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1. Pharmacokinetics of ergotamine with special emphasis on bioavailability
by Ibraheem, Jaafar
1985, ISBN 9789155417307, 48
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2. Full Text Structural Features for Functional Selectivity at Serotonin Receptors
by Daniel Wacker and Chong Wang and Vsevolod Katritch and Gye Won Han and Xi-Ping Huang and Eyal Vardy and John D. McCorvy and Yi Jiang and Meihua Chu and Fai Yiu Siu and Wei Liu and H. Eric Xu and Vadim Cherezov and Bryan L. Roth and Raymond C. Stevens
Science, ISSN 0036-8075, 5/2013, Volume 340, Issue 6132, pp. 615 - 619
Drugs active at G protein–coupled receptors (GPCRs) can differentially modulate either canonical or noncanonical signaling pathways via a phenomenon known as... 
Receptors | Sand sheets | Hydrogen bonds | Serotonin receptors | REPORTS | Agonists | Ligands | Biochemistry | Pharmacology | Grants | Crystal structure | PATHWAYS | PROTEIN-COUPLED RECEPTOR | AGONISTS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | Receptor, Serotonin, 5-HT2B - metabolism | Humans | Lysergic Acid Diethylamide - metabolism | Molecular Sequence Data | Crystallography, X-Ray | Arrestins - metabolism | Ergotamine - chemistry | Ergotamine - metabolism | HEK293 Cells | Receptor, Serotonin, 5-HT1B - metabolism | Binding Sites | Arrestin - metabolism | Amino Acid Sequence | Protein Structure, Secondary | Signal Transduction | Models, Molecular | Lysergic Acid Diethylamide - chemistry | Receptors, Serotonin - chemistry | Ergolines - chemistry | Receptors, Serotonin - metabolism | Amino Acid Motifs | Ergolines - metabolism | Receptor, Serotonin, 5-HT2B - chemistry | beta-Arrestins | Receptor, Serotonin, 5-HT1B - chemistry | Protein Conformation | Serotonin | Drug interactions | Physiological aspects | Ergotamine | Dosage and administration | G proteins | Research | Neurons
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3. Full Text History of the use of ergotamine and dihydroergotamine in migraine from 1906 and onward
by Tfelt-Hansen, PC and Koehler, PJ
Cephalalgia, ISSN 0333-1024, 08/2008, Volume 28, Issue 8, pp. 877 - 886
Dale showed in 1906 in a seminal work that ergot inhibits the pressor effect of adrenaline. Stoll at Sandoz isolated ergotamine from ergot in 1918. Based on... 
ergotamine | Dihydroergotamine | migraine | migraine pathophysiology | ergotism | ergotamine overuse headache | Dihydro- Ergotamine | Ergotamine overuse headache | Ergotamine | Ergotism | Migraine pathophysiology | Migraine | AMERICAN EXPERIENCE | TARTRATE | BLOOD-FLOW | NEUROSCIENCES | CLINICAL NEUROLOGY | PROTEASE INHIBITOR | THERAPY | dihydroergotamine | HEADACHE | 5-HT RECEPTORS | CLINICAL-TRIALS | ALKALOIDS | Clinical Trials as Topic - history | Vasoconstrictor Agents - therapeutic use | History, 21st Century | Internationality | History, 20th Century | Humans | Migraine Disorders - history | Ergotamine - therapeutic use | Ergotamine - history | Migraine Disorders - drug therapy | Vasoconstrictor Agents - history
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4. Full Text Structural Basis for Molecular Recognition at Serotonin Receptors
by Chong Wang and Yi Jiang and Jinming Ma and Huixian Wu and Daniel Wacker and Vsevolod Katritch and Gye Won Han and Wei Liu and Xi-Ping Huang and Eyal Vardy and John D. McCorvy and Xiang Gao and X. Edward Zhou and Karsten Melcher and Chenghai Zhang and Fang Bai and Huaiyu Yang and Linlin Yang and Hualiang Jiang and Bryan L. Roth and Vadim Cherezov and Raymond C. Stevens and H. Eric Xu and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Science, ISSN 0036-8075, 5/2013, Volume 340, Issue 6132, pp. 610 - 614
Serotonin or 5-hydroxytryptamine (5-HT) regulates a wide spectrum of human physiology through the 5-HT receptor family. We report the crystal structures of the... 
