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The Journal of infection, ISSN 0163-4453, 2014, Volume 69, Issue 3, pp. 216 - 225
Summary Background An intervention for Gram-negative bloodstream infections that integrated mass spectrometry technology for rapid diagnosis with antimicrobial stewardship oversight significantly... 
Infectious Disease | Bloodstream infections | Multidrug resistant | Antimicrobial stewardship | MALDI-TOF | Rapid diagnostics | MORTALITY | ACQUIRED INFECTIONS | INFECTIOUS DISEASES | METAANALYSIS | IDENTIFICATION | DISEASES SOCIETY | IMPACT | THERAPY | HEALTH-CARE | BLOOD-STREAM INFECTIONS | ENTEROBACTERIACEAE | Humans | Middle Aged | Bacteremia - mortality | Male | Pseudomonas Infections - mortality | Gram-Negative Bacterial Infections - microbiology | Time Factors | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Escherichia coli Infections - drug therapy | Escherichia coli - enzymology | Time-to-Treatment | Bacteremia - drug therapy | Klebsiella - enzymology | Gram-Negative Bacterial Infections - drug therapy | Pseudomonas Infections - diagnosis | Survival Rate | Pseudomonas Infections - microbiology | Klebsiella Infections - diagnosis | Gram-Negative Bacterial Infections - diagnosis | Hospital Costs | Escherichia coli Infections - mortality | Pseudomonas aeruginosa - isolation & purification | beta-Lactam Resistance | Acinetobacter Infections - mortality | Klebsiella - isolation & purification | Bacteremia - microbiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Drug Resistance, Multiple, Bacterial | Acinetobacter baumannii - isolation & purification | Adult | Female | beta-Lactamases - metabolism | Acinetobacter Infections - microbiology | Length of Stay | Escherichia coli Infections - diagnosis | Intensive Care Units | Klebsiella Infections - drug therapy | Acinetobacter Infections - diagnosis | Hospital Mortality | Pseudomonas Infections - drug therapy | Acinetobacter Infections - drug therapy | Escherichia coli Infections - microbiology | Treatment Outcome | Bacteremia - diagnosis | Klebsiella Infections - microbiology | Escherichia coli - isolation & purification | Klebsiella Infections - mortality | Aged | Gram-Negative Bacterial Infections - mortality | Drug resistance in microorganisms | Care and treatment | Mass spectrometry | Patient outcomes
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 484, Issue 7395, pp. 524 - 528
...). Here, we performed exudate leukocyte trafficking and mediator-metabololipidomics of murine peritoneal Escherichia coli infections with temporal identification of pro-inflammatory... 
RESPONSES | PHAGOCYTOSIS | INHIBITION | INFLAMMATION | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | RESOLUTION | INNATE | ACUTE LUNG INJURY | MICE | ASPIRIN | Hypothermia - prevention & control | Escherichia coli - drug effects | Humans | Male | Anti-Bacterial Agents - therapeutic use | Peritonitis - microbiology | Vancomycin - pharmacology | Staphylococcal Infections - microbiology | Macrophages - immunology | Staphylococcal Infections - metabolism | Escherichia coli Infections - drug therapy | Skin Diseases - microbiology | Staphylococcal Infections - drug therapy | Microbial Viability - drug effects | Skin Diseases - metabolism | Mice, Inbred C57BL | Peritonitis - metabolism | Neutrophils - immunology | Escherichia coli - immunology | Escherichia coli Infections - microbiology | Skin Diseases - drug therapy | Escherichia coli Infections - metabolism | Animals | Vancomycin - therapeutic use | Staphylococcus aureus - immunology | Anti-Bacterial Agents - pharmacology | Mice | Peritonitis - drug therapy | Staphylococcus aureus - drug effects | Phagocytosis | Docosahexaenoic Acids - metabolism | Escherichia coli | Staphylococcus aureus infections | Cross infection | Nosocomial infections | Ciprofloxacin | Health aspects | Staphylococcus aureus | Enzymes | Immunization | Bacterial infections | Microbiology | Antibiotics | E coli | Infections | Skin | Infectious Medicine | Infektionsmedicin
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 7, p. e69581
Community-acquired urinary tract infection (CA-UTI) is the most common infection caused by extended-spectrum beta-lactamase (ESBL... 
