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Cell Stem Cell, ISSN 1934-5909, 09/2012, Volume 11, Issue 3, pp. 401 - 414
The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and... 
MAMMALIAN TARGET | CANCER PATIENTS | RAPAMYCIN | HEAD | AGING PHENOTYPES | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RESPONSE | TUMOR | NECK | SKIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Death - radiation effects | TOR Serine-Threonine Kinases - metabolism | Keratinocytes - radiation effects | Carcinoma, Squamous Cell - pathology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Cell Compartmentation - radiation effects | Mucositis - prevention & control | Mouth Mucosa - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Mouth Mucosa - radiation effects | Mucositis - pathology | Stem Cells - enzymology | Mucositis - enzymology | Cellular Senescence - radiation effects | Cytoprotection - drug effects | Clone Cells | Oxidative Stress - radiation effects | Cell Death - drug effects | Head and Neck Neoplasms - enzymology | Mouth Mucosa - pathology | Keratinocytes - enzymology | Superoxide Dismutase - metabolism | Radiation, Ionizing | Carcinoma, Squamous Cell - enzymology | Epithelial Cells - radiation effects | Cells, Cultured | Stem Cells - radiation effects | Epithelial Cells - pathology | Radiation Injuries - enzymology | Sirolimus - pharmacology | Head and Neck Neoplasms - pathology | Keratinocytes - pathology | Animals | Keratinocytes - drug effects | Radiation Injuries - prevention & control | Epithelial Cells - enzymology | Cell Compartmentation - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Radiation Injuries - pathology | Cell Proliferation - drug effects | Mice | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Cell Proliferation - radiation effects | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7571, pp. 131 - 135
Despite major advances in understanding the molecular and genetic basis of cancer, metastasis remains the cause of >90% of cancer-related mortality(1).... 
INHIBITION | COMMITMENT | MULTIDISCIPLINARY SCIENCES | GROWTH | GENES | MARKERS | IDENTIFICATION | FATE | TUMORS | TRANSCRIPTOME ANALYSIS | MAMMARY-GLAND | Neoplastic Stem Cells - drug effects | Epithelial Cells - drug effects | Humans | Gene Expression Profiling | Epithelial-Mesenchymal Transition - genetics | Cell Differentiation - genetics | Flow Cytometry | Neoplasm Metastasis - drug therapy | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Cyclin-Dependent Kinases - antagonists & inhibitors | Single-Cell Analysis | Disease Models, Animal | Cell Separation | Epithelial Cells - pathology | Mice, SCID | Breast Neoplasms - drug therapy | Disease Progression | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Differentiation - drug effects | Neoplasm Metastasis - pathology | Genes, myc - genetics | Cell Line, Tumor | Mice, Inbred NOD | Cell Proliferation - drug effects | Mesoderm - metabolism | Mice | Cell Transformation, Neoplastic - drug effects | Cell Cycle - drug effects | Cell Transformation, Neoplastic - pathology | Mesoderm - pathology | Stem cells | Cancer cells | Development and progression | Breast cancer | Metastasis | Observations | Health aspects | Bone marrow | Principal components analysis | Gene expression | Tumors | Apoptosis | Index Medicus
Journal Article
Stem Cells, ISSN 1066-5099, 03/2010, Volume 28, Issue 3, pp. 564 - 572
Human mesenchymal stem cells (hMSCs) are multipotent cells that can differentiate into many cell types. Chondrogenesis is induced in hMSCs cultured as a... 
Cell shape | Rac1 | Chondrogenesis | Smooth muscle cells | N-cadherin | Mesenchymal stem cells | MYOBLAST FUSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ADHESION | ONCOLOGY | MESENCHYMAL PROGENITOR CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE-EXPRESSION | CYTOSKELETAL TENSION | DIFFERENTIATION | RHO-GTPASES | PROTEINS | HEMATOLOGY | MODULATION | MAMMARY EPITHELIAL-CELLS | Chondrocytes - cytology | Chondrogenesis - drug effects | Cadherins - metabolism | Humans | Extracellular Matrix - metabolism | Antigens, CD - genetics | Cell Lineage - drug effects | Transforming Growth Factor beta3 - metabolism | Antigens, CD - metabolism | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Cadherins - genetics | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Chondrocytes - metabolism | Transforming Growth Factor beta3 - pharmacology | Mesenchymal Stromal Cells - drug effects | Cell Adhesion - genetics | Muscle Development - physiology | Cells, Cultured | Gene Expression Regulation - physiology | Mesenchymal Stromal Cells - metabolism | Up-Regulation - genetics | Antigens, CD - drug effects | Cadherins - drug effects | Cell Adhesion - drug effects | Cell Lineage - physiology | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Muscle Development - drug effects | rac1 GTP-Binding Protein - drug effects | Cell Differentiation - drug effects | Cell Shape - physiology | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 11/2016, Volume 39, Issue 3, pp. 302 - 315
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, pp. e18271 - e18271
Activation of the RhoA/ROCK signaling pathway has been shown to contribute to dissociation-induced apoptosis of embryonic and neural stem cells. We previously... 
