Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2015, Volume 58, Issue 9, pp. 3682 - 3692
The increasing dissemination of carbapenemases in Gram-negative bacteria has threatened the clinical usefulness of the beta-lactam class of antimicrobials. A...
CHEMISTRY, MEDICINAL | SUBSTRATE | COMPLEXES | RESISTANCE | HYDROLYSIS | ACYL | TRANSITION-STATE ANALOG | STRUCTURE-BASED DESIGN | ENTEROBACTERIACEAE | Stereoisomerism | Drug Resistance, Bacterial | Crystallography, X-Ray | Boronic Acids - chemistry | Structure-Activity Relationship | Gram-Negative Bacteria - isolation & purification | beta-Lactamase Inhibitors - pharmacokinetics | Microbial Sensitivity Tests | Carbapenems - pharmacology | Heterocyclic Compounds, 1-Ring - chemistry | Heterocyclic Compounds, 1-Ring - pharmacology | Anti-Bacterial Agents - chemistry | Bacterial Proteins - antagonists & inhibitors | Heterocyclic Compounds, 1-Ring - pharmacokinetics | Models, Molecular | Rats | beta-Lactamase Inhibitors - pharmacology | Drug Synergism | Gram-Negative Bacteria - enzymology | Gram-Negative Bacteria - drug effects | Animals | Anti-Bacterial Agents - pharmacokinetics | Boronic Acids - pharmacokinetics | beta-Lactamases | Anti-Bacterial Agents - pharmacology | Mice | beta-Lactamase Inhibitors - chemistry | Boronic Acids - pharmacology
CHEMISTRY, MEDICINAL | SUBSTRATE | COMPLEXES | RESISTANCE | HYDROLYSIS | ACYL | TRANSITION-STATE ANALOG | STRUCTURE-BASED DESIGN | ENTEROBACTERIACEAE | Stereoisomerism | Drug Resistance, Bacterial | Crystallography, X-Ray | Boronic Acids - chemistry | Structure-Activity Relationship | Gram-Negative Bacteria - isolation & purification | beta-Lactamase Inhibitors - pharmacokinetics | Microbial Sensitivity Tests | Carbapenems - pharmacology | Heterocyclic Compounds, 1-Ring - chemistry | Heterocyclic Compounds, 1-Ring - pharmacology | Anti-Bacterial Agents - chemistry | Bacterial Proteins - antagonists & inhibitors | Heterocyclic Compounds, 1-Ring - pharmacokinetics | Models, Molecular | Rats | beta-Lactamase Inhibitors - pharmacology | Drug Synergism | Gram-Negative Bacteria - enzymology | Gram-Negative Bacteria - drug effects | Animals | Anti-Bacterial Agents - pharmacokinetics | Boronic Acids - pharmacokinetics | beta-Lactamases | Anti-Bacterial Agents - pharmacology | Mice | beta-Lactamase Inhibitors - chemistry | Boronic Acids - pharmacology
Journal Article
Analytical Chemistry, ISSN 0003-2700, 08/2015, Volume 87, Issue 15, pp. 7738 - 7745
The alarming rate at which antibiotic resistance is occurring in human pathogens causes a pressing need for improved diagnostic technologies aimed at rapid...
LABEL-FREE | CHEMISTRY, ANALYTICAL | PNA | PERFORMANCE | IN-SITU HYBRIDIZATION | IMPEDANCE SPECTROSCOPY | INFECTION | IDENTIFICATION | DNA HYBRIDIZATION | PROBE | EMERGENCE | Enterobacteriaceae - enzymology | Electrochemical Techniques | Enterobacteriaceae Infections - microbiology | Humans | Enterobacteriaceae - genetics | Bacterial Typing Techniques - methods | Anti-Bacterial Agents - therapeutic use | Carbapenems - pharmacology | beta-Lactamases - genetics | Time Factors | Enterobacteriaceae - drug effects | Protein Array Analysis | Anti-Bacterial Agents - pharmacology | Drug Resistance, Multiple, Bacterial - genetics | Enterobacteriaceae - classification | Enterobacteriaceae Infections - drug therapy | Electrochemical analysis | Usage | Enterobacter | Beta lactamases | Research | Carbapenems | Enterobacteriaceae
LABEL-FREE | CHEMISTRY, ANALYTICAL | PNA | PERFORMANCE | IN-SITU HYBRIDIZATION | IMPEDANCE SPECTROSCOPY | INFECTION | IDENTIFICATION | DNA HYBRIDIZATION | PROBE | EMERGENCE | Enterobacteriaceae - enzymology | Electrochemical Techniques | Enterobacteriaceae Infections - microbiology | Humans | Enterobacteriaceae - genetics | Bacterial Typing Techniques - methods | Anti-Bacterial Agents - therapeutic use | Carbapenems - pharmacology | beta-Lactamases - genetics | Time Factors | Enterobacteriaceae - drug effects | Protein Array Analysis | Anti-Bacterial Agents - pharmacology | Drug Resistance, Multiple, Bacterial - genetics | Enterobacteriaceae - classification | Enterobacteriaceae Infections - drug therapy | Electrochemical analysis | Usage | Enterobacter | Beta lactamases | Research | Carbapenems | Enterobacteriaceae
Journal Article
Biochemistry, ISSN 0006-2960, 06/2015, Volume 54, Issue 21, pp. 3370 - 3380
OXA-163 and OXA-48 are closely related class D beta-lactamases that exhibit different substrate profiles. OXA-163 hydrolyzes oxyimino-cephalosporins,...
