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1. Full Text Virology, epidemiology, pathogenesis, and control of enterovirus 71
by Solomon, Tom, Prof and Lewthwaite, Penny, MRCP and Perera, David, PhD and Cardosa, Mary Jane, Prof and McMinn, Peter, Prof and Ooi, Mong How, MRCP
Lancet Infectious Diseases, The, ISSN 1473-3099, 2010, Volume 10, Issue 11, pp. 778 - 790
Summary First isolated in California, USA, in 1969, enterovirus 71 (EV71) is a major public health issue across the Asia-Pacific region and beyond. The virus,... 
Infectious Disease | INFECTIOUS DISEASES | ACUTE FLACCID PARALYSIS | GENETIC-ANALYSIS | MOUTH-DISEASE | NEUROGENIC PULMONARY-EDEMA | POLIOMYELITIS-LIKE DISEASE | MOLECULAR EPIDEMIOLOGY | CENTRAL-NERVOUS-SYSTEM | BRAIN-STEM ENCEPHALITIS | CLINICAL-FEATURES | NEUROLOGIC INVOLVEMENT | Enterovirus Infections - prevention & control | California - epidemiology | Humans | Asia - epidemiology | Enterovirus A, Human - isolation & purification | Enterovirus Infections - epidemiology | Pacific Islands - epidemiology | Enterovirus Infections - virology | Hand, Foot and Mouth Disease - pathology | Hand, Foot and Mouth Disease - epidemiology | Hand, Foot and Mouth Disease - complications | Enterovirus A, Human - pathogenicity | Enterovirus Infections - pathology | Viral Vaccines - immunology | Hand, Foot and Mouth Disease - virology | Epidemiology | Health aspects | Coxsackievirus infections
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2. Full Text Motor coordination and balance measurements reveal differential pathogenicity of currently spreading enterovirus 71 strains in human SCARB2 transgenic mice
by Chen, Mei-Feng and Shih, Shin-Ru
Journal of General Virology, ISSN 0022-1317, 12/2016, Volume 97, Issue 12, pp. 3243 - 3247
Enterovirus 71 (EV71) has caused large-scale epidemics with neurological complications in the Asia-Pacific region. The C4a and B5 strains are the two major... 
Enterovirus 71 | Monocyte chemoattractant protein-1 | Motor coordination | Human SCARB2 transgenic mice | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ENCEPHALITIS | DISEASE | INJURY | INFECTION | MODEL | EPIDEMIC | Enterovirus Infections - metabolism | Lysosome-Associated Membrane Glycoproteins - metabolism | Humans | Virulence | Enterovirus A, Human - physiology | Genotype | Mice, Transgenic | Enterovirus Infections - physiopathology | Motor Activity | Mice, Inbred ICR | Animals | Enterovirus Infections - virology | Receptors, Scavenger - genetics | Enterovirus Infections - genetics | Lysosome-Associated Membrane Glycoproteins - genetics | Chemokine CCL2 - metabolism | Mice | Enterovirus A, Human - pathogenicity | Receptors, Scavenger - metabolism
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3. Full Text Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71
by Shimojima, Masayuki and Shimizu, Hiroyuki and Miyamura, Tatsuo and Nishimura, Yorihiro and Wakita, Takaji and Tano, Yoshio
Nature Medicine, ISSN 1078-8956, 07/2009, Volume 15, Issue 7, pp. 794 - 797
Enterovirus 71 (EV71) is a major causative agent of hand, foot and mouth disease (HFMD), a common febrile disease occurring mainly in young children. Although... 
ENCEPHALOMYELITIS | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | TAIWAN | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | CELL BIOLOGY | EVOLUTION | MEDIATED EXPRESSION CLONING | CENTRAL-NERVOUS-SYSTEM | CYNOMOLGUS MONKEYS | INFECTION | MOLECULAR-BASIS | Membrane Glycoproteins - analysis | Cell Line | Membrane Glycoproteins - physiology | Animals | Virus Replication | Jurkat Cells | Humans | Enterovirus A, Human - physiology | Mice | Receptors, Virus - analysis | Enterovirus A, Human - pathogenicity | Receptors, Virus - physiology | Receptors | Physiological aspects | Causes of | Viruses | Genetic aspects | Glycoproteins | Research | Coxsackievirus infections | Protein binding | Proteins | Leucocytes | Epidemiology
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4. Full Text Pretreatment with a heat-killed probiotic modulates monocyte chemoattractant protein-1 and reduces the pathogenicity of influenza and enterovirus 71 infections
by Chen, M.-F and Weng, K.-F and Huang, S.-Y and Liu, Y.-C and Tseng, S.-N and Ojcius, D.M and Shih, S.-R
Mucosal Immunology, ISSN 1933-0219, 01/2017, Volume 10, Issue 1, pp. 215 - 227
It has been proposed that inactivated probiotics may modulate the host immune system and contribute to mitigation of viral infections. This study demonstrated... 
