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PLoS Pathogens, ISSN 1553-7366, 09/2013, Volume 9, Issue 9, pp. e1003615 - e1003615
Respiratory virus infections, such as influenza, typically induce a robust type I (pro-inflammatory cytokine) immune response, however, the production of type... 
LUNG | EOSINOPHILS | MICROBIOLOGY | T(H)2-TYPE RESPONSES | INTERLEUKIN-5 | CD8(+) T-CELLS | ADAPTIVE IMMUNITY | IL-1-LIKE CYTOKINE IL-33 | VIROLOGY | IN-VIVO | TYPE-2 IMMUNITY | RESPIRATORY SYNCYTIAL VIRUS | PARASITOLOGY | Influenza A Virus, H1N1 Subtype - immunology | Up-Regulation | Eosinophils - metabolism | Macrophages, Alveolar - pathology | Killer Cells, Natural - pathology | Eosinophils - immunology | Interleukins - metabolism | Protein Subunits - metabolism | Receptors, Interleukin - metabolism | Lung - virology | Killer Cells, Natural - immunology | Eosinophils - pathology | Lung - metabolism | Respiratory Tract Infections - virology | Macrophages, Alveolar - immunology | Respiratory Tract Infections - pathology | Macrophages, Alveolar - virology | Eosinophilia - etiology | Lung - pathology | Respiratory Tract Infections - metabolism | Specific Pathogen-Free Organisms | Interleukin-33 | Interleukin-5 - metabolism | Killer Cells, Natural - virology | Orthomyxoviridae Infections - metabolism | Eosinophils - virology | Mice, Inbred C57BL | Orthomyxoviridae Infections - pathology | Cells, Cultured | Immunity, Innate | Mice, Knockout | Animals | Respiratory Tract Infections - immunology | Mice, Inbred BALB C | Killer Cells, Natural - metabolism | Macrophages, Alveolar - metabolism | Orthomyxoviridae Infections - virology | Lung - immunology | Orthomyxoviridae Infections - immunology | Killer cells | Interleukins | Influenza | Physiological aspects | Host-parasite relationships | Research | Health aspects | Index Medicus | T cell receptors | Immunology | Lungs | Rodents | Immune system
Journal Article
Journal Article
Vaccine, ISSN 0264-410X, 2016, Volume 35, Issue 5, pp. 757 - 766
Highlights • A single dose of 3 × 105 CFUs of rBCG-N-hRSV cGMP elicits T-cell memory against hRSV. • rBCG-N-hRSV cGMP elicits a strong antiviral TH1/TH17... 
Allergy and Immunology | Human respiratory syncytial virus | Pulmonary inflammation | Bacillus Calmette et Guerin | T cells | Th1 | Viral infection | Th17 | Recombinant vaccine | MEDICINE, RESEARCH & EXPERIMENTAL | RECRUITMENT | DENDRITIC CELLS | ENHANCED DISEASE | INFLUENZA | IMMUNOLOGY | PULMONARY EOSINOPHILIA | RESPONSES | INFANTS | ALVEOLAR MACROPHAGES | EXPRESSION | YOUNG-CHILDREN | Immunogenicity, Vaccine | Respiratory Syncytial Virus Vaccines - immunology | Humans | Nucleoproteins - genetics | Interleukin-17 - immunology | Viral Proteins - immunology | Th1 Cells - immunology | Respiratory Syncytial Virus Infections - immunology | Th17 Cells - virology | Th1 Cells - virology | BCG Vaccine - genetics | Lung - virology | Th17 Cells - drug effects | Immunity, Cellular - drug effects | Respiratory Syncytial Virus Infections - prevention & control | Immunization Schedule | Respiratory Syncytial Virus Infections - virology | Respiratory Syncytial Virus, Human - pathogenicity | Nucleoproteins - immunology | Th1 Cells - drug effects | Respiratory Syncytial Virus, Human - drug effects | Viral Proteins - genetics | Interleukin-17 - biosynthesis | Animals | CD8-Positive T-Lymphocytes - virology | Lymphocyte Activation - drug effects | Respiratory Syncytial Virus, Human - immunology | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Lung - drug effects | Respiratory Syncytial Virus Vaccines - administration & dosage | BCG Vaccine - immunology | Th17 Cells - immunology | Vaccines, Synthetic | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Respiratory Syncytial Virus Vaccines - genetics | BCG Vaccine - administration & dosage | Interferon-gamma - biosynthesis | Lung - immunology | Virus diseases | Prevention | Vaccines | Health aspects | Antigens | Pneumonia | Vaccination | Bacterial pneumonia | Disease susceptibility | Epidemics | Pathogenesis | Neutrophils | Viruses | T cell receptors | Infections | Pathology | Immunology | Respiratory syncytial virus | Lungs | Lymphocytes | Laboratory animals | Public health | Index Medicus | Life Sciences | Human health and pathology
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0181425 - e0181425
Asthma exacerbation can be a life-threatening condition, and is most often triggered by common respiratory viruses. Poor asthma control and worsening of... 
