X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (11713) 11713
Book Review (670) 670
Publication (528) 528
Book Chapter (29) 29
Conference Proceeding (12) 12
Dissertation (10) 10
Book / eBook (7) 7
Magazine Article (3) 3
Newsletter (3) 3
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (11278) 11278
animals (9946) 9946
rats (5737) 5737
male (5568) 5568
neurosciences (3204) 3204
enkephalins - metabolism (2826) 2826
humans (2353) 2353
mice (2013) 2013
enkephalin (1882) 1882
female (1817) 1817
rats, sprague-dawley (1552) 1552
brain - metabolism (1550) 1550
pharmacology & pharmacy (1550) 1550
receptors, opioid - metabolism (1537) 1537
rats, inbred strains (1372) 1372
biochemistry & molecular biology (1332) 1332
enkephalins - pharmacology (1329) 1329
enkephalin, methionine - metabolism (1181) 1181
enkephalins - genetics (1133) 1133
naloxone - pharmacology (1118) 1118
in vitro techniques (1086) 1086
brain (1045) 1045
protein precursors - genetics (987) 987
kinetics (979) 979
enkephalin, ala-mephe-gly (976) 976
immunohistochemistry (952) 952
receptors, opioid, mu - metabolism (917) 917
enkephalin, leucine - metabolism (914) 914
morphine - pharmacology (903) 903
morphine (877) 877
dose-response relationship, drug (868) 868
amino acid sequence (804) 804
neurons - metabolism (803) 803
molecular sequence data (785) 785
rat (781) 781
endocrinology & metabolism (780) 780
endorphins - metabolism (770) 770
protein precursors - metabolism (762) 762
enkephalin, leucine - analogs & derivatives (756) 756
enkephalins (753) 753
analgesics, opioid - pharmacology (749) 749
rna, messenger - metabolism (748) 748
beta-endorphin (741) 741
peptides (731) 731
rats, wistar (708) 708
narcotic antagonists - pharmacology (706) 706
enkephalin, ala-mephe-gly- - pharmacology (700) 700
receptors, opioid - drug effects (681) 681
corpus striatum - metabolism (680) 680
guinea pigs (675) 675
time factors (672) 672
enkephalin, methionine - pharmacology (649) 649
cells, cultured (616) 616
neurons (616) 616
met-enkephalin (611) 611
receptors, opioid, delta - metabolism (588) 588
enkephalin, methionine - analogs & derivatives (548) 548
opioid receptors (547) 547
rat-brain (546) 546
radioimmunoassay (532) 532
enkephalin, d-penicillamine (531) 531
receptors, opioid, mu - agonists (531) 531
naltrexone - pharmacology (523) 523
enkephalin, leucine - pharmacology (519) 519
spinal cord - metabolism (516) 516
enkephalins - biosynthesis (514) 514
receptors (514) 514
substance p - metabolism (511) 511
analgesics - pharmacology (504) 504
neurons - drug effects (489) 489
cattle (484) 484
analgesia (483) 483
brain - drug effects (480) 480
expression (478) 478
endorphins - pharmacology (474) 474
dynorphin (469) 469
in situ hybridization (467) 467
substance-p (449) 449
autoradiography (431) 431
receptors, opioid, mu (423) 423
naltrexone - analogs & derivatives (422) 422
cell line (421) 421
oligopeptides - pharmacology (417) 417
structure-activity relationship (414) 414
messenger-rna (413) 413
binding, competitive (403) 403
opioids (403) 403
enkephalin, leucine-2-alanine (402) 402
opioid peptides (395) 395
receptors, opioid, delta (393) 393
chromatography, high pressure liquid (377) 377
dopamine (376) 376
ligands (368) 368
neuropeptides (368) 368
substance p (367) 367
gene expression (365) 365
receptors, opioid - physiology (365) 365
corpus striatum - drug effects (363) 363
dynorphins - metabolism (361) 361
opiates (360) 360
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (11282) 11282
Russian (239) 239
Chinese (77) 77
French (48) 48
Japanese (45) 45
German (17) 17
Polish (10) 10
Italian (6) 6
Spanish (5) 5
Ukrainian (4) 4
Czech (2) 2
Hungarian (2) 2
Romanian (2) 2
Swedish (2) 2
Bulgarian (1) 1
Dutch (1) 1
Hebrew (1) 1
Korean (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Medicine, ISSN 1078-8956, 03/2016, Volume 22, Issue 3, pp. 312 - 318
