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The Journal of immunology (1950), ISSN 1550-6606, 2009, Volume 183, Issue 10, pp. 6469 - 6477
Alternatively activated macrophages (AAM) play a crucial role in type 2 immunity. Mice deficient in ST2, a receptor for the latest member of the IL-1 family,... 
IL-1-LIKE CYTOKINE IL-33 | IMMUNE-RESPONSE | ST2 RECEPTOR | EFFECTOR FUNCTION | MAST-CELLS | IN-VIVO | INDUCED ARTHRITIS | ALVEOLAR MACROPHAGES | INTERLEUKIN-1 RECEPTOR | IMMUNOLOGY | T-CELLS | Interleukin-1 Receptor-Like 1 Protein | Asthma - metabolism | Epithelial Cells - metabolism | Ovalbumin - immunology | Humans | Middle Aged | Chemokine CCL24 - metabolism | Interleukin-13 - immunology | Male | Interleukins - metabolism | Receptors, Interleukin - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Interleukins - immunology | Asthma - immunology | Chemokine CCL17 - immunology | Adult | Female | Interleukin-4 - genetics | Macrophages, Alveolar - immunology | Recombinant Proteins - metabolism | Cell Polarity - immunology | Lung - pathology | Receptors, Interleukin - immunology | Interleukin-33 | Macrophage Activation - immunology | Receptors, Interleukin-1 - immunology | Interleukin-4 - metabolism | Receptors, Interleukin-4 - metabolism | Inflammation - immunology | Receptors, Interleukin-4 - immunology | Interleukin-13 - metabolism | Chemokine CCL24 - immunology | Receptors, Interleukin - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Interleukin-4 - immunology | Animals | Eosinophilia - immunology | Recombinant Proteins - immunology | Epithelial Cells - immunology | Receptors, Interleukin-4 - genetics | Mice | Mice, Inbred BALB C | Macrophages, Alveolar - metabolism | Chemokine CCL17 - metabolism | Lung - immunology
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2002, Volume 169, Issue 1, pp. 443 - 453
We have biologically characterized two new members of the IL-17 cytokine family: IL-17F and IL-25. In contrast to conventional in vitro screening approaches,... 
RECEPTOR-GAMMA CHAIN | LYMPHOID DEVELOPMENT | ANTIBODY | ASTHMA | GENE-THERAPY | AIRWAY HYPERRESPONSIVENESS | DEFICIENT MICE | IMMUNOLOGY | IDENTIFICATION | CELL | EXPRESSION | Interleukin-13 - physiology | Bronchial Hyperreactivity - immunology | Humans | Pulmonary Eosinophilia - genetics | Pulmonary Eosinophilia - virology | Interleukin-17 - physiology | Male | Th2 Cells - immunology | Lymphocyte Subsets - immunology | Leukocytosis - virology | Cell Movement - immunology | Th1 Cells - metabolism | RNA, Messenger - biosynthesis | Growth Substances - genetics | Interleukins | Adenoviridae - immunology | Growth Substances - administration & dosage | Amino Acid Sequence | Leukocytosis - immunology | Interleukin-17 - genetics | Neutrophils - virology | Intestinal Diseases, Parasitic - immunology | Mice, Knockout | Mice | Mice, Inbred BALB C | Amino Acid Motifs - genetics | Strongylida Infections - genetics | Molecular Sequence Data | Interleukin-5 - biosynthesis | Th1 Cells - immunology | Hematopoietic Stem Cells - immunology | Interleukin-17 - chemistry | Intestinal Diseases, Parasitic - genetics | Growth Substances - chemistry | Strongylida Infections - immunology | Basophils - immunology | Adenoviridae - genetics | Killer Cells, Natural - immunology | Female | Mucus - metabolism | Interleukin-5 - physiology | Lung - metabolism | Pulmonary Eosinophilia - immunology | Mast Cells - immunology | Lung - pathology | Mice, Inbred C57BL | Aspergillosis - genetics | Neutrophils - immunology | Hematopoietic Stem Cells - metabolism | Inflammation - immunology | Interleukin-17 - biosynthesis | Administration, Intranasal | Th2 Cells - metabolism | Sequence Homology, Amino Acid | Animals | Amino Acid Motifs - immunology | Growth Substances - physiology | Inflammation - genetics | Genetic Vectors | Leukocytosis - genetics | Granulocytes - immunology | Lung - immunology | Aspergillosis - immunology
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2003, Volume 171, Issue 7, pp. 3645 - 3654
textabstractThe prevalence of atopic asthma, a Th2-dependent disease, is reaching epidemic proportions partly due to improved hygiene in industrialized... 