SURVIVAL | STEM-CELLS | SUBPOPULATION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | PTEN | ISOFORM | RHOA | DELETION | KINASES | ACTS | Apoptosis - drug effects | Epithelial Cells - drug effects | Male | Stem Cells - cytology | Spheroids, Cellular - cytology | rho-Associated Kinases - antagonists & inhibitors | Stem Cells - enzymology | rho-Associated Kinases - metabolism | Biological Assay | Clone Cells | Colony-Forming Units Assay | Spheroids, Cellular - drug effects | Epithelial Cells - cytology | Proto-Oncogene Proteins c-akt - metabolism | Amides - pharmacology | Biomarkers - metabolism | PTEN Phosphohydrolase - metabolism | Down-Regulation - drug effects | Animals | Epithelial Cells - enzymology | Prostate - cytology | Stem Cells - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Cloning | Stem cells | Apoptosis | Phosphorylation | Epithelial cells | Embryo cells | Stem cell transplantation | AKT protein | Biology | Activation | Metastasis | Kinases | Assaying | Phosphatase | Proteins | Signal transduction | Cell activation | Efficiency | Transgenic animals | Rodents | Extracellular matrix | Tumorigenesis | Cues | Phenotypes | Immunoglobulins | Colonies | RhoA protein | Progenitor cells | Rho-associated kinase | Medicine | Regeneration | Signaling | Inhibitors | Nitric oxide | Cells (biology) | Neural stem cells | Regulation | Laboratory animals | Prostate cancer | Prostate | PTEN protein | Index Medicus
Journal Article
Journal Article
Cell Stem Cell, ISSN 1934-5909, 01/2017, Volume 20, Issue 1, pp. 41 - 55
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 01/2014, Volume 40, Issue 1, pp. 128 - 139
Commensal gut microflora and dietary fiber protect against colonic inflammation and colon cancer through unknown targets. Butyrate, a bacterial product from... 
INTESTINAL INFLAMMATION | NICOTINIC-ACID | DENDRITIC CELLS | CHAIN FATTY-ACIDS | INTERLEUKIN-10 RECEPTOR | RETINOIC-ACID | REGULATORY T-CELLS | APC(MIN/+) MICE | GUT MICROBIOTA | IMMUNOLOGY | BOWEL-DISEASE | T-Lymphocyte Subsets - immunology | Receptors, G-Protein-Coupled - metabolism | Colonic Neoplasms - prevention & control | Dendritic Cells - immunology | Epithelial Cells - drug effects | Colitis - complications | Colon - immunology | Receptors, G-Protein-Coupled - immunology | T-Lymphocytes, Regulatory - immunology | Niacin - administration & dosage | Microbiota | Butyrates - immunology | Interleukin-10 - metabolism | Colitis - drug therapy | Colitis - immunology | Colonic Neoplasms - etiology | Macrophages - immunology | Receptors, Nicotinic - metabolism | Disease Susceptibility | Colon - pathology | Carcinogenesis - immunology | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Receptors, Nicotinic - immunology | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Epithelial Cells - immunology | Colon - microbiology | Mice | Receptors, G-Protein-Coupled - genetics | Interleukin-18 - genetics | Receptors, Nicotinic - genetics | Interleukin-18 - metabolism | Colon cancer | Metabolites | Dendritic cells | Esters | Inflammation | T cells | Niacin | Inflammatory bowel disease | Colon | Lymphocytes | Rodents | Vitamin B | Colorectal cancer | Index Medicus
Journal Article