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1. Full Text Enhancer of zeste homolog 2 (EZH2) inhibitors
by Gulati, Nitya and Béguelin, Wendy and Giulino-Roth, Lisa
Leukemia & Lymphoma, ISSN 1042-8194, 07/2018, Volume 59, Issue 7, pp. 1574 - 1585
Dysregulation of the histone methyltransferase EZH2 plays a critical role in the development of a variety of malignancies including B-cell lymphomas. As a... 
EZH2 inhibitors | non-Hodgkin lymphoma | Epigenetic | SELECTIVE-INHIBITION | B-CELL LYMPHOMAS | POLYCOMB | GERMINAL CENTER FORMATION | POTENT | CANCER EPIGENETICS | ONCOLOGY | NON-HODGKIN-LYMPHOMA | HISTONE METHYLTRANSFERASE EZH2 | MUTATIONS | HEMATOLOGY | REPRESSIVE COMPLEX 2 | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Lymphoma, B-Cell - metabolism | Humans | Enzyme Inhibitors - pharmacology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Drug Resistance, Neoplasm | Treatment Outcome | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Combined Modality Therapy | Lymphoma, B-Cell - genetics | Molecular Targeted Therapy | Enzyme Inhibitors - therapeutic use | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Lymphoma, B-Cell - pathology | Antineoplastic Agents - pharmacology | Epigenesis, Genetic - drug effects | Drug Evaluation, Preclinical | Lymphoma, B-Cell - drug therapy
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2. Full Text Enhancer of Zeste homolog 2 (EZH2) induces epithelial-mesenchymal transition in endometriosis
by Zhang, Qi and Dong, Peixin and Liu, Xishi and Sakuragi, Noriaki and Guo, Sun-Wei
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 6804 - 12
EZH2, a subunit of the polycomb repressive complex 2 (PRC2) catalyzing trimethylation of histone H3 lysine 27 (H3K27), induces epithelial-mesenchymal... 
CELLS | METHYLATION | INVASION | PLATELETS | MULTIDISCIPLINARY SCIENCES | HEPATOCYTE GROWTH-FACTOR | GROUP PROTEIN EZH2 | PROLIFERATION | E-CADHERIN | EXPRESSION | TO-MYOFIBROBLAST TRANSDIFFERENTIATION | Cell Line | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Snail Family Transcription Factors - metabolism | Cadherins - metabolism | Vimentin - metabolism | Humans | Cells, Cultured | Endometriosis - pathology | Animals | Snail Family Transcription Factors - genetics | Vimentin - genetics | Endometriosis - metabolism | Epithelial-Mesenchymal Transition | Adult | Female | Mice | Mice, Inbred BALB C | Histones - metabolism | Cadherins - genetics | Polycomb Repressive Complex 2 - metabolism | Vimentin | Transcription factors | Pain perception | Wound healing | Mesenchyme | Epithelial cells | Endometriosis | E-cadherin | Polycomb group proteins | Lysine | Fibrosis | Platelets | Snail protein | Methylation | Cell migration | Endometrium | Histone H3
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3. Full Text Enhancer of zeste homolog 2 (EZH2) promotes tumour cell migration and invasion via epigenetic repression of E‐cadherin in renal cell carcinoma
by Liu, Li and Xu, Zhibing and Zhong, Lei and Wang, Hang and Jiang, Shuai and Long, Qilai and Xu, Jiejie and Guo, Jianming
BJU International, ISSN 1464-4096, 02/2016, Volume 117, Issue 2, pp. 351 - 362
Objective To investigate the molecular mechanism and clinical significance for an oncogenic role of enhancer of zeste homolog 2 (EZH2) in renal cell carcinoma... 