OXA-10 | STRUCTURE REFINEMENT | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEDIATED RESISTANCE | LYSINE | CARBAPENEMASES | CARBOXYLATION | MOLECULAR-BASIS | BINDING | ENTEROBACTERIACEAE | Iodides - pharmacology | Carbapenems - metabolism | Catalytic Domain | Enterobacter cloacae - enzymology | Enterobacteriaceae Infections - microbiology | Humans | Enzyme Inhibitors - pharmacology | Anti-Bacterial Agents - metabolism | Klebsiella Infections - microbiology | Enterobacter cloacae - chemistry | beta-Lactamases - chemistry | Ceftazidime - metabolism | Klebsiella pneumoniae - enzymology | Protein Conformation | Molecular Docking Simulation | Klebsiella pneumoniae - chemistry | Cephalosporins - metabolism | β-lactam antibiotics | oxacillinase | serine β-lactamases | Gram-negative bacteria | carbapenemase | antibiotic resistance
OXA-10 | STRUCTURE REFINEMENT | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEDIATED RESISTANCE | LYSINE | CARBAPENEMASES | CARBOXYLATION | MOLECULAR-BASIS | BINDING | ENTEROBACTERIACEAE | Iodides - pharmacology | Carbapenems - metabolism | Catalytic Domain | Enterobacter cloacae - enzymology | Enterobacteriaceae Infections - microbiology | Humans | Enzyme Inhibitors - pharmacology | Anti-Bacterial Agents - metabolism | Klebsiella Infections - microbiology | Enterobacter cloacae - chemistry | beta-Lactamases - chemistry | Ceftazidime - metabolism | Klebsiella pneumoniae - enzymology | Protein Conformation | Molecular Docking Simulation | Klebsiella pneumoniae - chemistry | Cephalosporins - metabolism | β-lactam antibiotics | oxacillinase | serine β-lactamases | Gram-negative bacteria | carbapenemase | antibiotic resistance
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 1900, Volume 137, Issue 24, pp. 7608 - 7611
The para-aminobenzoic acid-containing peptide albicidin is a pathogenicity factor synthesized by Xanthomonas albilineans in infections of sugar cane. Albicidin...
LEAF SCALD DISEASE | GENE | PANTOEA-DISPERSA | BIOCONTROL | XANTHOMONAS-ALBILINEANS | INHIBITOR | CHEMISTRY, MULTIDISCIPLINARY | Xanthomonas - metabolism | Enterobacteriaceae Infections - microbiology | Humans | Drug Resistance, Bacterial | Organic Chemicals - metabolism | Anti-Bacterial Agents - metabolism | Hydrolysis | Organic Chemicals - pharmacology | Pantoea - enzymology | Anti-Bacterial Agents - pharmacology | Serine Endopeptidases - metabolism | Enterobacteriaceae Infections - drug therapy | Pantoea - drug effects | Chemical properties | Research | Catalysis | Peptides | Chemical synthesis
LEAF SCALD DISEASE | GENE | PANTOEA-DISPERSA | BIOCONTROL | XANTHOMONAS-ALBILINEANS | INHIBITOR | CHEMISTRY, MULTIDISCIPLINARY | Xanthomonas - metabolism | Enterobacteriaceae Infections - microbiology | Humans | Drug Resistance, Bacterial | Organic Chemicals - metabolism | Anti-Bacterial Agents - metabolism | Hydrolysis | Organic Chemicals - pharmacology | Pantoea - enzymology | Anti-Bacterial Agents - pharmacology | Serine Endopeptidases - metabolism | Enterobacteriaceae Infections - drug therapy | Pantoea - drug effects | Chemical properties | Research | Catalysis | Peptides | Chemical synthesis
Journal Article
Medical Microbiology and Immunology, ISSN 0300-8584, 5/2011, Volume 200, Issue 2, pp. 137 - 141
Carbapenems are important last-line antibiotics for the treatment of hospital infections. Enterobacteriaceae (such as Klebsiella pneumoniae or Escherichia...