Uncoupling protein 1 (UCP1) is highly expressed in brown adipose tissue, where it generates heat by uncoupling electron transport from ATP production. UCP1 is... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | WHITE | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADULT HUMANS | BROWN ADIPOSE-TISSUE | IDENTIFICATION | CELL BIOLOGY | OBESITY | GENE | INFLAMMATION | EXPRESSION | Enkephalins - metabolism | Humans | Middle Aged | Ion Channels - genetics | Male | RNA, Messenger - metabolism | Enkephalins - genetics | Mitochondrial Proteins - metabolism | Diet, High-Fat | Iodide Peroxidase - metabolism | Adipocytes, Brown - transplantation | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Oxygen Consumption | Apoptosis Regulatory Proteins - metabolism | Protein Precursors - metabolism | Mice | Iodide Peroxidase - genetics | Blood Glucose - metabolism | Integrin beta1 - genetics | Adipocytes, White - metabolism | Glucose Intolerance - metabolism | Proprotein Convertase 1 - genetics | Adipocytes, Brown - metabolism | Homeostasis | Mitochondrial Proteins - genetics | DNA-Binding Proteins - metabolism | Polymerase Chain Reaction | Apoptosis Regulatory Proteins - genetics | Adult | Female | Capillaries | Glucose Tolerance Test | Protein Precursors - genetics | Proprotein Convertase 1 - metabolism | Cell Transplantation | Adipocytes, White - transplantation | DNA-Binding Proteins - genetics | Obesity - metabolism | Integrin beta1 - metabolism | Interleukin-33 - genetics | Animals | Ion Channels - metabolism | Receptor, Platelet-Derived Growth Factor alpha - genetics | Adipocytes - metabolism | Fluorescent Antibody Technique | Interleukin-33 - metabolism | Adipocytes - transplantation | Aged | Glucose Clamp Technique | Uncoupling Protein 1 | Neovascularization, Physiologic | Adipose tissues | Physiological aspects | Genetic aspects | Research | Index Medicus | cytokine | human adipocyte | glucose | progenitors | adipokine | capillary | adrenergic | thermogenic adipose tissue | implant
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2010, Volume 38, Issue 1, pp. 168 - 176
This study investigated the role of a multispecific organic anion transporter, Oatp1a4/ Slco1a4 , in drug transport across the blood-brain barrier. In vitro... 
LOCALIZATION | INVOLVEMENT | POLYPEPTIDE-2 | PENETRATION | PHARMACOLOGY & PHARMACY | RAT-BRAIN | OATP2 | BCRP/ABCG2 | 17-BETA-ESTRADIOL-D-17-BETA-GLUCURONIDE | CANCER RESISTANCE PROTEIN | P-GLYCOPROTEIN | Fluorobenzenes - pharmacokinetics | Gene Expression - genetics | Pyrimidines - blood | Humans | Ion Pumps - genetics | Fluorobenzenes - administration & dosage | Quinolines - administration & dosage | Pyrimidines - metabolism | Brain - metabolism | Quinolines - pharmacokinetics | Choroid Plexus - blood supply | ATP-Binding Cassette Transporters - genetics | Ochratoxins - administration & dosage | Cell Membrane - metabolism | Cerebral Cortex - drug effects | Capillaries - metabolism | Fluorobenzenes - metabolism | Tetrahydroisoquinolines - pharmacology | Organic Cation Transport Proteins - metabolism | Pravastatin - metabolism | Liver - metabolism | Rosuvastatin Calcium | Sulfonamides - pharmacokinetics | Blood-Brain Barrier - metabolism | Mice, Knockout | Brain - drug effects | Taurocholic Acid - administration & dosage | Pravastatin - administration & dosage | Enkephalin, D-Penicillamine (2,5)- - administration & dosage | Pyrimidines - pharmacokinetics | Mice | Kinetics | Organic Cation Transport Proteins - genetics | Pravastatin - pharmacokinetics | Sulfonamides - administration & dosage | Quinolines - blood | Digoxin - metabolism | Taurocholic Acid - metabolism | Choroid Plexus - metabolism | Taurocholic Acid - blood | Ochratoxins - pharmacokinetics | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Ochratoxins - metabolism | Cerebral Cortex - metabolism | Organic Anion Transporters - metabolism | Brain - blood supply | Sulfonamides - blood | Organic Anion Transporters - genetics | Transfection | Fluorobenzenes - blood | Enkephalin, D-Penicillamine (2,5)- - pharmacokinetics | Recombinant Proteins - metabolism | Cell Line | Pyrimidines - administration & dosage | Mice, Inbred C57BL | Recombinant Proteins - genetics | Blood-Brain Barrier - drug effects | Digoxin - pharmacokinetics | Quinolines - metabolism | Taurocholic Acid - pharmacokinetics | Liver - blood supply | Pharmaceutical Preparations - metabolism | Animals | Digoxin - administration & dosage | Enkephalin, D-Penicillamine (2,5)- - metabolism | Acridines - pharmacology | Sulfonamides - metabolism | Index Medicus
Journal Article
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 01/2016, Volume 310, Issue 1, pp. R41 - R54
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 06/2010, Volume 88, Issue 6, pp. 682 - 691
To evaluate potential mechanisms of clinical hepatotoxicity, 4 endothelin receptor antagonists (ERAs) were examined for substrate activity and inhibition of... 