kidney cancer | RCC | DZNep | EMT | survival | EZH2 | DEVELOPMENTAL REGULATORS | METASTASIS | ESTABLISHMENT | POLYCOMB | VIRUS X PROTEIN | HEPATOCELLULAR-CARCINOMA | THERAPY | EMBRYONIC STEM-CELLS | UROLOGY & NEPHROLOGY | EXPRESSION | Immunohistochemistry | Carcinoma, Renal Cell - pathology | Neoplasm Invasiveness | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Polycomb Repressive Complex 2 - drug effects | Cadherins - drug effects | Blotting, Western | Enhancer of Zeste Homolog 2 Protein | Cell Movement - drug effects | Disease-Free Survival | Animals | Heterografts | Chromatin Immunoprecipitation | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Carcinoma, Renal Cell - drug therapy | Kidney Neoplasms - drug therapy | Polycomb Repressive Complex 2 - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Real-Time Polymerase Chain Reaction | Epigenetic inheritance | Carcinoma, Renal cell | Analysis
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4. Full Text Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice
by Dudakovic, Amel and Camilleri, Emily T and Paradise, Christopher R and Samsonraj, Rebekah M and Gluscevic, Martina and Paggi, Carlo Alberto and Begun, Dana L and Khani, Farzaneh and Pichurin, Oksana and Ahmed, Farah S and Elsayed, Ranya and Elsalanty, Mohammed and McGee-Lawrence, Meghan E and Karperien, Marcel and Riester, Scott M and Thaler, Roman and Westendorf, Jennifer J and van Wijnen, Ane J
Journal of biological chemistry, ISSN 0021-9258, 08/2018, Volume 293, Issue 33, pp. 12894 - 12907
Epigenetic mechanisms control skeletal development and osteoblast differentiation. Pharmacological inhibition of the histone 3 Lys-27 (H3K27) methyltransferase... 
Molecular Biology | Biochemistry | Cell Biology | methyltransferase | OSTEOBLAST DIFFERENTIATION | EPIGENETIC CONTROL | CHROMATIN | enhancer of zeste homolog | BIOCHEMISTRY & MOLECULAR BIOLOGY | bone | osteoblast | osteogenesis | LINEAGE SPECIFICATION | epigenetics | MESENCHYMAL STEM-CELLS | histone methylation | skeleton | OSTEOCALCIN GENE | SKELETAL GROWTH | chromatin regulation | bone development | INTEGRATIVE GENOMICS VIEWER | histone | HISTONE MODIFICATIONS | METHYLTRANSFERASE EZH2 | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Osteogenesis - physiology | Animals | Cell Cycle - physiology | Female | Male | Mice, Transgenic | Mice | Osteoblasts - cytology | Sex Characteristics | Osteoblasts - metabolism
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5. Full Text Effects of Enhancer of Zeste Homolog 2 (EZH2) Expression on Brain Glioma Cell Proliferation and Tumorigenesis
by Cheng, Tianci and Xu, Yinghui
Medical science monitor : international medical journal of experimental and clinical research, ISSN 1643-3750, 10/2018, Volume 24, pp. 7249 - 7255
Background: Brain glioma is a type of common primary intracranial malignant tumor, the prognosis of which is frequently unfavorable. Enhancer of zeste homolog... 
MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | Cell Proliferation | PROTEIN EZH2 | PHOSPHORYLATION | POLYCOMB | Cells | BREAST-CANCER | GLIOBLASTOMA | INHIBITION | Glioma | PROSTATE-CANCER | HISTONE METHYLTRANSFERASE EZH2 | RNA, Small Interfering - genetics | Prognosis | Humans | Middle Aged | Brain Neoplasms - pathology | Male | Carcinogenesis | Brain Neoplasms - metabolism | Proto-Oncogene Proteins c-akt - genetics | Proto-Oncogene Proteins c-myc - biosynthesis | Heterografts | Glioblastoma - genetics | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Adult | Female | Glioblastoma - metabolism | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Cell Proliferation - physiology | Brain Neoplasms - genetics | Proto-Oncogene Proteins c-akt - biosynthesis | Animals | Glioblastoma - pathology | Enhancer of Zeste Homolog 2 Protein - biosynthesis | Mice | Proto-Oncogene Proteins c-myc - genetics
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6. Full Text Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98
by Alajez, N.M and Shi, W and Hui, A.B.Y and Bruce, J and Lenarduzzi, M and Ito, E and Yue, S and O'Sullivan, B and Liu, F.-F
Cell Death and Disease, ISSN 2041-4889, 10/2010, Volume 1, Issue 10, pp. e85 - e85
There is increasing evidence supporting the role of members of the polycomb group (PcG) gene family in tumor development and progression. However, their... 
