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JAMA, ISSN 0098-7484, 10/2003, Volume 290, Issue 16, pp. 2149 - 2158
Journal Article
Cancer Science, ISSN 1347-9032, 08/2016, Volume 107, Issue 8, pp. 1134 - 1140
Journal Article
Cancer, ISSN 0008-543X, 12/2013, Volume 119, Issue 24, pp. 4325 - 4332
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 2014, Volume 15, Issue 8, pp. 13768 - 13801
Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of the improvements in the life quality of patients, their... 
Small-molecule inhibitors | Targeted cancer therapy | Receptor tyrosine kinases | Tyrosine kinase inhibitors | targeted cancer therapy | PAN-ERBB INHIBITOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOGENOUS LEUKEMIA | HEPATOCYTE GROWTH-FACTOR | ACUTE MYELOID-LEUKEMIA | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | tyrosine kinase inhibitors | CELL LUNG-CANCER | PHASE-II TRIAL | receptor tyrosine kinases | CHRONIC LYMPHOCYTIC-LEUKEMIA | TUMOR-GROWTH | C-MET INHIBITOR | small-molecule inhibitors | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Humans | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Small Molecule Libraries - therapeutic use | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - chemistry | Receptor Protein-Tyrosine Kinases - metabolism | fms-Like Tyrosine Kinase 3 - metabolism | Neoplasms - drug therapy | Small Molecule Libraries - chemistry | Protein Kinase Inhibitors - chemistry | Receptor, Epidermal Growth Factor - metabolism | Receptors, Vascular Endothelial Growth Factor - metabolism | Protein Kinase Inhibitors - therapeutic use | Receptors, Platelet-Derived Growth Factor - metabolism | Receptors, Fibroblast Growth Factor - metabolism | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Pharmacology | Inhibitor drugs | Kinases | Cancer
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2012, Volume 18, Issue 1, pp. 74 - 82
The involvement of the MET oncogene in de novo and acquired resistance of non-small cell lung cancers (NSCLCs) to tyrosine kinase inhibitors (TKIs) has... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | ACTIVATION | METASTASIS | ADENOCARCINOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | SENSITIVITY | PTEN | MESENCHYMAL TRANSITION | CELL BIOLOGY | GROWTH-FACTOR RECEPTOR | AMPLIFICATION | INHIBITORS | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Cell Proliferation | Apoptosis - drug effects | Humans | Gene Expression Regulation, Neoplastic | Epithelial-Mesenchymal Transition - drug effects | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Cell Transformation, Neoplastic - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Proto-Oncogene Proteins c-met - genetics | Drug Resistance, Neoplasm - genetics | Animals | Mice, Nude | Quinazolines - therapeutic use | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | MicroRNAs - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Epidermal growth factor | MicroRNA | Physiological aspects | Genetic aspects | Research | Gefitinib | Gene expression | Lung cancer, Non-small cell | Protein kinase C | Mesenchyme | Lung cancer | Homology | Kinases | c-Met protein | Receptors | miRNA | Protein-tyrosine kinase receptors | Tumorigenesis | Growth factors | Protein-tyrosine kinase | Tyrosine | Peptidase | Sarcoma | Epidermal growth factor receptors | Non-small cell lung carcinoma | Ribonucleic acid--RNA |