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1. Full Text Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation
by Molofsky, Ari B and Van Gool, Frédéric and Liang, Hong-Erh and Van Dyken, Steven J and Nussbaum, Jesse C and Lee, Jinwoo and Bluestone, Jeffrey A and Locksley, Richard M
Immunity (Cambridge, Mass.), ISSN 1074-7613, 07/2015, Volume 43, Issue 1, pp. 161 - 174
Life Sciences & Biomedicine | Immunology | Science & Technology | Obesity - immunology | Intra-Abdominal Fat - cytology | Listeria monocytogenes - immunology | Nippostrongylus - immunology | Lung - cytology | Enzyme Activation - immunology | Inducible T-Cell Co-Stimulator Protein - biosynthesis | T-Lymphocytes, Regulatory - immunology | Aging - immunology | Lymphocyte Activation - immunology | Receptors, Immunologic - biosynthesis | Strongylida Infections - parasitology | Diet, High-Fat | Interleukins - immunology | Strongylida Infections - immunology | Listeriosis - immunology | Inducible T-Cell Co-Stimulator Protein - immunology | Intra-Abdominal Fat - immunology | Lung - pathology | Interleukin-33 | Mice, Transgenic | Animals | Interferon-gamma - immunology | Interleukin-2 - pharmacology | Listeriosis - microbiology | Mice | Interferon-gamma - pharmacology | Lung - immunology | Index Medicus
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2. Full Text IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L
by Kryczek, Ilona and Lin, Yanwei and Nagarsheth, Nisha and Peng, Dongjun and Zhao, Lili and Zhao, Ende and Vatan, Linda and Szeliga, Wojciech and Dou, Yali and Owens, Scott and Zgodzinski, Witold and Majewski, Marek and Wallner, Grzegorz and Fang, Jingyuan and Huang, Emina and Zou, Weiping
Immunity (Cambridge, Mass.), ISSN 1074-7613, 05/2014, Volume 40, Issue 5, pp. 772 - 784
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, CCR6 - immunology | Neoplasm Transplantation | Chemokine CCL20 - metabolism | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Methyltransferases - metabolism | Neoplastic Stem Cells - immunology | Homeodomain Proteins - immunology | Methyltransferases - immunology | Enzyme Activation - immunology | SOXB1 Transcription Factors - metabolism | CD4-Positive T-Lymphocytes - immunology | Chemokine CCL20 - immunology | SOXB1 Transcription Factors - immunology | Interleukins - immunology | Receptors, CCR6 - metabolism | Neoplastic Stem Cells - pathology | Octamer Transcription Factor-3 - immunology | STAT3 Transcription Factor - metabolism | Colorectal Neoplasms - mortality | Nanog Homeobox Protein | HT29 Cells | Animals | Colorectal Neoplasms - immunology | Octamer Transcription Factor-3 - metabolism | Cell Line, Tumor | Mice | STAT3 Transcription Factor - immunology | Colorectal Neoplasms - pathology | Medical research | Colon | Rodents | Colorectal cancer | Stem cells | Index Medicus | Th22 | colon cancer | DOT1L | STAT3 | ILC22 | Cancer stem cell | CCR6 | H3K79 | IL-22 | epigenetics
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3. Full Text Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux
by Karmakar, Mausita and Katsnelson, Michael and Malak, Hesham A and Greene, Neil G and Howell, Scott J and Hise, Amy G and Camilli, Andrew and Kadioglu, Aras and Dubyak, George R and Pearlman, Eric
The Journal of immunology (1950), ISSN 0022-1767, 02/2015, Volume 194, Issue 4, pp. 1763 - 1775
Life Sciences & Biomedicine | Immunology | Science & Technology | Pneumococcal Infections | Potassium - metabolism | Eye Infections, Bacterial - immunology | Keratitis - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - metabolism | Caspase 1 - immunology | Enzyme Activation - immunology | Signal Transduction - immunology | Flow Cytometry | Interleukin-1beta - metabolism | Bacterial Proteins - immunology | Eye Infections, Bacterial - metabolism | Neutrophils - metabolism | Carrier Proteins - immunology | Disease Models, Animal | Apoptosis Regulatory Proteins - immunology | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Neutrophils - immunology | Interleukin-1beta - immunology | Blotting, Western | Mice, Knockout | Spectrophotometry, Atomic | Animals | CARD Signaling Adaptor Proteins | Inflammasomes - immunology | Fluorescent Antibody Technique | Keratitis - metabolism | Mice | Streptolysins - immunology | Index Medicus | Abridged Index Medicus