Nasopharyngeal carcinoma (NPC) | MicroRNA | EZH2 | CELLS | VIRUS | nasopharyngeal carcinoma (NPC) | RADIATION | CELL BIOLOGY | BREAST-CANCER | PATHWAY | GROWTH | GENES | GROUP PROTEINS | microRNA | POLYCOMB REPRESSIVE COMPLEX | EXPRESSION | Nasopharyngeal Carcinoma | Nasopharyngeal Neoplasms - metabolism | Oligonucleotide Array Sequence Analysis | Cell Survival | Down-Regulation | Humans | Computational Biology | MicroRNAs - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Enhancer of Zeste Homolog 2 Protein | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Polycomb Repressive Complex 2 | Cell Differentiation | Carcinoma - metabolism | 3' Untranslated Regions | Apoptosis | Original
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7. Full Text Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells
by Bugide, Suresh and Green, Michael R and Wajapeyee, Narendra
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2018, Volume 115, Issue 15, pp. E3509 - E3518
Natural killer (NK) cell-mediated tumor cell eradication could inhibit tumor initiation and progression. However, the factors that regulate NK cell-mediated... 
HCC | NK cell ligands | NK cells | DNMT3A | EZH2 | ACTIVATION | MULTIDISCIPLINARY SCIENCES | NKG2D RECEPTOR | SORAFENIB | FAMILY | INNATE IMMUNE RECOGNITION | LIGANDS | REJECTION | NIVOLUMAB | EXPRESSION | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Small Molecule Libraries - pharmacology | Humans | Intracellular Signaling Peptides and Proteins - immunology | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA Methylation | Carcinoma, Hepatocellular - drug therapy | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Carcinoma, Hepatocellular - genetics | Killer Cells, Natural - immunology | Liver Neoplasms - pathology | Carcinoma, Hepatocellular - immunology | Intracellular Signaling Peptides and Proteins - genetics | Promoter Regions, Genetic | Enhancer of Zeste Homolog 2 Protein - genetics | GPI-Linked Proteins - immunology | Liver Neoplasms - genetics | Down-Regulation | Liver Neoplasms - drug therapy | Liver Neoplasms - immunology | Hep G2 Cells | Carcinoma, Hepatocellular - pathology | Enhancer of Zeste Homolog 2 Protein - immunology | Cell Line, Tumor | Ligands | GPI-Linked Proteins - genetics | Killer cells | Usage | Care and treatment | Hepatoma | Health aspects | Biological Sciences | PNAS Plus
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8. Full Text The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD)
by Sarmento, Olga F and Svingen, Phyllis A and Xiong, Yuning and Sun, Zhifu and Bamidele, Adebowale O and Mathison, Angela J and Smyrk, Thomas C and Nair, Asha A and Gonzalez, Michelle M and Sagstetter, Mary R and Baheti, Saurabh and McGovern, Dermot P.B and Friton, Jessica J and Papadakis, Konstantinos A and Gautam, Goel and Xavier, Ramnik J and Urrutia, Raul A and Faubion, William A
Journal of Biological Chemistry, ISSN 0021-9258, 01/2017, Volume 292, Issue 2, pp. 706 - 722
Regulatory T (Treg) cells expressing the transcription factor FOXP3 play a pivotal role in maintaining immunologic self-tolerance. We and others have shown... 
