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Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 20, pp. 2457 - 2464
Highlights • We developed and tested a new oral ETEC vaccine in mice, alone and with an adjuvant. • The vaccine contains E. coli overexpressing CFA/I, CS3, CS5... 
Allergy and Immunology | Vaccine | Mucosal immunity | Immune responses | ETEC | dmLT | Colonization factors | DmLT | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | DIARRHEA | PREVENTION | IMMUNOLOGY | VIBRIO-CHOLERAE | CELL CHOLERA VACCINE | TRAVELERS | CONSTRUCTION | ENTEROTOXIGENIC ESCHERICHIA-COLI | INTRANASAL IMMUNIZATION | ANTIBODY-RESPONSES | Immunity, Mucosal - immunology | Adjuvants, Immunologic - administration & dosage | Immunoglobulin G - blood | Escherichia coli Infections - prevention & control | Antigens, Bacterial - immunology | Antigens, Bacterial - genetics | Intestines - immunology | Enterotoxins - immunology | Escherichia coli Proteins - administration & dosage | Immunoglobulin G - immunology | Cholera Toxin - immunology | Bacterial Toxins - genetics | Female | Escherichia coli Proteins - immunology | Immunoglobulin G - analysis | Mutant Proteins - immunology | Fimbriae Proteins - immunology | Cholera Toxin - administration & dosage | Antibody Formation - immunology | Vaccines, Inactivated - genetics | Administration, Oral | Bacterial Toxins - immunology | Escherichia coli Infections - microbiology | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Mutant Proteins - administration & dosage | Enterotoxins - administration & dosage | Vaccines, Inactivated - adverse effects | Enterotoxins - genetics | Vaccines, Inactivated - immunology | Animals | Escherichia coli Vaccines - adverse effects | Fimbriae Proteins - genetics | Vaccines, Inactivated - administration & dosage | Cholera Toxin - genetics | Immunoglobulin A - immunology | Escherichia coli Proteins - genetics | Immunoglobulin A - blood | Bacterial Toxins - administration & dosage | Escherichia coli Infections - immunology | Escherichia coli Vaccines - genetics | Mice | Mice, Inbred BALB C | Escherichia coli Vaccines - immunology | Immunoglobulin A - analysis | Antigens | Safety and security measures | Analysis | Escherichia coli | Bacteria | Vaccines | Contamination | Proteins | Studies | Immunology | E coli | Rodents | Index Medicus | Basic Medicine | Medicinska grundvetenskaper
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 12, pp. 4555 - 4564
Globally, enterotoxigenic Escherichia coli (ETEC) is a leading cause of childhood and travelers' diarrhea, for which an effective vaccine is needed. Prevalent... 
COLONIZATION FACTOR ANTIGENS | HEAT-LABILE TOXIN | INFECTIOUS DISEASES | IMMUNOGENICITY | TRAVELERS DIARRHEA | DNA VACCINE | CFA/I FIMBRIAE | INFANT MOUSE MODEL | DOUBLE-BLIND | IMMUNOLOGY | VIRULENCE | SUBUNIT | Escherichia coli Infections - mortality | Milk - chemistry | Dose-Response Relationship, Immunologic | Immune Sera - chemistry | Escherichia coli Infections - prevention & control | Immunoglobulin A - biosynthesis | Adhesins, Bacterial - genetics | Escherichia coli Infections - genetics | Antibodies, Bacterial - biosynthesis | Escherichia coli Proteins - administration & dosage | Immunoglobulin G - biosynthesis | Cattle | Female | Mice, Inbred DBA | Escherichia coli Proteins - immunology | Fimbriae, Bacterial - immunology | Milk - immunology | Enterotoxigenic Escherichia coli - genetics | Fimbriae Proteins - immunology | Gene Expression | Adhesins, Bacterial - administration & dosage | Enterotoxigenic Escherichia coli - drug effects | Fimbriae, Bacterial - chemistry | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Pregnancy | Animals | Fimbriae Proteins - genetics | Survival Analysis | Vaccines, Attenuated | Escherichia coli Proteins - genetics | Immunization, Passive | Escherichia coli Infections - immunology | Escherichia coli Vaccines - genetics | Fimbriae Proteins - administration & dosage | Mice | Adhesins, Bacterial - immunology | Escherichia coli Vaccines - immunology | Microbial Immunity and Vaccines
Journal Article
by Yu, M and Qi, R and Chen, C and Yin, J and Ma, S and Shi, W and Wu, Y and Ge, J and Jiang, Y and Tang, L and Xu, Y and Li, Y
Journal of Applied Microbiology, ISSN 1364-5072, 02/2017, Volume 122, Issue 2, pp. 506 - 515
AimsThe aims of this study were to develop an effective oral vaccine against enterotoxigenic Escherichia coli (ETEC) infection and to design new and more... 
