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Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4095 - 4106
Journal Article
OncoImmunology, ISSN 2162-4011, 06/2017, Volume 6, Issue 6, p. e1323617
The tumor microenvironment has been identified as a major mediator of immunological processes in solid tumors. In particular, tumor-associated fibroblasts are... 
microenvironment | subpopulation | immune cells | cancer | cytokines | biomarker | co-culture | infiltration | CANCER-ASSOCIATED FIBROBLASTS | TISSUE | IMMUNOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | LUNG-CANCER | MEMORY | ONCOLOGY | IMMUNOTHERAPY | COLORECTAL-CANCER | PROGRESSION
Journal Article
Cancer, ISSN 0008-543X, 08/2017, Volume 123, Issue 16, pp. 3080 - 3087
BACKGROUND Mirvetuximab soravtansine (IMGN853) is an antibody‐drug conjugate that selectively targets folate receptor α (FRα). In this phase 1 dose‐escalation... 
clinical trial | targeted therapy | folate receptor | phase 1 | antibody‐drug conjugate | antibody-drug conjugate | THERAPEUTICS | FARLETUZUMAB | PLATINUM-RESISTANT OVARIAN | MONOCLONAL-ANTIBODY | COMBINATION | EPITHELIAL OVARIAN-CANCER | CHEMOTHERAPY | DELIVERY | THERAPY | ONCOLOGY | PROTEINS | Lung Neoplasms - drug therapy | Humans | Middle Aged | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Fatigue - chemically induced | Diarrhea - chemically induced | Dose-Response Relationship, Drug | Vision Disorders - chemically induced | Aged, 80 and over | Immunoconjugates - therapeutic use | Adult | Female | Hypophosphatemia - chemically induced | Carcinoma, Renal Cell - drug therapy | Ovarian Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - pathology | Neoplasms, Glandular and Epithelial - pathology | Antibodies, Monoclonal, Humanized - therapeutic use | Carcinoma, Renal Cell - pathology | Maytansine - analogs & derivatives | Keratitis - chemically induced | Maytansine - therapeutic use | Disease Progression | Neoplasms - drug therapy | Maximum Tolerated Dose | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Kidney Neoplasms - pathology | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Kidney Neoplasms - drug therapy | Neoplasms - pathology | Cancer patients | Care and treatment | Pharmacokinetics | Health aspects | Analysis | Ovarian cancer | Index Medicus | Abridged Index Medicus
Journal Article
NATURE REVIEWS CANCER, ISSN 1474-175X, 09/2014, Volume 14, Issue 9, pp. 623 - 631
During the past ten years, circulating tumour cells (CTCs) have received enormous attention as new biomarkers and the subject of basic research. Although CTCs... 
EPITHELIAL-MESENCHYMAL TRANSITION | LUNG-CANCER | POLYMERASE-CHAIN-REACTION | ONCOLOGY | COLORECTAL-CANCER | METASTATIC BREAST-CANCER | BONE-MARROW | PERIPHERAL-BLOOD | RESISTANT PROSTATE-CANCER | BIOLOGICAL INSIGHTS | CLINICAL-SIGNIFICANCE
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2016, Volume 139, Issue 2, pp. 433 - 445
The objective of this study was to examine the implication of Y‐box‐binding protein‐1 (YB‐1) for the aggressive phenotypes, prognosis and therapeutic target in... 
SKP2/p27 | MT2‐MMP | antisense oligonucleotide therapy | YB‐1 | pancreatic ductal adenocarcinoma | MT2-MMP | YB-1 | HUMAN BREAST CANCERS | OVARIAN-CANCER | DRUG-RESISTANCE | TRANSLATIONAL ACTIVATION | EPITHELIAL-MESENCHYMAL TRANSITION | GELATINASE-A | ONCOLOGY | TRANSCRIPTION FACTOR YB-1 | PROSTATE-CANCER | IN-VIVO | YE-1 | ANTISENSE OLIGONUCLEOTIDES | Cell Cycle - genetics | Prognosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Male | Carcinoma, Pancreatic Ductal - genetics | Gene Knockdown Techniques | Neoplasm Metastasis | Neoplasm Grading | Aged, 80 and over | Carcinoma, Pancreatic Ductal - mortality | Female | Pancreatic Neoplasms - mortality | Y-Box-Binding Protein 1 - genetics | Disease Models, Animal | Carcinoma in Situ - pathology | Pancreatic Neoplasms - pathology | Kaplan-Meier Estimate | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Animals | Cell Line, Tumor | Aged | Mice | Neoplasm Staging | Proteins | Immunohistochemistry | Cancer patients | Care and treatment | Growth | Analysis | Pancreatic cancer | Metastasis | Protein binding | Cancer | Protein expression | Kinases | Medical prognosis | Cell cycle | Adenocarcinoma | Cell proliferation | Therapy | Surgical implants | Animal models | Correlation | Matrix metalloproteinases | Liver | Oligonucleotides | In vitro testing | Assaying | Tissues | Accumulation | Western blotting | Metastases | Rodents | Inhibition | Pancreas | Monitoring | Binding | Aggressive behavior | Invasiveness | RNA-mediated interference | Implantation | Antisense oligonucleotides | siRNA | Patients | Nuclear factor I | Polymerase chain reaction | Pancreas transplantation | In vivo methods and tests | Tumors | Index Medicus
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1804, pp. 143 - 171
Tumor-associated gangliosides play important roles in regulation of signal transduction induced by growth-factor receptors including EGFR, FGFR, HGF and PDGFR... 
Scavenger pathway | Glycolipid enriched microdomain (GEM) | Epithelial–mesenchymal transition (EMT) | Hematogenous metastasis | De novo synthesis | DNA hypermethylation | Embryonic stem cells | Epigenetic silencing | MicroRNA | Incomplete synthesis | Histone modification | Glycosynapse | Cancer stem cells | Hypoxia inducible factor (HIF)
Journal Article
Oncogenesis, ISSN 2157-9024, 01/2018, Volume 7, Issue 1, pp. 10 - 13
Journal Article