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Journal Article
BBA - Biomembranes, ISSN 0005-2736, 10/2015, Volume 1848, Issue 10, pp. 2188 - 2199
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2017, Volume 58, Issue 12, pp. 2310 - 2323
Ergosterol biosynthesis pathways essential to pathogenic protozoa growth and absent from the human host offer new chokepoint targets. Here, we present... 
Ergosterol biosynthesis inhibitors | Phytosterol biosynthesis | Anti-amoeba drugs | Sterol C24-methyltransferase | Acanthamoeba | anti-amoeba drugs | DELTA(25)-OLEFIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DELTA(24)-STEROL METHYL TRANSFERASE | TRYPANOSOMA SCHIZOTRYPANUM CRUZI | ACANTHAMOEBA-KERATITIS | MECHANISTIC ANALYSIS | sterol C24-methyltransferase | EVOLUTION | ERGOSTEROL BIOSYNTHESIS | phytosterol biosynthesis | GROWTH | AGENTS | INHIBITORS | ergosterol biosynthesis inhibitors | Sterols - metabolism | Triterpenes - pharmacology | Protozoan Proteins - antagonists & inhibitors | Epithelial Cells - drug effects | Humans | Methyltransferases - metabolism | Methyltransferases - genetics | Substrate Specificity | Lanosterol - pharmacology | Lanosterol - analogs & derivatives | Protozoan Proteins - genetics | Phytosterols - pharmacology | Protozoan Proteins - metabolism | Acanthamoeba - enzymology | Drug Design | Acanthamoeba - genetics | Lanosterol - metabolism | Cholestadienols - metabolism | Epithelial Cells - cytology | Triterpenes - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Cell Survival - drug effects | Gene Expression | Acanthamoeba - drug effects | Kidney - cytology | Recombinant Proteins - genetics | Sequence Homology, Amino Acid | Sequence Alignment | Methyltransferases - antagonists & inhibitors | Phytosterols - metabolism | Protein Binding | Kinetics | Cholestadienols - pharmacology | Ergosterol | Protozoa | Sterols | Methyltransferase | Voriconazole | Substrate preferences | Biosynthesis | Suicide | Drug development | Cholesterol | Intermediates
Journal Article
Marine Drugs, ISSN 1660-3397, 05/2017, Volume 15, Issue 5, p. 139
Journal Article