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Science, ISSN 0036-8075, 10/2010, Volume 330, Issue 6000, pp. 70 - 74
Taxol (paclitaxel) is a potent anticancer drug first isolated from the Taxus brevifolia Pacific yew tree. Currently, cost-efficient production of Taxol and its... 
Enzymes | Cellular metabolism | Terpenoids | Chemical engineering | Bioreactors | Plasmids | REPORTS | Operons | Biosynthesis | Indoles | Streams | YEAST | CYTOCHROME-P450 | TAXADIENE | CELLS | MULTIDISCIPLINARY SCIENCES | CONSTRUCTION | BIOSYNTHETIC GENES | STEP | OXYGENASES | LYCOPENE PRODUCTION | TERPENOIDS | Metabolomics | NADPH-Ferrihemoprotein Reductase - genetics | Erythritol - analogs & derivatives | Cytochrome P-450 Enzyme System - metabolism | Taxoids - metabolism | Organophosphorus Compounds - metabolism | Recombinant Fusion Proteins - metabolism | Farnesyltranstransferase - metabolism | Escherichia coli K12 - metabolism | Hemiterpenes - metabolism | Indoles - metabolism | Terpenes - metabolism | Erythritol - metabolism | Isomerases - genetics | Diterpenes - metabolism | NADPH-Ferrihemoprotein Reductase - metabolism | Paclitaxel - biosynthesis | Oxidation-Reduction | Fermentation | Taxus - enzymology | Metabolic Networks and Pathways - genetics | Genetic Engineering | Sugar Phosphates - metabolism | Farnesyltranstransferase - genetics | Cytochrome P-450 Enzyme System - genetics | Isomerases - metabolism | Escherichia coli K12 - genetics | Alkenes - metabolism | Escherichia coli K12 - enzymology | Physiological aspects | Research | Health aspects | Escherichia coli | Biological transport | Biochemistry | Pharmacology | E coli | Drugs | Pathways | Searching | Taxol | Modules | Modular | Pacific yew | Optimization | Index Medicus
Journal Article
Science, ISSN 0036-8075, 9/2011, Volume 333, Issue 6048, pp. 1445 - 1449
Bacterial chromosomes are confined in submicrometer-sized nucleoids. Chromosome organization is facilitated by nucleoid-associated proteins (NAPs), but the... 
Proteins | Molecules | DNA | Genes | Imaging | REPORTS | Cell lines | Genetic loci | Gene expression regulation | Genomes | Chromosomes | CELLS | STRUCTURING PROTEIN | CAULOBACTER-CRESCENTUS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | GENE-EXPRESSION | OPTICAL RECONSTRUCTION MICROSCOPY | H-NS PROTEIN | BINDING | GENOME | Molecular Chaperones - metabolism | DNA, Bacterial - metabolism | Factor For Inversion Stimulation Protein - metabolism | Fimbriae Proteins - metabolism | Protein Multimerization | DNA, Bacterial - chemistry | Genetic Loci | Recombinant Fusion Proteins - metabolism | Escherichia coli K12 - ultrastructure | DNA-Binding Proteins - metabolism | Integration Host Factors - metabolism | Chromosomes, Bacterial - metabolism | Escherichia coli K12 - metabolism | Cell Division | Nucleic Acid Conformation | Binding Sites | Repressor Proteins - metabolism | Protein Structure, Tertiary | Genome, Bacterial | Repressor Proteins - chemistry | Operon | Repressor Proteins - genetics | Escherichia coli Proteins - metabolism | Chromosomes, Bacterial - ultrastructure | Fimbriae Proteins - genetics | Escherichia coli Proteins - genetics | Fimbriae Proteins - chemistry | Escherichia coli K12 - genetics | Escherichia coli Proteins - chemistry | Gene Expression Regulation, Bacterial | Cellular proteins | Research | Properties | Bacterial genetics | E coli | Microbiology | Bacterial proteins | Index Medicus
Journal Article
Science, ISSN 0036-8075, 8/2008, Volume 321, Issue 5891, pp. 960 - 964
Prokaryotes acquire virus resistance by integrating short fragments of viral nucleic acid into clusters of regularly interspaced short palindromic repeats... 
Bacteriophages | Proteins | Phenotypes | RNA | Microbiology | Prokaryotes | Genes | Antivirals | Viruses | Reports | Nucleotides | SYSTEM | STREPTOCOCCUS-THERMOPHILUS | ELEMENTS | EVOLUTIONARY | DNA | MULTIDISCIPLINARY SCIENCES | SEQUENCE | PROVIDES ACQUIRED-RESISTANCE | IDENTIFICATION | REPEATS | VIRUSES | DNA, Intergenic | Escherichia coli K12 - virology | Amino Acid Sequence | Genes, Bacterial | RNA, Guide - genetics | RNA, Guide - metabolism | DNA, Viral - metabolism | Molecular Sequence Data | Viral Plaque Assay | Escherichia coli Proteins - metabolism | Escherichia coli K12 - metabolism | Escherichia coli - genetics | Base Sequence | Escherichia coli - metabolism | Escherichia coli Proteins - genetics | RNA, Bacterial - genetics | Repetitive Sequences, Nucleic Acid | RNA Precursors - metabolism | Transcription, Genetic | Bacteriophage lambda - genetics | Escherichia coli K12 - genetics | Escherichia coli Proteins - chemistry | Bacteriophage lambda - growth & development | RNA, Bacterial - metabolism | Physiological aspects | Genetic aspects | Virus inhibitors | Infections | Ribonucleic acid--RNA | Index Medicus | Genetik | CRISPR | Naturvetenskap | Biokemi | Mikrobiologi | Genetics | Biochemistry | Natural Sciences | repeats | sequence | viruses | streptococcus-thermophilus | identification | system | dna | elements | evolutionary | provides acquired-resistance
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2013, Volume 41, Issue 1, pp. D605 - D612
Journal Article
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 10/2014, Volume 42, Issue 18, pp. 11383 - 11392
Journal Article