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4. Full Text Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
by Wen, Haitao and Gris, Denis and Lei, Yu and Jha, Sushmita and Zhang, Lu and Huang, Max Tze-Han and Brickey, Willie June and Ting, Jenny P.-Y
Nature Immunology, ISSN 1529-2908, 05/2011, Volume 12, Issue 5, pp. 408 - 415
Life Sciences & Biomedicine | Immunology | Science & Technology | NLR Family, Pyrin Domain-Containing 3 Protein | Male | Caspase 1 - immunology | Palmitic Acid - immunology | Dietary Fats - immunology | Macrophages | Aminoimidazole Carboxamide - pharmacology | Autophagy - immunology | Ribonucleotides - pharmacology | Flow Cytometry | Reactive Oxygen Species - immunology | Carrier Proteins - immunology | Signal Transduction | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Interleukin-1beta - immunology | Mice, Knockout | Microscopy, Confocal | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Inflammasomes - immunology | Insulin Resistance - immunology | Mice | Enzyme Activation | Oligopeptides - pharmacology | Type 2 diabetes | Care and treatment | Physiological aspects | Cellular signal transduction | Genetic aspects | Inflammation | Research | Fatty acids | Risk factors | Index Medicus
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5. Full Text Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells
by Zevallos, Victor F and Raker, Verena and Tenzer, Stefan and Jimenez-Calvente, Carolina and Ashfaq-Khan, Muhammad and Rüssel, Nina and Pickert, Geethanjali and Schild, Hansjörg and Steinbrink, Kerstin and Schuppan, Detlef
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2017, Volume 152, Issue 5, pp. 1100 - 1113.e12
Gastroenterology and Hepatology | Celiac Disease | Digestion | Gluten | Wheat Sensitivity | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Glutens - immunology | Triticum - immunology | Humans | Colon - immunology | Ileum - immunology | Intestines - immunology | Celiac Disease - immunology | Myeloid Cells - immunology | Colitis - chemically induced | Interferon Inducers - toxicity | Colitis - immunology | Diet, Gluten-Free | Adaptive Immunity | Duodenum - immunology | Cell Line | Trypsin Inhibitors - immunology | Mice, Inbred C57BL | Plant Proteins - immunology | Inflammation | Mesentery | Toll-Like Receptor 4 - immunology | Lymph Nodes - immunology | Poly I-C - toxicity | Dextran Sulfate - toxicity | Immunity, Innate - immunology | Amylases - antagonists & inhibitors | Animals | Mice | Trypsin inhibitors | Medical colleges | Amylases | Trypsin | Immunotherapy | Wheat | Dextran | Enzymes | Dendritic cells | Proteolysis | Gluten-free diet | Hydrolases | Sulfates | Index Medicus | Abridged Index Medicus
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6. Full Text Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b
by Liu, Haibo and Jin, Jing and Cao, Xuetao and Xu, Sheng and Han, Chaofeng and Li, Nan
Nature immunology, ISSN 1529-2908, 08/2010, Volume 11, Issue 8, pp. 734 - 742
