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British Journal of Clinical Pharmacology, ISSN 0306-5251, 09/2013, Volume 76, Issue 3, pp. 455 - 466
Aims The anticoagulant rivaroxaban is an oral, direct Factor Xa inhibitor for the management of thromboembolic disorders. Metabolism and excretion involve... 
P‐glycoprotein | rivaroxaban | drug interactions | cytochrome P450 | healthy subjects | P-glycoprotein | Rivaroxaban | Healthy subjects | Cytochrome P450 | Drug interactions | BAY-59-7939 | SAFETY | PREVENTION | PHARMACODYNAMICS | PROTEASE INHIBITORS | IN-VITRO | FACTOR-XA INHIBITOR | ERYTHROMYCIN | PHARMACOLOGY & PHARMACY | LIVER-MICROSOMES | Anticoagulants - administration & dosage | Cytochrome P-450 Enzyme Inhibitors | Erythromycin - pharmacology | Ketoconazole - administration & dosage | Humans | Middle Aged | Cytochrome P-450 Enzyme System - metabolism | Midazolam - administration & dosage | Substrate Specificity | Metabolic Clearance Rate | Thiophenes - administration & dosage | Ketoconazole - pharmacology | Enzyme Inhibitors - administration & dosage | Young Adult | Drug Interactions | Enzyme Inhibitors - pharmacokinetics | Clarithromycin - pharmacokinetics | Clarithromycin - administration & dosage | Adult | Morpholines - administration & dosage | Enzyme Inhibitors - pharmacology | Ketoconazole - pharmacokinetics | Midazolam - pharmacokinetics | Cytochrome P-450 CYP3A - administration & dosage | Erythromycin - administration & dosage | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Thiophenes - pharmacokinetics | Erythromycin - pharmacokinetics | Cytochrome P-450 CYP3A - metabolism | Adolescent | Anticoagulants - pharmacokinetics | Morpholines - pharmacokinetics | Clarithromycin - pharmacology | Midazolam - pharmacology | Ketoconazole | Protease inhibitors | Fluconazole | Proteases | Cytochrome P-450 | Dosage and administration | Anticoagulants (Medicine) | Erythromycin | Thromboembolism | Index Medicus
Journal Article
The American Journal of Cardiology, ISSN 0002-9149, 2004, Volume 94, Issue 9, pp. 1140 - 1146
Three-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors (statins) are first-line treatments for hypercholesterolemia. Although exceedingly well... 
CLARITHROMYCIN | INDUCED RHABDOMYOLYSIS | LOVASTATIN | CARDIAC & CARDIOVASCULAR SYSTEMS | CONCOMITANT USE | ERYTHROMYCIN | FATAL RHABDOMYOLYSIS | ITRACONAZOLE | ROSUVASTATIN | DRUG-INTERACTION | CYCLOSPORINE | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Pyrroles - pharmacokinetics | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 Enzyme System - administration & dosage | Area Under Curve | Heptanoic Acids - pharmacokinetics | Humans | Middle Aged | Mibefradil - pharmacokinetics | Male | Protein Synthesis Inhibitors - administration & dosage | Verapamil - administration & dosage | Dose-Response Relationship, Drug | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Antiprotozoal Agents - pharmacokinetics | Drug Interactions | Itraconazole - pharmacokinetics | Pyrroles - administration & dosage | Clarithromycin - pharmacokinetics | Mibefradil - administration & dosage | Clarithromycin - administration & dosage | Heptanoic Acids - administration & dosage | Adult | Female | Itraconazole - administration & dosage | Drug Therapy, Combination | Double-Blind Method | Simvastatin - administration & dosage | Verapamil - pharmacokinetics | Biomarkers - blood | Simvastatin - pharmacokinetics | Protein Synthesis Inhibitors - pharmacokinetics | Atorvastatin Calcium | Anticholesteremic Agents - pharmacokinetics | Pravastatin - administration & dosage | Anticholesteremic Agents - administration & dosage | Adolescent | Antiprotozoal Agents - administration & dosage | Calcium Channel Blockers - administration & dosage | Creatine Kinase - drug effects | Calcium Channel Blockers - pharmacokinetics | Pravastatin - pharmacokinetics
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/2016, Volume 82, Issue 6, pp. 1591 - 1600
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2006, Volume 80, Issue 3, pp. 203 - 215
Journal Article
Drug Safety, ISSN 0114-5916, 6/2012, Volume 35, Issue 6, pp. 459 - 470
Journal Article
Drug Safety, ISSN 0114-5916, 9/2017, Volume 40, Issue 9, pp. 835 - 840
Digoxin is commonly prescribed to elderly patients with heart failure and atrial fibrillation, and macrolide antibiotics markedly increase the risk of digoxin... 