A VIRUS | MCP-1 | VIRUS-INFECTION | LIPOTEICHOIC ACID | IMMUNE-RESPONSES | NEURONAL DEATH | LACTOBACILLUS-PARACASEI | MICE | IMMUNOLOGY | ENTEROCOCCUS-FAECALIS FK-23 | HOUSE-DUST MITE | Enterococcus faecalis - immunology | Probiotics - administration & dosage | Receptors, CCR2 - genetics | Immunomodulation | Humans | Mice, Inbred C57BL | Cells, Cultured | Enterovirus A, Human - immunology | Male | Hot Temperature | Mice, Knockout | Orthomyxoviridae - immunology | Animals | Enterovirus Infections - immunology | Chemokine CCL2 - metabolism | Mice | Enterovirus A, Human - pathogenicity | Orthomyxoviridae - pathogenicity | Orthomyxoviridae Infections - immunology | Index Medicus
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5. Full Text Non‐polio Enterovirus detection with acute flaccid paralysis: A systematic review
by Suresh, Sneha and Forgie, Sarah and Robinson, Joan
Journal of Medical Virology, ISSN 0146-6615, 01/2018, Volume 90, Issue 1, pp. 3 - 7
Acute flaccid paralysis (AFP), as defined by the World Health Organization (WHO), is characterized by an acute onset of limb weakness. In the post‐polio era,... 
acute flaccid paralysis (AFP) | pathogenesis (nervous system) | systematic review | VIROLOGY | MYELITIS | Enterovirus A, Human - genetics | Enterovirus D, Human - genetics | Humans | Child, Preschool | Male | Phylogeny | Nucleic Acid Amplification Techniques | Enterovirus A, Human - isolation & purification | Enterovirus Infections - epidemiology | Feces - virology | Enterovirus Infections - virology | Enterovirus Infections - complications | Adult | Enterovirus B, Human - genetics | Female | Enterovirus A, Human - pathogenicity | Child | Paraplegia - epidemiology | Enterovirus A, Human - immunology | Serogroup | Enterovirus D, Human - immunology | Paraplegia - etiology | Poliovirus | Enterovirus D, Human - pathogenicity | Asia - epidemiology | Paraplegia - virology | Adolescent | Enterovirus D, Human - isolation & purification | Enterovirus B, Human - immunology | Enterovirus B, Human - isolation & purification | Enterovirus B, Human - pathogenicity | Case studies | Paralysis | Poliomyelitis | Public health | Surveillance | Case reports | Serotypes | Viruses | Vaccines
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6. Full Text UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication
by Huang, Peng-Nien and Jheng, Jia-Rong and Arnold, Jamie J and Wang, Jen-Ren and Cameron, Craig E and Shih, Shin-Ru
PLoS Pathogens, ISSN 1553-7366, 05/2017, Volume 13, Issue 5, p. e1006375
Positive-strand RNA virus infections can induce the stress-related unfolded protein response (UPR) in host cells. This study found that enterovirus A71 (EVA71)... 
PICORNAVIRUS GENOME REPLICATION | PROTEIN | POLYMERASE | MICROBIOLOGY | VPG URIDYLYLATION | POLIOVIRUS INFECTION | VIROLOGY | HEPATITIS-C VIRUS | MOUTH-DISEASE | POLIOMYELITIS-LIKE DISEASE | ENDOPLASMIC-RETICULUM | NUCLEAR FACTOR | PARASITOLOGY | Endoplasmic Reticulum - enzymology | Enterovirus A, Human - genetics | Amino Acid Sequence | Cell Proliferation | Cell Survival | Virus Replication - genetics | Enterovirus A, Human - physiology | RNA, Viral - analysis | Viral Proteins - genetics | Unfolded Protein Response | Viral Proteins - metabolism | Mice, Knockout | Host-Pathogen Interactions | Glucosyltransferases - metabolism | Animals | RNA, Viral - genetics | Virulence - genetics | Cell Line, Tumor | Mice | Enterovirus A, Human - pathogenicity | Glucosyltransferases - genetics | Epidemics | Biotechnology | Membranes | Growth rate | Transcription | Laboratories | Virulence | Science | Viruses | Infections | Biochemistry | Defense mechanisms | Glucose | Proteins | Hepatitis | Protein folding | Research centers | Glucosyltransferase | Pathogens | RNA viruses | Dengue fever | Glycoprotein | Glycoproteins | RNA polymerase | Ribonucleic acid--RNA | Virology | Pathogenicity | Medicine | Polymerase | Enteroviruses | West Nile virus | Replication | Molecular biology | Endoplasmic reticulum | Viral infections | RNA | Ribonucleic acid
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7. Viral and host factors that contribute to pathogenicity of enterovirus 71
by Huang, Hsing-I and Weng, Kuo-Feng and Shih, Shin-Ru
Future Microbiology, ISSN 1746-0913, 04/2012, Volume 7, Issue 4, pp. 467 - 479
The single-stranded RNA virus enterovirus 71 (EV71), which belongs to the Picornaviridae family, has caused epidemics worldwide, particularly in the... 
