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The Journal of immunology (1950), ISSN 1550-6606, 2005, Volume 174, Issue 12, pp. 7853 - 7858
textabstractT cells require both primary and costimulatory signals for optimal activation. The primary Ag-specific signal is delivered by engagement of the... 
Cytotoxicity, Immunologic/genetics | Adjuvants, Immunologic/genetics/metabolism/toxicity | Antigens, CD28/genetics/immunology/physiology | Comparative Study | Receptors, IgE/genetics/metabolism/physiology | Humans | Binding Sites, Antibody/genetics | HLA-A1 Antigen/genetics/immunology/metabolism | Immunoglobulin Variable Region/genetics/metabolism | T-Lymphocytes, Cytotoxic/immunology/metabolism | Transduction, Genetic/methods | Neoplasm Proteins/genetics/immunology/metabolism | Lymphocyte Activation/genetics | Immunoglobulin Fab Fragments/genetics/metabolism/toxicity | Research Support, Non-U.S. Gov't | Protein Structure, Tertiary/genetics | K562 Cells | Signal Transduction/genetics/immunology | Cell Line, Tumor | Receptors, Antigen, T-Cell/biosynthesis/genetics/metabolism | Epitopes, T-Lymphocyte/genetics/immunology/toxicity | Cytokines/biosynthesis | Melanoma/immunology/pathology | TUMOR-INFILTRATING LYMPHOCYTES | SIGNAL-TRANSDUCTION | METASTATIC MELANOMA | ACTIVATION | TCR | CANCER REGRESSION | CO-STIMULATION | PROLIFERATION | IMMUNOLOGY | CHIMERIC SINGLE-CHAIN | RECEPTOR GENES | HLA-A1 Antigen - genetics | Neoplasm Proteins - immunology | Immunoglobulin Variable Region - metabolism | Epitopes, T-Lymphocyte - genetics | Immunoglobulin Fab Fragments - toxicity | Neoplasm Proteins - metabolism | Receptors, Antigen, T-Cell - biosynthesis | Signal Transduction - immunology | Lymphocyte Activation - genetics | CD28 Antigens - genetics | Immunoglobulin Fab Fragments - metabolism | Adjuvants, Immunologic - metabolism | Adjuvants, Immunologic - genetics | Epitopes, T-Lymphocyte - immunology | Neoplasm Proteins - genetics | Transduction, Genetic - methods | HLA-A1 Antigen - metabolism | CD28 Antigens - physiology | T-Lymphocytes, Cytotoxic - immunology | Cytotoxicity, Immunologic - genetics | Melanoma-Specific Antigens | Receptors, IgE - physiology | Antigens, Neoplasm | Binding Sites, Antibody - genetics | Immunoglobulin Fab Fragments - genetics | Receptors, Antigen, T-Cell - metabolism | Adjuvants, Immunologic - toxicity | CD28 Antigens - immunology | Protein Structure, Tertiary - genetics | Signal Transduction - genetics | Melanoma - pathology | Receptors, IgE - genetics | Receptors, IgE - metabolism | T-Lymphocytes, Cytotoxic - metabolism | Melanoma - immunology | Epitopes, T-Lymphocyte - toxicity | Immunoglobulin Variable Region - genetics | HLA-A1 Antigen - immunology | Receptors, Antigen, T-Cell - genetics | Cytokines - biosynthesis
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 340, Issue 6128, pp. 87 - 91
Journal Article
PLoS genetics, ISSN 1553-7404, 2016, Volume 12, Issue 8, p. e1006226
Journal Article
Journal Article
Journal Article
PLoS biology, ISSN 1545-7885, 2019, Volume 17, Issue 1, p. e3000131
...-evolutionary arms race with pathogens is considered largely responsible for the observed exceptionally high levels of genetic diversity [3-6], yet it cannot fully account... 