Receptors | Sand sheets | Hydrogen bonds | Serotonin receptors | REPORTS | Ligands | Agonists | Indoles | Grants | LSD | Binding sites | LIGANDS | PROTEIN-COUPLED RECEPTOR | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | MUTATION | CARDIAC VALVULOPATHY | VALVULAR HEART-DISEASE | SCHIZOPHRENIA | DISORDERS | FENFLURAMINE | AGONIST | Pindolol - chemistry | Humans | Lysergic Acid Diethylamide - metabolism | Molecular Sequence Data | Crystallography, X-Ray | Propranolol - metabolism | Serotonin 5-HT1 Receptor Agonists - chemistry | Ergotamine - chemistry | Ergotamine - metabolism | Receptor, Serotonin, 5-HT1B - genetics | Receptor, Serotonin, 5-HT1B - metabolism | Binding Sites | Amino Acid Sequence | Tryptamines - chemistry | Norfenfluramine - metabolism | Dihydroergotamine - chemistry | Protein Structure, Secondary | Models, Molecular | Dihydroergotamine - metabolism | Lysergic Acid Diethylamide - chemistry | Propranolol - chemistry | Serotonin 5-HT1 Receptor Agonists - metabolism | Pindolol - analogs & derivatives | Protein Folding | Norfenfluramine - chemistry | Hydrogen Bonding | Mutagenesis | Tryptamines - metabolism | Receptor, Serotonin, 5-HT1B - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Conformation | Molecular Docking Simulation | Pindolol - metabolism | Physiological aspects | Research | G proteins | Serotonin | Molecular biology | Ligands (Biochemistry) | Neurons | Index Medicus
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5. The acute antimigraine efficacy of triptans and ergotamine
by Ikeda, Ritsuko
Japanese Journal of Anesthesiology, ISSN 0021-4892, 07/2018, Volume 67, Issue 7, pp. 715 - 723
Triptans | Migraine disorders | Ergotamine
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6. Full Text Dihydroergotamine, Ergotamine, Methysergide and Sumatriptan – Basic Science in Relation to Migraine Treatment
by Dahlöf, Carl and Maassen Van Den Brink, Antoinette
Headache: The Journal of Head and Face Pain, ISSN 0017-8748, 04/2012, Volume 52, Issue 4, pp. 707 - 714
The 5‐hydroxytryptamine (5‐HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5‐HT1B, 5‐HT1D, and... 
ergotamine | migraine | headache | sumatriptan | TRIGEMINOVASCULAR SYSTEM | EFFICACY | SAFETY | EXTERNAL CAROTID VASOCONSTRICTION | TRIGEMINAL SYSTEM | CLINICAL NEUROLOGY | PGE RELEASE | IN-VITRO | PHARMACOLOGY | RECEPTOR AGONIST | RAT DURA-MATER | Dihydroergotamine - therapeutic use | Ergotamine - pharmacokinetics | Methysergide - pharmacokinetics | Dihydroergotamine - chemistry | Humans | Sumatriptan - therapeutic use | Dihydroergotamine - pharmacokinetics | Ergotamine - therapeutic use | Methysergide - therapeutic use | Treatment Outcome | Migraine Disorders - drug therapy | Migraine Disorders - metabolism | Animals | Ergotamine - chemistry | Sumatriptan - pharmacokinetics | Methysergide - chemistry | Sumatriptan - chemistry | Sumatriptan | Migraine | Ergotamine | Drug therapy | Medicine, Preventive | Methysergide | Preventive health services | Medical research | Drugs | Headache | Side effects | Serotonin | Serotonin S1 receptors
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7. Full Text Sensitive ergotamine determination in pharmaceuticals and biological samples using cloud point preconcentration and spectrofluorimetric detection
by Wang, Chien C and Fernández, Liliana P and Gómez, María Roxana
Analytica Chimica Acta, ISSN 0003-2670, 03/2013, Volume 768, Issue 1, pp. 90 - 95
► A highly efficient cloud point extraction method was developed for ergotamine. ► Direct gel-state fluorescence determination was performed after extraction.... 
Urine | Ergotamine | Cloud point extraction | Spectrofluorimetry | Saliva | Pharmaceuticals | COMBINED METHODOLOGY | CHEMISTRY, ANALYTICAL | TARTRATE | CHROMATOGRAPHY | MEDIATED SEPARATION | EXTRACTION | ALKALOIDS | Ergotamine - analysis | Electrophoresis, Capillary | Humans | Spectrophotometry, Ultraviolet - standards | Ergotamine - urine | Polyethylene Glycols - chemistry | Surface-Active Agents - chemistry | Calibration | Ergotamine - standards | Saliva - chemistry | Pharmaceutical Preparations - analysis | Hydrogen-Ion Concentration
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8. Full Text Ergotamine and nicergoline – Facts and myths
by Zajdel, Paweł and Bednarski, Marek and Sapa, Jacek and Nowak, Gabriel
Pharmacological Reports, ISSN 1734-1140, 04/2015, Volume 67, Issue 2, pp. 360 - 363
Ergotamine, being a representative of naturally occurring ergoline alkaloids, derived from -lysergic acid, and nicergoline, a -lumilysergic acid derivative... 
