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1. Full Text Candidate genes for temporal lobe epilepsy: a replication study
by Salzmann, Annick and Perroud, Nader and Crespel, Arielle and Lambercy, Carmen and Malafosse, Alain
Neurological sciences, ISSN 1590-1874, 12/2008, Volume 29, Issue 6, pp. 397 - 403
Neurology | Prodynorphin | Association | Medicine & Public Health | Apolipoprotein E | Interleukin 1 | Temporal lobe epilepsy | Genetics | Neurosurgery | Psychiatry | Neuroradiology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Genetic Predisposition to Disease - genetics | Genetic Testing | Protein Precursors - genetics | Gene Frequency | Humans | Epilepsy, Temporal Lobe - physiopathology | Genotype | Interleukin 1 Receptor Antagonist Protein - genetics | Epilepsy, Temporal Lobe - immunology | Interleukin-1beta - genetics | Case-Control Studies | Enkephalins - genetics | Interleukins - genetics | DNA Mutational Analysis | Apolipoproteins E - genetics | Epilepsy, Temporal Lobe - genetics | Genetic Markers - genetics | Adolescent | Adult | Polymorphism, Genetic - genetics | Interleukin-1alpha - genetics | Child | Cohort Studies | Genetic research | Interleukins | Apolipoproteins | Medical genetics | Index Medicus
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2. Full Text Expansion of Intronic GGCCTG Hexanucleotide Repeat in NOP56 Causes SCA36, a Type of Spinocerebellar Ataxia Accompanied by Motor Neuron Involvement
by Kobayashi, Hatasu and Abe, Koji and Matsuura, Tohru and Ikeda, Yoshio and Hitomi, Toshiaki and Akechi, Yuji and Habu, Toshiyuki and Liu, Wanyang and Okuda, Hiroko and Koizumi, Akio
American journal of human genetics, ISSN 0002-9297, 07/2011, Volume 89, Issue 1, pp. 121 - 130
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | General aspects. Genetic counseling | Neurology | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Medical genetics | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Haplotypes | Enkephalins - metabolism | Humans | Middle Aged | Spinocerebellar Ataxias - classification | Male | MicroRNAs - metabolism | Mutation, Missense | Lod Score | Motor Neurons - pathology | Enkephalins - genetics | Adult | Female | Nuclear Proteins - genetics | Spinocerebellar Ataxias - genetics | Introns - genetics | Protein Precursors - genetics | Amyotrophic Lateral Sclerosis - genetics | In Situ Hybridization, Fluorescence | Nuclear Proteins - metabolism | Spinocerebellar Ataxias - pathology | Protein Precursors - metabolism | Pedigree | Age of Onset | Aged | MicroRNAs - genetics | Alzheimer Disease - genetics | Cohort Studies | Genetics | Mutation | Medical screening | Neurological disorders | Fluorescence in situ hybridization | Index Medicus | Motor neurons | Neurodegenerative diseases | RNA | Transcription | Amyotrophic lateral sclerosis | RNA-binding protein | Genetic analysis | Family studies | miRNA | Open reading frames | Gene mapping | Alzheimer's disease | Linkage analysis | Report
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3. Full Text D2R striatopallidal neurons inhibit both locomotor and drug reward processes
by Durieux, Pierre F and Bearzatto, Bertrand and Guiducci, Stefania and Buch, Thorsten and Waisman, Ari and Zoli, Michele and Schiffmann, Serge N and d'Exaerde, Alban De Kerchove
Nature neuroscience, ISSN 1097-6256, 04/2009, Volume 12, Issue 4, pp. 393 - 395
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Diphtheria Toxin - pharmacology | Tyrosine 3-Monooxygenase - metabolism | Locomotion - genetics | Enkephalins - metabolism | Receptors, Dopamine D2 - deficiency | Conditioning, Operant - physiology | Receptors, Dopamine D2 - metabolism | Corpus Striatum - cytology | Enkephalins - genetics | Time Factors | Receptors, Adenosine A2 - genetics | Protein Binding - drug effects | Neurons - physiology | Neurons - drug effects | Locomotion - drug effects | Dopamine Uptake Inhibitors - pharmacology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Amphetamine - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | Glutamate Decarboxylase - genetics | Mice, Transgenic | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Autoradiography | Heparin-binding EGF-like Growth Factor | Reinforcement Schedule | Tyrosine 3-Monooxygenase - genetics | Animals | Globus Pallidus - cytology | Glutamate Decarboxylase - metabolism | Mice | Reward | Index Medicus
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4. Full Text Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice
by Min, So Yun and Kady, Jamie and Nam, Minwoo and Rojas-Rodriguez, Raziel and Berkenwald, Aaron and Kim, Jong Hun and Noh, Hye-Lim and Kim, Jason K and Cooper, Marcus P and Fitzgibbons, Timothy and Brehm, Michael A and Corvera, Silvia
Nature medicine, ISSN 1078-8956, 03/2016, Volume 22, Issue 3, pp. 312 - 318
