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Food and Chemical Toxicology, ISSN 0278-6915, 10/2013, Volume 60, pp. 404 - 412
Non-alcoholic fatty liver disease (NAFLD) is defined as excess of fat in the liver. We investigated the effects of black soybean on the cholesterol metabolism... 
Cholesterol accumulation | Insulin resistance | Antioxidative activity | Mice | Non-alcoholic fatty liver disease | ABCA1 EXPRESSION | METABOLIC SYNDROME | LIPID-METABOLISM | FOOD SCIENCE & TECHNOLOGY | RATS | PPAR | INSULIN-RESISTANCE | SOY ISOFLAVONES | TOXICOLOGY | ROSIGLITAZONE | STRESS | AMP-Activated Protein Kinases - metabolism | Transcriptome | Diet, High-Fat - adverse effects | Male | PPAR gamma - metabolism | RNA, Messenger - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Hydroxymethylglutaryl CoA Reductases - metabolism | Liver - drug effects | Non-alcoholic Fatty Liver Disease | Adiponectin - secretion | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Superoxide Dismutase - metabolism | PPAR gamma - genetics | Malondialdehyde - metabolism | Fatty Liver - diet therapy | Isoflavones - blood | Signal Transduction | Equol - blood | Liver - metabolism | RNA, Messenger - genetics | Bile Acids and Salts - metabolism | Nitric Oxide | Cholesterol - metabolism | Mice, Inbred ICR | Adiponectin - blood | Catalase - metabolism | Soybeans - chemistry | Animals | Lipid Metabolism - drug effects | Triglycerides - blood | Oxidative Stress - drug effects | Blood Glucose - metabolism | Hydroxymethylglutaryl CoA Reductases - genetics | Cholesterol | Liver diseases | Soybean | Index Medicus
Journal Article
Pharmacological Research, ISSN 1043-6618, 03/2013, Volume 69, Issue 1, pp. 21 - 31
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 04/2018, Volume 82, Issue 4, pp. 600 - 610
Several dietary flavonoids exhibit anti-oxidative, anti-inflammatory, and anti-osteoporotic activities relevant to prevention of chronic diseases, including... 
l-DZNR, NADP(H)-dependent daidzein reductase | LPH: lactase-phlorizin hydrolase | PCA: 3,4-dihydroxybenzoic (protocatechuic) acid | microbial metabolism | DHD: dihydrodaidzein | Q3G: quercetin 3-O-glucoside | OVX: ovariectomized | l-DDRC: DHD racemase | Flavonoid | THD: tetrahydrodaidzein | ALDH: aldehyde dehydrogenase | O-DMA: O-desmethylangolensin | OPAC: 3-hydroxyphenylacetic acid | DOPAC: 3,4-dihydroxyphenylacetic acid | FOS: fructooligosaccharides | equol | Nrf2: NFE2-related factor 2 | l-THDR: THD reductase | Keap1: Kelch-like erythroid cell-derived protein 1 | l-DHDR: DHD reductase | phase II metabolism | COMT: catechol-O-methyltransferases | MCT: monocarboxylic acid transporter | Q4ʹG: quercetin 4ʹ-O-glucoside | ring-fission products | AhR: aryl hydrocarbon receptor | CBG: cytosolic β-glucosidase | SGLT1: sodium-glucose co-transporter type 1 | SULT: sulfotransferases, UGT: uridine-5ʹ-diphosphate-glucuronosyltransferases | Ring-fission products | Phase II metabolism | Microbial metabolism | Equol | EQUOL-PRODUCING BACTERIUM | LACTOCOCCUS STRAIN 20-92 | BONE-MINERAL DENSITY | LACTASE-PHLORHIZIN HYDROLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | INDUCED LIPID-PEROXIDATION | S-EQUOL | DEPENDENT GLUCOSE-TRANSPORTER | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESTROGEN-RECEPTOR-ALPHA | CHEMISTRY, APPLIED | CORONARY-HEART-DISEASE | OVARIECTOMIZED MICE
Journal Article
Nutrients, ISSN 2072-6643, 03/2017, Volume 9, Issue 3, p. 207
Estrogen deficiency has been well characterized in inflammatory disorders including neuroinflammation. Daidzein, a dietary alternative phytoestrogen found in... 
