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The Journal of immunology (1950), ISSN 0022-1767, 10/2017, Volume 199, Issue 7, pp. 2503 - 2514
Heterodimeric IL-27 (p28/EBV-induced gene 3) is an important member of the IL-6/IL-12 cytokine family. IL-27 is predominantly synthesized by mononuclear... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Norepinephrine - pharmacology | Albuterol - pharmacology | Sympathetic Nervous System - immunology | Zymosan - pharmacology | Interleukins - metabolism | Interleukins - genetics | Sympathetic Nervous System - physiology | Receptors, Adrenergic - drug effects | Interleukins - immunology | Macrophages - immunology | Thiadiazoles - pharmacology | Interleukins - blood | Formoterol Fumarate - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Inflammation | Sulfonamides - pharmacology | Toll-Like Receptor 3 - metabolism | Anthracenes - pharmacology | Animals | Shock, Septic | Signal Transduction - drug effects | Poly I-C - metabolism | Lipopolysaccharides - pharmacology | Interleukin-10 - biosynthesis | Macrophages - drug effects | Mice | Macrophage Activation - drug effects | Interleukin-10 - immunology | Epinephrine - pharmacology | Shock | Adrenal glands | Nervous system | Leukocytes (mononuclear) | Feedback loops | Macrophages | Neuromodulation | Interleukin 27 | Neoplasms | Neuroendocrine system | Interleukin 6 | Cell activation | Autonomic nervous system | Modulation | Formoterol | Autocrine signalling | Noradrenaline | Endotoxemia | Epinephrine | CD11b antigen | Immune response | Immunoregulation | Interleukin 12 | Catecholamines | JNK protein | Pharmacology | Sympathetic nervous system | Catecholamine | Gene silencing | Interleukin 10 | Adrenergic receptors | Receptors (physiology) | Hypothermia | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2008, Volume 283, Issue 27, pp. 18493 - 18504
Human platelets express protease-activated receptor 1 (PAR1) and PAR4 but limited data indicate for differences in signal transduction. We studied the... 
Receptor, PAR-1 - metabolism | Humans | Thrombin - antagonists & inhibitors | Receptors, Adrenergic, alpha-2 - metabolism | Secretory Vesicles - metabolism | Hemostatics - pharmacology | Peptide Fragments - pharmacology | Epinephrine - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Epinephrine - agonists | Dose-Response Relationship, Drug | Adrenergic alpha-2 Receptor Agonists | Receptors, Thrombin - agonists | Thrombin - pharmacology | Blood Platelets - cytology | Adenosine Triphosphate - metabolism | Thrombin - agonists | Platelet Aggregation Inhibitors - pharmacology | Platelet Aggregation - drug effects | Aspirin - pharmacology | Aspirin - agonists | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Aspirin - antagonists & inhibitors | Oligopeptides - antagonists & inhibitors | Calcium - pharmacology | Receptor, PAR-1 - agonists | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Platelet Aggregation - physiology | Purinergic P2 Receptor Agonists | Oligopeptides - agonists | Receptors, Purinergic - metabolism | Receptors, Purinergic P2X | Drug Synergism | Drug Antagonism | Purinergic Agonists | Blood Platelets - metabolism | Peptide Fragments - agonists | Peptide Fragments - antagonists & inhibitors | Receptors, Purinergic P2 - metabolism | Receptors, Thrombin - metabolism | Adrenergic alpha-Agonists - pharmacology | Adenosine Diphosphate - metabolism | Adrenergic alpha-2 Receptor Antagonists | Oligopeptides - pharmacology | Epinephrine - pharmacology | Index Medicus
Journal Article
Scientific reports, ISSN 2045-2322, 07/2017, Volume 7, Issue 1, pp. 4810 - 11
Journal Article
British journal of pharmacology, ISSN 0007-1188, 06/2013, Volume 169, Issue 3, pp. 528 - 538
Background and Purpose PDE3 and/or PDE4 control ventricular effects of catecholamines in several species but their relative effects in failing human ventricle... 
