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Science, ISSN 0036-8075, 2/2013, Volume 339, Issue 6119, pp. 587 - 590
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 48, pp. E11406 - E11414
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2007, Volume 25, Issue 33, pp. 5210 - 5217
Journal Article
Journal Article
Glycoconjugate Journal, ISSN 0282-0080, 04/2016, Volume 33, Issue 2, pp. 137 - 146
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2017, Volume 139, Issue 21, pp. 7318 - 7334
Journal Article
Synlett, ISSN 0936-5214, 05/2018, Volume 29, Issue 8, pp. 1076 - 1078
A new scalable synthesis of the common thiazole fragment (C-12-C-21 unit) of epothilone family of molecules (epothilone A-D) has been developed via... 
ixabepilone | epothilone | C | Wacker oxidation | unit of epothilone | thiazole fragment | C-12-C-21 unit of epothilone | REDUCTION | (-)-EPOTHILONE | CHEMISTRY, ORGANIC
Journal Article
Organic Letters, ISSN 1523-7060, 12/2012, Volume 14, Issue 24, pp. 6354 - 6357
An efficient total synthesis of (-)-epothilone B has been achieved in ca. 8% yield over 11 steps from 9 (or 10 steps from 7/8), which features a... 
CHEMISTRY, ORGANIC | EPOTHILONE-B | Molecular Structure | Epothilones - chemical synthesis | Cyclization | Epothilones - chemistry | Stereoisomerism | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 35, pp. 13157 - 13162
Journal Article
Annals of Oncology, ISSN 0923-7534, 09/2011, Volume 22, Issue 9, pp. 2144 - 2149
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 1/2009, Volume 63, Issue 2, pp. 201 - 212
Ixabepilone, a semisynthetic analog of natural epothilone B, was developed for use in cancer treatment. This study extends previous findings regarding the... 
Antineoplastic | Epothilone | Oncology | Breast cancer | Taxane | Drug resistance | P-glycoprotein | Biomedicine | Tubulin | Cancer Research | Ixabepilone | Pharmacology/Toxicology | Pharmacokinetics | ADVANCED SOLID TUMORS | TARGET ENGAGEMENT | PHASE-II | DESOXYEPOTHILONE-B | EPOTHILONE-B-ANALOG | MICROTUBULE-STABILIZING AGENTS | II CLINICAL-TRIAL | ONCOLOGY | METASTATIC BREAST-CANCER | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | MULTIDRUG-RESISTANCE | Neoplasms - metabolism | Neoplasm Transplantation | Area Under Curve | Tubulin Modulators - pharmacology | Drug Resistance, Multiple - drug effects | Humans | Epothilones - pharmacology | Antineoplastic Agents - therapeutic use | Chromatography, High Pressure Liquid | Epothilones - therapeutic use | Mass Spectrometry | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Tubulin Modulators - pharmacokinetics | Epothilones - pharmacokinetics | Mice, SCID | Mice, Inbred C3H | Tubulin Modulators - therapeutic use | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Drug Resistance, Neoplasm - drug effects | Drug resistance in microorganisms | Care and treatment | Oncology, Experimental | Development and progression | Research | Tubulins | Antineoplastic agents | Antimitotic agents | Colon cancer | Analysis | Gastrointestinal diseases | Tumors | Cancer | Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2009, Volume 27, Issue 4, pp. 526 - 534
Journal Article