ESCHERICHIA-COLI STRAINS | NEW-ZEALAND | (ESBL)-PRODUCING ENTEROBACTERIA | MULTIDISCIPLINARY SCIENCES | NONHOSPITALIZED PATIENTS | LACTAMASE-PRODUCING ENTEROBACTERIACEAE | SPECTRUM BETA-LACTAMASES | BLOOD-STREAM INFECTIONS | KLEBSIELLA-PNEUMONIAE | EPIDEMIOLOGY | ONSET | Multivariate Analysis | Demography | Klebsiella pneumoniae - drug effects | Prevalence | Community-Acquired Infections - epidemiology | Escherichia coli - drug effects | Humans | Middle Aged | Male | beta-Lactamases - biosynthesis | Case-Control Studies | Anti-Bacterial Agents - therapeutic use | Klebsiella Infections - epidemiology | Community-Acquired Infections - drug therapy | Klebsiella pneumoniae - genetics | Female | Urinary Tract Infections - microbiology | Escherichia coli Infections - drug therapy | Escherichia coli - enzymology | Klebsiella Infections - drug therapy | Drug Resistance, Microbial - drug effects | Risk Factors | Escherichia coli Infections - microbiology | Genotype | Logistic Models | Klebsiella Infections - microbiology | Urinary Tract Infections - drug therapy | Escherichia coli Infections - epidemiology | Urinary Tract Infections - epidemiology | Escherichia coli - genetics | Norway - epidemiology | Klebsiella pneumoniae - enzymology | Anti-Bacterial Agents - pharmacology | Community-Acquired Infections - microbiology | Medical research | Medicine, Experimental | Urinary tract infections | Beta lactamases | Diabetes | Behavior | Health aspects | Prevalence studies (Epidemiology) | Fluoroquinolones | Laboratories | Communities | Amdinocillin | Diabetes mellitus | Fish meal | Population studies | Infections | Urinary tract | Risk analysis | Drug resistance | Epidemiology | Risk factors | Confidence intervals | Studies | E coli | Fish | Swimming | Meals | Community medicine, Social medicine: 801 | Samfunnsmedisin, sosialmedisin: 801 | VDP | Basic medical, dental and veterinary science disciplines: 710 | Medical microbiology: 715 | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medisinsk mikrobiologi: 715 | Medical disciplines: 700 | Basale medisinske, odontologiske og veterinærmedisinske fag: 710
Journal Article
The Journal of infectious diseases, ISSN 1537-6613, 2014, Volume 210, Issue 9, pp. 1357 - 1366
Background. Limitations in treatment of biofilm-associated bacterial infections are often due to subpopulation of persistent bacteria (persisters... 
Biofilms | Antibiotics | Escherichia coli | pH | Bacteria | Aminoglycosides | Pseudomonas aeruginosa | Infections | Basic amino acids | Staphylococcus aureus | aminoglycoside | persister | catheter-related infections | biofilm | proton motive force | DIAGNOSIS | INFECTIOUS DISEASES | INFECTIONS | MANAGEMENT | TOLERANCE | SUSCEPTIBILITY | MICROBIOLOGY | IMMUNOLOGY | ANTIBIOTIC-LOCK THERAPY | GENTAMICIN | PSEUDOMONAS-AERUGINOSA | L-ARGININE | GROWTH | Escherichia coli Infections - prevention & control | Central Venous Catheters - microbiology | Escherichia coli - drug effects | Gentamicins - administration & dosage | Catheter-Related Infections - prevention & control | Pseudomonas Infections - prevention & control | Arginine - administration & dosage | Gentamicins - pharmacology | Drug Therapy, Combination | Biofilms - drug effects | Escherichia coli Infections - drug therapy | Staphylococcal Infections - drug therapy | Pseudomonas Infections - drug therapy | Rats | Central Venous Catheters - adverse effects | Pseudomonas aeruginosa - drug effects | Catheter-Related Infections - drug therapy | Drug Synergism | Animals | Arginine - pharmacology | Staphylococcal Infections - prevention & control | Anti-Bacterial Agents - pharmacology | In Vitro Techniques | Staphylococcus aureus - drug effects | Hydrogen-Ion Concentration | Health aspects | Research | Index Medicus | Abridged Index Medicus | Biofilms/drug effects | Gentamicins/administration & dosage | Anti-Bacterial Agents/pharmacology | Staphylococcal Infections/drug therapy | Arginine/administration & dosage | Life Sciences | Escherichia coli Infections/drug therapy | Staphylococcus aureus/drug effects | Gentamicins/pharmacology | Catheter-Related Infections/prevention & control | Pseudomonas aeruginosa/drug effects | Staphylococcal Infections/prevention & control | Catheter-Related Infections/drug therapy | Central Venous Catheters/microbiology | Escherichia coli/drug effects | Bacteriology | Microbiology and Parasitology | Central Venous Catheters/adverse effects | Arginine/pharmacology | Pseudomonas Infections/prevention & control | Escherichia coli Infections/prevention & control | Pseudomonas Infections/drug therapy
Journal Article
Burns, ISSN 0305-4179, 2017, Volume 43, Issue 3, pp. 642 - 653
Highlights • Burn depth/agent increases risk of developing an infection. • Infections found folliculitis, burn wound, urinary tract, pneumonia, CVC and bloodstream... 