Bone Marrow Cells/immunology/metabolism | Interleukin-12/biosynthesis/genetics/physiology | CD4-Positive T-Lymphocytes/immunology/metabolism | Ovalbumin/administration & dosage/immunology | Adoptive Transfer | Lung/cytology/immunology/metabolism | Pulmonary Eosinophilia/immunology/pathology/prevention & control | Cell Division/immunology | Lipopolysaccharides/administration & dosage/pharmacology | Female | Epitopes, T-Lymphocyte/immunology | Growth Inhibitors/administration & dosage | Cells, Cultured | Protein Subunits/biosynthesis/genetics/physiology | T-Lymphocyte Subsets/cytology/immunology/transplantation | Mice, Transgenic | Immunosuppressive Agents/administration & dosage/pharmacology | Mice, Knockout | Cell Movement/immunology | Animals | Research Support, Non-U.S. Gov't | Cell Differentiation/immunology | Lymphocyte Activation/immunology | Mice | Mice, Inbred BALB C | Dendritic Cells/cytology/immunology/metabolism | Th2 Cells/cytology/immunology/metabolism | CPG OLIGODEOXYNUCLEOTIDES | INHALED ANTIGEN | IFN-GAMMA | IMMUNE-RESPONSES | IN-VIVO | BONE-MARROW | REGULATORY T-CELLS | ASTHMA | CYTOKINE | IMMUNOLOGY | MURINE | T-Lymphocyte Subsets - immunology | Ovalbumin - immunology | T-Lymphocyte Subsets - cytology | Interleukin-12 - genetics | Dendritic Cells - immunology | Lipopolysaccharides - administration & dosage | Interleukin-12 - physiology | Th2 Cells - immunology | Lung - cytology | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Lymphocyte Activation - immunology | Cell Division - immunology | Bone Marrow Cells - immunology | Lung - metabolism | Epitopes, T-Lymphocyte - immunology | Protein Subunits - physiology | Immunosuppressive Agents - pharmacology | Dendritic Cells - metabolism | Immunosuppressive Agents - administration & dosage | Interleukin-12 - biosynthesis | Protein Subunits - genetics | Pulmonary Eosinophilia - immunology | Pulmonary Eosinophilia - prevention & control | CD4-Positive T-Lymphocytes - metabolism | Th2 Cells - cytology | Protein Subunits - biosynthesis | T-Lymphocyte Subsets - transplantation | Pulmonary Eosinophilia - pathology | Th2 Cells - metabolism | Cell Differentiation - immunology | Growth Inhibitors - administration & dosage | Ovalbumin - administration & dosage | Lipopolysaccharides - pharmacology | Dendritic Cells - cytology | Bone Marrow Cells - metabolism | Lung - immunology
Journal Article
Immunobiology, ISSN 0171-2985, 2014, Volume 219, Issue 7, pp. 565 - 571
Abstract Astragaloside IV is the chief ingredient of Radix Astragali, which has been used in the Traditional Chinese Medicine as a major component of many... 
Allergy and Immunology | Advanced Basic Science | Th1/Th2 | Astragaloside IV | Treg | Asthma | EOSINOPHILS | TOLERANCE | AIRWAY INFLAMMATION | IMMUNOLOGY | INTERLEUKIN-5 | IL-10 | IN-VIVO | DISEASE | MICE | EXPRESSION | Bronchial Hyperreactivity - immunology | Triterpenes - immunology | Bronchoalveolar Lavage Fluid - immunology | Drugs, Chinese Herbal - pharmacology | Th2 Cells - immunology | Interferon-gamma - metabolism | Th2 Cells - drug effects | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Forkhead Transcription Factors - metabolism | Asthma - immunology | Interleukin-2 Receptor alpha Subunit - immunology | Anti-Asthmatic Agents - pharmacology | Th1 Cells - drug effects | Anti-Inflammatory Agents - pharmacology | Saponins - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 - immunology | T-Lymphocytes, Regulatory - drug effects | Interleukin-2 Receptor alpha Subunit - metabolism | Lung - drug effects | Inflammation - prevention & control | Mice, Inbred BALB C | Interleukin-10 - immunology | Saponins - pharmacology | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Triterpenes - pharmacology | Asthma - prevention & control | Eosinophilia - chemically induced | Anti-Inflammatory Agents - immunology | Th1 Cells - immunology | Flow Cytometry | Interleukin-10 - metabolism | Female | Lung - metabolism | Anti-Asthmatic Agents - immunology | Cytokines - immunology | Ovalbumin | Cytokines - metabolism | Interleukin-4 - metabolism | Inflammation - immunology | Bronchial Hyperreactivity - prevention & control | Forkhead Transcription Factors - genetics | Th2 Cells - metabolism | Asthma - chemically induced | Animals | Eosinophilia - immunology | Interferon-gamma - immunology | Eosinophilia - prevention & control | Lung - immunology
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2015, Volume 43, Issue 1, pp. 175 - 186
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 04/2016, Volume 99, Issue 4, pp. 619 - 628
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2010, Volume 159, Issue 3, pp. 617 - 625
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2017, Volume 139, Issue 3, pp. 1007 - 1016.e9
Journal Article
Clinical Immunology, ISSN 1521-6616, 2016, Volume 163, pp. 60 - 65
Abstract Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a monogenic autoimmune disease characterized by early-onset... 