tropism | pathogenesis | apoptosis | ITAF | EV71 | immunity | SELECTIN GLYCOPROTEIN LIGAND-1 | APOPTOTIC CELL-DEATH | MICROBIOLOGY | BRAIN-STEM ENCEPHALITIS | ENDOPLASMIC-RETICULUM STRESS | COXSACKIEVIRUS A24 VARIANT | INTERFERON-GAMMA | MOUTH-DISEASE | POLIOMYELITIS-LIKE DISEASE | CENTRAL-NERVOUS-SYSTEM | NF-KAPPA-B | Host-Pathogen Interactions | Animals | Enterovirus Infections - virology | Enterovirus Infections - immunology | Humans | Enterovirus A, Human - immunology | Enterovirus A, Human - physiology | Enterovirus A, Human - pathogenicity | Viral Tropism | Immunity
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8. Full Text Clinically isolated enterovirus A71 subgenogroup C4 strain with lethal pathogenicity in 14-day-old mice and the application as an EV-A71 mouse infection model
by Xu, Yi and Xu, Yuhua and Ma, Shuzhi and Zhu, Limeng and Huang, Zhiqiu and Chen, Liyun and Yin, Haibin and Peng, Tao and Wang, Yi
Antiviral Research, ISSN 0166-3542, 01/2017, Volume 137, pp. 67 - 75
The Enterovirus A71 (EV-A71) subgenogroup C4 is prevalent in China. EV-A71 causes hand, foot and mouth disease (HFMD) in children and may lead to severe... 
Vaccine | Mouse infection model | Enterovirus A71 (EV-A71) | Primary isolate | VIROLOGY | PROTECTION | VP1 | ENHANCEMENT | ADAPTATION | DISEASE | PHARMACOLOGY & PHARMACY | CYNOMOLGUS MONKEYS | Enterovirus A, Human - genetics | Age Factors | Humans | Virulence | Enterovirus A, Human - isolation & purification | Hand, Foot and Mouth Disease - prevention & control | Enterovirus Infections - virology | Enterovirus Infections - immunology | China | Enterovirus A, Human - classification | Enterovirus Infections - therapy | Enterovirus A, Human - pathogenicity | Child | Hand, Foot and Mouth Disease - virology | Disease Models, Animal | Enterovirus Infections - prevention & control | Hand, Foot and Mouth Disease - immunology | Hand, Foot and Mouth Disease - therapy | Viral Vaccines - administration & dosage | Vaccines, Inactivated - immunology | Animals | Vaccines, Inactivated - administration & dosage | Virus Replication | Immunization, Passive | Mice | Mutation | Viral Vaccines - immunology | Medical colleges | Antiviral agents | Nervous system diseases | Genomics | Therapeutics | Virulence (Microbiology) | Coxsackievirus infections | Homeopathy | Materia medica and therapeutics
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9. Full Text Human enterovirus 71 and hand, foot and mouth disease
by WONG, S. S. Y and YIP, C. C. Y and LAU, S. K. P and YUEN, K. Y
Epidemiology and Infection, ISSN 0950-2688, 8/2010, Volume 138, Issue 8, pp. 1071 - 1089
Hand, foot and mouth disease (HFMD) is generally a benign febrile exanthematous childhood disease caused by human enteroviruses. The route of transmission is... 
Epidemics | Infectious diseases | Microbiology | Disease outbreaks | Viruses | REVIEW ARTICLE | Enterovirus | Infections | Hand foot and mouth disease | Epidemiology | Virology | foot and mouth disease | enterovirus 71 | enterovirus | Hand | SCAVENGER RECEPTOR BI | INFECTIOUS DISEASES | SELECTIN GLYCOPROTEIN LIGAND-1 | TREATED DRINKING-WATER | BRAIN-STEM ENCEPHALITIS | REPUBLIC-OF-CHINA | PULMONARY-EDEMA | LETHAL ENTEROVIRUS-71 | HIGH-DENSITY-LIPOPROTEIN | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | POLYMERASE-CHAIN-REACTION | MOLECULAR EPIDEMIOLOGY | Enterovirus A, Human - genetics | Asia - epidemiology | Pacific Islands - epidemiology | Disease Outbreaks | Humans | Enterovirus A, Human - physiology | Hand, Foot and Mouth Disease - epidemiology | Enterovirus A, Human - pathogenicity | Hand, Foot and Mouth Disease - virology
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10. Full Text Association of viral replication capacity with the pathogenicity of enterovirus 71
by Sun, Le-le and Wang, Jia-Kun and Wang, Zhi-Yu and Cui, Xiao-qing and Hao, Shu-Bin and Li, Jing and Zhao, Li and Yuan, Xiao-jing and Wen, Hong-ling and Yu, Xue-jie
Virus Research, ISSN 0168-1702, 08/2014, Volume 189, pp. 1 - 7
Enterovirus 71 (EV71) is a major cause of hand-foot-and-mouth disease, which is associated with fatal neurological disease. The mechanism of EV71 pathogenesis... 