METHYLATION | REPRESSION | PHOSPHORYLATION | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | REGULATORY T-CELLS | GENE-EXPRESSION | DIFFERENTIATION | FOXP3 | PLASTICITY | Forkhead Transcription Factors - immunology | Enhancer of Zeste Homolog 2 Protein - genetics | Humans | Mice, Transgenic | Forkhead Transcription Factors - genetics | Crohn Disease - immunology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Animals | Crohn Disease - pathology | Enhancer of Zeste Homolog 2 Protein - immunology | Th17 Cells - immunology | Mice | Gene Regulatory Networks - immunology | Cytokines - genetics | Cytokines - immunology | Th17 Cells - pathology | Molecular Bases of Disease | histone methylation | transcriptional corepressor | T helper cells | Crohn's disease | regulatory T cell | inflammatory bowel disease (IBD) | forkhead box P3 (FOXP3) | epigenetics | EZH2
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9. Full Text Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)‑ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors
by Kung, Pei-Pei and Rui, Eugene and Bergqvist, Simon and Bingham, Patrick and Braganza, John and Collins, Michael and Cui, Mei and Diehl, Wade and Dinh, Dac and Fan, Connie and Fantin, Valeria R and Gukasyan, Hovhannes J and Hu, Wenyue and Huang, Buwen and Kephart, Susan and Krivacic, Cody and Kumpf, Robert A and Li, Gary and Maegley, Karen A and McAlpine, Indrawan and Nguyen, Lisa and Ninkovic, Sacha and Ornelas, Martha and Ryskin, Michael and Scales, Stephanie and Sutton, Scott and Tatlock, John and Verhelle, Dominique and Wang, Fen and Wells, Peter and Wythes, Martin and Yamazaki, Shinji and Yip, Brian and Yu, Xiu and Zehnder, Luke and Zhang, Wei-Guo and Rollins, Robert A and Edwards, Martin
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2016, Volume 59, Issue 18, pp. 8306 - 8325
A new enhancer of zeste homolog 2 (EZH2) inhibitor series comprising a substituted phenyl ring joined to a dimethylpyridone moiety via an amide linkage has... 
SELECTIVE-INHIBITION | CHEMISTRY, MEDICINAL | MECHANISM | HISTONE H3 | B-CELL LYMPHOMAS | NON-HODGKIN-LYMPHOMA | MUTATIONS | HYPERTRIMETHYLATION | METHYLTRANSFERASE EZH2 | CANCER | DISCOVERY | Neoplasms - metabolism | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Enhancer of Zeste Homolog 2 Protein - metabolism | Humans | Models, Molecular | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - chemistry | Mice, SCID | Neoplasms - drug therapy | Isoquinolines - chemistry | Animals | Isoquinolines - pharmacology | Cyclization | Drug Design | Lactams - pharmacology | Cell Line, Tumor | Isoquinolines - therapeutic use | Female | Antineoplastic Agents - pharmacology | Mice | Pyridones - therapeutic use | Pyridones - chemistry | Pyridones - pharmacology | Lactams - chemistry
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10. Full Text Telomerase reverse transcriptase (TERT) ‐ enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma
by Ahmad, Fahim and Patrick, Shruti and Sheikh, Touseef and Sharma, Vikas and Pathak, Pankaj and Malgulwar, Prit Benny and Kumar, Anupam and Joshi, Shanker Datt and Sarkar, Chitra and Sen, Ellora
Journal of Neurochemistry, ISSN 0022-3042, 12/2017, Volume 143, Issue 6, pp. 671 - 683
Elevated expression of enhancer of zeste homolog 2 (EZH2), a histone H3K27 methyltransferase, was observed in gliomas harboring telomerase reverse... 