Critical Care | Nosocomial infection | Burn wound infection | Pneumonia | Urinary tract infection | Health care related infection | Burns | URINARY-TRACT-INFECTION | MORTALITY | SURGERY | RISK-FACTORS | DERMATOLOGY | REPLACEMENT | BACTERIOLOGY | CATHETERS | INTENSIVE-CARE-UNIT | SURVEILLANCE | ASSOCIATION | BLOOD-STREAM INFECTIONS | CRITICAL CARE MEDICINE | Escherichia coli | Humans | Middle Aged | Child, Preschool | Male | Young Adult | Folliculitis - epidemiology | Aged, 80 and over | Urinary Tract Infections - microbiology | Catheter-Related Infections - epidemiology | Child | Infant, Newborn | Staphylococcus aureus | Escherichia coli Infections - drug therapy | Bacteremia - drug therapy | Pseudomonas Infections - microbiology | Wound Infection - epidemiology | Catheter-Related Infections - drug therapy | Drug Resistance, Microbial | Escherichia coli Infections - epidemiology | Acinetobacter baumannii | Catheter-Related Infections - microbiology | Adolescent | Bacteremia - epidemiology | Infant | Bacteremia - microbiology | Cephalosporins - therapeutic use | Anti-Bacterial Agents - therapeutic use | Klebsiella Infections - epidemiology | Adult | Female | Pseudomonas aeruginosa | Staphylococcal Infections - microbiology | Wound Infection - drug therapy | Acinetobacter Infections - microbiology | Staphylococcal Infections - drug therapy | Colombia - epidemiology | Klebsiella Infections - drug therapy | Central Venous Catheters | Pneumonia - epidemiology | Pseudomonas Infections - drug therapy | Acinetobacter Infections - drug therapy | Escherichia coli Infections - microbiology | Folliculitis - microbiology | Pneumonia - microbiology | Klebsiella Infections - microbiology | Oxacillin - therapeutic use | Burns - epidemiology | Urinary Tract Infections - drug therapy | Urinary Tract Infections - epidemiology | Pneumonia - drug therapy | Staphylococcal Infections - epidemiology | Pseudomonas Infections - epidemiology | Acinetobacter Infections - epidemiology | Wound Infection - microbiology | Aged | Folliculitis - drug therapy | Klebsiella pneumoniae | Development and progression | Burns and scalds | Surgery, Plastic | Health aspects | Staphylococcus aureus infections | Analysis | Bacterial pneumonia | Mortality | Urinary tract infections | Bacteria | Disease susceptibility | Antibacterial agents
Journal Article
Pediatrics (Evanston), ISSN 1098-4275, 2011, Volume 127, Issue 5, pp. 817 - 826
Journal Article
PloS one, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37281
Formation of resilient biofilms on medical devices colonized by pathogenic microorganisms is a major cause of health-care associated infection... 