Pathogenicity | Replication | EV71 | STRAINS | TAIWAN | CHINA | HAND | CHILDREN | FOOT | VIROLOGY | MOUTH-DISEASE | INFECTION | OUTBREAK | Immunohistochemistry | Cell Line | Humans | Virulence | Enterovirus A, Human - physiology | Enterovirus A, Human - growth & development | Mice, Inbred ICR | Animals | Enterovirus Infections - virology | Animal Structures - virology | Virus Replication | Female | Enterovirus A, Human - pathogenicity | Enterovirus Infections - pathology | Disease Models, Animal | Virus diseases | Quality control equipment
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11. Full Text Scavenger receptor B2 is a cellular receptor for enterovirus 71
by Yamayoshi, Seiya and Yamashita, Yasuko and Li, Jifen and Hanagata, Nobutaka and Minowa, Takashi and Takemura, Taro and Koike, Satoshi
Nature Medicine, ISSN 1078-8956, 07/2009, Volume 15, Issue 7, pp. 798 - 801
Enterovirus 71 (EV71) belongs to human enterovirus species A of the genus Enterovirus within the family Picornaviridae(1). EV71, together with coxsackievirus... 
SYSTEM | MEDICINE, RESEARCH & EXPERIMENTAL | PUBLIC-HEALTH | BIOCHEMISTRY & MOLECULAR BIOLOGY | HAND | FOOT | CELL BIOLOGY | EVOLUTION | POLIOVIRUS RECEPTOR | MOUTH-DISEASE | INFECTION | MEMBRANE-PROTEINS | OUTBREAK | Rhabdomyosarcoma - virology | Humans | Gene Expression Profiling | Receptors, Virus - analysis | Lysosome-Associated Membrane Glycoproteins - physiology | Receptors, Virus - physiology | Animals | Receptors, Scavenger - genetics | Receptors, Scavenger - physiology | Lysosome-Associated Membrane Glycoproteins - genetics | Receptors, Scavenger - analysis | Mice | Enterovirus A, Human - pathogenicity | Lysosome-Associated Membrane Glycoproteins - analysis | Viral antibodies | Cell receptors | Physiological aspects | Antibodies | Research | Enterovirus diseases | Risk factors | Proteins | Viruses | Cellular biology | Epidemiology | Binding sites
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12. Full Text Understanding Enterovirus 71 Neuropathogenesis and Its Impact on Other Neurotropic Enteroviruses
by Ong, Kien Chai and Wong, Kum Thong
Brain Pathology, ISSN 1015-6305, 09/2015, Volume 25, Issue 5, pp. 614 - 624
Enterovirus A71 (EV‐A71) belongs to the species group A in the Enterovirus genus within the Picornaviridae family. EV‐A71 usually causes self‐limiting hand,... 
neurotropism | CNS | enterovirus | Enterovirus A71 | neuropathogenesis | BRAIN-STEM ENCEPHALITIS | PATHOLOGY | COXSACKIEVIRUS A16 | VIRAL REPLICATION | NEUROSCIENCES | CLINICAL NEUROLOGY | MR-IMAGING FINDINGS | ACUTE FLACCID PARALYSIS | MOUTH-DISEASE | MOUSE MODEL | CENTRAL-NERVOUS-SYSTEM | CYNOMOLGUS MONKEYS | TRANSGENIC MICE | Coxsackievirus Infections - pathology | Enterovirus D, Human - pathogenicity | Neurons - pathology | Neurons - virology | Animals | Humans | Brain - pathology | Brain - virology | Encephalitis, Viral - pathology | Enterovirus A, Human - pathogenicity | Enterovirus Infections - pathology | Poliomyelitis - pathology | Coxsackievirus infections | Poliomyelitis
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13. Full Text Cleavage of Interferon Regulatory Factor 7 by Enterovirus 71 3C Suppresses Cellular Responses
by Xiaobo Lei and Xia Xiao and Qinghua Xue and Qi Jin and Bin He and Jianwei Wang
Journal of Virology, ISSN 0022-538X, 02/2013, Volume 87, Issue 3, pp. 1690 - 1698
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
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