Phytoestrogen | Neuroprotection | Neuroinflammation | Equol | Apoptosis | OXIDATIVE STRESS | FOCAL CEREBRAL-ISCHEMIA | apoptosis | FACTOR-KAPPA-B | PHYTOESTROGENS | GENISTEIN | THERAPEUTIC SIGNIFICANCE | phytoestrogen | ESTROGEN-RECEPTOR-BETA | ISOFLAVONES | NUTRITION & DIETETICS | neuroinflammation | neuroprotection | PARKINSONS-DISEASE | Tumor Necrosis Factor-alpha - metabolism | Central Nervous System - metabolism | Apoptosis - drug effects | Isoflavones - pharmacology | NF-kappa B - metabolism | Neurons - cytology | Equol - pharmacology | Neuroprotective Agents - pharmacology | Cyclooxygenase 2 - genetics | Neurons - metabolism | Neurons - drug effects | Interleukin-6 - metabolism | Astrocytes - cytology | Microglia - cytology | Astrocytes - drug effects | Cell Survival - drug effects | Lipopolysaccharides - toxicity | Microglia - drug effects | Down-Regulation | Rats | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - metabolism | Dinoprostone - metabolism | Animals | Central Nervous System - cytology | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Central Nervous System - drug effects | Mitogen-Activated Protein Kinases - genetics | Mice | Nitric Oxide - metabolism | Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Synthase Type II - metabolism | Soybeans | Estrogens | Central nervous system | Prostaglandin E2 | Nerve growth factor | Kinases | Lipopolysaccharides | Prostaglandin endoperoxide synthase | Interleukin 6 | Proteins | Neurodegeneration | Transcription activation | Toll-like receptors | Microglial cells | Tumor necrosis factor-TNF | Neurotrophins | Isoflavones | Secretion | Axonogenesis | Astrocytes | MAP kinase | TLR4 protein | Nitric-oxide synthase | Microglia | Diet | Protein kinase | Nitric oxide | Daidzein | In vitro methods and tests
Journal Article
Chirality, ISSN 0899-0042, 09/2014, Volume 26, Issue 9, pp. 434 - 437
ABSTRACT To elucidate the hitherto unknown absolute configuration of (−)–O‐desmethylangolensin ((−)–O‐DMA), an intestinal bacterial metabolite produced from... 
daidzein | equol | isoflavone | bioconversion | O‐DMA | TD‐DFT | chiroptical | computation | O-DMA | TD-DFT | CHEMISTRY, ANALYTICAL | CHEMISTRY, MEDICINAL | CONVERSION | CHEMISTRY, ORGANIC | IDENTIFICATION | S-EQUOL | C-RING | ISOFLAVONES | IN-VITRO | MODELS | RECEPTOR-BETA | PHARMACOLOGY & PHARMACY | SOY | BINDING | Density functionals | Physiological aspects | Isoflavones | Exchange | Ethanol | Mathematical analysis | Chirality | Dichroism | Ethyl alcohol | Electronics | Bacteria
Journal Article
American Journal of Clinical Nutrition, ISSN 0002-9165, 09/2017, Volume 106, Issue 3, pp. 909 - 920
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement... 
Isoflavone | Probiotics | Equol | Postmenopause | Bone density | Bioavailability | Bone turnover | Osteopenia | osteopenia | equol | bone density | PREVENTION | RISK | FORMONONETIN | bone turnover | OVARIAN-CANCER | HORMONE REPLACEMENT THERAPY | PHYTOESTROGENS | OSTEOPOROSIS | RED-CLOVER | isoflavone | MINERAL DENSITY | NUTRITION & DIETETICS | bioavailability | SOY ISOFLAVONES | postmenopause | probiotics | Collagen Type I - blood | Intestines - drug effects | Peptides - blood | Estrogens - deficiency | Plant Extracts - pharmacology | Humans | Isoflavones - pharmacology | Middle Aged | Osteoporosis, Postmenopausal - metabolism | Biological Availability | Intestines - metabolism | Bone Remodeling - drug effects | Bone and Bones - drug effects | Trifolium - chemistry | Bone Diseases, Metabolic - drug therapy | Selective Estrogen Receptor Modulators - therapeutic use | Bone and Bones - metabolism | Female | Phytotherapy | Estrogens - metabolism | Osteoporosis, Postmenopausal - prevention & control | Isoflavones - blood | Double-Blind Method | Isoflavones - pharmacokinetics | Gastrointestinal Microbiome | Bone Density Conservation Agents - therapeutic use | Bone Density Conservation Agents - pharmacology | Bone Diseases, Metabolic - metabolism | Bone Density - drug effects | Intestines - microbiology | Probiotics - therapeutic use | Isoflavones - therapeutic use | Plant Extracts - therapeutic use | Selective Estrogen Receptor Modulators - pharmacology | Drug Combinations | Diet therapy | Red clover | Nutritional aspects | Postmenopausal women | Food and nutrition | Health aspects | Isoflavones | Materia medica, Vegetable | Plant extracts | Index Medicus | Abridged Index Medicus
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 01/2016, Volume 80, Issue 1, pp. 199 - 202
Journal Article