ANTIBIOTIC-LOCK TECHNIQUE | CONTROLLED-TRIAL | DIAGNOSIS | THERAPY | BACTEREMIA | IN-VIVO | BIOLOGY | ACCESS SYSTEM | MICE | CANCER | BLOOD-STREAM INFECTIONS | Staphylococcal Infections - drug therapy | Cefazolin - therapeutic use | Gentamicins - therapeutic use | Biofilms - growth & development | Pseudomonas Infections - complications | Rats | Male | Equipment Contamination | Staphylococcal Infections - complications | Anti-Bacterial Agents - therapeutic use | Animals | Staphylococcus epidermidis | Immunosuppression - adverse effects | Catheters, Indwelling - adverse effects | Models, Animal | Pseudomonas aeruginosa | Catheterization, Central Venous - adverse effects | Escherichia coli Infections - complications | Medical research | Medical equipment | Bacterial infections | Escherichia coli | Staphylococcus aureus infections | Medicine, Experimental | Cross infection | Nosocomial infections | Health aspects | Physiological apparatus | Staphylococcus aureus | Pediatrics | Surgical implants | Bioluminescence | Medical innovations | Disseminated infection | Clinical trials | Infections | Microorganisms | E coli | Bacteria | Pathogens | Medical devices | Stability | Complications | Medical instruments | Staphylococcus infections | Disease control | Contamination | Catheters | Biofilms | Antibiotics | Colonization | Cefazolin/therapeutic use | Escherichia coli infections | Biofilms/growth & development | Central Venous/adverse effects | Life Sciences | Staphylococcal Infections/complications/drug therapy | Pseudomonas Infections/complications | Bloodstream infections | Immunosuppression/adverse effects | Bacterial biofilms | Gentamicins/therapeutic use | Catheterization | Indwelling/adverse effects | Escherichia coli Infections/complications | bacterial pathogens | Bacteriology | Microbiology and Parasitology | Animal | Models | Anti-Bacterial Agents/therapeutic use
Journal Article
Journal Article
PLoS biology, ISSN 1545-7885, 2017, Volume 15, Issue 6, p. e2001644
Antibiotic-resistant infections kill approximately 23,000 people and cost $20,000,000,000 each year in the United States alone despite the widespread use of small-molecule antimicrobial combination therapy... 
GRAM-NEGATIVE BACTERIA | ANTIMICROBIAL DRUG | ANTIBACTERIAL ACTIVITY | COMBINATION THERAPY | PLASMODIUM-FALCIPARUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI K-12 | BIOLOGY | NUCLEOSIDE DIPHOSPHATE KINASE | VIVO ZEBRAFISH ASSAYS | SOS RESPONSE | FLUCTUATION ANALYSIS | Trimethoprim - chemistry | Klebsiella pneumoniae - drug effects | Escherichia coli - drug effects | Embryo, Nonmammalian - drug effects | Reverse Transcriptase Inhibitors - chemistry | Anti-Infective Agents, Urinary - therapeutic use | Biological Assay | Trimethoprim - agonists | Anti-Infective Agents, Urinary - chemistry | Anti-Infective Agents, Urinary - pharmacology | Escherichia coli Infections - drug therapy | Bacterial Proteins - antagonists & inhibitors | Computational Biology | Trimethoprim - therapeutic use | Mutation Rate | Escherichia coli Infections - metabolism | Drug Synergism | Small Molecule Libraries | Klebsiella pneumoniae - growth & development | Anti-Bacterial Agents - pharmacology | Mutation | Folic Acid Antagonists - pharmacology | Folic Acid Antagonists - chemistry | Trimethoprim - pharmacology | Sulfamethizole - agonists | Embryo, Nonmammalian - metabolism | Klebsiella Infections - metabolism | Reverse Transcriptase Inhibitors - pharmacology | Zebrafish - embryology | Folic Acid Antagonists - therapeutic use | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Sulfamethizole - chemistry | Anti-Bacterial Agents - chemistry | Drug Resistance, Multiple, Bacterial | Sulfamethizole - pharmacology | Drug Design | Escherichia coli - metabolism | Sulfamethizole - therapeutic use | Escherichia coli - growth & development | Klebsiella pneumoniae - metabolism | Reverse Transcriptase Inhibitors - therapeutic use | Drug Therapy, Combination | Klebsiella Infections - drug therapy | Bacterial Proteins - genetics | Escherichia coli Infections - microbiology | Embryo, Nonmammalian - microbiology | Klebsiella Infections - microbiology | Animals | High-Throughput Screening Assays | Bacterial Proteins - metabolism | Pattern Recognition, Automated | Prevention | Dosage and administration | Antibiotics | Drug resistance | Klebsiella | Virulence | Homeostasis | Trimethoprim | Hydroxyurea | Identification | Biosynthesis | Infections | Urinary tract | Drug development | Synergism | Folic acid | Design | Immunology | Historical account | E coli | New combinations | Antibiotic resistance | Bacteria | Libraries | Deoxyribonucleic acid--DNA | Effectiveness | Bacterial infections | Mutants | Medicine | DNA biosynthesis | Pathology | Sulfamethizole | Collection | Zidovudine | Bypasses | Methods | Deoxyribonucleic acid | DNA
Journal Article