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Enkephalins - metabolism | Humans | Middle Aged | Ion Channels - genetics | Male | RNA, Messenger - metabolism | Enkephalins - genetics | Mitochondrial Proteins - metabolism | Diet, High-Fat | Iodide Peroxidase - metabolism | Adipocytes, Brown - transplantation | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Oxygen Consumption | Apoptosis Regulatory Proteins - metabolism | Protein Precursors - metabolism | Mice | Iodide Peroxidase - genetics | Blood Glucose - metabolism | Integrin beta1 - genetics | Adipocytes, White - metabolism | Glucose Intolerance - metabolism | Proprotein Convertase 1 - genetics | Adipocytes, Brown - metabolism | Homeostasis | Mitochondrial Proteins - genetics | DNA-Binding Proteins - metabolism | Polymerase Chain Reaction | Apoptosis Regulatory Proteins - genetics | Adult | Female | Capillaries | Glucose Tolerance Test | Protein Precursors - genetics | Proprotein Convertase 1 - metabolism | Cell Transplantation | Adipocytes, White - transplantation | DNA-Binding Proteins - genetics | Obesity - metabolism | Integrin beta1 - metabolism | Interleukin-33 - genetics | Animals | Ion Channels - metabolism | Receptor, Platelet-Derived Growth Factor alpha - genetics | Adipocytes - metabolism | Fluorescent Antibody Technique | Interleukin-33 - metabolism | Adipocytes - transplantation | Aged | Glucose Clamp Technique | Uncoupling Protein 1 | Neovascularization, Physiologic | Adipose tissues | Physiological aspects | Genetic aspects | Research | Index Medicus | cytokine | human adipocyte | glucose | progenitors | adipokine | capillary | adrenergic | thermogenic adipose tissue | implant
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5. Full Text Aberrant methylation of NPY, PENK, and WIF1 as a promising marker for blood-based diagnosis of colorectal cancer
by Roperch, Jean-Pierre and Incitti, Roberto and Forbin, Solène and Bard, Floriane and Mansour, Hicham and Mesli, Farida and Baumgaertner, Isabelle and Brunetti, Francesco and Sobhani, Iradj
BMC cancer, ISSN 1471-2407, 12/2013, Volume 13, Issue 1, pp. 566 - 566
Epigenetic markers | QM-MSP | Circulating DNA methylation | Colorectal cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Neuropeptide Y - genetics | Case-Control Studies | Colorectal Neoplasms - diagnosis | DNA - blood | Enkephalins - genetics | DNA Methylation | Molecular Diagnostic Techniques | Aged, 80 and over | Female | Adenocarcinoma - genetics | Promoter Regions, Genetic | Protein Precursors - genetics | Colorectal Neoplasms - blood | Adenocarcinoma - blood | Repressor Proteins - genetics | Multiplex Polymerase Chain Reaction | Sequence Analysis, DNA | DNA - genetics | Adenocarcinoma - diagnosis | Adaptor Proteins, Signal Transducing - genetics | ROC Curve | Aged | Biomarkers, Tumor - genetics | Neoplasm Staging | Medical research | Epigenetic inheritance | Genetic markers | Medical examination | Medicine, Experimental | Diagnosis | Methylation | Blood | Index Medicus
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6. Full Text Revisiting disease genes based on whole-exome sequencing in consanguineous populations
by Shamia, Ahmed and Shaheen, Ranad and Sabbagh, Nouran and Almoisheer, Agaadir and Halees, Anason and Alkuraya, Fowzan S
Human genetics, ISSN 0340-6717, 9/2015, Volume 134, Issue 9, pp. 1029 - 1034
Human Genetics | Gene Function | Molecular Medicine | Biomedicine | Metabolic Diseases | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Lipoproteins - genetics | Humans | Infant | Male | Exome | Enkephalins - genetics | ATP-Binding Cassette Transporters - genetics | Serine Endopeptidases - genetics | Cell Cycle Proteins - genetics | Adult | Child | Intracellular Signaling Peptides and Proteins - genetics | Claudins - genetics | Protein Precursors - genetics | Connexins - genetics | Repressor Proteins - genetics | Amino Acid Transport Systems, Neutral - genetics | Homozygote | Phenotype | Symporters - genetics | Adolescent | Alleles | TRPM Cation Channels - genetics | Consanguinity | Genome, Human | Genome-Wide Association Study - methods | ATP Binding Cassette Transporter, Sub-Family G, Member 5 | Genes | Genomics | Index Medicus
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7. Full Text Methylation of ELOVL2 gene as a new epigenetic marker of age
by Garagnani, Paolo and Bacalini, Maria G and Pirazzini, Chiara and Gori, Davide and Giuliani, Cristina and Mari, Daniela and Di Blasio, Anna M and Gentilini, Davide and Vitale, Giovanni and Collino, Sebastiano and Rezzi, Serge and Castellani, Gastone and Capri, Miriam and Salvioli, Stefano and Franceschi, Claudio
Aging cell, ISSN 1474-9718, 12/2012, Volume 11, Issue 6, pp. 1132 - 1134