Hepatic transport | BSEP | Endothelin | Transporter substrate | Pulmonary artery hypertension | Endothelin receptor antagonists | OATP | PHARMACOKINETIC INTERACTION | PHYSIOLOGY | pulmonary artery hypertension | RAT HEPATOCYTES | PULMONARY ARTERIAL-HYPERTENSION | SALT EXPORT PUMP | transporter substrate | HEPATIC-UPTAKE | endothelin receptor antagonists | CLINICAL-PRACTICE GUIDELINES | endothelin | CYCLOSPORINE-A | THERAPY | BILIARY-EXCRETION | KETOCONAZOLE | PHARMACOLOGY & PHARMACY | hepatic transport | Antihypertensive Agents - pharmacology | Estradiol - analogs & derivatives | Taurocholic Acid - metabolism | Humans | Middle Aged | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Male | Thiophenes - metabolism | Antihypertensive Agents - metabolism | Hepatocytes - metabolism | Pyridazines - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Organic Anion Transporters - metabolism | Pyrimidines - metabolism | Young Adult | Phenylpropionates - metabolism | Symporters - antagonists & inhibitors | ATP-Binding Cassette Transporters - metabolism | Adult | Female | Pyridazines - metabolism | Biological Transport - drug effects | Cell Culture Techniques | Endothelin Receptor Antagonists | Hepatocytes - drug effects | Estradiol - metabolism | Organic Anion Transporters - antagonists & inhibitors | Isoxazoles - metabolism | Organic Anion Transporters, Sodium-Dependent - antagonists & inhibitors | Cells, Cultured | Thiophenes - pharmacology | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Symporters - metabolism | Isoxazoles - pharmacology | Phenylpropionates - pharmacology | ATP Binding Cassette Subfamily B Member 11 | Enkephalin, D-Penicillamine (2,5)- - metabolism | Adolescent | Sulfonamides - metabolism | Aged | Multidrug Resistance-Associated Proteins - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | Cell receptors | Genetic aspects | Research | Diagnosis | Properties | Health aspects | Liver cells | Pulmonary hypertension | Studies | Drugs | Pathology | Medical treatment | Liver | Index Medicus
Journal Article
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 06/2014, Volume 39, Issue 11, pp. 1796 - 1809
Activation of mu‐opioid receptor ( MOR ) disinhibits dopaminergic neurons in the ventral tegmental area ( VTA ) through inhibition of γ‐aminobutyric acid (... 
mouse | bed nucleus of the stria terminalis | ventral tegmental area | GABA | immunohistochemistry | dopaminergic neuron | ergic neuron | Immunohistochemistry | GABAergic neuron | Dopaminergic neuron | Mouse | Bed nucleus of the stria terminalis | Ventral tegmental area | NONDOPAMINERGIC NEURONS | KNOCKOUT MICE | SUBSTANTIA-NIGRA | NEUROSCIENCES | MU-OPIOID RECEPTORS | DOPAMINE NEURONS | VOLUME TRANSMISSION | GLUTAMATERGIC NEURONS | GABA-CONTAINING NEURONS | RAT-BRAIN | Neural Inhibition | Enkephalins - metabolism | gamma-Aminobutyric Acid - metabolism | Septal Nuclei - physiology | GABAergic Neurons - physiology | Ventral Tegmental Area - cytology | Septal Nuclei - cytology | Ventral Tegmental Area - physiology | RNA, Messenger - metabolism | Enkephalins - genetics | Septal Nuclei - metabolism | Dopaminergic Neurons - metabolism | Dopaminergic Neurons - physiology | GABAergic Neurons - metabolism | Vesicular Glutamate Transport Protein 2 - genetics | Dendrites - metabolism | Protein Precursors - genetics | Receptors, Opioid, mu - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Vesicular Glutamate Transport Protein 2 - metabolism | Cells, Cultured | Axons - metabolism | Protein Precursors - metabolism | Protein Transport | Neuropil - metabolism | Animals | Receptors, GABA-A - genetics | Ventral Tegmental Area - metabolism | Mice | Receptors, GABA-A - metabolism | Receptors, Opioid, mu - genetics | RNA | Glutamate | Neurons | Index Medicus
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 11/2010, Volume 285, Issue 47, pp. 36625 - 36634
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 02/2009, Volume 34, Issue 3, pp. 775 - 785
Stress and anxiety are mainly regulated by amygdala and hypothalamic circuitries involving several neurotransmitter systems and providing physiological... 
