X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (6358) 6358
humans (6057) 6057
life sciences & biomedicine (5726) 5726
erbb receptors - metabolism (4942) 4942
animals (4207) 4207
female (2438) 2438
oncology (1992) 1992
erbb receptors - genetics (1968) 1968
mice (1924) 1924
epidermal growth factor (1857) 1857
male (1747) 1747
signal transduction (1723) 1723
phosphorylation (1542) 1542
biochemistry & molecular biology (1491) 1491
cell biology (1447) 1447
cell line, tumor (1417) 1417
erbb receptors - antagonists & inhibitors (1124) 1124
epidermal growth factor - metabolism (1115) 1115
cell line (1028) 1028
middle aged (1012) 1012
mutation (997) 997
rats (932) 932
cancer (907) 907
egfr (854) 854
epidermal growth factor receptors (829) 829
aged (826) 826
epidermal growth factor - pharmacology (819) 819
research article (789) 789
adult (779) 779
proteins (779) 779
immunohistochemistry (760) 760
cells, cultured (731) 731
gene expression (718) 718
tumor cells, cultured (712) 712
research (694) 694
epidermal growth factor receptor (693) 693
kinases (684) 684
receptors (635) 635
erbb receptors (617) 617
signal transduction - drug effects (603) 603
antineoplastic agents - pharmacology (598) 598
science & technology - other topics (597) 597
tumors (593) 593
ligands (592) 592
receptor, erbb-2 - metabolism (587) 587
kinetics (556) 556
multidisciplinary sciences (554) 554
molecular sequence data (551) 551
apoptosis (544) 544
lung neoplasms - genetics (516) 516
amino acid sequence (508) 508
cell proliferation (505) 505
protein kinase inhibitors - pharmacology (499) 499
tyrosine (498) 498
prognosis (492) 492
breast cancer (488) 488
cell proliferation - drug effects (479) 479
analysis (475) 475
lung cancer (471) 471
lung neoplasms - metabolism (467) 467
lung neoplasms - drug therapy (464) 464
lung neoplasms - pathology (462) 462
gene expression regulation, neoplastic (447) 447
growth factors (441) 441
breast neoplasms - metabolism (438) 438
erbb receptors - physiology (432) 432
transfection (427) 427
pharmacology & pharmacy (420) 420
protein binding (417) 417
mice, nude (413) 413
genetic aspects (410) 410
protein-tyrosine kinases - metabolism (403) 403
antineoplastic agents - therapeutic use (402) 402
receptors, cell surface - metabolism (399) 399
cell division - drug effects (396) 396
aged, 80 and over (385) 385
signal transduction - physiology (372) 372
biology (368) 368
cell growth (365) 365
receptor, epidermal growth factor - metabolism (353) 353
erbb receptors - biosynthesis (344) 344
medicine (340) 340
developmental biology (338) 338
cell membrane - metabolism (336) 336
proto-oncogene proteins - metabolism (336) 336
blotting, western (333) 333
erbb receptors - analysis (329) 329
metastasis (329) 329
binding sites (328) 328
physiological aspects (327) 327
breast neoplasms - pathology (326) 326
rna, messenger - metabolism (323) 323
quinazolines - pharmacology (322) 322
erbb receptors - drug effects (320) 320
tyrosine - metabolism (310) 310
apoptosis - drug effects (309) 309
enzyme activation (307) 307
protein kinase inhibitors - therapeutic use (307) 307
base sequence (306) 306
xenograft model antitumor assays (306) 306
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (8253) 8253
Japanese (93) 93
Chinese (54) 54
French (8) 8
Spanish (8) 8
Russian (5) 5
German (4) 4
Czech (2) 2
Hungarian (2) 2
Norwegian (2) 2
Portuguese (2) 2
Croatian (1) 1
Korean (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


2008, Cancer drug discovery and development, ISBN 9781597453561, xi, 393
The epidermal growth factor (EGF) receptor and its downstream signal transduction networks have been implicated in the ontology and maintenance of tumor tissues... 
drug therapy | Signal Transduction | drug effects | metabolism | Neoplasms | antagonists & inhibitors | Receptor, Epidermal Growth Factor | Chemotherapy | Treatment | Cancer
Book
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 11/2014, Volume 111, Issue 45, pp. E4869 - E4877
The human FGF receptors (FGFRs) play critical roles in various human cancers, and several FGFR inhibitors are currently under clinical investigation... 