HLA-DR | BIOCHEMISTRY & MOLECULAR BIOLOGY | NATURAL-SELECTION | DISEASE | BIOLOGY | RISK | LOCI | PEPTIDE-BINDING REGION | EXPRESSION | ANTIGEN | Major Histocompatibility Complex - physiology | Blood-Borne Pathogens | Major Histocompatibility Complex - genetics | Humans | Peptides - genetics | Antigen Presentation - genetics | Amino Acid Sequence - genetics | Antigen Presentation - immunology | Epitopes - genetics | Adaptive Immunity - genetics | Selection, Genetic - genetics | Biological Evolution | Animals | Histocompatibility Antigens Class II - immunology | Genetic Variation - genetics | Histocompatibility Antigens Class II - genetics | Epitopes - physiology | Evolution, Molecular | Physiological aspects | Genetic aspects | Major histocompatibility complex | Pathogenic microorganisms | Natural history | Adaptive systems | Populations | Peptides | Mental disorders | Funding | Positive selection | Genomes | Biology | Biochemistry | Epidemiology | Population genetics | Human populations | Proteins | Human immunodeficiency virus--HIV | Drb1 protein | Phylogenetics | Evolution | Genetics | Bioinformatics | Supervision | Immune system | Geographical distribution | Antigen presentation | Antigens | Pathogens | Immune response | Dermatology | Dengue fever | Genetic diversity | Epitopes | Immunological tolerance | Biological research | Vertebrates | Infectious diseases | Alleles | Software | Autoimmune diseases | HIV | Human immunodeficiency virus
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 1121 - 8
Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria... 
SYSTEM | ENTRY | MECHANISM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | DOXORUBICIN | TUMOR | VALIDATION | MICROSCOPY | BINDING | DELIVERY | Receptors, Virus - metabolism | Humans | Arenaviruses, New World - genetics | Arenaviruses, New World - metabolism | Plasmodium vivax - genetics | Substrate Specificity | Hemochromatosis Protein - chemistry | Receptors, Virus - genetics | Protozoan Proteins - genetics | Antigens, CD - genetics | Transferrin - genetics | Apoferritins - metabolism | Antigens, CD - metabolism | Protozoan Proteins - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Viral Envelope Proteins - metabolism | Protozoan Proteins - chemistry | Antigens, CD - chemistry | Protein Interaction Domains and Motifs | Receptors, Transferrin - genetics | Binding Sites | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Plasmodium vivax - metabolism | Viral Envelope Proteins - genetics | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Recombinant Proteins - chemistry | Apoferritins - chemistry | Apoferritins - genetics | Hemochromatosis Protein - metabolism | Recombinant Proteins - genetics | Receptors, Transferrin - metabolism | Cryoelectron Microscopy | Receptors, Virus - chemistry | Protein Conformation, beta-Strand | Escherichia coli - genetics | Hemochromatosis Protein - genetics | Viral Envelope Proteins - chemistry | Transferrin - chemistry | Protein Binding | HeLa Cells | Transferrin - metabolism | Receptors, Transferrin - chemistry | Binding | Vector-borne diseases | Pathogens | Transferrin | Endocytosis | Malaria | Ferritin | Iron | Epitopes | Electron microscopy | Cellular structure | Mimicry
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 12/2011, Volume 6, Issue 12, p. e27947
.... Here we apply molecular population genetics and molecular evolution analyses using Daphnia magna and several Drosophila species to investigate the potential role of natural... 
MAXIMUM-LIKELIHOOD | CODON-SUBSTITUTION MODELS | SPECIFICITY | NUCLEOTIDE SUBSTITUTION | MOLECULAR EVOLUTION | OVERDOMINANT SELECTION | DETECTING POSITIVE SELECTION | BALANCING SELECTION | POLYMORPHISM | LOCUS | TESTS | OVERDOMINANT | MULTIDISCIPLINARY SCIENCES | SOFTWARE | Geography | Gene Conversion - genetics | Gene Dosage - genetics | Genetics, Population | Cell Adhesion Molecules - genetics | Genes, Insect - genetics | Alternative Splicing - genetics | Selection, Genetic | Models, Molecular | Nucleotides - genetics | Exons - genetics | Drosophila melanogaster - genetics | Polymorphism, Genetic | Likelihood Functions | Animals | Drosophila melanogaster - chemistry | Gene Duplication - genetics | Epitopes - chemistry | Drosophila Proteins - genetics | Daphnia - genetics | Analysis | Genes | Drosophila | Genetic engineering | Genetic aspects | Down syndrome | Population genetics | Antigenic determinants | Protein binding | Alternative splicing | Divergence | Exons | Biological evolution | Positive selection | Nervous system | Genomes | Cell adhesion molecules | Proteins | Crustaceans | Adhesive strength | Down's syndrome | Reproduction (copying) | DSCAM protein | Cell adhesion | Genetics | Trends | Species | Immune system | Binding | Pathogens | Immunoglobulins | Neural cell adhesion molecule | Splicing | Epitopes | Natural selection | Molecular evolution | Insects | Isoforms | Alleles | Molecular biology | Females | Arrays | Gene conversion | Evolution & development | Structural analysis
Journal Article