MSI | ATM | TERT | FASN | EZH2 | PENTOSE-PHOSPHATE PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MISMATCH REPAIR GENE | PROMOTER MUTATIONS | NEUROSCIENCES | COLON-CANCER | STEM-LIKE CELLS | EPITHELIAL-CELLS | PROSTATE-CANCER | IN-VIVO | HUMAN GLIOMAS | FATTY-ACID SYNTHASE | Enhancer of Zeste Homolog 2 Protein - metabolism | Humans | Animals | Heterografts | DNA Damage - physiology | Mice, Nude | Glioblastoma - pathology | Cell Line, Tumor | Glioblastoma - metabolism | Telomerase - metabolism | Mice | Gene Expression Regulation, Neoplastic - physiology | Lipid Metabolism - physiology | Synthesis | DNA damage | Analysis | DNA | Physiological aspects | Development and progression | Genetic engineering | Fatty acids | Glioblastoma multiforme | DNA repair | Telomerase | Phosphorylation | Telomerase reverse transcriptase | RNA-directed DNA polymerase | Brain tumors | Glioblastoma | Methyltransferase | Lipids | Homology | Microsatellite instability | Accumulation | Rodents | Xenografts | Ataxia | Lipid metabolism | Inhibition | Deoxyribonucleic acid--DNA | Microsatellites | Stability | Pharmacology | siRNA | Metabolism | Gene expression | Glioma | Ataxia telangiectasia | Ataxia telangiectasia mutated protein | Mutation | Tumors
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11. Full Text Inhibition of Human Enhancer of Zeste Homolog 2 with Tambjamine Analogs
by Kotev, Martin and Manuel-Manresa, Pilar and Hernando, Elsa and Soto-Cerrato, Vanessa and Orozco, Modesto and Quesada, Roberto and Pérez-Tomás, Ricardo and Guallar, Victor
Journal of Chemical Information and Modeling, ISSN 1549-9596, 08/2017, Volume 57, Issue 8, pp. 2089 - 2098
Combining computational modeling, de novo compound synthesis, and in vitro and cellular assays, we have performed an inhibition study against the enhancer of... 
CHEMISTRY, MEDICINAL | COMPUTER SCIENCE, INFORMATION SYSTEMS | ANION TRANSPORT | POLYCOMB | CHEMISTRY, MULTIDISCIPLINARY | CELL-DEATH | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | THERAPEUTIC TARGET | PROSTATE-CANCER | GROUP PROTEIN EZH2 | LYMPHOMA | SIMULATIONS | HISTONE METHYLTRANSFERASE | Càncer | Computational modeling | Enzyme | Enginyeria biomèdica | Enhancer of zeste homolog 2 (EZH2) | Investigació | Research | Enzims | Enzyme activation | Àrees temàtiques de la UPC | Cancer
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12. Full Text Overexpression of enhancer of zeste homolog 2 (EZH2) characterizes an aggressive subset of prostate cancers and predicts patient prognosis independently from pre- and postoperatively assessed clinicopathological parameters
by Melling, Nathaniel and Thomsen, Erik and Tsourlakis, Maria C.hristina and Kluth, Martina and Hube-Magg, Claudia and Minner, Sarah and Koop, Christina and Graefen, Markus and Heinzer, Hans and Wittmer, Corinna and Sauter, Guido and Wilczak, Waldemar and Huland, Hartwig and Simon, Ronald and Schlomm, Thorsten and Steurer, Stefan and Krech, Till
Carcinogenesis, ISSN 0143-3334, 11/2015, Volume 36, Issue 11, pp. 1333 - 1340
Enhancer of zeste homolog 2 (EZH2) plays an important role in tumor development and progression by interacting with histone and nonhistone proteins. In the... 
GENOMIC INSTABILITY | BREAST EPITHELIAL-CELLS | ANDROGEN RECEPTOR | GENE FUSIONS | ONCOLOGY | TUMOR-CELL PROLIFERATION | POLYCOMB GROUP PROTEIN | EARLY PSA RECURRENCE | HISTONE DEACETYLASE | PROGRESSION | DELETION | Multivariate Analysis | Prostatic Neoplasms - metabolism | Cell Proliferation | Polycomb Repressive Complex 2 - genetics | Prognosis | Tissue Array Analysis | Humans | Middle Aged | Male | Prostate - surgery | Prostate - metabolism | Prostate - pathology | Prostatic Neoplasms - pathology | Gene Expression | Neoplasm Recurrence, Local - metabolism | Neoplasm Recurrence, Local - prevention & control | Prostatic Neoplasms - surgery | Kaplan-Meier Estimate | Postoperative Period | Enhancer of Zeste Homolog 2 Protein | Prostatic Neoplasms - mortality | Disease-Free Survival | Oncogene Proteins, Fusion - genetics | Prostatectomy | Aged | Polycomb Repressive Complex 2 - metabolism | Preoperative Period | Index Medicus
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13. Full Text Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
by Wagener, Nina and Macher-Goeppinger, Stephan and Pritsch, Maria and Hüsing, Johannes and Hoppe-Seyler, Karin and Schirmacher, Peter and Pfitzenmaier, Jesco and Haferkamp, Axel and Hoppe-Seyler, Felix and Hohenfellner, Markus
BMC Cancer, ISSN 1471-2407, 10/2010, Volume 10, Issue 1, pp. 524 - 524
Background: The enhancer of zeste homolog 2 (EZH2) gene exerts oncogene-like activities and its (over) expression has been linked to several human... 