Life Sciences & Biomedicine | Immunology | Science & Technology | Proto-Oncogene Proteins c-cbl - metabolism | Protein-Tyrosine Kinases - metabolism | Intracellular Signaling Peptides and Proteins - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Protein-Tyrosine Kinases - immunology | Myeloid Differentiation Factor 88 - immunology | Adaptor Proteins, Signal Transducing - immunology | Syk Kinase | Macrophages - immunology | CD11b Antigen - immunology | Signal Transduction | Toll-Like Receptors - immunology | Escherichia coli - immunology | Inflammation - immunology | Adaptor Proteins, Vesicular Transport - immunology | src-Family Kinases - immunology | Mice, Knockout | Gene Expression Regulation, Enzymologic | Immunity, Innate - immunology | Animals | Escherichia coli Infections - immunology | Mice | Enzyme Activation | Adaptor Proteins, Signal Transducing - metabolism | Inflammation - enzymology | Myeloid Differentiation Factor 88 - metabolism | Proto-Oncogene Proteins c-cbl - immunology | Cell receptors | Immune response | Cell adhesion | Physiological aspects | Research | Health aspects | Integrins | Index Medicus
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7. Full Text PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced: MDSC-mediated T cell activation
by Noman, Muhammad Zaeem and Desantis, Giacomo and Janji, Bassam and Hasmim, Meriem and Karray, Saoussen and Dessen, Philippe and Bronte, Vincenzo and Chouaib, Salem
The Journal of experimental medicine, ISSN 0022-1007, 2014, Volume 211, Issue 5, pp. 781 - 790
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cell Hypoxia - immunology | Enzyme-Linked Immunosorbent Assay | Gene Expression Regulation - immunology | Organic Chemicals | Mice, Inbred C57BL | Tumor Microenvironment - immunology | B7-H1 Antigen - metabolism | Lymphocyte Activation - immunology | Animals | Flow Cytometry | Chromatin Immunoprecipitation | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Luciferases | Myeloid Cells - immunology | Female | T-Lymphocytes - immunology | Mice | Real-Time Polymerase Chain Reaction | Index Medicus | Life Sciences | Cancer | Brief Definitive Report
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8. Full Text Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic amp-protein kinase a and inflammasome-dependent IL-1 signaling
by Larena, Maximilian and Holmgren, Jan and Lebens, Michael and Terrinoni, Manuela and Lundgren, Anna and Sahlgrenska akademin and Institute of Biomedicine, Department of Microbiology and Immunology and Göteborgs universitet and Gothenburg University and Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi and Sahlgrenska Academy
The Journal of immunology (1950), ISSN 0022-1767, 04/2015, Volume 194, Issue 8, pp. 3829 - 3839
Life Sciences & Biomedicine | Immunology | Science & Technology | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | Adjuvants, Immunologic - pharmacology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Middle Aged | Interleukin-1beta - immunology | Male | Caspase 1 - immunology | Enzyme Activation - drug effects | Enzyme Activation - immunology | Signal Transduction - immunology | Signal Transduction - drug effects | Calcium-Binding Proteins - immunology | Cyclic AMP-Dependent Protein Kinases - immunology | Cyclic AMP - immunology | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - immunology | Th17 Cells - immunology | Adult | Female | Th17 Cells - cytology | Cholera Toxin - pharmacology | Carrier Proteins - immunology | Index Medicus | Abridged Index Medicus | Calcium-Binding Proteins/immunology | Signal Transducing/immunology | Apoptosis Regulatory Proteins/immunology | Cyclic AMP/ immunology | Enzyme Activation/drug effects/immunology | Adjuvants | Immunologi inom det medicinska området | Interleukin-1beta/ immunology | Adaptor Proteins | Th17 Cells/cytology/ immunology | Signal Transduction/ drug effects/immunology | Caspase 1/immunology | Carrier Proteins/immunology | Cholera Toxin/ pharmacology | Cyclic AMP-Dependent Protein Kinases/ immunology | CARD Signaling Adaptor Proteins/immunology | Immunologic/ pharmacology | Immunology in the medical area | Inflammasomes/ immunology
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