Structure-based drug design | Drug discovery | Cancer drug resistance | Kinase inhibitor | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Receptor, Fibroblast Growth Factor, Type 4 - chemistry | Receptor, Fibroblast Growth Factor, Type 4 - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - chemistry | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Humans | ErbB Receptors - genetics | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Crystallography, X-Ray | Structure-Activity Relationship | Mutation, Missense | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Protein Kinase Inhibitors - chemistry | Neoplasms - genetics | Receptor, Fibroblast Growth Factor, Type 2 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Receptor, Fibroblast Growth Factor, Type 4 - genetics | Binding Sites | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Neoplasms - enzymology | Antineoplastic Agents - chemistry | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | ErbB Receptors - chemistry | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Receptor, Fibroblast Growth Factor, Type 1 - chemistry | Neoplasms - pathology | Receptor, Fibroblast Growth Factor, Type 4 - antagonists & inhibitors | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Amino Acid Substitution | Drug Resistance, Neoplasm - drug effects | Index Medicus | Biological Sciences | kinase inhibitor | structure-based drug design | cancer drug resistance | PNAS Plus | drug discovery
Journal Article
Cancer Letters, ISSN 0304-3835, 2017, Volume 393, pp. 52 - 59
.... At least one ErbB family member was expressed in 88% of tumors. To exploit ErbB dysregulation in this disease, patient T-cells were engineered by retroviral transduction to express a panErbB-targeted chimeric antigen receptor (CAR... 
Hematology, Oncology and Palliative Medicine | Mesothelioma | Chimeric antigen receptor | Lung cancer | Epidermal growth factor receptor | Life Sciences & Biomedicine | Oncology | Science & Technology | Mesothelioma - immunology | Receptor, ErbB-4 - metabolism | Pleural Neoplasms - genetics | Coculture Techniques | Humans | Lung Neoplasms - metabolism | Receptor, ErbB-2 - metabolism | Recombinant Fusion Proteins - metabolism | T-Lymphocytes - transplantation | Pleural Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | T-Lymphocytes - metabolism | Time Factors | Lymphocytes, Tumor-Infiltrating - metabolism | Receptors, Antigen, T-Cell - immunology | Lung Neoplasms - genetics | Immunotherapy, Adoptive - methods | Mesothelioma - therapy | Pleural Neoplasms - immunology | ErbB Receptors - metabolism | Transduction, Genetic | Receptors, Antigen, T-Cell - metabolism | Interleukin-4 - metabolism | Lymphocytes, Tumor-Infiltrating - transplantation | Lung Neoplasms - therapy | Mesothelioma - genetics | Tumor Burden | Mice, SCID | Pleural Neoplasms - therapy | Xenograft Model Antitumor Assays | Interleukin-4 - immunology | Lung Neoplasms - immunology | Animals | Mesothelioma - metabolism | ErbB Receptors - immunology | Cell Line, Tumor | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Genetic Therapy - methods | Lymphocytes, Tumor-Infiltrating - immunology | Interleukins | T cells | Immunotherapy | Genetically modified organisms | Antigens | Epidermal growth factor | Genetic engineering | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 07/2007, Volume 448, Issue 7151, pp. 362 - 365
... to be non-migratory. Two receptor tyrosine kinases (RTKs), PDGF- and VEGF-related receptor (PVR) and epidermal growth factor receptor (EGFR), are guidance receptors... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Kinases - metabolism | Protein Kinases - genetics | Adaptor Proteins, Vesicular Transport - genetics | ErbB Receptors - genetics | rac GTP-Binding Proteins - metabolism | Drosophila Proteins - metabolism | raf Kinases - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Receptors, Invertebrate Peptide - genetics | Receptors, Vascular Endothelial Growth Factor - metabolism | raf Kinases - genetics | Genes, Essential - genetics | Shc Signaling Adaptor Proteins | Phospholipase C gamma - metabolism | ErbB Receptors - metabolism | Signal Transduction | Drosophila melanogaster - cytology | Mutation - genetics | Animals | Receptors, Platelet-Derived Growth Factor - metabolism | Adaptor Proteins, Signal Transducing - genetics | Receptors, Invertebrate Peptide - metabolism | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cell Movement | Mitogen-Activated Protein Kinases - metabolism | Genetic aspects | Motility | Research | Drosophila | Cell migration | Cells | Proteins | Signal transduction | Cellular biology | Insects | Fish | Genetics | Cell adhesion & migration | Receptors | Pathways | Migration | Clusters | Kinases | Signalling | Borders | Index Medicus | Life Sciences
