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Journal Article
Blood, ISSN 0006-4971, 03/2016, Volume 127, Issue 10, pp. 1325 - 1335
Journal Article
Blood, ISSN 0006-4971, 04/2008, Volume 111, Issue 7, pp. 3751 - 3759
The V617F activating point mutation in Jak2 is associated with a proportion of myeloproliferative disorders. In normal hematopoietic cells, Jak2 signals only... 
GENOMIC INSTABILITY | HEMATOPOIETIC-CELLS | V617F MUTATION | POLYCYTHEMIA-VERA | ACTIVATING MUTATION | ERYTHROPOIETIN RECEPTOR | TYROSINE KINASE JAK2 | GENE-EXPRESSION | HEMATOLOGY | CHRONIC MYELOID-LEUKEMIA | TRANSGENIC MICE | Janus Kinase 2 - biosynthesis | Reactive Oxygen Species - metabolism | Humans | Hematopoiesis, Extramedullary - genetics | Myeloproliferative Disorders - pathology | Mutation, Missense | Proto-Oncogene Proteins - biosynthesis | Liver - embryology | Myeloproliferative Disorders - genetics | Receptors, Erythropoietin - genetics | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Proto-Oncogene Proteins c-myc - biosynthesis | Cell Transformation, Neoplastic - genetics | Myeloproliferative Disorders - metabolism | Erythropoietin - metabolism | Gene Expression Regulation, Neoplastic - genetics | Transduction, Genetic | Janus Kinase 2 - genetics | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Protein Structure, Tertiary - genetics | Signal Transduction - genetics | Cell Transformation, Neoplastic - metabolism | Protein-Serine-Threonine Kinases - biosynthesis | Erythropoietin - genetics | Animals | Cell Line, Tumor | Proto-Oncogene Proteins c-pim-1 - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Enzyme Activation - genetics | Receptors, Erythropoietin - metabolism | Proto-Oncogene Proteins c-pim-1 - biosynthesis | Index Medicus | Abridged Index Medicus | Neoplasia
Journal Article
Cardiovascular Research, ISSN 0008-6363, 03/2007, Volume 73, Issue 4, pp. 783 - 793
Objective: Clinical experimental stem cell therapy after myocardial infarction appears feasible, but its use has preceded the understanding of the working... 
Myocardial infarction | Angiogenesis | Cytokines | Gene expression | Growth factors | Stem cells | PROGENITOR CELLS | stem cells | ERYTHROPOIETIN | CARDIAC & CARDIOVASCULAR SYSTEMS | growth factors | MOBILIZATION | angiogenesis | REGENERATION | myocardial infarction | TRANSPLANTATION | HEART | REPAIR | cytokines | GROWTH-FACTOR | NEOVASCULARIZATION | gene expression | Immunohistochemistry | Intercellular Signaling Peptides and Proteins - analysis | Interleukin-8 - genetics | Myocardial Infarction - genetics | Myocardium - chemistry | Cytokines - analysis | Tumor Necrosis Factor-alpha - genetics | RNA, Messenger - analysis | Male | Interleukin-1beta - genetics | Vascular Endothelial Growth Factor A - genetics | Receptors, Erythropoietin - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Stem Cell Transplantation | Transforming Growth Factor beta - analysis | Ligation | Time Factors | Myocardial Infarction - pathology | Myocardium - metabolism | Models, Animal | Cytokines - genetics | Blotting, Western - methods | Chemokine CCL4 | Gene Expression | Chemokine CCL3 | Interleukin-6 - genetics | Vascular Endothelial Growth Factor Receptor-2 - analysis | Neovascularization, Physiologic - genetics | Mice, Inbred C57BL | Intercellular Signaling Peptides and Proteins - genetics | Chemokine CCL2 - genetics | Gene Expression Profiling - methods | Myocardium - pathology | Vascular Endothelial Growth Factor A - analysis | Myocardial Infarction - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Macrophage Inflammatory Proteins - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Microscopy, Confocal | Microdissection - methods | Animals | Transforming Growth Factor beta - genetics | Receptors, Erythropoietin - analysis | Interleukin-10 - genetics | Chemokines, CC - genetics | Stem Cells - physiology | Mice | Genetic research | Heart attack | Index Medicus
Journal Article
Diabetes, ISSN 0012-1797, 08/2012, Volume 61, Issue 8, pp. 2187 - 2194
Journal Article
Cancer Cell, ISSN 1535-6108, 2005, Volume 7, Issue 4, pp. 387 - 397
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 11/2015, Volume 409, Issue 1, pp. 255 - 262
Baculovirus expression vector system (BEVS) is widely used for production of recombinant eukaryotic proteins in insect larvae or cultured cells. BEVS has... 
