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Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7322, pp. 439 - 442
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2009, Volume 5, Issue 12, pp. 913 - 919
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 500, Issue 7460, pp. 102 - 106
The multidrug efflux transporter AcrB and its homologues are important in the multidrug resistance of Gram-negative pathogens(1,2). However, despite efforts to... 
GRAM-NEGATIVE BACTERIA | EFFLUX PUMP INHIBITORS | PSEUDOMONAS-AERUGINOSA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | RESISTANCE | TRANSPORTER ACRB | BINDING POCKET | SITE-DIRECTED MUTAGENESIS | STRATEGIES | Pyridines - chemistry | Protein Multimerization | Crystallography, X-Ray | Pyrimidinones - metabolism | Pyrimidines - chemistry | Pyrimidines - metabolism | Pyrimidinones - chemistry | Pseudomonas aeruginosa - metabolism | Anti-Bacterial Agents - chemistry | Membrane Transport Proteins - metabolism | Pyrimidinones - pharmacology | Escherichia coli Proteins - antagonists & inhibitors | Binding Sites | Bacterial Outer Membrane Proteins - antagonists & inhibitors | Multidrug Resistance-Associated Proteins - chemistry | Bacterial Outer Membrane Proteins - chemistry | Models, Molecular | Anti-Bacterial Agents - metabolism | Escherichia coli Proteins - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Pyrimidines - pharmacology | Escherichia coli - chemistry | Rotation | Membrane Transport Proteins - chemistry | Pseudomonas aeruginosa - chemistry | Pyridines - metabolism | Bacterial Outer Membrane Proteins - metabolism | Hydrophobic and Hydrophilic Interactions | Anti-Bacterial Agents - pharmacology | Pyridines - pharmacology | Escherichia coli Proteins - chemistry | Multidrug Resistance-Associated Proteins - metabolism | Drug resistance in microorganisms | Pseudomonas aeruginosa | Research | Structure | Identification and classification | Crystals | Physiological aspects | Microbiological research | Biological transport | Proteins | Antibiotics | Bacteriology | Crystal structure
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7606, pp. 277 - 280
In order to survive, bacteria continually sense, and respond to, environmental fluctuations. Stringent control represents a key bacterial stress response to... 
EF-TU | ELECTRON CRYOMICROSCOPY | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | CRYO-EM | TRANSFER-RNA | RIBONUCLEIC ACID SYNTHESIS | PROTEIN-SYNTHESIS | RELA | GUANOSINE TETRAPHOSPHATE | Guanosine Tetraphosphate - chemistry | Phosphorylation | Protein Biosynthesis | RNA, Transfer, Amino Acyl - chemistry | Stress, Physiological | Ribosomes - metabolism | Escherichia coli Proteins - ultrastructure | RNA, Transfer - ultrastructure | Guanosine Tetraphosphate - metabolism | Escherichia coli - pathogenicity | Escherichia coli - metabolism | RNA, Transfer, Amino Acyl - metabolism | GTP Pyrophosphokinase - metabolism | RNA, Transfer - genetics | Escherichia coli Proteins - antagonists & inhibitors | GTP Pyrophosphokinase - ultrastructure | RNA, Transfer - chemistry | Binding Sites | Second Messenger Systems | Protein Structure, Tertiary | GTP Pyrophosphokinase - antagonists & inhibitors | RNA, Transfer - metabolism | Ribosomes - chemistry | Models, Molecular | Escherichia coli Proteins - metabolism | RNA, Transfer, Amino Acyl - genetics | Amino Acids - deficiency | Cryoelectron Microscopy | Ribosomes - ultrastructure | Metabolic Networks and Pathways | Escherichia coli - genetics | Adenosine - metabolism | GTP Pyrophosphokinase - genetics | Protein Conformation | Escherichia coli Proteins - chemistry | Gene Expression Regulation, Bacterial | Escherichia coli - ultrastructure | Microbiological research | Transcription factors | Escherichia coli | Ribosomes | Research | Virulence (Microbiology) | Transfer RNA | E coli | Antibiotics | Ribonucleic acid--RNA | Crystal structure
Journal Article
Science, ISSN 0036-8075, 1/2009, Volume 323, Issue 5912, pp. 396 - 401
Journal Article
The EMBO Journal, ISSN 0261-4189, 10/2014, Volume 33, Issue 20, pp. 2408 - 2421
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2014, Volume 58, Issue 2, pp. 722 - 733
Journal Article