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Journal Article
Oncology Reports, ISSN 1021-335X, 10/2017, Volume 38, Issue 4, pp. 2132 - 2140
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 03/2015, Volume 16, Issue 3, pp. 450 - 459
Methionine enkephalin (MENK), an endogenous neuropeptide, plays an crucial role in both neuroendocrine and immune systems. CD4+Foxp3+ regulatory T cells... 
regulatory T cells | Smad2/3 protein | cancer immunoregulation | transforming growth factor-β | methionine enkephalin | regulatory T cell reprogramming | forkhead box P3 transcription factor | Forkhead box P3 transcription factor | Methionine enkephalin | Transforming growth factor-β | Cancer immunoregulation | Regulatory T cells | Regulatory T cell reprogramming | GITR | Fas ligand | interleukin-2 | TGF-BETA | protein gel blot | HELPER-CELLS | 3 protein | WB | real-time PCR | MTS | MFI | TGF-, | CTLA-4 | 3- | flow cytometry | CCR4 | IF | MODULATION | immunofluorescence | ANTIGEN | INDUCE FOXP3 | CONVERSION | Tregs | 5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium | DENDRITIC CELL | real-time polymerase chain reaction | IL-2 | glucocorticoid-induced TNFR | SUPPRESSION | Smad2 | MENK | cytotoxic T Lymphocyte Antigen-4 | FCM | median fluorescence intensity | ONCOLOGY | FasL | CC chemokine receptor 4 | transforming growth factor | Foxp3 | EXPRESSION | CARCINOMA | inner salt | Forkhead Transcription Factors - immunology | Transforming Growth Factor beta - immunology | T-Lymphocytes, Regulatory - metabolism | Humans | CD4-Positive T-Lymphocytes - metabolism | Sarcoma - drug therapy | Sarcoma - pathology | T-Lymphocytes, Regulatory - immunology | Sarcoma - metabolism | T-Lymphocytes, Regulatory - drug effects | Animals | Flow Cytometry | Forkhead Transcription Factors - metabolism | Immunotherapy | Cell Line, Tumor | Enkephalin, Methionine - administration & dosage | Cell Proliferation - drug effects | Mice | Transforming Growth Factor beta - metabolism | CD4-Positive T-Lymphocytes - drug effects
Journal Article
Peptides, ISSN 0196-9781, 05/2017, Volume 91, pp. 40 - 48
We previously reported a series of novel endomorphin analogs with unnatural amino acid modifications. These analogs display good binding affinity and... 
Spinal antinociception | Antagonist | Endomorphin | Antibody | Dynorphin | CORD | MORPHINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | INVOLVEMENT | RELEASE | MU-OPIOID RECEPTOR | POTENT | PEPTIDOMIMETICS | ADMINISTERED ENDOMORPHIN-1 | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGY & PHARMACY | ANALGESIA | Analgesics, Opioid - antagonists & inhibitors | Naltrexone - analogs & derivatives | Opioid Peptides - pharmacology | Analgesics, Opioid - pharmacology | Male | Enkephalin, Leucine - administration & dosage | Opioid Peptides - administration & dosage | Receptors, sigma - antagonists & inhibitors | Dynorphins - chemistry | Enkephalin, Methionine - pharmacology | Pain - metabolism | Enkephalin, Leucine - antagonists & inhibitors | Naltrexone - pharmacology | Enkephalin, Methionine - chemistry | Pain - drug therapy | Enkephalin, Leucine - pharmacology | Analgesics, Opioid - chemistry | Antibodies - immunology | Enkephalin, Methionine - administration & dosage | Naltrexone - administration & dosage | Oligopeptides - chemistry | Enkephalin, Methionine - antagonists & inhibitors | Injections, Spinal | Oligopeptides - antagonists & inhibitors | Receptors, Opioid, kappa - antagonists & inhibitors | Receptors, Opioid, mu - antagonists & inhibitors | Dynorphins - antagonists & inhibitors | Enkephalin, Leucine - chemistry | Analgesia | Opioid Peptides - chemistry | Animals | Dynorphins - administration & dosage | Analysis of Variance | Analgesics, Opioid - administration & dosage | Naloxone - pharmacology | Opioid Peptides - antagonists & inhibitors | Narcotic Antagonists - pharmacology | Dynorphins - pharmacology | Mice | Oligopeptides - administration & dosage | Naloxone - administration & dosage | Oligopeptides - pharmacology | Pain Measurement | Fluorine - chemistry | Viral antibodies | Antibodies | Yuan (China) | Analysis
Journal Article
Alcoholism Clinical and Experimental Research, ISSN 0145-6008, 02/2010, Volume 34, Issue 2, pp. 214 - 222
Background:  Specialized hypothalamic systems that increase food intake might also increase ethanol intake. To test this possibility, morphine and... 
Paraventricular Nucleus | Hypothalamus | Ethanol | Rat | Opioids | ACCESS PARADIGM | BRAIN SITES | SUBSTANCE ABUSE | VENTRAL TEGMENTAL AREA | CIRCULATING TRIGLYCERIDES | ENERGY-BALANCE | ACCUMBENS SHELL | MESSENGER-RNA | OREXIGENIC PEPTIDES | OPIATE RECEPTORS | C-FOS EXPRESSION | Paraventricular Hypothalamic Nucleus - physiology | Receptors, Opioid - agonists | Narcotic Antagonists - administration & dosage | Enkephalin, Ala-MePhe-Gly- - administration & dosage | Alcohol Drinking - psychology | Analgesics, Opioid - pharmacology | Male | Enkephalin, Methionine - pharmacology | Ethanol - blood | Enkephalin, Methionine - administration & dosage | Microinjections | Morphine - pharmacology | Enkephalin, Ala-MePhe-Gly- - pharmacology | Rats | Enkephalin, Methionine - analogs & derivatives | Rats, Sprague-Dawley | Stimulation, Chemical | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - pharmacology | Eating - drug effects | Narcotics - administration & dosage | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Analgesics, Opioid - administration & dosage | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - administration & dosage | Drinking - drug effects | Narcotics - pharmacology | Central Nervous System Depressants - blood | Naloxone - administration & dosage | Morphine - administration & dosage | Brain | Alcohol, Denatured | Peptides | Analysis | Alcohol | Morphine | Glycine | PVN | rat | ethanol | hypothalamus | opioids
Journal Article
Journal Article
Journal Article
Journal of Peptide Science, ISSN 1075-2617, 02/2012, Volume 18, Issue 2, pp. 92 - 96
Dipeptidyl carboxypeptidase‐I is an enzyme involved in the biological degradation of enkephalins. It has been suggested that C‐terminal amidation of... 
biodegradation | enkephalin amide | antinociception |