binding | Proteins | Genes | Homeostasis | Cardiomyocytes | Oxidation | Metabolism | Index Medicus | Energetics and Metabolism
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2015, Volume 309, Issue 7, pp. H1157 - H1165
Nutritional energy support during extracorporeal membrane oxygenation (ECMO) should promote successful myocardial adaptation and eventual weaning from the ECMO... 
Cardiac metabolism | Pediatrics | Fatty acids | Extracorporeal circulation | OXIDATION | CARDIAC-DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | PYRUVATE | fatty acids | cardiac metabolism | extracorporeal circulation | MECHANICAL CIRCULATORY SUPPORT | CHAIN FATTY-ACID | CHILDREN | RAT HEARTS | SKELETAL-MUSCLE | pediatrics | IN-VIVO | PERIPHERAL VASCULAR DISEASE | CYCLE | Gas Chromatography-Mass Spectrometry | Mitochondria, Heart - metabolism | Carbon Isotopes | Male | Caprylates - pharmacology | Mitochondria, Heart - drug effects | Caprylates - metabolism | Heptanoates - metabolism | Extracorporeal Membrane Oxygenation | Swine | Adenosine Triphosphate - metabolism | Myocardium - metabolism | Oxidation-Reduction - drug effects | Models, Animal | Acyl Coenzyme A - metabolism | Heptanoates - pharmacology | Leucine - metabolism | Magnetic Resonance Spectroscopy | Citric Acid Cycle - drug effects | Lipid Metabolism | Acetyl Coenzyme A - metabolism | Animals | Energy Metabolism | Heart - drug effects | Citric Acid - metabolism | Adenosine Diphosphate - metabolism | Sus scrofa | Metabolites | Physiological aspects | Protein biosynthesis | Genetic aspects | Research | Oxidation | Mass spectrometry | Carbon | Chromatography | Index Medicus | critical care | Environmental Molecular Sciences Laboratory | cardiac disease | amino acids | Energetics and Metabolism
Journal Article
Journal Article
Cardiovascular Research, ISSN 0008-6363, 12/2012, Volume 96, Issue 3, pp. 466 - 475
Increasing energy storage capacity by elevating creatine and phosphocreatine (PCr) levels to increase ATP availability is an attractive concept for protecting... 
Ischaemia | Myocardial stunning | Metabolism | Creatine kinase | Cardiac energetics | Reperfusion injury | CARDIAC-FUNCTION | ENERGY | CARDIAC & CARDIOVASCULAR SYSTEMS | MOUSE HEART | HEART-FAILURE | KNOCKOUT MICE | ISCHEMIA-REPERFUSION INJURY | FAILING HEART | INCREASED SUSCEPTIBILITY | IN-VIVO | RAT-HEART | Myocardial Reperfusion Injury - etiology | Myocardial Infarction - genetics | Up-Regulation | Mitochondria, Heart - metabolism | Oxidative Stress | Ventricular Function, Left | Heart Failure - physiopathology | Necrosis | Myocardial Reperfusion Injury - pathology | Ventricular Remodeling | Glycogen - metabolism | Time Factors | Membrane Transport Proteins - genetics | Myocardial Infarction - pathology | Myocardium - metabolism | Creatine - metabolism | Membrane Transport Proteins - metabolism | Myocardial Infarction - physiopathology | Disease Models, Animal | Cell Line | Mitochondrial Membrane Transport Proteins - metabolism | Myocardial Stunning - physiopathology | Mice, Inbred C57BL | Heart Failure - genetics | Mice, Transgenic | Myocardium - pathology | Heart Failure - metabolism | Heart Failure - pathology | Magnetic Resonance Imaging, Cine | Myocardial Infarction - metabolism | Myocardial Reperfusion Injury - physiopathology | Myocardial Stunning - pathology | Myocardial Reperfusion Injury - metabolism | Myocardial Stunning - metabolism | Myocardial Stunning - prevention & control | Animals | Energy Metabolism | Mice | Myocardial Infarction - prevention & control | Phosphocreatine - metabolism | Myocardial Reperfusion Injury - prevention & control | Index Medicus | Original
Journal Article