inotropism and lusitropism | human heart failure | phosphodiesterases 3 and 4 | noradrenaline and adrenaline | metoprolol | β1 and β2 adrenoceptors | and β | adrenoceptors | Adrenergic beta-1 Receptor Antagonists - adverse effects | Heart Failure - surgery | Cyclic Nucleotide Phosphodiesterases, Type 3 - chemistry | Norepinephrine - pharmacology | Adrenergic alpha-Agonists - chemistry | Phosphodiesterase 3 Inhibitors - pharmacology | Humans | Middle Aged | Adrenergic beta-1 Receptor Antagonists - pharmacology | Heart Failure - physiopathology | Myocardial Contraction - drug effects | Receptors, Adrenergic, beta-1 - chemistry | Adrenergic beta-1 Receptor Antagonists - therapeutic use | Adrenergic beta-Agonists - chemistry | Epinephrine - agonists | Receptors, Adrenergic, beta-2 - chemistry | Cardiotonic Agents - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 4 - chemistry | Adrenergic beta-2 Receptor Antagonists - pharmacology | Adrenergic beta-Agonists - pharmacology | Heart Transplantation | Metoprolol - therapeutic use | Receptors, Adrenergic, beta-1 - metabolism | Drug Resistance - drug effects | Heart Failure - metabolism | Anti-Arrhythmia Agents - therapeutic use | Cardiotonic Agents - pharmacology | Metoprolol - adverse effects | Norepinephrine - agonists | Phosphodiesterase 4 Inhibitors - pharmacology | Receptors, Adrenergic, beta-2 - metabolism | Heart Failure - drug therapy | Heart Ventricles - physiopathology | Anti-Arrhythmia Agents - adverse effects | Adrenergic alpha-Agonists - pharmacology | Heart Ventricles - metabolism | In Vitro Techniques | Epinephrine - pharmacology | Heart Ventricles - drug effects | Index Medicus | Research Paper with
Journal Article
European journal of clinical pharmacology, ISSN 1432-1041, 02/2011, Volume 67, Issue 8, pp. 825 - 831
The aim of this proof-of-concept study was to characterize the pharmacokinetics and pharmacodynamics of intranasal dexmedetomidine compared with its... 
Administration | Biomedicine | Intranasal | Pharmacology/Toxicology | Dexmedetomidine | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Conscious Sedation - methods | Consciousness - drug effects | Injections, Intravenous | Adrenergic alpha-2 Receptor Agonists - pharmacokinetics | Humans | Hypnotics and Sedatives - administration & dosage | Half-Life | Biological Availability | Male | Metabolic Clearance Rate | Adrenergic alpha-2 Receptor Agonists - pharmacology | Heart Rate - drug effects | Adrenergic alpha-2 Receptor Agonists - administration & dosage | Adult | Blood Pressure - drug effects | Dexmedetomidine - pharmacology | Nasal Mucosa - drug effects | Dexmedetomidine - administration & dosage | Hypnotics and Sedatives - pharmacokinetics | Dexmedetomidine - pharmacokinetics | Sleep Stages - drug effects | Administration, Intranasal | Cross-Over Studies | Norepinephrine - blood | Adrenergic alpha-2 Receptor Agonists - blood | Epinephrine - blood | Dexmedetomidine - blood | Hypnotics and Sedatives - blood | Hypnotics and Sedatives - pharmacology | Care and treatment | Pain | Heart beat | Analgesics | Emergency medicine | Noradrenaline | Central nervous system agents | Prescription drugs | Drug delivery systems | Pharmacology | Bioavailability | Index Medicus | Life Sciences | Pharmaceutical sciences
Journal Article
PloS one, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, pp. e0150469 - e0150469
The air-breathing singhi catfish (Heteropneustes fossilis) is frequently being challenged by bacterial contaminants, and different environmental insults like... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Norepinephrine - pharmacology | Nitric Oxide Synthase Type II - biosynthesis | Sodium Chloride - pharmacology | Transcriptional Activation - drug effects | Protein Transport - drug effects | RNA, Messenger - metabolism | Mannitol - pharmacology | Drug Interactions | Liver - drug effects | Catfishes - genetics | Catfishes - physiology | Glutamine - pharmacology | Hormones - pharmacology | Nitric Oxide - biosynthesis | Cell Size - drug effects | Liver - metabolism | RNA, Messenger - genetics | Catfishes - metabolism | Adenosine - pharmacology | Air | Animals | Glycine - pharmacology | Nitric Oxide Synthase Type II - genetics | Perfusion | Lipopolysaccharides - pharmacology | Liver - cytology | Osmotic Pressure - drug effects | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Respiration | Epinephrine - pharmacology | Nitric Oxide Synthase Type II - metabolism | Physiological aspects | Oxidative stress | Research | Mitogens | Health aspects | Nitric oxide | Adaptations | Hydrogen peroxide | Butyl hydroperoxide | Laboratories | Hydrogen | Liver | Zoology | Genes | Homeostasis | Smooth muscle | Biosynthesis | Hormones | Dehydration | Glycine | Tissues | Lipopolysaccharides | Atrophy | Infusion | Metabolites | Catfish | Rodents | Bacteria | Fish | Physiology | Epinephrine | Efflux | Adenosine | Bacterial infections | Hydration | Shrinkage | Injection | Metabolism | Mammals | Gene expression | Nitric-oxide synthase | Ammonia | Hypotonicity | Hypertonicity | Contaminants | Regulation | Norepinephrine | Cell size | Breathing | Peritoneum | Glutamine | Index Medicus
Journal Article