INFECTION DETERMINES | GLUCOCORTICOIDS | BRONCHIAL EPITHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | RHINOVIRUS | EXACERBATIONS | MUSCARINIC RECEPTOR DYSFUNCTION | CD4(+) T-CELLS | SPUTUM EOSINOPHILS | GUINEA-PIG | RESPIRATORY SYNCYTIAL VIRUS | Respirovirus Infections - complications | Guinea Pigs | Humans | Inflammation - virology | Respirovirus Infections - drug therapy | Inflammation - immunology | Immunologic Memory - drug effects | Respiratory Hypersensitivity - immunology | Asthma - drug therapy | Dexamethasone - therapeutic use | Respiratory Hypersensitivity - drug therapy | Animals | Lymphocytes - immunology | Respiratory Hypersensitivity - virology | Lymphocytes - virology | Inflammation - drug therapy | Asthma - immunology | Anti-Inflammatory Agents - therapeutic use | Female | Parainfluenza Virus 1, Human - immunology | Asthma - virology | Respirovirus Infections - immunology | Disease Models, Animal | Virus diseases | Complications and side effects | Medical research | Care and treatment | Immune response | Medicine, Experimental | Development and progression | Research | Asthma | Corticoids | Allergens | Pediatrics | Respiratory function | Memory | Lung | Critical care | Viruses | Infections | Lymph nodes | Respiratory tract | Cell activation | Immunology | Lymphocytes | Bronchoalveolar lavage | Respiratory tract diseases | Physiology | Pretreatment | Alveoli | Parainfluenza | Activation analysis | Antigen presentation | Ovalbumin | Antigens | Immunological memory | Departments | Dexamethasone | Corticosteroids | Leukocytes (eosinophilic) | Hypersensitivity | Bronchus | Inflammation | Exposure | Histology | Eosinophilia | CD4 antigen | Medicine | Injections | Lungs | Guinea pigs | Influenza | Aerosols | In vitro methods and tests | Viral infections | Lymph | Eosinophils | Index Medicus
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2011, Volume 67, Issue 2, pp. 269 - 275
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2003, Volume 170, Issue 9, pp. 4601 - 4611
Most infections with respiratory viruses induce Th1 responses characterized by the generation of Th1 and CD8(+) T cells I secreting IFN-gamma, which in turn... 
ALLERGIC DISORDERS | EOTAXIN EXPRESSION | INHALED ANTIGEN | IMMUNE-RESPONSES | MOUSE MODEL | MICE | IMMUNOLOGY | MYCOBACTERIUM-BOVIS-BCG | INFLAMMATORY RESPONSE | RESPIRATORY SYNCYTIAL VIRUS | LUNG INFLAMMATION | Bronchial Hyperreactivity - immunology | Ovalbumin - immunology | Th2 Cells - virology | Pulmonary Eosinophilia - virology | Th2 Cells - immunology | Cell Migration Inhibition | Cell Movement - immunology | Allergens - administration & dosage | Interleukin-5 - antagonists & inhibitors | Peptide Fragments - immunology | Chemokines, CC - biosynthesis | Influenza A virus - immunology | Interferon-gamma - deficiency | Th2 Cells - pathology | Lung - parasitology | Orthomyxoviridae Infections - pathology | Goblet Cells - virology | Chemokine CCL11 | Lymphopenia - virology | Mice, Transgenic | Mice, Knockout | Metaplasia | Bronchial Hyperreactivity - pathology | Up-Regulation - immunology | Chemokine CCL2 - biosynthesis | Lymphopenia - immunology | Mice | Mice, Inbred BALB C | Orthomyxoviridae Infections - virology | Strongylida Infections - virology | Nippostrongylus - immunology | Goblet Cells - immunology | Strongylida Infections - immunology | Lung - metabolism | Epitopes, T-Lymphocyte - immunology | Interferon-gamma - genetics | Pulmonary Eosinophilia - immunology | Lung - pathology | Pulmonary Eosinophilia - prevention & control | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Cells, Cultured | Pulmonary Eosinophilia - pathology | Bronchial Hyperreactivity - virology | Animals | Chemokine CCL5 - biosynthesis | Ovalbumin - administration & dosage | Down-Regulation - immunology | Lymphocyte Count | Goblet Cells - pathology | Interferon-gamma - biosynthesis | Lung - immunology | Orthomyxoviridae Infections - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Clinical Immunology, ISSN 1521-6616, 2016, Volume 178, pp. 39 - 44
Abstract Background Hyper-IgE syndrome (HIES) due to DOCK8 deficiency is an autosomal recessive (AR) primary combined immunodeficiency which results in... 
