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Journal Article
Journal Article
PLoS pathogens, ISSN 1553-7366, 10/2010, Volume 6, Issue 10, pp. e1001163 - e1001163
In a screen for RNA mutagen resistance, we isolated a high fidelity RNA dependent RNA polymerase (RdRp) variant of Coxsackie virus B3 (CVB3). Curiously, this... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Transcription, Genetic - drug effects | Antiviral Agents - pharmacology | Humans | Mutagens - pharmacology | Amiloride - adverse effects | Amiloride - analogs & derivatives | Cercopithecus aethiops | Templates, Genetic | Mutagenesis - drug effects | RNA - genetics | Animals | Enterovirus - genetics | RNA, Viral - genetics | Genetic Variation - drug effects | Antiviral Agents - adverse effects | Base Sequence | Amiloride - pharmacology | HeLa Cells | Transcription, Genetic - genetics | DNA-Directed RNA Polymerases - metabolism | RNA, Viral - drug effects | Vero Cells | RNA - metabolism | Amiloride | Gene mutations | Genetic variation | Properties | Identification and classification | Health aspects | RNA polymerases | Index Medicus | Fidelity | Pathogens | RNA viruses | Ions | Genomes | DNA-directed RNA polymerase | Amino acid substitution | Disease resistance | Mutagenesis | Mutagens | Proofreading | Cations | Magnesium | Mutation | RNA | Antiviral Agents | Enterovirus | Genetic Variation | Life Sciences | Microbiology and Parasitology | DNA-Directed RNA Polymerases | RNA, Viral | Transcription, Genetic | Hela Cells | Proteins | Medical research | Viruses | Genetic diversity | RNA polymerase | Experiments | Crystal structure
Journal Article
Scientific reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, pp. 22002 - 22002
When retinoic acid-inducible gene 1 protein (RIG-I)-like receptors sense viral dsRNA in the cytosol, RIG-I and melanoma differentiation-associated gene 5... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Enterovirus A, Human - genetics | RNA, Small Interfering - genetics | Interferon-Induced Helicase, IFIH1 - genetics | Humans | NF-kappa B - immunology | Vesiculovirus - immunology | eIF-2 Kinase - immunology | NF-KappaB Inhibitor alpha - genetics | Influenza A Virus, H3N2 Subtype - genetics | Interferon Type I - immunology | Luciferases - genetics | RNA, Viral - genetics | RNA, Small Interfering - immunology | DEAD Box Protein 58 - genetics | Luciferases - immunology | HEK293 Cells | Pyruvate Carboxylase - immunology | Adaptor Proteins, Signal Transducing - immunology | Vesiculovirus - genetics | Cytokines - genetics | Genes, Reporter | Cytokines - immunology | eIF-2 Kinase - genetics | Signal Transduction | Enterovirus A, Human - immunology | Gene Expression Regulation | Pyruvate Carboxylase - genetics | NF-KappaB Inhibitor alpha - immunology | Hepatocytes - immunology | Immunity, Innate | Influenza A Virus, H3N2 Subtype - immunology | Pyruvate Carboxylase - antagonists & inhibitors | Interferon-Induced Helicase, IFIH1 - immunology | DEAD Box Protein 58 - immunology | Animals | NF-kappa B - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Hepatocytes - virology | Interferon Type I - genetics | RNA, Viral - immunology | RNA viruses | eIF-2 kinase | Phosphorylation | Immune response | Cytokines | Myxovirus resistance proteins | Double-stranded RNA | Melanoma | Pyruvic acid | Viruses | Biotin | Inflammation | Kinases | Cytosol | Pyruvate carboxylase | Nuclear transport | Proteins | Stomatitis | Mitochondria | Protein kinase | Transcription activation | Antiviral activity | Interferon | Retinoic acid | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e109755 - e109755
... and tracrRNA, can guide Cas9 endonuclease to target a DNA sequence by design, resulting in site-specific genetic modifications [2], [3]. These landmark studies have led... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Gene Targeting - methods | Endonucleases - genetics | Epithelial Cells - metabolism | KCNQ1 Potassium Channel - genetics | RNA, Guide - genetics | RNA, Guide - metabolism | KCNQ1 Potassium Channel - metabolism | Molecular Sequence Data | Endonucleases - metabolism | Kidney - metabolism | Cell Nucleus - metabolism | RNA, Messenger - administration & dosage | Plasmids - genetics | Protein Phosphatase 1 - genetics | Epithelial Cells - cytology | Genetic Engineering - methods | Amino Acid Sequence | Mutagenesis, Site-Directed | Microinjections | Animals, Genetically Modified | CRISPR-Associated Proteins - genetics | RNA, Messenger - genetics | Bacterial Proteins - genetics | Kidney - cytology | Protein Phosphatase 1 - metabolism | Animals | Cell Nucleus - genetics | CRISPR-Associated Proteins - metabolism | Mesocricetus - genetics | STAT2 Transcription Factor - genetics | Bacterial Proteins - metabolism | Cytosol - metabolism | STAT2 Transcription Factor - metabolism | Plasmids - administration & dosage | RNA | Genetically modified organisms | Animal models | Viruses | Infections | Genomes | mRNA | Design | Gene targeting | Rodents | Life sciences | Potassium channels (voltage-gated) | Deoxyribonucleic acid--DNA | Stat2 protein | CRISPR | Injection | Mammals | Hamsters | Somatic cells | Plasmids | Adenoviruses | Stem cells | KCNQ1 protein | Genetic engineering | Gene loci | Mutation | Laboratory animals | Viral infections | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PloS one, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, pp. e0130378 - e0130378
Acute Respiratory Infections (ARIs) are responsible for considerable morbidity and mortality worldwide. Documentation of respiratory specimens can help for an... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Middle Aged | Reagent Kits, Diagnostic - standards | Child, Preschool | Infant | Rhinovirus - isolation & purification | Parechovirus - isolation & purification | Respirovirus - genetics | Gram-Negative Bacteria - isolation & purification | Gram-Positive Bacteria - genetics | Respiratory Tract Infections - microbiology | Adenoviridae - isolation & purification | Human bocavirus - genetics | Enterovirus - genetics | Adenoviridae - genetics | Adult | Gram-Negative Bacteria - genetics | Respiratory Tract Infections - virology | Child | Coronavirus - isolation & purification | Cytomegalovirus - genetics | Cytomegalovirus - isolation & purification | Acute Disease | Parechovirus - genetics | Respiratory Syncytial Viruses - isolation & purification | Enterovirus - isolation & purification | Human bocavirus - isolation & purification | Respiratory Tract Infections - diagnosis | Multiplex Polymerase Chain Reaction - standards | Respiratory Syncytial Viruses - genetics | Adolescent | Orthomyxoviridae - genetics | Coronavirus - genetics | Gram-Positive Bacteria - isolation & purification | Respirovirus - isolation & purification | Aged | Orthomyxoviridae - isolation & purification | Rhinovirus - genetics | Comparative analysis | Health aspects | Mortality | Influenza | Lung diseases | Multiplexing | Pathogens | Microbiology | Laboratories | Health risks | Life assessment | Viruses | Infections | Nucleic acids | Medical diagnosis | Disease control | Morbidity | Molecular chains | Virology | Hospitals | Respiratory diseases | Bacteria | Influenza A | Diagnostic systems | Diagnosis | Public health | Viral infections | Index Medicus | Life Sciences | Human health and pathology | Infectious diseases | Biochemistry, Molecular Biology
Journal Article
PloS one, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, pp. e0147832 - e0147832
Journal Article
PloS one, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e102866 - e102866
Journal Article