Ergotamine | Biased signaling | Nicergoline | Valvunopathy | 5-HT2B agonism | agonism | 5-HT | DRUG | RECEPTOR | 5-HT2 | FEATURES | PHARMACOLOGY & PHARMACY | SEROTONIN | PHARMACOLOGICAL-PROPERTIES | AGONIST | Ergotamine - adverse effects | Nicergoline - therapeutic use | Humans | Heart Valve Diseases - chemically induced | Ergotamine - therapeutic use | Ergotamine - pharmacology | Nicergoline - adverse effects | Nicergoline - pharmacology
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9. Ergotamine in the acute treatment of migraine: A review and European consensus
by Tfelt-Hansen, P and Saxena, PR and Dahloef, C and Pascual, J and Lainez, M and Henry, P and Diener, H-C and Schoenen, J and Ferrari, MD and Goadsby, PJ
Brain, ISSN 0006-8950, 01/2000, Volume 123, Issue 1, pp. 9 - 18
Ergotamine has been used in clinical practice for the acute treatment of migraine for over 50 years, but there has been little agreement on its place in... 
ergotamine
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10. Full Text Structure and function of serotonin G protein-coupled receptors
by McCorvy, John D and Roth, Bryan L
Pharmacology and Therapeutics, ISSN 0163-7258, 06/2015, Volume 150, pp. 129 - 142
Serotonin receptors are prevalent throughout the nervous system and the periphery, and remain one of the most lucrative and promising drug discovery targets... 
5-HT2B | GPCR | 5-HT1B | β-Arrestin | Serotonin | Functional selectivity | 5-HT | BETA ADRENERGIC-RECEPTOR | RESOLUTION CRYSTAL-STRUCTURE | PHARMACOLOGICAL CHARACTERIZATION | VALVULAR HEART-DISEASE | LIGAND-BINDING SITES | MUSCARINIC ACETYLCHOLINE-RECEPTOR | RAT STOMACH FUNDUS | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | MOLECULAR-CLONING | beta-Arrestin | ADENYLATE-CYCLASE | Vasoconstrictor Agents - pharmacology | Vasoconstrictor Agents - therapeutic use | GTP-Binding Proteins - physiology | Signal Transduction | Receptor, Serotonin, 5-HT2B - metabolism | Humans | Models, Molecular | Ergotamine - therapeutic use | Receptors, Serotonin - chemistry | Migraine Disorders - drug therapy | Receptors, Serotonin - metabolism | Migraine Disorders - metabolism | Serotonin Receptor Agonists - pharmacology | Receptor, Serotonin, 5-HT2B - chemistry | Serotonin Receptor Agonists - therapeutic use | Animals | Heart Valve Diseases - metabolism | Allosteric Site | Receptor, Serotonin, 5-HT1B - chemistry | Protein Conformation | Receptor, Serotonin, 5-HT1B - metabolism | Heart Valve Diseases - drug therapy | Ergotamine - pharmacology | Phenols | G proteins | Index Medicus | 7TM | serotonin | β-arrestin | ligand bias | functional selectivity
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11. Full Text Trigeminal autonomic cephalalgias: Current and future treatments - Commentary
by Dodick, David W and Schwedt, Todd J and Trentman, Terrence L and Zimmerman, Richard S and Hentz, Joseph
Headache, ISSN 0017-8748, 06/2007, Volume 47, Issue 6, pp. 981 - 986
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12. Ergotamine alters plasma concentrations of glucagon, insulin, cortisol, and triiodothyronine in cows
by Browning, R Jr and Gissendanner, SJ and Wakefield, T Jr
Journal of Animal Science, ISSN 0021-8812, 03/2000, Volume 78, Issue 3, pp. 690 - 698
Bovine plasma was assayed to determine whether ergotamine, an ergopeptide isolated from endophytic tall fescue, affected cortisol, triiodothyronine, insulin,... 
ergotamine
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13. An unusual case of clarithromycin associated ergotism
by Ausband, SC and Goodman, PE
Journal of Emergency Medicine, ISSN 0736-4679, 11/2001, Volume 21, Issue 4, pp. 411 - 413
A 41-year-old woman presented to the Emergency Department complaining of a 4-day history of worsening lower leg pain, pallor, and a sensation of coolness... 
ergotamine
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14. Full Text Ergotamine and Dihydroergotamine: History, Pharmacology, and Efficacy
by Silberstein, Stephen D and McCrory, Douglas C
Headache: The Journal of Head and Face Pain, ISSN 0017-8748, 02/2003, Volume 43, Issue 2, pp. 144 - 166
Ergotamine and dihydroergotamine share structural similarities with the adrenergic, dopaminergic, and serotonergic neurotransmitters. As a result, they have... 
DHE | ergotamine | guidelines | serotonin | dihydroergotamine | Ergotamine | Dihydroergotamine | Serotonin | Guidelines | NASAL SPRAY | TARTRATE | SUBCUTANEOUS SUMATRIPTAN | CLINICAL NEUROLOGY | COMPARATIVE TRIAL | MIGRAINE ATTACKS | EMERGENCY TREATMENT | NAPROXEN SODIUM | HEADACHE | INTRAVENOUS DIHYDROERGOTAMINE | CEREBRAL-BLOOD-FLOW | Vasoconstrictor Agents - pharmacology | Vasoconstrictor Agents - therapeutic use | Dihydroergotamine - therapeutic use | United States | History, 20th Century | Humans | Receptors, Serotonin - drug effects | Ergotamine - therapeutic use | Treatment Outcome | Dihydroergotamine - history | Migraine Disorders - drug therapy | Dihydroergotamine - pharmacology | Animals | History, 19th Century | Ergotamine - pharmacology | Ergotamine - history | Vasoconstrictor Agents - history
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