Allergy and Immunology | Adrenal Epstein–Barr virus (EBV)-related Leiomyoma | Hyper-IgE syndrome | Novel mutations | DOCK8 deficiency | Progressive multifocal leukoencephalopathy | Slow virus | Leiomyoma | HOMOZYGOUS DELETION | BONE-MARROW-TRANSPLANTATION | IMMUNE-DEFICIENCY | Adrenal Epstein Barr virus (EBV)-related | IMMUNOLOGY | STAT3 MUTATION | LUNG-CANCER | SMOOTH-MUSCLE TUMORS | STEM-CELL TRANSPLANTATION | ADRENAL-GLAND | Job Syndrome - immunology | Recurrence | Job Syndrome - genetics | Job Syndrome - therapy | Humans | Nasopharyngeal Neoplasms - virology | Child, Preschool | Male | Lymphoma, Large B-Cell, Diffuse - etiology | Mutation, Missense | Leiomyoma - etiology | Young Adult | Leiomyoma - virology | Epstein-Barr Virus Infections - etiology | Female | Child | Nasopharyngeal Neoplasms - etiology | Eosinophilia - etiology | Guanine Nucleotide Exchange Factors - genetics | Hematopoietic Stem Cell Transplantation | Cholangitis, Sclerosing - etiology | Esophagitis - etiology | Eczema - etiology | Lymphoma, Large B-Cell, Diffuse - virology | Adrenal Gland Neoplasms - virology | Adrenal Gland Neoplasms - etiology | Magnetic Resonance Imaging | Job Syndrome - complications | Pedigree | Adolescent | Leukoencephalopathy, Progressive Multifocal - etiology | Consanguinity | Leukoencephalopathy, Progressive Multifocal - diagnostic imaging | Leukoencephalopathy, Progressive Multifocal - pathology | Herpes Simplex - etiology | Staphylococcal Infections - etiology | Gene mutations | Health aspects | Genetic aspects | Index Medicus
Journal Article
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 08/2011, Volume 45, Issue 2, pp. 295 - 303
Mouse models of allergic asthma are characterized by airway hyperreactivity (AHR), Th2-driven eosinophilic airway inflammation, high allergen-specific IgE... 
Allergic asthma | Mouse model | Recombinant congenic mice | Quantitative trait locus | Chromosome 17 | STRAINS | LEISHMANIA-MAJOR | mouse model | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODELS | CELL BIOLOGY | CUTANEOUS LEISHMANIASIS | INBRED MICE | QUANTITATIVE TRAIT LOCI | POSITIONAL CANDIDATE | allergic asthma | RESPIRATORY SYSTEM | ALLERGIC-ASTHMA | GENE-EXPRESSION | quantitative trait locus | AIRWAY HYPERRESPONSIVENESS | recombinant congenic mice | chromosome 17 | Bronchoalveolar Lavage Fluid | Bronchial Hyperreactivity - immunology | Oligonucleotide Array Sequence Analysis | Male | Gene Expression Profiling | Bronchial Hyperreactivity - genetics | Eosinophils - immunology | Airway Remodeling - immunology | Leishmaniasis - virology | Asthma - immunology | Eosinophilia - genetics | Female | Asthma - virology | Disease Models, Animal | Biomarkers - metabolism | Leishmaniasis - immunology | Ovalbumin - genetics | Major Histocompatibility Complex - genetics | Eosinophils - virology | Immunoglobulin E - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Inflammation - virology | Chromosome Mapping | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Asthma - genetics | Bronchial Hyperreactivity - virology | Eosinophilia - virology | Phenotype | Animals | Eosinophilia - immunology | Inflammation - genetics | Mice | Mice, Congenic | Mice, Inbred BALB C | Polymorphism, Single Nucleotide | Leishmaniasis - genetics | Leishmania major | Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2002, Volume 168, Issue 6, pp. 2944 - 2951