PROSTATE | SURVIVAL | ONCOLOGY | MARKER | PREDICT | ENHANCER-OF-ZESTE-HOMOLOG-2 GENE | GROUP PROTEIN EZH2 | DOUBLE-BLIND | PROLIFERATION | IDENTIFICATION | CANCER | Prognosis | Humans | Middle Aged | Risk Factors | Gene Expression Regulation, Neoplastic | Male | Treatment Outcome | Kidney Neoplasms - metabolism | Biomarkers, Tumor | Kidney Neoplasms - diagnosis | Immunohistochemistry - methods | Carcinoma, Renal Cell - metabolism | Neoplasm Metastasis | Carcinoma, Renal Cell - diagnosis | Female | Aged | Gene silencing | Transcription factors | Physiological aspects | Genetic aspects | Carcinoma, Renal cell | Research
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14. Full Text Enhancer of Zeste Homolog 2 (EZH2) Promotes Progression of Cholangiocarcinoma Cells by Regulating Cell Cycle and Apoptosis
by Nakagawa, Shigeki and Okabe, Hirohisa and Sakamoto, Yasuo and Hayashi, Hiromitsu and Hashimoto, Daisuke and Yokoyama, Naomi and Sakamoto, Keita and Kuroki, Hideyuki and Mima, Kosuke and Nitta, Hidetoshi and Imai, Katsunori and Chikamoto, Akira and Watanabe, Masayuki and Beppu, Toru and Baba, Hideo
Annals of Surgical Oncology, ISSN 1068-9265, 12/2013, Volume 20, Issue S3, pp. 667 - 675
Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb repressive complex 2 (PRC2). When present in PRC2, EZH2 catalyzes trimethylation on... 
Oncology | Medicine & Public Health | Surgical Oncology | Surgery | BREAST-CANCER | SURGERY | DEVELOPMENTAL REGULATORS | BILIARY EPITHELIA | ONCOLOGY | EMBRYONIC STEM-CELLS | PROSTATE-CANCER | GROUP PROTEIN EZH2 | PROLIFERATION | POLYCOMB | EXPRESSION | HISTONE METHYLTRANSFERASE | Polycomb Repressive Complex 2 - antagonists & inhibitors | RNA, Small Interfering - genetics | Cell Proliferation | Polycomb Repressive Complex 2 - genetics | Prognosis | Follow-Up Studies | Humans | Male | Cholangiocarcinoma - metabolism | Immunoenzyme Techniques | Bile Ducts, Extrahepatic | Flow Cytometry | Biomarkers, Tumor - metabolism | Bile Ducts, Intrahepatic | Female | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Bile Duct Neoplasms - metabolism | Bile Duct Neoplasms - secondary | RNA, Messenger - genetics | Cholangiocarcinoma - mortality | Survival Rate | Lymphatic Metastasis | Reverse Transcriptase Polymerase Chain Reaction | Disease Progression | Enhancer of Zeste Homolog 2 Protein | Cholangiocarcinoma - pathology | Cell Cycle | Bile Duct Neoplasms - mortality | Aged | Biomarkers, Tumor - genetics | Neoplasm Staging | Polycomb Repressive Complex 2 - metabolism | Apoptosis
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