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 08/2013, Volume 288, Issue 32, pp. 22942 - 22960
TGR5 is a G protein-coupled receptor that mediates bile acid (BA) effects on energy balance, inflammation, digestion, and sensation... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cholagogues and Choleretics - pharmacology | Phenylalanine - analogs & derivatives | Receptors, G-Protein-Coupled - metabolism | Membrane Microdomains - metabolism | Phenylalanine - pharmacology | Humans | ErbB Receptors - genetics | Oleanolic Acid - pharmacology | Arrestins - genetics | Protein Transport - physiology | Protein Transport - drug effects | G-Protein-Coupled Receptor Kinase 2 - genetics | G-Protein-Coupled Receptor Kinase 2 - metabolism | Arrestins - metabolism | beta-Cyclodextrins - pharmacology | Endosomes - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | HEK293 Cells | Antineoplastic Agents - pharmacology | Cyclic AMP - genetics | Cyclic AMP - metabolism | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Endosomes - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Endocytosis - drug effects | Enzyme Inhibitors - pharmacology | Thiophenes - pharmacology | Tyrphostins - pharmacology | Endocytosis - physiology | Arrestins - antagonists & inhibitors | G-Protein-Coupled Receptor Kinase 5 - metabolism | Deoxycholic Acid - pharmacology | Mitogen-Activated Protein Kinase 3 - metabolism | beta-Arrestin 2 | beta-Arrestin 1 | beta-Arrestins | Receptors, G-Protein-Coupled - genetics | Quinazolines - pharmacology | G-Protein-Coupled Receptor Kinase 5 - genetics | Membrane Microdomains - genetics | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | Lipid Raft | Bile Acid | Endocytosis | G Protein-coupled Receptors (GPCR) | Arrestin | Signal Transduction
Journal Article
Nature (London), ISSN 1476-4687, 05/2018, Volume 557, Issue 7707, pp. 724 - 728
...) mouse model of multiple sclerosis. Microglia-derived TGFa acts via the ErbB1 receptor in astrocytes to limit their pathogenic activities and EAE development... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Inflammation - pathology | Microglia - metabolism | Central Nervous System - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Astrocytes - pathology | Central Nervous System - pathology | Vascular Endothelial Growth Factor B - biosynthesis | Tryptophan - metabolism | Lipopolysaccharide Receptors - metabolism | Inflammation - metabolism | Tryptophan - deficiency | Microglia - pathology | Receptors, Aryl Hydrocarbon - metabolism | Female | Transforming Growth Factor alpha - metabolism | Central Nervous System - microbiology | Disease Models, Animal | Encephalomyelitis, Autoimmune, Experimental - microbiology | Multiple Sclerosis - metabolism | Transforming Growth Factor alpha - biosynthesis | Symbiosis | Inflammation - microbiology | Encephalomyelitis, Autoimmune, Experimental - pathology | ErbB Receptors - metabolism | Mice, Inbred C57BL | Cells, Cultured | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Animals | Vascular Endothelial Growth Factor B - metabolism | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Multiple Sclerosis - pathology | Inflammation - prevention & control | Mice | Astrocytes - metabolism | Physiological aspects | Microbiological research | Metabolites | Transforming growth factors | Astrocytes | Vascular endothelial growth factor | Regulators | Multiple sclerosis | Transcription | Central nervous system | Hydrocarbons | Nervous system | CD14 antigen | Recruitment | Angiogenesis | Signal transduction | Neurotoxicity | Microorganisms | Neurodegeneration | Aromatic compounds | Bone marrow | ErbB-1 protein | Tryptophan | Inflammation | Gene expression | Experimental allergic encephalomyelitis | Microglia | Neurological diseases | Diet | Lymphocytes B | Flora | Spinal cord injuries | Alzheimers disease | Index Medicus | Life Sciences | Immunology
Journal Article
Cancer letters, ISSN 0304-3835, 08/2017, Volume 400, pp. 9 - 17
Abstract Inflammation plays a central role in prostate cancer (PCa) development through significant crosstalk between the COX2- ErbB family receptor network and androgen receptor (AR... 
