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The Journal of biological chemistry, ISSN 1083-351X, 11/2017, Volume 292, Issue 45, pp. 18618 - 18627
...(+) cytotoxic T lymphocytes. Individuals expressing the MHC class I molecule HLA-A2 produce cytotoxic T lymphocytes bearing T-cell receptors (TCRs... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Antibody Diversity | HLA-A2 Antigen - genetics | Viral Matrix Proteins - genetics | Antigens, Viral - metabolism | Humans | Receptors, Antigen, T-Cell, alpha-beta - chemistry | Antigens, Viral - genetics | Epitopes, T-Lymphocyte - genetics | Clonal Deletion | Immunodominant Epitopes - metabolism | Antigen-Antibody Complex - genetics | Influenza A virus - immunology | Viral Matrix Proteins - metabolism | Antigen-Antibody Complex - metabolism | Immunodominant Epitopes - genetics | Recombinant Proteins - metabolism | T-Lymphocytes, Cytotoxic - immunology | Protein Conformation, alpha-Helical | Peptide Fragments - metabolism | Immunodominant Epitopes - chemistry | T-Lymphocytes, Cytotoxic - virology | Models, Molecular | Recombinant Proteins - chemistry | Antibody Affinity | Antigens, Viral - chemistry | Receptors, Antigen, T-Cell, alpha-beta - genetics | Epitopes, T-Lymphocyte - chemistry | HLA-A2 Antigen - chemistry | Peptide Fragments - chemistry | Influenza A virus - metabolism | Hydrogen Bonding | T-Lymphocytes, Cytotoxic - metabolism | Viral Matrix Proteins - chemistry | Antigen-Antibody Complex - chemistry | T-Cell Antigen Receptor Specificity | Protein Conformation | HLA-A2 Antigen - metabolism | Mutation | Receptors, Antigen, T-Cell, alpha-beta - metabolism | T-Lymphocytes, Cytotoxic - cytology | Epitopes, T-Lymphocyte - metabolism | Amino Acid Substitution | Index Medicus | 60 APPLIED LIFE SCIENCES | T-cell receptor | Immunology | major histocompatibility complex (MHC) | crystal structure | influenza virus | surface plasmon resonance (SPR) | protein complex | epitope
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2004, Volume 172, Issue 4, pp. 2453 - 2460
textabstractIn the present study, the recognition of epitope variants of influenza A viruses by human CTL was investigated. To this end, human CD8(+) CTL... 
Influenza A virus/classification/immunology | Peptide Fragments/chemistry/immunology/metabolism | Humans | Protein Binding/immunology | Nucleoproteins/chemistry/immunology/metabolism | CD8-Positive T-Lymphocytes/chemistry/immunology/metabolism/virology | Cytotoxicity Tests, Immunologic/methods | Antigens, Viral/immunology/metabolism | Nucleocapsid Proteins | Epitopes, T-Lymphocyte/chemistry/immunology/metabolism | Viral Core Proteins/chemistry/immunology/metabolism | Middle aged | Research Support, Non-U.S. Gov't | Staining and Labeling | Leukocytes, Mononuclear/chemistry/immunology/virology | Adult | Clone Cells | HLA-B35 Antigen/chemistry/immunology/metabolism | Cell Line, Transformed | Serotyping | Life Sciences & Biomedicine | Immunology | Science & Technology | Nucleoproteins - chemistry | Antigens, Viral - metabolism | Middle Aged | Leukocytes, Mononuclear - virology | HLA-B35 Antigen - chemistry | Leukocytes, Mononuclear - immunology | Peptide Fragments - immunology | Viral Core Proteins - metabolism | CD8-Positive T-Lymphocytes - metabolism | HLA-B35 Antigen - metabolism | Influenza A virus - immunology | Cytotoxicity Tests, Immunologic - methods | Epitopes, T-Lymphocyte - immunology | Nucleoproteins - immunology | CD8-Positive T-Lymphocytes - chemistry | Viral Core Proteins - chemistry | Peptide Fragments - metabolism | HLA-B35 Antigen - immunology | Protein Binding - immunology | Epitopes, T-Lymphocyte - chemistry | Antigens, Viral - immunology | Leukocytes, Mononuclear - chemistry | Peptide Fragments - chemistry | CD8-Positive T-Lymphocytes - virology | Nucleoproteins - metabolism | Viral Core Proteins - immunology | CD8-Positive T-Lymphocytes - immunology | Influenza A virus - classification | Epitopes, T-Lymphocyte - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8577 - 8582
Immune responses can make protein therapeutics ineffective or even dangerous. We describe a general computational protein design method for reducing... 
T lymphocytes | Immune response | Immunodominant epitopes | Exotoxins | Medical treatment | Alleles | T lymphocyte epitopes | Epitopes | Genetic mutation | Epics | Biotherapeutics | Immunotoxin | Deimmunization | Machine learning | Rosetta | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Virulence Factors - genetics | Protein Engineering - methods | Humans | Molecular Sequence Data | Epitopes, T-Lymphocyte - genetics | Green Fluorescent Proteins - genetics | Virulence Factors - immunology | HLA Antigens - genetics | Support Vector Machine | Flow Cytometry | Bacterial Toxins - genetics | Immunotoxins - chemistry | Epitopes, T-Lymphocyte - immunology | Green Fluorescent Proteins - chemistry | ADP Ribose Transferases - chemistry | Protein Structure, Tertiary | ADP Ribose Transferases - immunology | Immunization | Immunotoxins - immunology | Exotoxins - chemistry | Bacterial Toxins - immunology | Exotoxins - immunology | Mice, Inbred C57BL | HLA Antigens - immunology | Models, Molecular | Spectrometry, Fluorescence | Virulence Factors - chemistry | Bacterial Toxins - chemistry | Proteins - immunology | Proteins - genetics | Sequence Homology, Amino Acid | ADP Ribose Transferases - genetics | Immunotoxins - genetics | Animals | Green Fluorescent Proteins - immunology | Exotoxins - genetics | Cell Line, Tumor | Mice | Computer-Aided Design | Proteins - chemistry | Microbiological research | Protein research | Peptides | Research | Pseudomonas | T cells | Health aspects | Index Medicus | biotherapeutics | Biological Sciences | Physical Sciences | immunotoxin | deimmunization | machine learning
Journal Article
Journal Article