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PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, pp. e17540 - e17540
Background: Neural induction of human pluripotent stem cells often yields heterogeneous cell populations that can hamper quantitative and comparative analyses.... 
PROGENITOR CELLS | NERVOUS-SYSTEM | HUMAN ES | MULTIDISCIPLINARY SCIENCES | SPINAL-CORD | SELF-RENEWAL | FLOW-CYTOMETRIC ANALYSIS | DOPAMINERGIC-NEURONS | DIFFERENTIATION | FETAL | HUMAN BLASTOCYSTS | Cell Proliferation | Antibodies - metabolism | Humans | Neurons - cytology | Neural Stem Cells - cytology | Antigens, CD - metabolism | Neuroglia - cytology | Spinal Cord - pathology | Neural Stem Cells - transplantation | Cell Differentiation | Cell Membrane - metabolism | Neurons - metabolism | Biomarkers - metabolism | Pluripotent Stem Cells - cytology | Cell Survival | Cells, Cultured | Rats | Cell Separation - methods | Rats, Sprague-Dawley | Pluripotent Stem Cells - metabolism | Phenotype | Animals | Models, Biological | Neuroglia - metabolism | Mice | Neural Stem Cells - metabolism | Viral antibodies | Antibodies | Comparative analysis | Cell differentiation | Embryonic stem cells | Neurons | Flow cytometry | Neurosciences | Populations | Transplants & implants | Image processing | Laboratories | Embryo cells | Fluorescence | Cell surface | Neuronal-glial interactions | CD44 antigen | Rodents | Paralysis | Signatures | Drug dosages | Astrocytes | Glial fibrillary acidic protein | Markers | Cultures | Embryos | Screens | Medicine | Studies | Brain research | Stem cells | Neural stem cells | CD18 antigen | Spinal cord injuries | Anesthesiology | Differentiation | Surface markers | Pluripotency | Cell culture | Mixed culture | Action potential | Glia | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, pp. e29597 - e29597
Human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC) provide new prospects for studying human neurodevelopment and modeling neurological... 
HUMAN ES | INHIBITION | FGF | MULTIDISCIPLINARY SCIENCES | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION CAPACITY | PRECURSORS | TRIPOTENT | Oligonucleotide Array Sequence Analysis | Humans | Fibroblast Growth Factor 2 - pharmacology | Neurons - cytology | Gene Expression Profiling | Neural Stem Cells - cytology | Neuroepithelial Cells - cytology | Neuroglia - cytology | Neurons - metabolism | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Cell Line | Pluripotent Stem Cells - cytology | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Cell Differentiation - drug effects | Fluorescent Antibody Technique | Neuroglia - metabolism | Cell Proliferation - drug effects | Neuroepithelial Cells - metabolism | Epidermal Growth Factor - pharmacology | Neural Stem Cells - metabolism | Cluster Analysis | Medical research | Nervous system diseases | Epidermal growth factor | Neurons | Medicine, Experimental | Fibroblast growth factors | Comparative analysis | Embryonic stem cells | Neurophysiology | Neurosciences | Laboratories | Neurobiology | Embryo cells | Radial glial cells | Nervous system | Biochemistry | Neurodevelopmental disorders | Neuronal-glial interactions | Genotype & phenotype | Fibroblasts | Physiology | Growth factors | Fibroblast growth factor 2 | Fetuses | Embryos | Brain research | Stem cells | Comparative studies | Hindbrain | Bayesian analysis | Pluripotency | Index Medicus
Journal Article
1970, Dunham lectures, 108 p. illus.
Book
Cell Reports, ISSN 2211-1247, 06/2012, Volume 1, Issue 6, pp. 703 - 714
To model human neural-cell-fate specification and to provide cells for regenerative therapies, we have developed a method to generate human neural progenitors... 