Hematology, Oncology and Palliative Medicine | Celecoxib | ErbB receptors | hnRNP K | Prostate cancer | Chemoprevention | Androgen receptor | Life Sciences & Biomedicine | Oncology | Science & Technology | Receptor, Epidermal Growth Factor - genetics | Receptor, ErbB-3 - metabolism | Apoptosis - drug effects | Heterogeneous-Nuclear Ribonucleoprotein K | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Receptor, ErbB-2 - metabolism | Male | Dose-Response Relationship, Drug | Receptor, Epidermal Growth Factor - metabolism | Prostatic Neoplasms - genetics | Receptors, Androgen - drug effects | Time Factors | Proteolysis | Amphiregulin - metabolism | Ribonucleoproteins - genetics | Transcription, Genetic | Antineoplastic Agents - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Prostatic Neoplasms - drug therapy | Amphiregulin - genetics | Prostatic Neoplasms - pathology | Epidermal Growth Factor - genetics | Ubiquitin-Protein Ligases - metabolism | Androgen Antagonists - pharmacology | Receptor, ErbB-3 - antagonists & inhibitors | Epidermal Growth Factor - metabolism | Ribonucleoproteins - metabolism | Celecoxib - pharmacology | Receptors, Androgen - genetics | Signal Transduction - drug effects | Prostatic Neoplasms - enzymology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Prevention | COX-2 inhibitors | Epidermal growth factor | Ligases | Development and progression | Angiogenesis inhibitors | Genetic translation | Cancer | Protein binding | Index Medicus
Journal Article
Endocrinology (Philadelphia), ISSN 0013-7227, 10/2017, Volume 158, Issue 10, pp. 3647 - 3660
.... Our experimental results suggest gonadotropins promote differential expression of NRG1 and erbB receptors in granulosa cells (GCs... 
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Phosphoproteins - drug effects | Receptor, ErbB-3 - metabolism | Apoptosis - drug effects | Caspase 3 - metabolism | Receptor, ErbB-2 - metabolism | Ovary - cytology | Phosphoproteins - metabolism | Gonadotropins - pharmacology | Follicular Fluid | Granulosa Cells - drug effects | Granulosa Cells - metabolism | bcl-X Protein - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Receptor, ErbB-3 - drug effects | Caspase 3 - drug effects | Female | Ovary - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Receptor, ErbB-2 - drug effects | Ovary - metabolism | ErbB Receptors - metabolism | Cell Survival | Ovarian Follicle - growth & development | Rats | Protein Kinase C - antagonists & inhibitors | Neuregulin-1 - pharmacology | Theca Cells | ErbB Receptors - drug effects | Neuregulin-1 - drug effects | Rats, Sprague-Dawley | Animals | Neuregulin-1 - metabolism | Proto-Oncogene Proteins c-bcl-2 - drug effects | In Vitro Techniques | bcl-X Protein - metabolism | Staurosporine - pharmacology | Proto-Oncogene Proteins c-akt - drug effects | Protein kinase C | Neuregulin 1 | Staurosporine | Crosstalk | Intracellular signalling | Hormones | Estrus cycle | Kinases | Caspase-3 | Proteins | Receptors | Epidermal growth factor | Rodents | Granulosa cells | Neuregulin | Estrus | Cell survival | Maturation | ErbB protein | Caspase | Pituitary (anterior) | Gonadotropins | ErbB-3 protein | Ovaries | Follicular fluid | Secretions | Survival | ErbB-2 protein | Cell death | Survival factor | Steroid hormones | Theca | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article