Medicine & Public Health | Drug Safety and Pharmacovigilance | Pharmacology/Toxicology | CLARITHROMYCIN | MANAGEMENT | HEART-FAILURE | GUIDELINES | CARDIAC-ARRHYTHMIA | AZITHROMYCIN | ATRIAL-FIBRILLATION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INHIBITION | INCREASED MORTALITY | PHARMACOLOGY & PHARMACY | UPDATE | TOXICOLOGY | Digoxin - adverse effects | Cefuroxime - adverse effects | Humans | Male | Azithromycin - administration & dosage | Case-Control Studies | Drug Interactions | Aged, 80 and over | Clarithromycin - administration & dosage | Female | Anti-Bacterial Agents - adverse effects | Cefuroxime - administration & dosage | Death, Sudden - epidemiology | Macrolides - administration & dosage | Atrial Fibrillation - drug therapy | Clarithromycin - adverse effects | Risk Factors | Erythromycin - administration & dosage | Heart Failure - drug therapy | Azithromycin - adverse effects | Erythromycin - adverse effects | Macrolides - adverse effects | Cardiotonic Agents - administration & dosage | Digoxin - administration & dosage | Aged | Anti-Bacterial Agents - administration & dosage | Ontario | Macrolide antibiotics | Usage | Dosage and administration | Sudden death | Risk factors | Elderly people | Heart | Cardiac arrhythmia | Clarithromycin | Digoxin | Toxicity | Azithromycin | Risk | Population studies | Confidence intervals | Cefuroxime | Fibrillation | Safety engineering | Population | Heart diseases | Heart failure | Statistical analysis | Risk groups | Mortality | Erythromycin | Patients | Studies | Prescription drugs | Antibiotics | Death | Health risk assessment | Elderly | Geriatrics
Journal Article
American Journal of Surgery, The, ISSN 0002-9610, 2011, Volume 202, Issue 2, pp. 225 - 232
Abstract Background Colon preparation for elective colon resection to reduce surgical site infection (SSI) remains controversial. Methods A review of the... 
Surgery | Mechanical bowel preparation | Sodium phosphate | Polyethylene glycol | Colon surgery | Surgical site infection | Oral antibiotics | Preventive antibiotics | SYSTEMIC ANTIBIOTICS | SURGERY | RANDOMIZED CLINICAL-TRIAL | WOUND-INFECTION | SODIUM-PHOSPHATE | PREOPERATIVE ORAL ANTIBIOTICS | ELECTROLYTE LAVAGE SOLUTION | NO PREPARATION | POLYETHYLENE-GLYCOL | ELECTIVE COLORECTAL SURGERY | Cathartics - history | Cathartics - administration & dosage | Drug Administration Schedule | Administration, Oral | Phosphates - administration & dosage | History, 20th Century | Humans | Metronidazole - administration & dosage | Colon - drug effects | Antibiotic Prophylaxis - methods | Treatment Outcome | Clinical Trials as Topic | Colectomy | Antibiotic Prophylaxis - adverse effects | Evidence-Based Medicine | Polyethylene Glycols - administration & dosage | Erythromycin - administration & dosage | Surgical Wound Infection - prevention & control | Anti-Bacterial Agents - adverse effects | Colon - microbiology | Surgical Wound Infection - microbiology | Odds Ratio | Anti-Bacterial Agents - administration & dosage | Elective Surgical Procedures | Phosphates | Health aspects | Polyols | Medical research | Clinical trials | Infections | Abdomen | Meta-analysis | Literature reviews | Prevention | Probiotics | Infectious diseases | Antibiotics | Surveillance | Intestine | Sepsis | Bacteria | Electrolytes | Colon | Colorectal surgery
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 09/2015, Volume 55, Issue 9, pp. 1012 - 1023
Journal Article
Journal of NeuroVirology, ISSN 1355-0284, 1996, Volume 2, Issue 5, pp. 345 - 355
We report here the results of therapeutic trials in 200 patients with HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) conducted in our... 
Therapy | HAM/TSP | Side effects | SPINAL-CORD LESIONS | INTERFERON-ALPHA TREATMENT | therapy | FOLLOW-UP | CEREBROSPINAL-FLUID | NEUROSCIENCES | VIROLOGY | THYROTROPIN-RELEASING-HORMONE | VIRUS TYPE-I | side effects | CENTRAL-NERVOUS-SYSTEM | PERIPHERAL-BLOOD LYMPHOCYTES | HAM TSP | T-CELLS | Paraparesis, Tropical Spastic - drug therapy | Azathioprine - administration & dosage | Injections, Intravenous | Humans | Middle Aged | Glycerol - administration & dosage | Male | Human T-lymphotropic virus 1 | Hydrocortisone - administration & dosage | Danazol - administration & dosage | Propiophenones - administration & dosage | Ribonucleosides - administration & dosage | Adult | Anti-Inflammatory Agents - administration & dosage | Female | Immunosuppressive Agents - administration & dosage | Respiratory Therapy | Injections, Spinal | Thyrotropin-Releasing Hormone - administration & dosage | Administration, Oral | Ascorbic Acid - administration & dosage | Injections, Intramuscular | Antiviral Agents - administration & dosage | Erythromycin - administration & dosage | Plasmapheresis | Sulfasalazine - administration & dosage | Estrogen Antagonists - administration & dosage | Leukapheresis | Anti-Infective Agents - administration & dosage | Fosfomycin - administration & dosage | Interferon-gamma - administration & dosage | Aged | Anti-Bacterial Agents - administration & dosage | Pentoxifylline - administration & dosage | Vasodilator Agents - administration & dosage | Immunoglobulins, Intravenous | Methylprednisolone - administration & dosage
Journal Article
Allergy, ISSN 0105-4538, 2011, Volume 66, Issue 11, pp. 1457 - 1468
Journal Article