FHL 2 | DNA methylation | aging | biomarker | PENK | ELOVL 2 | Aging | Biomarker | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Transcription Factors - blood | Oligonucleotide Array Sequence Analysis | Protein Precursors - blood | Epigenesis, Genetic | Humans | Middle Aged | Male | Acetyltransferases - genetics | Enkephalins - blood | Enkephalins - genetics | DNA Methylation | Muscle Proteins - blood | Aging - genetics | Fetal Blood - chemistry | Aged, 80 and over | Adult | Female | Child | Protein Precursors - genetics | Genetic Markers | Transcription Factors - genetics | Aging - blood | Muscle Proteins - genetics | LIM-Homeodomain Proteins - genetics | LIM-Homeodomain Proteins - blood | Adolescent | CpG Islands | Aged | Genome, Human | Acetyltransferases - blood | Genetic research | Methylation | Genes | Index Medicus | Cord blood | biomarkers | epigenetics | CpG islands
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8. Full Text Clinical significance of promoter methylation status of tumor suppressor genes in circulating DNA of pancreatic cancer patients
by Singh, Nidhi and Rashid, Sumaira and Rashid, Safoora and Dash, Nihar Ranjan and Gupta, Surabhi and Saraya, Anoop
Journal of cancer research and clinical oncology, ISSN 0171-5216, 04/2020, Volume 146, Issue 4, pp. 897 - 907
Life Sciences & Biomedicine | Oncology | Science & Technology | Pancreatic Neoplasms - blood | Promoter Regions, Genetic | Protein Precursors - genetics | Circulating Tumor DNA - genetics | Humans | Middle Aged | Male | Pancreatic Neoplasms - genetics | C-Reactive Protein - genetics | Pancreatitis, Chronic - genetics | Ubiquitin Thiolesterase - genetics | Nerve Tissue Proteins - genetics | Case-Control Studies | Carcinoma, Pancreatic Ductal - genetics | Carcinoma, Pancreatic Ductal - blood | Cell Differentiation - genetics | Enkephalins - genetics | DNA Methylation | Osteonectin - genetics | Pancreatitis, Chronic - blood | Female | Circulating Tumor DNA - blood | Genes, Tumor Suppressor | Index Medicus
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9. Full Text Mutations in rare ataxia genes are uncommon causes of sporadic cerebellar ataxia
by Fogel, Brent L and Lee, Ji Yong and Lane, Jessica and Wahnich, Amanda and Chan, Sandy and Huang, Alden and Osborn, Greg E and Klein, Eric and Mamah, Catherine and Perlman, Susan and Geschwind, Daniel H and Coppola, Giovanni
Movement disorders, ISSN 0885-3185, 03/2012, Volume 27, Issue 3, pp. 442 - 446
dominant genetic conditions | recessive genetic conditions | cerebellar ataxia | copy number variation | spinocerebellar ataxia | Recessive genetic conditions | Dominant genetic conditions | Copy number variation | Cerebellar ataxia | Spinocerebellar ataxia | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Genetic Predisposition to Disease - genetics | Genetic Testing | Protein Precursors - genetics | Lamin Type B - genetics | Humans | Middle Aged | Transglutaminases - genetics | Male | Mutation - genetics | Nerve Tissue Proteins - genetics | Enkephalins - genetics | Heat-Shock Proteins - genetics | Magnetic Resonance Imaging | Phenotype | Cerebellar Ataxia - genetics | Databases, Bibliographic - statistics & numerical data | Adult | Female | RNA Helicases - genetics | Aged | Nuclear Proteins - genetics | Index Medicus | Spinocerebellar Ataxia | Dominant Genetic Conditions | Recessive Genetic Conditions | Cerebellar Ataxia | Copy Number Variation
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10. Full Text κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction
by Butelman, Eduardo R and Yuferov, Vadim and Kreek, Mary Jeanne
Trends in neurosciences (Regular ed.), ISSN 0166-2236, 2012, Volume 35, Issue 10, pp. 587 - 596
Neurology | prescription opioids | dynorphin | heroin | κ-opioid receptor | cocaine | addiction | Cocaine | Addiction | Prescription opioids | Heroin | Dynorphin | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Mood disorders | Biological and medical sciences | General aspects. Models. Methods | Depression | Medical sciences | Behavior, Addictive - drug therapy | Recurrence | Genetic Predisposition to Disease - genetics | Receptors, Opioid, kappa - antagonists & inhibitors | Protein Precursors - genetics | Behavior, Addictive - genetics | Adaptation, Biological - genetics | Humans | Receptors, Opioid, kappa - agonists | Drug Discovery - methods | Dynorphins - physiology | Adaptation, Biological - physiology | Polymorphism, Genetic | Receptors, Opioid, kappa - physiology | Enkephalins - genetics | Animals | Narcotic Antagonists - therapeutic use | Narcotic Antagonists - pharmacology | Behavior, Addictive - physiopathology | Street Drugs - pharmacology | Disease Models, Animal | Index Medicus | Drug addiction | Opioid receptors | Withdrawal | Opioid receptors (type mu) | epigenetics | Reviews | Plasticity | Reinforcement | Anxiety | Genetic factors | kappa-opioid receptor
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