Medical Microbiology | Emerging pathogen | Biomedicine | Immunology | PCR | Resistance, synthetic gene, positive control | MICROBIOLOGY | IMMUNOLOGY | Enterobacteriaceae - enzymology | DNA, Bacterial - isolation & purification | Humans | Polymerase Chain Reaction - methods | Microbial Sensitivity Tests | Reference Standards | Carbapenems - pharmacology | DNA, Bacterial - genetics | beta-Lactamases - genetics | Time Factors | Sensitivity and Specificity | Enterobacteriaceae - drug effects | DNA, Bacterial - analysis | beta-Lactamases - chemical synthesis | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - genetics
Medical Microbiology | Emerging pathogen | Biomedicine | Immunology | PCR | Resistance, synthetic gene, positive control | MICROBIOLOGY | IMMUNOLOGY | Enterobacteriaceae - enzymology | DNA, Bacterial - isolation & purification | Humans | Polymerase Chain Reaction - methods | Microbial Sensitivity Tests | Reference Standards | Carbapenems - pharmacology | DNA, Bacterial - genetics | beta-Lactamases - genetics | Time Factors | Sensitivity and Specificity | Enterobacteriaceae - drug effects | DNA, Bacterial - analysis | beta-Lactamases - chemical synthesis | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - genetics
Journal Article
Acta pathologica et microbiologica Scandinavica, ISSN 0365-5555, 1954, Volume 34, Issue 2, pp. 102 - 114
Journal Article
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, ISSN 0372-8110, 12/1964, Volume 195, Issue 1, p. 61
Journal Article
Laboratornoe delo, ISSN 0023-6748, 1965, Volume 11, p. 677
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Bulletin de la Societe de chimie biologique, ISSN 0037-9042, 1965, Volume 47, Issue 7, p. 1526
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Annales de l'Institut Pasteur de Lille, ISSN 0073-8573, 1965, Volume 16, p. 175
Journal Article
Rinsho byori. The Japanese journal of clinical pathology, ISSN 0047-1860, 11/1965, Volume 13, Issue 11, p. 637
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Annales de l'Institut Pasteur, ISSN 0020-2444, 01/1966, Volume 110, Issue 1, p. 126
Journal Article
Angewandte Chemie International Edition in English, ISSN 0570-0833, 02/1966, Volume 5, Issue 2, pp. 198 - 210
The outer cell surface of Enterobacteriaceae, i.e. the cell wall, consist of a rigid structure (murein) on which additional proteins, lipids, and...
Bacterial mutants | Polysaccharides | Lipopolysaccharides | CHEMISTRY, MULTIDISCIPLINARY | Cell Wall | Enterobacteriaceae - chemically induced | Histocytochemistry - cytology | Polysaccharides, Bacterial | Enterobacteriaceae - cytology | Salmonella - cytology
Bacterial mutants | Polysaccharides | Lipopolysaccharides | CHEMISTRY, MULTIDISCIPLINARY | Cell Wall | Enterobacteriaceae - chemically induced | Histocytochemistry - cytology | Polysaccharides, Bacterial | Enterobacteriaceae - cytology | Salmonella - cytology
Journal Article
Folia Microbiologica, ISSN 0015-5632, 09/1966, Volume 11, Issue 5, pp. 358 - 363
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MICROBIOLOGY | Rabbits | Animals | Enterobacteriaceae - drug effects | Lymphocytes - enzymology | Anti-Bacterial Agents - pharmacology | Hot Temperature | In Vitro Techniques | Leukocytes - enzymology | Cathepsins - pharmacology | Endotoxins - pharmacology | Macrophages - enzymology
Journal Article
The American journal of medical technology, ISSN 0002-9335, 03/1966, Volume 32, Issue 2, pp. 135 - 139
Journal Article
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, ISSN 0372-8110, 05/1966, Volume 200, Issue 1, pp. 49 - 55
Galactosidases - analysis | Enterobacteriaceae - enzymology | Escherichia coli - isolation & purification | Salmonella - isolation & purification | Shigella - classification | Enterobacteriaceae Infections - classification | Bacteriological Techniques | Enterobacteriaceae - isolation & purification | Shigella - isolation & purification | Salmonella - classification | Escherichia coli - classification
Journal Article
L'igiene moderna, ISSN 0019-1655, 11/1966, Volume 59, Issue 11, p. 637
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L'igiene moderna, ISSN 0019-1655, 11/1966, Volume 59, Issue 11, p. 631
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Technical bulletin of the Registry of Medical Technologists, ISSN 0097-0654, 11/1966, Volume 36, Issue 11, pp. 292 - 293
Journal Article
Antimicrobial agents and chemotherapy, 1967, Volume 7, p. 271
Journal Article
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