Allergy and Immunology | Autoimmunity | IPEX | Mutation | FOXP3 | Primary immunodeficiency | X-LINKED SYNDROME | ENTEROPATHY | STABILITY | IMMUNOLOGY | IMMUNE DYSREGULATION | DIMER | SEQUENCE | DISEASE | REGULATORY T-CELLS | POLYENDOCRINOPATHY | IMMUNODYSREGULATION | Eczema - genetics | Eczema - immunology | Immune System Diseases - genetics | Humans | Diabetes Mellitus, Type 1 - congenital | Infant | Male | Meningoencephalitis - immunology | Thrombocytopenia - genetics | Immunoglobulin E - immunology | Diarrhea - immunology | Eosinophilia - genetics | Fatal Outcome | Hepatomegaly - immunology | Genetic Diseases, X-Linked - genetics | Diabetes Mellitus, Type 1 - immunology | Dimerization | Hemorrhage - genetics | Sepsis - immunology | Splenomegaly - genetics | Growth Disorders - immunology | Hemorrhage - immunology | Splenomegaly - immunology | Thrombocytopenia - immunology | Immune System Diseases - immunology | Leukocytosis - immunology | Meningoencephalitis - genetics | Diabetes Mellitus, Type 1 - genetics | Models, Molecular | Klebsiella Infections - genetics | Hepatomegaly - genetics | Forkhead Transcription Factors - genetics | Sepsis - genetics | Lung Diseases - immunology | Genetic Diseases, X-Linked - immunology | Immune System Diseases - congenital | Thymus Gland - abnormalities | Lung Diseases - genetics | Eosinophilia - immunology | Diarrhea - genetics | Klebsiella Infections - immunology | Phenylalanine - genetics | Hydrophobic and Hydrophilic Interactions | Growth Disorders - genetics | Leukocytosis - genetics
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1594 - 1602
Background Thymic stromal lymphopoietin (TSLP) and IL-33 are considered important initiators of type 2 immunity. In asthmatic patients allergic inflammatory... 
Allergy and Immunology | Hematopoietic progenitor cells | thymic stromal lymphopoietin | asthma | BONE-MARROW | AIRWAY INFLAMMATION | INTERLEUKIN-13 | EOSINOPHIL PROGENITORS | IMMUNOLOGY | RESPONSES | FACTOR-1-ALPHA | ALLERGY | SPUTUM EOSINOPHILIA | DISEASE | EXACERBATIONS | CORTICOSTEROIDS | Interleukin-1 Receptor-Like 1 Protein | Sputum - cytology | Eosinophils - drug effects | Humans | Middle Aged | Hematopoietic Stem Cells - pathology | Interleukin-13 - immunology | Male | Interleukin-7 Receptor alpha Subunit - immunology | Interleukin-5 - genetics | Eosinophils - immunology | Forced Expiratory Volume | Interleukins - genetics | Hematopoietic Stem Cells - immunology | Interleukin-13 - genetics | Interleukin-13 Receptor alpha1 Subunit - immunology | Sputum - immunology | Chemokine CXCL12 - genetics | Interleukins - immunology | Methacholine Chloride - pharmacology | Asthma - immunology | Adult | Eosinophils - pathology | Interleukin-7 Receptor alpha Subunit - genetics | Cytokines - genetics | Receptors, Cytokine - genetics | Chemokine CXCL12 - immunology | Cytokines - immunology | Hematopoietic Stem Cells - drug effects | Interleukin-33 | Gene Expression Regulation | Administration, Inhalation | Immunity, Innate | Receptors, Cell Surface - immunology | Asthma - genetics | Interleukin-13 Receptor alpha1 Subunit - genetics | Interleukin-5 - immunology | Cell Movement - drug effects | Receptors, Cytokine - immunology | Allergens - pharmacology | Primary Cell Culture | Asthma - pathology | Receptors, Cell Surface - genetics | Care and treatment | Asthma | Studies | Flow cytometry | Airway management | Cytokines | Pathogenesis | Migration | Family medical history | Allergies
Journal Article
Journal Article