HUMAN ES | IN-VITRO | VENTRAL MESENCEPHALON | FLOOR PLATE | MIDBRAIN DOPAMINE NEURONS | SUBSTANTIA-NIGRA | RAT MODEL | LINES | PARKINSONS-DISEASE | IPS CELLS | CELL BIOLOGY | Body Patterning - drug effects | Organ Specificity - drug effects | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Humans | Cell Survival - genetics | Motor Activity - drug effects | Neurons - cytology | Neural Stem Cells - cytology | Cell Culture Techniques - methods | Cell Lineage - drug effects | Neural Tube - drug effects | Cell Differentiation - genetics | Organ Specificity - genetics | Dopamine - secretion | Dopaminergic Neurons - metabolism | Telencephalon - drug effects | Dopaminergic Neurons - drug effects | Neural Stem Cells - transplantation | Neurons - metabolism | Neurons - drug effects | Cell Lineage - genetics | Cell Survival - drug effects | Telencephalon - metabolism | Telencephalon - cytology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cells, Cultured | Neural Stem Cells - drug effects | Rats | Glycogen Synthase Kinase 3 - metabolism | Aging - pathology | Gene Expression Regulation - drug effects | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Embryonic Stem Cells - drug effects | Wnt Signaling Pathway - genetics | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Neural Tube - embryology | Body Patterning - genetics | Neural Stem Cells - metabolism | Electrophysiological Phenomena - drug effects | Index Medicus | Biological Sciences | Biologi | Naturvetenskap | Cellbiologi | Natural Sciences | Cell Biology
Journal Article
PLoS Biology, ISSN 1544-9173, 07/2009, Volume 7, Issue 7, pp. e1000149 - e1000149
There is evidence that pluripotency of mouse embryonic stem (ES) cells is associated with the activity of a network of transcription factors with Sox2, Oct4,... 
SYNERGISTIC ACTION | SOX2 | DEVELOPMENTAL REGULATORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE EMBRYOS | BIOLOGY | GENE-EXPRESSION | SELF-RENEWAL | PLURIPOTENCY | DIFFERENTIATION | ES CELLS | TRANSCRIPTIONAL REGULATION | Embryonic Stem Cells - cytology | Transcription Factors - chemistry | Homeodomain Proteins - metabolism | Gene Expression Profiling | Gene Regulatory Networks | SOXB1 Transcription Factors - metabolism | Flow Cytometry | SOXB1 Transcription Factors - chemistry | Transcription, Genetic | Tumor Cells, Cultured | Transgenes | Cell Differentiation - physiology | Genes, Reporter | Cell Line | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Octamer Transcription Factor-3 - chemistry | Embryonal Carcinoma Stem Cells - cytology | Pluripotent Stem Cells - physiology | Gene Expression Regulation | Homeodomain Proteins - chemistry | Embryonic Stem Cells - physiology | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Cell Lineage | Embryonal Carcinoma Stem Cells - physiology | Phenotype | Animals | Models, Biological | Octamer Transcription Factor-3 - metabolism | Mice | Cell culture | Index Medicus | Revistes | Medicina | Embryonic stem cells | Cèl·lules mare | Àrees temàtiques de la UPC | Ciències de la salut | Proteins | Cellular biology | Noise | Stem cells | Population | Gene expression | Embryos | Experiments
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0169899 - e0169899
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 24, pp. 9875 - 9880
The stochastic and elite models have been proposed for the mechanism of induced pluripotent stem (iPS) cell generation. In this study we report a system that... 
Adult stem cells | Induced pluripotent stem cells | Stromal cells | Stem cells | Cell lines | Muses | Embryonic stem cells | Cellular differentiation | Cells | Mesenchymal stem cells | TRA-1-81 | ES cells | mesenchymal stem cells | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | NICHE | GENERATION | INDUCTION | MARROW STROMAL CELLS | Adaptation, Physiological | Immunohistochemistry | Humans | Stress, Physiological | Antigens, CD - metabolism | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | Endoglin | Stage-Specific Embryonic Antigens - metabolism | Transfection | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Antigens, Surface - metabolism | Adult | Cell Differentiation | Dermis - cytology | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Cell Line | Cells, Cultured | Receptors, Cell Surface - metabolism | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Cell Lineage | Antigens, Tumor-Associated, Carbohydrate - metabolism | Animals | Octamer Transcription Factor-3 - metabolism | Mice, Inbred NOD | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Kruppel-Like Transcription Factors - genetics | Fibroblasts | Models | Research | Cell differentiation | Studies | Signal transduction | Antigens | Epigenetics | Viruses | Stochastic models | Index Medicus | Biological Sciences
Journal Article