Hypothalamic-pituitary-adrenal axis | Paraventricular | κ-opioid receptor | Amygdala | Prodynorphin knockout | Stress | CORTICOTROPIN-RELEASING HORMONE | hypothalamic-pituitary-adrenal axis | stress | amygdala | PSYCHIATRY | BEHAVIOR | NEUROSCIENCES | MICE LACKING | NEUROPEPTIDE-Y | kappa-opioid receptor | prodynorphin knockout | OPIOID-SYSTEM | MESSENGER-RNA | IMPAIRED STRESS-RESPONSE | ANXIOLYTIC-LIKE | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | SUBSTANCE-P | paraventricular nucleus | Naltrexone - analogs & derivatives | Enkephalins - metabolism | Mesencephalon - metabolism | Brain Stem - metabolism | Dynorphins - physiology | Male | Neuropeptide Y - genetics | Mice, Knockout - metabolism | Raphe Nuclei - metabolism | Morphinans | Neuropeptide Y - metabolism | Enkephalins - genetics | Naltrexone - pharmacology | Protein Precursors - physiology | Female | Enkephalins - physiology | Corticosterone - blood | Neuropeptides - genetics | Anxiety - metabolism | Neuropeptide Y - physiology | Exploratory Behavior | Receptors, Opioid, kappa - antagonists & inhibitors | Protein Precursors - genetics | Mice, Inbred C57BL | Receptors, Opioid, kappa - agonists | Amygdala - metabolism | Anxiety - physiopathology | Neuropeptides - metabolism | Guanidines | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - pharmacology | Corticotropin-Releasing Hormone - metabolism | Protein Precursors - metabolism | Animals | Hypothalamus - metabolism | Maze Learning | Mice | Stress, Psychological - physiopathology | Index Medicus | hypothalamic–pituitary–adrenal axis
Journal Article
Pain, ISSN 0304-3959, 07/2014, Volume 155, Issue 7, pp. 1293 - 1302
Lack of interleukin-17 leads to a modulated micro-environment and amelioration of mechanical hypersensitivity after peripheral nerve injury in mice.... 
Nerve injury | Animal model | Inflammation | Interleukin-17 | Neuropathic pain | CELLS | BRAIN-INJURY | SPINAL-CORD | NEUROSCIENCES | BETA-ENDORPHIN | CLINICAL NEUROLOGY | INFILTRATION | IMMUNE | BEHAVIORAL HYPERSENSITIVITY | HOST-DEFENSE | ANESTHESIOLOGY | INFLAMMATORY RESPONSE | Tumor Necrosis Factor-alpha - metabolism | Sciatic Nerve - injuries | Neuralgia - genetics | Peripheral Nerve Injuries - immunology | Enkephalins - metabolism | Interleukin-17 - immunology | Neuralgia - metabolism | Interleukin-13 - immunology | Behavior, Animal | beta-Endorphin - metabolism | Neuralgia - immunology | Interleukin-2 - immunology | Interleukin-1beta - metabolism | Peripheral Nerve Injuries - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Dynorphins - metabolism | Interleukin-6 - metabolism | Macrophages - immunology | Cytokines - immunology | Disease Models, Animal | Interleukin-2 - metabolism | Nociception | Central Nervous System Sensitization - immunology | Cytokines - metabolism | Hyperalgesia - metabolism | Mice, Inbred C57BL | Neutrophils - immunology | Interleukin-17 - genetics | Interleukin-1beta - immunology | Inflammation - immunology | Interleukin-13 - metabolism | Mice, Knockout | Hyperalgesia - immunology | Animals | Hyperalgesia - genetics | Interleukin-6 - immunology | Inflammation - genetics | T-Lymphocytes - immunology | Mice | Central Nervous System Sensitization - genetics | Peripheral Nerve Injuries - genetics | Interleukin-10 - immunology | Peroxidase - metabolism | Interleukins | Allergy | Allergic reaction | Index Medicus
Journal Article