Life Sciences | Biochemistry, general | ER chaperone | RNAi | Medical Biochemistry | Oncology | Baculovirus expression system | Recombinant protein | Cardiology | Silkworm | ER-ASSOCIATED DEGRADATION | QUALITY-CONTROL | STRESS | FAMILY | CELL BIOLOGY | Wnt3A Protein - metabolism | RNA, Small Interfering - genetics | Molecular Chaperones - metabolism | Wnt3A Protein - secretion | Hepatocyte Growth Factor - secretion | Baculoviridae - metabolism | Protein Disulfide-Isomerases - metabolism | Humans | Endoplasmic Reticulum - metabolism | Baculoviridae - genetics | Calreticulin - genetics | Calnexin - genetics | Heat-Shock Proteins - genetics | RNA, Messenger - biosynthesis | Bombyx - metabolism | RNA Interference | Calreticulin - metabolism | Hepatocyte Growth Factor - genetics | Erythropoietin - secretion | Calnexin - metabolism | Erythropoietin - metabolism | Cell Line | Cats | Wnt3A Protein - genetics | Recombinant Proteins - secretion | Heat-Shock Proteins - metabolism | RNA, Messenger - genetics | Molecular Chaperones - genetics | Recombinant Proteins - genetics | Bombyx - genetics | Genetic Vectors - genetics | Hepatocyte Growth Factor - metabolism | Erythropoietin - genetics | Protein Disulfide-Isomerases - genetics | Animals | Mice | Genomes | Glycoproteins | RNA | Recombinant proteins | Genomics | Proteins | Bacteria | Cellular biology | Worms | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2017, Volume 19, Issue 6, pp. 626 - 638
Advances in genomic profiling present new challenges of explaining how changes in DNA and RNA are translated into proteins linking genotype to phenotype. Here... 
MESSENGER-RNAS | HEMATOPOIETIC STEM-CELLS | MOUSE MODEL | TRANSCRIPTION | DIAMOND-BLACKFAN ANEMIA | GENE-EXPRESSION | L-LEUCINE IMPROVES | MASS-SPECTROMETRY | MTOR | SEQ | CELL BIOLOGY | Erythropoiesis | Mitochondria - enzymology | Protein Biosynthesis | TOR Serine-Threonine Kinases - metabolism | Humans | Multiprotein Complexes - genetics | Mitochondrial Proteins - genetics | RNA, Messenger - metabolism | Receptors, Erythropoietin - genetics | Mechanistic Target of Rapamycin Complex 1 | RNA - genetics | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Organelle Biogenesis | TOR Serine-Threonine Kinases - genetics | Transfection | RNA Interference | Mitochondrial Proteins - metabolism | Acetylation | Proteomics - methods | Repressor Proteins - metabolism | RNA - metabolism | PTEN Phosphohydrolase - genetics | High Mobility Group Proteins - metabolism | Signal Transduction | RNA, Messenger - genetics | Cells, Cultured | PTEN Phosphohydrolase - metabolism | Repressor Proteins - genetics | Gene Expression Profiling - methods | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, Knockout | Transcription Factors - metabolism | Phenotype | Animals | Histones - metabolism | Receptors, Erythropoietin - metabolism | Hematopoietic Stem Cells - enzymology | High Mobility Group Proteins - genetics | Post-transcription | Deregulation | Transcription factors | Profiling | Transcription | Gene regulation | Genomes | Biosynthesis | Defects | Proteins | Signal transduction | Mitochondria | Deoxyribonucleic acid--DNA | Translation | Pharmacology | Metabolism | Gene expression | Erythroid cells | Ribonucleic acid--RNA | Signaling | Stem cells | Cells (biology) | In vivo methods and tests | In vitro methods and tests | Index Medicus
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 11/2013, Volume 45, Issue 11, pp. 2359 - 2368
Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate the cellular response to low oxygen. Although HIF-1 is usually considered as the... 
Hypoxia | SOD2 | HIF-2α | EPO | Cobalt | USF2 | HIF-2 alpha | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIF-2-ALPHA EXPRESSION | FACTOR-I | HYPOXIA-INDUCIBLE FACTORS | CELL BIOLOGY | NUCLEAR ACCUMULATION | HEPATOCELLULAR-CARCINOMA | FACTOR 2-ALPHA | PROLYL-HYDROXYLASES | HYPOXIA-INDUCIBLE-FACTOR-1-ALPHA HIF-1-ALPHA | TARGET GENE | FACTOR (HIF)-1-ALPHA | Transcription, Genetic - drug effects | Protein Binding - genetics | Superoxide Dismutase - genetics | Humans | Amino Acids, Dicarboxylic - pharmacology | RNA, Messenger - metabolism | Promoter Regions, Genetic - genetics | Pyrrolidines - pharmacology | Cell Nucleus - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cobalt - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Upstream Stimulatory Factors - metabolism | Protein Binding - drug effects | Erythropoietin - secretion | Liver Neoplasms - pathology | Gene Expression Regulation, Neoplastic - drug effects | Phosphoglycerate Kinase - genetics | Deferoxamine - pharmacology | Cell Hypoxia - drug effects | Basic Helix-Loop-Helix Transcription Factors - genetics | Liver Neoplasms - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | RNA, Messenger - genetics | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Erythropoietin - genetics | Cell Line, Tumor | Cell Hypoxia - genetics | Cell Nucleus - drug effects | Propanolamines - pharmacology | Phosphoglycerate Kinase - metabolism | Liver cancer | Erythropoietin | Genes | Genetic aspects | Genetic transcription | Cancer | Index Medicus | Proteins | Activated | Activation | Gene expression
Journal Article
Human Mutation, ISSN 1059-7794, 01/2014, Volume 35, Issue 1, pp. 15 - 26
Journal Article