heat‐labile enterotoxin A subunit | Lactobacillus casei | fimbriae adhesin FaeG | heat‐labile enterotoxin B subunit | immunogenicity | heat-labile enterotoxin A subunit | heat-labile enterotoxin B subunit | VIRUS | PROTECTION | VACCINE | MICROBIOLOGY | MUCOSAL | IMMUNIZATION | EPITOPE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IMMUNE-RESPONSES | PIGLETS | SUBUNIT | ANTIGEN | Adjuvants, Immunologic - administration & dosage | Escherichia coli Infections - prevention & control | Immunity, Mucosal | Adhesins, Escherichia coli - genetics | Lymphocytes - immunology | Enterotoxins - immunology | Escherichia coli Proteins - administration & dosage | Swine | Adhesins, Escherichia coli - immunology | Female | Escherichia coli Infections - veterinary | Escherichia coli Proteins - immunology | Lactobacillus casei - genetics | Fimbriae, Bacterial | Specific Pathogen-Free Organisms | Administration, Oral | Bacterial Toxins - immunology | Swine Diseases - immunology | Lymphocytes - cytology | Swine Diseases - prevention & control | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Enterotoxins - administration & dosage | Animals | Bacterial Toxins - administration & dosage | Escherichia coli Infections - immunology | Mice | Mice, Inbred BALB C | Escherichia coli Vaccines - immunology | Enterotoxigenic Escherichia coli - classification | Toxins | Bacterial infections | Vaccines | E coli | Microbiology
Journal Article
Infection and Immunity, ISSN 0019-9567, 01/2013, Volume 81, Issue 1, pp. 259 - 270
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
MOLECULAR CHARACTERIZATION | INTESTINAL COLONIZATION | OUTER-MEMBRANE VESICLES | VACCINE CANDIDATES | MURINE MODEL | INFECTIOUS DISEASES | HEAT-LABILE ENTEROTOXIN | TOXIN DELIVERY | IMMUNE-RESPONSES | CYCLIC DI-GMP | IMMUNOLOGY | MAMMALIAN-CELLS | Epithelial Cells - metabolism | Gene Expression - genetics | Adhesins, Bacterial - genetics | Humans | Virulence | Intestines - metabolism | Transcriptome - immunology | Cyclic GMP - immunology | Promoter Regions, Genetic - genetics | Intestines - immunology | Host-Pathogen Interactions - immunology | DNA-Binding Proteins - metabolism | Adhesins, Bacterial - metabolism | Receptors, Cyclic AMP - metabolism | Escherichia coli Infections - genetics | Cyclic GMP - analogs & derivatives | Enterotoxigenic Escherichia coli - pathogenicity | Gene Expression - immunology | Antigens, Surface - metabolism | Escherichia coli Proteins - immunology | Receptors, Cyclic AMP - genetics | Enterotoxigenic Escherichia coli - genetics | Caco-2 Cells | DNA-Binding Proteins - immunology | Antigens, Surface - genetics | Escherichia coli Infections - microbiology | Escherichia coli Proteins - metabolism | Escherichia coli Infections - metabolism | Transcriptome - genetics | DNA-Binding Proteins - genetics | Enterotoxigenic Escherichia coli - immunology | Intestines - microbiology | Cyclic GMP - metabolism | Host-Pathogen Interactions - genetics | Epithelial Cells - immunology | Epithelial Cells - microbiology | Cyclic GMP - genetics | Cell Line, Tumor | Escherichia coli Proteins - genetics | Transcription, Genetic - immunology | Escherichia coli Infections - immunology | Promoter Regions, Genetic - immunology | Transcription, Genetic - genetics | Adhesins, Bacterial - immunology | Receptors, Cyclic AMP - immunology | Antigens, Surface - immunology | Cellular Microbiology | Pathogen-Host Cell Molecular Interactions
Journal Article
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 11, pp. 1458 - 1463
Highlights ► Piglets orally inoculated with an E. coli strain expressing a holotoxin-like adhesin–toxoid fusion antigen 1FaeG-FedF-LTA2 :5LTB were protected... 
Allergy and Immunology | K88 (F4) | Live attenuated vaccine | Heat-labile toxin (LT) | F18, 987P | Enterotoxigenic E. coli (ETEC) | Diarrhea | Porcine post-weaning diarrhea (PWD) | ANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | HEAT-LABILE ENTEROTOXIN | COLIBACILLOSIS | PREVALENCE | MODEL | IMMUNOLOGY | VIRULENCE GENES | ADHERENCE | FIMBRIAE | CHOLERA-TOXIN | Escherichia coli Infections - prevention & control | Diarrhea - prevention & control | Neutralization Tests | Vaccines, Synthetic - immunology | Antibodies, Bacterial - analysis | Bacterial Toxins - antagonists & inhibitors | Serum - immunology | Adhesins, Bacterial - metabolism | Vaccines, Synthetic - adverse effects | Intestinal Mucosa - immunology | Swine | Vaccines, Attenuated - administration & dosage | Escherichia coli Infections - veterinary | Enterotoxigenic Escherichia coli - genetics | Antibodies, Bacterial - blood | Administration, Oral | Intestine, Small - microbiology | Vaccines, Synthetic - genetics | Bacterial Load | Swine Diseases - prevention & control | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Vaccines, Attenuated - immunology | Animals | Escherichia coli Vaccines - adverse effects | Escherichia coli Vaccines - genetics | Vaccines, Synthetic - administration & dosage | Escherichia coli Vaccines - immunology | Vaccines, Attenuated - adverse effects | Vaccines, Attenuated - genetics | Phosphates | Monoclonal antibodies | Immunization | Biological products | Escherichia coli
Journal Article